MD Anderson Research Highlights for October 4, 2023

The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back. Recent developments at MD Anderson include a computer game that helps breast cancer survivors improve symptoms of peripheral neuropathy, a publicly available single-cell atlas of CD19 chimeric antigen receptor (CAR) T cells, new targets for TP53-mutant acute myeloid leukemia (AML), a preclinical target for preventing chemobrain, a blood test to help identify patients at higher risk of developing pancreatic cancer, and genomic insights to predict the risk of outcomes in patients with bone cancer.

Chula Medicine Reveals Innovative Detection of Latent Dementia A 10-Year Awareness May delay Alzheimer’s Onset in Elderly

Thai Red Cross Emerging Infectious Diseases Health Science Center, Faculty of Medicine, Chulalongkorn University has researched a blood test for markers of Alzheimer’s that can give a 10-year warning, so people can be prepared to slow down the development of dementia in old age.

New blood test can detect ‘toxic’ protein years before Alzheimer’s symptoms emerge, study shows

Researchers can detect small “toxic” aggregates of a particular protein in the blood of individuals with Alzheimer’s disease and in individuals who showed no signs of cognitive impairment at the time the blood sample was taken, but who developed it at a later date.

New Data Shows 85% Reduction in One-Year Mortality for Medicare Heart Failure Patients With BVA-Guided Care

New data validate the benefits of the BVA-100 blood volume measurement test for Medicare heart failure patients. Data were presented at the Heart Failure Society of America (HFSA) Annual Scientific Meeting (ASM) 2022 – which brought together the world’s leading experts in heart failure.

A shortage with a silver lining: A chance to reduce unneeded blood tests

A pandemic-related shortage of a mundane item – tubes to collect blood samples from patients — has caused headaches for health systems worldwide. But it may also have a silver lining: A lesson in how to reduce unneeded medical tests, whether or not there’s a shortage, according to a new study.

NUS researchers develop world’s first blood test for real-time monitoring of cancer treatment success

A team of researchers from the NUS Department of Biomedical Engineering and Institute for Health Innovation & Technology has developed a novel blood test called ExoSCOPE that could tell doctors whether cancer treatment is working for a patient, within 24 hours after the treatment. This will enable doctors to customise the treatment plan to improve patients’ chances of recovery.

Immunomics: A Conversation on the Future of Diagnostics with Ramy Arnaout

In a recent perspective article, pathologists outline how the immunome — all of the genes collectively expressed by an individual’s immune cells — holds the potential to provide researchers and physicians with unprecedented insight into an individual’s health. Collecting that information from large numbers of patients could one day facilitate diagnostics via a near-universal blood test and pave the way to targeted therapies for a wide variety of conditions.

Rapid blood test identifies COVID-19 patients at high risk of severe disease

Scientists at Washington University School of Medicine in St. Louis have shown that a relatively simple and rapid blood test can predict which patients with COVID-19 are at highest risk of severe complications or death. The blood test measures levels of mitochondrial DNA, which normally resides inside the energy factories of cells. Mitochondrial DNA spilling out of cells and into the bloodstream is a sign that a particular type of violent cell death is taking place in the body.

New experimental blood test determines which pancreatic cancers will respond to treatment

GRAND RAPIDS, Mich. (Oct. 22, 2020) — Scientists have developed a simple, experimental blood test that distinguishes pancreatic cancers that respond to treatment from those that do not. This critical distinction could one day guide therapeutic decisions and spare patients with resistant cancers from undergoing unnecessary treatments with challenging side effects.

Researchers make significant step toward blood test for Alzheimer’s disease

Researchers at Washington University School of Medicine in St. Louis have developed a technique to detect minute amounts of a protein fragment linked to Alzheimer’s disease in the blood. The study, which will be published July 28 in the Journal of Experimental Medicine (JEM), shows that levels of p-tau-217 are elevated during the early stages of Alzheimer’s disease and could lead to a simple blood test capable of diagnosing the neurodegenerative disorder years before any symptoms begin to appear.

Mount Sinai Developing an “End-to-End” Diagnostics Solution for COVID-19 That Incorporates Diagnosis, Treatment Selection, and Monitoring of Disease Course

An expert team of researchers and clinicians have been working together to design, validate, and implement an “end-to-end” clinical pathology laboratory solution that will allow for the testing of approximately several hundred people per day in order to rapidly diagnose and help guide the selection of treatment and monitor disease course.

Carrots plus sticks: Study looks at what works to reduce low-value care

The old story of a farmer trying to get a stubborn mule to pull a wagon by dangling a carrot in front of its nose, or hitting its rump with a stick, may not seem to have much to do with the practice of medicine. But a new study suggests that when it comes to making the best use of health care dollars, it will take a combination of carrots and sticks to move things forward.

Blood Test Predicts Stroke Risk in Patients with Diabetes

ANN ARBOR, Mich. – Having diabetes is a risk factor for many other health conditions, including stroke. “Every 40 seconds an American has a stroke,” says Frederick Korley, M.D., Ph.D., an assistant professor of emergency medicine at Michigan Medicine. “To be…