Protein Shapes Matter in Alzheimer’s Research

Even small changes may have big, long-term consequences. For amyloid beta peptides, a major hallmark of Alzheimer’s disease, a common chemical modification at a particular location on the molecule has a butterfly effect that leads to protein misfolding, aggregation and cellular toxicity.

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Flickering Light Mobilizes Brain Chemistry That May Fight Alzheimer’s

The promise of flickering light to treat Alzheimer’s takes another step forward in this new study, which reveals stark biochemical mechanisms: The 40 Hertz stimulation triggers a marked release of signaling chemicals.

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Pathogenic Alzheimer’s disease cascade is activated by faulty norepinephrine signaling

Preclinical research has revealed a key missing piece of the Alzheimer’s disease puzzle. That allowed proof-of-concept experiments — using an existing drug — that dramatically reduced Alzheimer’s pathology and symptoms in mouse models, potentially offering an immediate treatment for this disease.

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