Study Identifies Genetic Anomaly Associated with Poor Response to Common Asthma Treatment

A new Cleveland Clinic study has uncovered a genetic anomaly associated with poor response to a common asthma treatment. The findings, published in Proceedings of the National Academy of Sciences, showed that asthmatic patients with the gene variant are less likely to respond to glucocorticoids and often develop severe asthma.

Read more

Modifier Gene May Explain Why Some with Cystic Fibrosis are Less Prone to Infection

People with cystic fibrosis who carry genetic variants that lower RNF5 gene expression have more mutant CFTR protein on cell surfaces. Even if the CFTR protein isn’t fully functional, it’s better than none, and may explain why some with cystic fibrosis are less prone to infection than others.

Read more

VUMC Offering New Minimally Invasive Emphysema Therapy

The procedure, called Endobronchial Lung Volume Reduction (ELVR), is for patients with emphysema who have hyperinflated lungs. These patients can inhale but have difficulty exhaling because air trapped in their lungs causes them to become hyperinflated. Until now, such patients were typically treated with inhalers, lung surgery to reduce volume or lung transplants.

Read more

Lung Cancer in Women – UCLA Health Pulmonologist describes the signs & symptoms of this deadly disease

It’s Lung Cancer Awareness Month and there are few stories about women who are diagnosed with lung cancer. Here’s one story about a 42-year-old, non-smoking Mom of two who was surprised with a lung cancer diagnosis last Thanksgiving. The story also features tips from a UCLA pulmonologist on the signs and symptoms of lung cancer.

Read more