COVID-19 rebound following Paxlovid treatment likely due to insufficient drug exposure, UC San Diego researchers find after showing rebound patient did not show drug resistance or impaired immunity.

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COVID-19 rebound following Paxlovid treatment likely due to insufficient drug exposure, UC San Diego researchers find after showing rebound patient did not show drug resistance or impaired immunity.
Prescott Woodruff, MD, MPH, a renowned leader in the pathogenesis and treatment of airway disease, has been appointed chief of UC San Francisco’s Division of Pulmonary, Critical Care, Allergy and Sleep Medicine. Prescott will assume the role of chief on July 1.
UC San Diego researchers report significant decrease in national cases of Kawasaki disease during COVID-19 pandemic; findings hint at origins of disease.
An international team of researchers, led by scientists at University of California San Diego School of Medicine and the University of Pittsburgh, report promising results from the largest case series yet of patients treated with bacteriophage therapy for antibiotic-resistant infections.
COVID-19, MIS-C and KD all share a similar underlying mechanism involving the over-activation of particular inflammatory pathways, UC San Diego study shows. Findings support novel drug targets for MIS-C.
UC San Diego health experts weigh in on the impact of flavored tobacco products, the populations most vulnerable to them, and the recent efforts to ban their sale in San Diego and beyond On Monday, April 25, 2022, San Diego…
After more than 50 days on advanced life support, a multi-disciplinary team at UC San Diego Health helps a patient who contracted COVID-19 become a candidate for a successful double lung transplant. The transplant surgery was the first in the region performed on a COVID-19 patient.
UC San Diego Health, the region’s only academic health system, is ranked #1 in San Diego and #5 in California, placing it among the nation’s best hospitals, according to the 2021-2022 U.S. News & World Report survey. UC San Diego Health was ranked in the top 50 in 10 specialties.
Of the more than 3,000 U.S. hospitals evaluated, Rush University Medical Center ranked No. 19 in the nation by U.S. News & World Report, with nine of specialties rated among the country’s very best.
The lung transplant team at UC San Diego Health performed San Diego County’s first transplant surgery with lungs donated after cardiac death, an approach that could mean more opportunities to save the lives of those in critical need of new lungs.
Public health measures designed to reduce the spread of the COVID-19 virus may have fostered a substantial side benefit: A 53 percent drop in hospital admissions for chronic obstructive pulmonary disease (COPD), likely due to a drop in circulating seasonal respiratory viruses such as influenza.
Zea Borok, MD, has been named chair of the Department of Medicine at University of California San Diego School of Medicine. Her first day is April 1, 2021.
UC San Diego researchers find that an optical tool already embedded in many smartphones can accurately diagnose blood-oxygen levels and help monitor respiratory disease in patients, particularly when they are quarantined at home.
University of California San Diego Herbert Wertheim School of Public Health and Human Longevity Sciences researchers report that starting tobacco products, including e-cigarettes, before the age of 18 is a major risk factor for people becoming daily cigarette smokers.
UC San Diego Health’s lung, heart, kidney and liver transplant programs rank at the top nationally in the latest biannual Scientific Registry of Transplant Recipients (SRTR) report. Innovative treatment and multi-disciplinary care contribute to the high rankings for one-year survival outcomes.
UC San Diego researchers report chemicals used for flavor in e-cigarette liquid negatively affect specialized proteins that support immune system.
A team of American and Canadian researchers report that while they may feel uncomfortable, there is little empirical evidence that wearing a facemask significantly diminishes lung function, even when worn during heavy exercise.
Researchers with the Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center have secured $4 million in funding from the National Institutes of Health (NIH)/National Cancer Institute (NCI) to establish an HIV-associated Malignancy Research Center focused on lung cancer in East Africa.
Researchers at Children’s Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania have identified a cellular pathway that can be targeted with a naturally occurring drug to stimulate lung tissue regeneration, which is necessary for recovery from multiple lung injuries. The findings, which were published today in Nature Cell Biology, could lead to better therapies for patients with lung disease, including acute respiratory distress syndrome (ARDS) due to COVID-19.
Two UC San Diego School of Medicine-led analyses report that e-cigarettes are not effective in helping adults to quit smoking.
Researchers at University of California San Diego School of Medicine report that sleep may help people to learn continuously through their lifetime by encoding new memories and protecting old ones.
In the midst of the extraordinary health challenge presented by the COVID-19 pandemic, Baylor Scott & White Health remains committed to quality, safe care and helping Texas communities navigate the uncertainty of the SARS-CoV-2 virus. Today, this commitment to safety and quality is recognized as U.S. News & World Report releases its 2020-2021 Best Hospitals list.
UC San Diego Health is ranked first in San Diego and sixth in California, placing it among the nation’s best hospitals, according to the 2020-2021 U.S. News & World Report. Eight common procedures and conditions were also rated “high performing.”
Feeling sleepy, bookworms? Chances are you’re not alone. A new survey from the American Academy of Sleep Medicine (AASM) reveals that a majority (66%) of U.S. adults report losing sleep due to reading “past their bedtime.”
As we continue to grapple with the global pandemic, rising summer temperatures and wildfire season pose new challenges to our lung health. A team of pulmonologists and researchers at UC San Diego Health offer a wide variety of expertise and…
University Hospitals Cleveland Medical Center physicians completed evaluation for the GE Healthcare Critical Care Suite, and the technology is now in daily clinical practice – flagging between seven to 15 collapsed lungs per day within the hospital. No one on the team could have predicted the onset of the COVID-19 pandemic, but this technology and future research with GEHC may enhance the capability to improve care for COVID-19 patients in the ICU. Critical Care Suite is now assisting in COVID and non-COVID patient care as the AMX 240 travels to intensive care units within the hospital.
For the first time, surgeons at Northwestern Medicine performed a double-lung transplant on a patient whose lungs were damaged by COVID-19. The patient, a Hispanic woman in her 20s, spent six weeks in the COVID ICU on a ventilator and extracorporeal membrane oxygenation (ECMO), a life support machine that does the work of the heart and lungs.
UNC-Chapel Hill researchers show how SARS-CoV-2 infects the nasal cavity to a great degree, and progressively less so lower down the respiratory tract, suggesting the virus tends to become firmly established first in the nasal cavity, but can be aspirated into the lungs to cause serious disease.
UC San Diego Health has deployed a mobile ECMO life support system to help sustain critically-ill patients during the pandemic.
UC San Diego Health has launched a Phase III clinical trial to assess whether a medication used to treat rheumatoid might also have therapeutic value for patient with COVID-19 who have developed or are at high risk of developing serious lung damage from SARS-CoV-2 infections.
While COVID-19 has touched the lives of everyone, some people have been more affected than others. We asked UCLA Health experts from cardiology, pulmonology, oncology, mental health, internal medicine and diet and nutrition to weigh in on how people in high-risk groups,…
Researchers at UC San Diego Health publish the first empirical findings that strongly associate sensory loss and COVID-19, the respiratory disease caused by the novel coronavirus.
With support from Amazon Web Services, UC San Diego Health physicians are using AI in a clinical research study aimed at speeding the detection of pneumonia, a condition associated with severe COVID-19.
redirect to event registration Newswise Live Expert Panel discussion of unique angles to the COVID-19 outbreak of interest to the public and the media, including public health, testing, business and financial markets, 2020 elections, and more. Experts from institutions…
A new Cleveland Clinic study has uncovered a genetic anomaly associated with poor response to a common asthma treatment. The findings, published in Proceedings of the National Academy of Sciences, showed that asthmatic patients with the gene variant are less likely to respond to glucocorticoids and often develop severe asthma.
People with cystic fibrosis who carry genetic variants that lower RNF5 gene expression have more mutant CFTR protein on cell surfaces. Even if the CFTR protein isn’t fully functional, it’s better than none, and may explain why some with cystic fibrosis are less prone to infection than others.
The procedure, called Endobronchial Lung Volume Reduction (ELVR), is for patients with emphysema who have hyperinflated lungs. These patients can inhale but have difficulty exhaling because air trapped in their lungs causes them to become hyperinflated. Until now, such patients were typically treated with inhalers, lung surgery to reduce volume or lung transplants.
It’s Lung Cancer Awareness Month and there are few stories about women who are diagnosed with lung cancer. Here’s one story about a 42-year-old, non-smoking Mom of two who was surprised with a lung cancer diagnosis last Thanksgiving. The story also features tips from a UCLA pulmonologist on the signs and symptoms of lung cancer.
Experts at Beth Israel Deaconess Medical Center share tips for quitting smoking
In August, the Centers for Disease Control (CDC) issued a warning about a growing epidemic — lung injury caused by vaping. There have been more than 380 cases reported nationwide, with half of these patients requiring intensive care, and at…
In August, the Centers for Disease Control (CDC) issued a warning about a growing epidemic — lung injury caused by vaping. There have been more than 380 cases reported nationwide, with half of these patients requiring intensive care, and at…
The number of teens and young adults treated for severe respiratory injury after e-cigarette use is increasing at Monroe Carell Jr. Children’s Hospital at Vanderbilt, which is consistent with a nationwide trend that led to a recent communication to physicians from the Centers for Disease Control and Prevention (CDC).
$3.4 Million Study to Understand Why Older Adults Have Worse Asthma Outcomes