UC San Diego scientists will lead several components of Bridge2AI, a new NIH-funded program to promote the use of AI in health and research.
A historically overlooked rod-like projection present on nearly every cell type in the human body may finally be getting its scientific due: A new study has found that these appendages on neurons in the brain have a key role in ensuring a specific dopamine receptor’s signals are properly received.
A research team led by Caltech spent nearly 20 years determining X-ray structures, one by one, to create a map of the nuclear pore complex, one of the largest and most complex pieces of cellular machinery.
Peptyde Bio discovers, designs, and characterizes novel anti-microbial peptides (AMPs)
A Rutgers scientist is part of an international team that has determined the process for incorporating selenium – an essential trace mineral found in soil, water and some foods that increases antioxidant effects in the body – to 25 specialized proteins, a discovery that could help develop new therapies to treat a multitude of diseases from cancer to diabetes.
Programmed cell death is an important tool that an organism uses to keep itself healthy. When a cell does not function as it should, various stress reactions are activated.
Many people may not realize that the humble sea urchin is a titan when it comes to the study of biology. Now, researchers from Japan have discovered that sea urchins could help biological studies go further than ever before.
For the first time, UNC-Chapel Hill scientists have measured the concentration of a biomarker of the commonly used fungicide azoxystrobin in the urine of pregnant women and children. They also documented maternal transfer of the chemical to mouse embryos and weaning-age mice.
A Rutgers researcher will use genomics, genetics, and cell biology to identify and understand the corals’ response to heat stress conditions and to pinpoint master regulatory genes involved in coral bleaching due to global warming and climate change. The researcher and his team will use a novel gene-editing tool as a resource to knock down some gene functions with the goal of boosting the corals’ abilities to survive.
The American Society for Cell Biology (ASCB) welcomes Rebecca Alvania as its new Chief Executive Officer, effective January 3, 2022. Alvania comes to ASCB from the American Society for Microbiology, where she served as the Assistant Director of Journals.
University of California San Diego researchers, with international colleagues, describe how energy expenditure and heat production are regulated in obesity through a previously unknown cellular pathway.
University of California San Diego researchers describe how a pair of fundamental genetic and cellular processes — aneuploidy and unfolded protein response — are exploited by cancer cells to promote tumor survival and growth.
UC San Diego School of Medicine researchers will receive $6.4 million in National Institutes of Health grant funding to study how external signals and genetic variations influence the behavior of one cell type in particular: insulin-producing beta cells in the pancreas.
Tessa Burch-Smith, PhD, has joined the Danforth Center as Associate Member and Principal Investigator. Her research is focused on how plant cells communicate with each other through intercellular pores called plasmodesmata.
The following people were recognized by either receiving an honorific award and/or being invited to present a keynote speech or lecture. Congratulations to all. ASCB will feature longer profiles of some of these award winners on its website and in its newsletter in the coming months.
The American Society for Cell Biology (ASCB) is pleased to present its cohort of 14 new Fellows for 2021.
Lab studies reveal protein HSP27’s role in blood vessel leakage, opening the possibility that therapeutically dialing its activity up or down might stabilize patients with sepsis.
Genes can be expressed in different ways depending on how cells process their messengers, aka splicing isoforms. Genetic mutations can damage some splicing isoforms but not others. UC San Diego School of Medicine researchers found that splicing isoforms hit by…
Stem cell models derived from people with specific genomic variation recapitulate aspects of their autism spectrum disorder, providing a valuable model to study the condition and look for therapeutic interventions.
UC San Diego researchers detail how a ubiquitous signaling molecule plays a critical role in male fertility, orchestrating key steps that promote sperm motility, survival and fertilization success.
UC San Diego researchers develop a method to grow hematopoietic stem cells in culture, with clinical implications for bone marrow transplants and aging research.
Nanocontainers can transport substances into cells where they can then take effect.
Many disease-causing bacteria such as Pseudomonas aeruginosa crawl on surfaces through a walk-like motility known as “twitching”. Nanometers-wide filaments called type IV pili are known to power twitching, but scientists ignore which sensory signals coordinate the microbes’ movements. Now, EPFL…
‘Refolding’ molecules to support medical solutions
Almost all crop plants form associations with a particular type of fungi – called arbuscular mycorrhiza fungi – in the soil, which greatly expand their root surface area. This mutually beneficial interaction boosts the plant’s ability to take up nutrients…
People who develop severe COVID-19 have markedly blunted antiviral responses in the nasopharynx
Findings highlight pathway to remove unstable cells
Cells sampled at the time of diagnosis from patients who later developed severe COVID-19 show a muted antiviral response, study finds
Advances in microscopy have enabled researchers to picture loops of DNA strands for the first time.
Over the last few decades, neurodegenerative diseases became one of the top 10 global causes of death. Researchers worldwide are making a strong effort to understand neurodegenerative diseases pathogenesis, which is essential to develop efficient treatments against these incurable diseases.…
Known and yet unexpected: many active substances influence the cholesterol homeostasis and thereby possibly a SARS-CoV-2 infection
Researchers from Osaka University uncover a mechanism by which chromosomal rearrangements occur, with implications for novel cancer therapies
Glutamate and GABA in the brain have reverse relationships with math ability, which switch during development
Rice, Baylor labs use custom hydrogels to mimic insides of intestines, study infectious bacteria
Some antibiotics appear to be effective against a form of skin cancer known as melanoma. Researchers at KU Leuven, Belgium, examined the effect of these antibiotics on patient-derived tumours in mice. Their findings were published in the Journal of Experimental…
Researchers find pre-transplant cardiovascular diseases indirectly affect mortality and survival through increased post-transplant disease occurrence
A research team led by Dr Aixin YAN, Associate Professor from the Research Division for Molecular & Cell Biology, Faculty of Science, in collaboration with Honorary Clinical Professor Patrick CY WOO from the Department of Microbiology, Li Ka Shing Faculty…
Transcription generates a force that moves across DNA strands like ripples through water
ITHACA, N.Y. – A new method that analyzes how individual immune cells react to the bacteria that cause tuberculosis could pave the way for new vaccine strategies against this deadly disease, and provide insights into fighting other infectious diseases around…
Replication of SARS-CoV-2, the virus responsible for COVID-19, depends on a series of interactions between viral proteins and different cellular partners such as nucleic acids (DNA or RNA). Characterizing these interactions is crucial to elucidate the process of viral replication…
SARS-CoV-2 still poses major challenges to mankind. The frequent emergence of mutant forms makes the threat posed by the virus difficult to predict.
Researchers at Weill Cornell Medicine and NewYork-Presbyterian in New York have discovered that injecting mice with pulmonary endothelial cells–the cells that line the walls of blood vessels in the lung–can reverse the symptoms of emphysema. The study, which will be…
Study in budding yeast brings molecular biology to climate change
Although Enterococcus faecalis is usually an innocuous member of the bacterial community in the human gut, it can also cause several infections, including liver disorders. The bacteria produce cytolysins, which are molecules that destroy cells. In a new study, researchers…
Drugs must be safe not just for the patients; in the case of pregnant patients, drugs must also be safe for the unborn children still in the womb. Therefore, at an early stage in the development of new medicines, candidate…
Alexandria, Va., USA – The International Association for Dental Research (IADR) announced Alastair Sloan, The University of Melbourne, Australia, as the 2021 recipient of the IADR Isaac Schour Memorial Award. Sloan was recognized during the Opening Ceremonies of the virtual…
New Rochelle, NY, July 21, 2021– Evaluating the efficacy of novel therapies requires the ability to monitor wound progression accurately and reproducibly over time. Researchers have proposed a new scoring system for wound healing in mice based on parameters in…
HSE researchers uncover the fundamental mechanisms behind the maturation of microRNA molecules
Researchers at the RIKEN Center for Biosystems Dynamics Research (BDR) have succeeded in creating the first genetically engineered marsupial. This study, published in the scientific journal Current Biology , will contribute to deciphering the genetic background of unique characteristics observed…
CHAMPAIGN, Ill. — A new approach to treating breast cancer kills 95-100% of cancer cells in mouse models of human estrogen-receptor-positive breast cancers and their metastases in bone, brain, liver and lungs. The newly developed drug, called ErSO, quickly shrinks…