In a discovery that challenges long-held dogma in biology, researchers show that mammalian cells can convert RNA sequences back into DNA, a feat more common in viruses than eukaryotic cells.
More physical activity programming could mitigate the effects of stress and improve worker mental and emotional health.
Can people learn to better identify fake news about COVID-19—and if so, would they be less likely to share that fake story with others? Perhaps, but it may take more than simply priming them to think more critically beforehand.
Faculty from the McKelvey School of Engineering and the School of Medicine teamed up to design better grafts for dialysis patients.
The big holes in Swiss cheese help make it a tasty treat. Now, scientists at PPPL are adding tiny, Swiss-cheese-type holes to components to improve the process of bringing to Earth the fusion energy that powers the sun and stars.
Researchers report on how a diverse cohort of gynecologic cancer patients are affected by financial distress, also called “financial toxicity” in acknowledgment of the health hazards it can pose, in the International Journal of Gynecological Cancer.
A study led by University of Minnesota Twin Cities researchers uncovered a property of magnetic materials that will allow engineers to develop more efficient spintronic devices in the future. Spintronics focuses on using the magnetic “spin” property of electrons instead of their charge, which improves the speed and efficiency of devices used for computing and data storage.
Researchers at Washington University School of Medicine in St. Louis have identified the brain regions involved in choosing whether to find out if a bad event is about to happen.
UC San Diego School of Medicine researchers discovered gene expression patterns associated with pandemic viral infections, providing a map to help define patients’ immune responses, measure disease severity, predict outcomes and test therapies — for current and future pandemics.
Researchers from NUS have come up with a way to use one single device – such as a mobile phone or smart watch – to wirelessly power up to 10 wearables on a user. This novel method uses the human body as a medium for transmitting power. Their system can also harvest unused energy from electronics in a typical home or office environment to power the wearables.
Study shows that scent-enhanced virtual reality technologies, or OVR, can be a safe and effective integrative approach to target anxiety, stress, and pain when combined with standard inpatient psychiatric care.
Weight-loss surgery improves or resolves diseases including type 2 diabetes, heart disease and high blood pressure and can lead to significant and durable weight loss for many people, but the operation has largely been restricted to those with severe obesity, which means about 75 to 100 pounds overweight or a body mass index (BMI) of 35 or higher with an obesity-related disease.
A new study released today finds residents in several states with the highest obesity rates in the country are among the least likely to undergo weight-loss surgery, long considered the standard of care for severe obesity and related diseases including type 2 diabetes and heart disease.
The prevalence of genetic mutations associated with breast cancer in Black and white women is the same.
Los investigadores de Mayo Clinic y sus colegas de la Universidad de Minnesota demostraron que la COVID-19 exacerba las consecuencias nocivas de las células senescentes en el cuerpo. En estudios preclínicos, los fármacos senolíticos descubiertos en Mayo redujeron considerablemente la inflamación, la enfermedad y la mortalidad debida a la infección por covid en ratones ancianos. Los resultados se publican en la revista Science.
Os pesquisadores da Mayo Clinic e colegas da Universidade de Minnesota mostraram que o COVID-19 intensifica o impacto prejudicial das células senescentes no corpo. Em estudos pré-clínicos, os medicamentos senolíticos descobertos na Mayo reduziram significativamente a inflamação, a gravidade da doença e a mortalidade da infecção por COVID em camundongos mais velhos. Essas conclusões foram publicadas na revista Science.
أظهر باحثو مايو كلينك وزملاؤهم في جامعة مينيسوتا أن فيروس كورونا المستجد (كوفيد-19) يفاقم التأثير الضار للخلايا الشائخة في الجسم. ففي الدراسات ما قبل السريرية، قللت الأدوية المحللة لالشيخوخة التي تم اكتشافها في مايو بشكل كبير من الالتهاب والمرض والوفيات الناجمة عن عَدوى فيروس كورونا المستجد في الفئران الأكبر سنًا. النتائج منشورة في مجلة ساينس.
• The virus that causes COVID-19 can infect and replicate in human kidney cells, but this does not typically lead to cell death.
• Kidney cells that already have features of injury may be more easily infected and develop additional injury.
New findings include a significant increase in risk of death among patients who had recently had chemotherapy.
A new Cleveland Clinic-led study has identified mechanisms by which COVID-19 can lead to Alzheimer’s disease-like dementia. The findings, published in Alzheimer’s Research & Therapy, indicate an overlap between COVID-19 and brain changes common in Alzheimer’s, and may help inform risk management and therapeutic strategies for COVID-19-associated cognitive impairment.
A new study led by Washington University School of Medicine in St. Louis provides new guidance on the treatment of medulloblastoma, a pediatric brain cancer. Some aspects of radiation therapy may be reduced while still providing effective treatment.
New research from the University of Notre Dame shows that “disagreeable” men in opposite-sex marriages are less helpful with domestic work, allowing them to devote greater resources to their jobs, which results in higher pay.
Researchers from Cornell University’s School of Applied and Engineering Physics and Samsung’s Advanced Institute of Technology have created a first-of-its-kind metalens – a metamaterial lens – that can be focused using voltage instead of mechanically moving its components.
Using an ultrafast transmission electron microscope, researchers from the Technion – Israel Institute of Technology have, for the first time, recorded the propagation of combined sound and light waves in atomically thin materials.
Pairing sky-mapping algorithms with advanced immunofluorescence imaging of cancer biopsies, researchers at The Mark Foundation Center for Advanced Genomics and Imaging at Johns Hopkins University and the Bloomberg~Kimmel Institute for Cancer Immunotherapy developed a robust platform to guide immunotherapy by predicting which cancers will respond to specific therapies targeting the immune system.
The Uttarakhand region of India experienced a humanitarian tragedy on Feb. 7, 2021, when a wall of debris and water barreled down the Ronti Gad, Rishiganga and Dhauliganga river valleys. This debris flow destroyed two hydropower facilities and left more than 200 people dead or missing. A self-organized coalition of 53 scientists, including researchers from the University of Washington, came together in the days following the disaster to investigate the cause, scope and impacts.
New paper explores links among the diet, gut microbiota and health status.
With the increase in demand for flexible wearable electronics, researchers have explored flexible energy storage devices, such as flexible supercapacitators, that are lightweight and safe and easily integrate with other devices. Printing electronics has proved to be an economical, simple, and scalable strategy for fabricating FSCs. In Applied Physics Reviews, researchers provide a review of printed FSCs in terms of ability to formulate functional inks, design printable electrodes, and integrate functions with other electronic devices.
Evidence suggests auditory and vestibular effects should be added to the growing list of physiological impacts of COVID-19. During the 180th Meeting, Colleen Le Prell from the University of Texas at Dallas will talk about hearing and balance disorders associated with coronavirus infection and how pandemic-related stress and anxiety may aggravate tinnitus symptoms. Her presentation, “Hearing disorders secondary to infection with SARS-CoV-2,” will take place Thursday, June 10.
Researchers from Tel Aviv University took part in a new international study proposing an amendment to the widely accepted theory on the extinction of animal species – by moving the focus from the animal’s body size to its reproductive capacity.
Lack of water, floods, or crop losses: As a result of climate change, pronounced periods of drought and rainfall are occurring more frequently and more intensively all around the world, causing human suffering and major economic damage.
With the help of the radio telescope located at the Dominion Radio Astrophysical Observatory, operated by the National Research Council of Canada, in British Columbia, Canada, the telescope has nearly quadrupled the number of FRB discovered to date.
Researchers at Michigan Medicine found people with cerebral palsy have fragile bones that present high fracture risk, but at different times across the lifespan compared to the general population. The results helped them develop new sex-specific critical periods of bone health for this population.
It eventually became a Nobel prize-winning revolution when researchers first engineered CRISPR as a gene editing technology for bacterial, plant, animal and human cells.
As more people are taking advantage of music on the go, personal audio systems are pumping up the volume to the detriment of the listener’s hearing. During the 180th ASA Meeting, Daniel Fink from The Quiet Coalition and Jan Mayes will talk about current research into personal audio system usage and the need for public health hearing conservation policies. Their session, “Personal audio system use can harm auditory health,” will take place Thursday, June 10.
A Ludwig Cancer Research study adds to growing evidence that immune cells known as macrophages inhabiting the body cavities that house our vital organs can aid tumor growth by distracting the immune system’s cancer-killing CD8+ T cells.
Reported in the current issue of Cancer Cell and led by Ludwig investigators Taha Merghoub and Jedd Wolchok at Memorial Sloan Kettering (MSK) and Charles Rudin of MSK, the study shows that cavity-resident macrophages express high levels of Tim-4, a receptor for phosphatidylserine (PS), a molecule that they surprisingly found on the surface of highly activated, cytotoxic and proliferative CD8+ T-cells.
A combination of ibrutinib and venetoclax was found to provide lasting disease remission in patients with newly diagnosed chronic lymphocytic leukemia (CLL), according to researchers at The University of Texas MD Anderson Cancer Center. Findings from the single-institution Phase II study were published today in JAMA Oncology and provide the longest follow-up data on patients treated with this drug regimen.
Children with documented child protection concerns are four times as likely to die before they reach their 16th birthday, according to confronting new research from the University of South Australia.
Researchers at UC San Diego, San Diego State University, and international collaborators have designed and validated a prediction model to signal counties at risk of future overdose death outbreaks.
Surgeons can ease their patients’ pain from common operations without prescribing opioids, and avoid the possibility of starting someone on a path to long-term use, a pair of new studies suggests.
Until now, systemic biomarkers to measure exercise effects on brain function and that link to relevant metabolic responses were lacking. A study shows a memory biomarker, myokine Cathepsin B (CTSB), increased in older adults following a 26-week structured aerobic exercise training. The positive association between CTSB and cognition, and the substantial modulation of lipid metabolites implicated in dementia, support the beneficial effects of exercise training on brain function and brain health in asymptomatic individuals at risk for Alzheimer’s.
A major upgrade to the world’s largest outdoor earthquake simulator reached a milestone mid-April when the facility’s floor–all 300,000 lbs of it–was put back into place. When completed this fall, the simulator will have the ability to reproduce multi-dimensional earthquake motions with unprecedented accuracy to make structures and their residents safer during strong shakes. Researchers lay out the details of the upgrade in a paper published recently in Frontiers in Built Environment.
A study published in the June 10, 2021 issue of Cell describes a remarkable new mechanism by which the body’s own immune system can eliminate cancer cells without damaging host cells. The findings have the potential to develop first-in-class medicines that are designed to be selective for cancer cells and non-toxic to normal cells and tissues.
When nature vanishes, people of color and low-income Americans disproportionally lose critical environmental and health benefits–including air quality, crop productivity and disease control–a new study in Nature Communications finds.
The research and innovation building NEST of Empa and Eawag can now be visited virtually at any time and from anywhere in the world. The launch of the virtual NEST tour is a further step towards closing the gap between laboratory research and market entry. By making numerous innovations, developed and demonstrated at NEST, accessible to a much broader and more international audience, the virtual NEST is making a significant contribution to ensuring that sustainable innovations in the building and energy sector can spread faster and thus gain a foothold in the construction industry.
Bacteriophages are still a relatively unknown component of the human microbiome. However, they can play a powerful role in the life cycles of bacteria. Biochemist Thomas Böttcher from the University of Vienna and PhD student Magdalena Jancheva were able to show for the first time how Pseudomonas bacteria use a self-produced signal molecule to selectively manipulate phages in a competing bacterial strain to defeat their enemy. This targeted control of phages provides entirely new biotechnological and therapeutic approaches, e.g. for phage therapies. The results produced in the context of an ERC grant have been published in the “Journal of the American Chemical Society”.
Treating transplant patients with mild to moderate cases of COVID-19 with monoclonal antibodies is safe and helps prevent serious illness, according to a Mayo Clinic study recently published in Open Forum Infectious Diseases. These results are especially important because transplant patients who are infected with COVID-19 have a higher risk of severe illness and death.
Changing your eating habits or altering your circadian clock can impact healthy fat tissue throughout your lifespan, according to a preclinical study published today in Nature by researchers with The University of Texas Health Science Center at Houston (UTHealth).
Results from the multi-cohort Phase I/II ARROW clinical trial, conducted by The University of Texas MD Anderson Cancer Center researchers, showed that a once-daily dose of pralsetinib, a highly selective RET inhibitor, was safe and effective in treating patients with advanced RET fusion-positive non-small cell lung cancer (NSCLC) and RET-altered thyroid cancer.