Tag: MIS-C

Research Identifies Potential Genetic Cause for MIS-C Complication Following COVID-19 Infection

sarah JonasResearch Results

New research findings have revealed an underlying genetic cause for why some children who have had COVID-19 infection develop Multisystem Inflammatory Syndrome in Children (MIS-C), a rare but potentially life-threatening disease.

The findings, published in Science, are the first potential genetic cause identified for MIS-C, a disease that typically occurs about four weeks after COVID-19 infection and has broad symptoms such as fever, vomiting and inflammation of the heart muscle that can lead to hospitalization. States have reported about 9,000 MIS-C cases, with 71 deaths, according to most recent Centers for Disease Control and Prevention numbers.

Long COVID in Kids: A Path to Recovery

sarah Jonasblog

A new service at Children’s Hospital Los Angeles is providing comprehensive care for children with a debilitating post-COVID condition. Some teens can’t get back to the sports they love. Other children can no longer get through a school day—or even walk up a flight of stairs. Still others feel “off”—and anxious and depressed, too.

COVID-19, MIS-C and Kawasaki Disease Share Same Immune Response

sarah JonasResearch Results

COVID-19, MIS-C and KD all share a similar underlying mechanism involving the over-activation of particular inflammatory pathways, UC San Diego study shows. Findings support novel drug targets for MIS-C.

Multisystem Inflammatory Syndrome in Children (MIS-C) Clinic Opens at Monroe Carell Jr. Children’s Hospital at Vanderbilt

sarah JonasFeature

Children who have experienced the rare and potentially life-threatening multisystem inflammatory syndrome in children (MIS-C), which can develop within four weeks of exposure to the virus that causes COVID-19, are being followed closely in a multidisciplinary clinic at Monroe Carell Jr. Children’s Hospital at Vanderbilt.

Wayne State research team developing AI model to aid in early detection of SARS-CoV2 in children

sarah JonasAnnouncement

Currently, there are no methods to discern the spectrum of COVID-19’s severity and predict which children with SARS-CoV-2 exposure will develop severe illness, including MIS-C. Because of this, there is an urgent need to develop a diagnostic modality to distinguish the varying phenotypes of disease and risk stratify disease.

New Grant Supports Rutgers Study Seeking to Identify Factors for Children at High Risk for Severe Illness from COVID-19

sarah JonasAnnouncement

New Brunswick, NJ — Rutgers researchers have been awarded $1.6 million from the National Institutes of Health in support of the creation of a national collaborative network seeking to identify risk and protective factors that may allow clinicians or public health…

Story Tips from Johns Hopkins Experts on COVID-19

sarah JonasResearch Results

Vaccines take time to work. After getting a COVID-19 vaccine, it takes a while for the immune system to fully respond and provide protection from the virus. For the Moderna and Pfizer COVID-19 vaccines, it takes up to two weeks after the second shot to become appropriately protected.

Study Finds That Children’s Immune Response Protects Against COVID-19

sarah JonasResearch Results

The first study comparing the immune responses of adults and children with COVID-19 has detected key differences that may contribute to understanding why children usually have milder disease than adults. The findings also have important implications for vaccines and drugs being developed to curb COVID-19. The study was published today in Science Translational Medicine and was conducted by scientists at Albert Einstein College of Medicine, Children’s Hospital at Montefiore (CHAM), and Yale University.

CHOP Researchers Find MIS-C Associated with Myocardial Injury

sarah JonasResearch Results

Using sensitive parameters to assess cardiac function, researchers at Children’s Hospital of Philadelphia (CHOP) have found that cardiac involvement in multisystem inflammatory syndrome in children (MIS-C) differs from Kawasaki disease (KD) and is associated with myocardial injury. The findings were published recently in the Journal of the American College of Cardiology.

CHOP Researchers Identify Lab Profiles that Differentiate MIS-C from COVID-19 in Children

sarah JonasResearch Results

Researchers from Children’s Hospital of Philadelphia (CHOP) report important data that differentiate MIS-C from severe COVID-19 in children and suggest that MIS-C is a post-infectious syndrome related to COVID-19 but distinct from KD. The findings were published today in The Journal of Clinical Investigation.

What Parents Should Know about Multisystem Inflammatory Syndrome in Children (MIS-C)

sarah JonasFeature Expert

MIS-C stands for multisystem inflammatory syndrome in children. Formerly called pediatric inflammatory multisystem syndrome, or PIMS, it describes a new health condition seen in children who have been infected with novel coronavirus, recovered from it and later have an immune response that results in symptoms of significant levels of inflammation in organ systems. MIS-C is similar in some ways to other inflammatory conditions like Kawasaki disease and toxic shock syndrome. Children who have MIS-C generally did not have obvious symptoms when they were infected with novel coronavirus, like cough, and generally were healthy prior to developing MIS-C.

New York State Department of Health Announces Study on Multisystem Inflammatory Syndrome in Children

sarah JonasResearch Results

The New York State Department of Health today announced that the Department has led a study on multisystem inflammatory syndrome in children (MIS-C) associated with COVID-19, which was published today in the New England Journal of Medicine. The Department collaborated with the University at Albany School of Public Health and the federal Centers for Disease Control and Prevention (CDC) to complete the study.