Using advanced imaging technology, Mayo Clinic scientists have provided an unprecedented understanding of the BRCA1-BARD1 protein complex, which is often mutated in patients with breast or ovarian cancer. Their paper, published in Nature, identifies aspects of how BRCA1-BARD1 functions, supporting future translational research, cancer prevention efforts and drug development.
Mount Sinai researchers have developed a therapeutic agent that shows high effectiveness in vitro at disrupting a biological pathway that helps cancer survive, according to a paper published in Cancer Discovery, a journal of the American Association for Cancer Research, in July.
New York, NY (July 23, 2021) — Mount Sinai researchers have developed a therapeutic agent that shows high effectiveness in vitro at disrupting a biological pathway that helps cancer survive, according to a paper published in Cancer Discovery , a…
A new study by Fergus Couch, Ph.D., of Mayo Clinic Cancer Center, along with collaborators from the CARRIERS consortium, suggests that most women with breast cancer diagnosed over 65 should be offered hereditary cancer genetic testing. The study was published Thursday, July 22, in the Journal of Clinical Oncology.
Tarsha Jones, Ph.D., principal investigator and an assistant professor of nursing at FAU’s Christine E. Lynn College of Nursing, has received the National Institute of Health (NIH) K01 Career Development Award, a five-year, $772,525 award for a project titled, “Decision Support for Multigene Panel Testing and Family Risk Communication among Racially/Ethnically Diverse Young Breast Cancer Survivors.”
Cardiovascular disease and cancer, the nation’s top two killers, share common ground like obesity and chronic inflammation, as well as a disproportionate impact on Black Americans. A new American Heart Association-funded center at the Medical College of Georgia is working…
The UNM Comprehensive Cancer Center helps patients with high-complexity cases. Elyse Eckart’s experience with breast cancer has led her to take on new challenges and embrace tasks and activities she may not have before. She’s also giving back to the community.
List includes potential carcinogens that act by stimulating production of hormones that fuel breast tumors
CHAMPAIGN, Ill. — A new approach to treating breast cancer kills 95-100% of cancer cells in mouse models of human estrogen-receptor-positive breast cancers and their metastases in bone, brain, liver and lungs. The newly developed drug, called ErSO, quickly shrinks…
George Mason faculty Michelle Williams leads program evaluation determining feasibility of See, Test, & Treat Program to addresses barriers and improve health outcomes for cervical, breast, and oral cancer among under-served women in Mississippi
The UC Davis Comprehensive Cancer Center received a $50,000 grant from the Safeway Foundation. The funding will allow researcher Mili Arora to study whether the spice turmeric can provide pain relief for breast cancer patients on oral anti-estrogen drugs.
Return to routine screening for BI-RADS 3 lesions on supplemental automated whole-breast ultrasound substantially reduces the recall rate, while being unlikely to result in adverse outcome
A new paper in the Journal of the National Cancer Institut e, published by Oxford University Press, indicates that disruptions in health care due to the COVID 19 pandemic may increase breast cancer deaths. In March 2020 public health measures…
One in four new breast cancers and one in five colon cancers in Canada attributed to alcohol
Better treatments of HER2-positive breast cancer are closer at hand, thanks to new research by a team led by Université de Montréal professor Jean-François Côté at the cytoskeleton organization and cell-migration research unit of the UdeM-affiliated Montreal Clinical Research Institute.…
The American College of Surgeons (ACS) Surgical Skills Patient Education Program has launched a new kit for breast cancer patients that will help guide them from diagnosis to recovery. The ACS Surgical Skills Patient Education Program provides evidence-based knowledge, checklists, and skills training to support patients with preparation for surgery and optimal recovery.
Department of Radiology Chair Elizabeth Morris, with the UC Davis Comprehensive Cancer Center, was awarded a Susan G. Komen® grant to develop artificial intelligence models to predict breast cancer risk at a more personalized level
UNM Comprehensive Cancer Center conducted a two-pronged study looking into the efficacy of 3D mammograms and also the general awareness of the technology among at-risk populations in New Mexico. The study was conducted prior to the technology gaining more use among the public, and showed fewer callbacks and more awareness even in its early days.
#ASTRO21 will be the first major medical conference in the city; a curated digital program also will be offered for remote attendees
The site of breast cancer metastases dictates their clonal composition and reversible transcriptomic profile
Offers an analytical approach that has no equivalents in the current bioinformatics/systems biology toolbox
CU Department of Surgery’s Victoria Huynh, MD, and Sarah Tevis, MD, are developing new protocols to improve surgical recovery
UC San Diego studies using human cell lines and tumors grown in mice provide early evidence that inhibiting RNA-binding proteins, a previously overlooked family of molecules, might provide a new approach for treating some cancers.
What The Study Did: Changes in the use of women’s preventive health services during the COVID-19 pandemic, including screening for sexually transmitted infections, breast and cervical cancer, and obtaining contraceptives from pharmacies are described by researchers in this study. Authors:…
Fast facts: Nanobodies have been shown to inhibit the dysfunction of key proteins involved with various diseases such as rheumatoid arthritis, osteoarthritis, psoriasis, B-cell lymphoma, and breast cancer Understanding the structure of a nanobody helps to better understand its disease-fighting…
Black women still have twice the rate of breast cancer death than their white counterparts
The article by Dr. Biswa Mohan Sahoo et al. is published in Anti-Cancer Agents in Medicinal Chemistry, 2021
Breast surgeons at Hackensack Meridian Hackensack University Medical Center have a new tool that allows them to pinpoint breast tumors more easily, with many benefits to the patient.
According to a new study, by the Harvey L. Neiman Health Policy Institute and the American College of Radiology’s National Mammography Database Committee, the most influential radiologist characteristics impacting mammography interpretive performance were geography, breast sub-specialization, performance of diagnostic mammography, and performance of diagnostic ultrasound.
Rice University bioengineers collaborated on a six-year study that systematically analyzed how the surface architecture of breast implants influences the development of adverse effects, including an unusual type of lymphoma.
In a new study by researchers at Yale Cancer Center, combining the immunotherapy drug durvalumab and PARP-inhibitor olaparib with chemotherapy improved response to treatment for women with high-risk, HER2-negative breast cancer, including a subset of estrogen receptor positive cancers.
The research utilizes the body’s natural killer cells, part of the human immune system, to target breast cancer tumor cells. The triggers are fusion proteins developed by Clemson University researchers that link the two together. The research is a novel approach to developing breast cancer-specific immunotherapy.
Just a small number of cells found in tumors can enable and recruit other types of cells nearby, allowing the cancer to spread to other parts of the body, report Georgetown Lombardi Comprehensive Cancer Center scientists. Working with their research collaborators, the scientists found that ‘enabler cells’ comprise about 20 percent or less of the cells in an aggressive tumor; their small numbers may account for why they are often missed when bulk tissue analyses are used to inform therapeutic decisions.
Study lays groundwork for possible new immunotherapy for the world’s most commonly diagnosed cancer
Vulnerable population offers keys to better communications on vaccines, researchers argue
The prevalence of genetic mutations associated with breast cancer in Black and white women is the same.
Untangling the proteins that trigger some cancerous tumors
What The Study Did: This survey study among women with breast cancer in Mexico evaluates their specific concerns about and high hesitancy rate toward COVID-19 vaccination. Authors: Cynthia Villarreal-Garza, M.D., D.Sc., of the Breast Cancer Center, Hospital Zambrano Hellion TecSalud…
Researchers at Roswell Park Comprehensive Cancer Center led the largest study to date to suggest an improving trend in pathologic complete response rates over time for U.S. cancer patients of various races. The team’s findings, documented in a poster presentation at the 2021 American Society of Clinical Oncology virtual annual meeting (abstract 575), show that African Americans are more likely than patients from any other group to have remaining disease following breast cancer treatment.
CHAMPAIGN, Ill. — Scientists working to understand the cellular processes linking high cholesterol to breast cancer recurrence and metastasis report that a byproduct of cholesterol metabolism causes some cells to send out cancer-promoting signals to other cells. These signals are…
Two gene variants found in African American women may explain why they are more likely to be diagnosed with triple negative breast cancer (TNBC) than white women of European ancestry, according to Weill Cornell Medicine and NewYork-Presbyterian investigators. The study…
Mount Sinai Health System has recruited an internationally recognized expert in the management of breast cancer and HIV-associated malignancies, Joseph A. Sparano, MD, FACP, as Chief of Hematology and Medical Oncology and Deputy Director of The Tisch Cancer Institute (TCI). Dr. Sparano will also hold the Ezra M. Greenspan, MD Professorship in Clinical Cancer Therapeutics at the Icahn School of Medicine at Mount Sinai and will oversee the expansion of clinical and research capacities of the Division and TCI.
Queen Sirikit Center for Breast Cancer, King Chulalongkorn Memorial Hospital, Thai Red Cross Society (Chulalongkorn Hospital) has become the world’s first institution to have successfully used immunotherapy to treat a breast cancer patient who is now in complete remission with minimal side effects and uplifted quality of life.
A new study of more than 350,000 women found that women with diets incorporating more foods that increase inflammation in the body had a 12% increase in their risk of breast cancer compared to women who consume more anti-inflammatory diets.
‘Hepatocellular carcinoma (HCC) is the third leading cause of cancer related death worldwide, with a poor median survival time after diagnosis of six months’
Reporting at the 2021 annual meeting of the American Society of Clinical Oncology, Kathryn A. Gold, MD, associate clinical professor at University of California San Diego School of Medicine, presented data showing a decrease in people diagnosed with early stage…
Results were released this week on a new treatment with the potential to improve the outcomes for patients with hereditary BRCA mutations and high-risk, early-stage breast cancer. These results represent the first time a drug that blocks cancer cells from repairing their DNA (called a PARP inhibitor) has been shown to significantly reduce the risk of breast cancer returning in high-risk patients following completion of standard chemotherapy, surgery and radiation therapy.
Interdisciplinary team finds combining certain data after a patient’s first treatment can predict how a tumor will respond to chemotherapy.
New research shows that diet, including fish oil supplements, can alter not only the breast microbiome, but also breast cancer tumors. The study appears online in Cancer Research, a journal of the American Association for Cancer Research.
National survey finds oncologists underestimate patient use of complementary and lifestyle therapies