English
Arabic
Chinese (Simplified)
Dutch
Esperanto
French
German
Greek
Italian
Japanese
Korean
Portuguese
Russian
Spanish
UrduA first-of-its-kind study identifies mechanisms that explain how a drug commonly used to treat HIV and hepatitis causes kidney disease and kidney injury. The study is published ahead of print in Function.
Tag: Kidney Disease
UC San Diego Health Named Center of Excellence for Polycystic Kidney Disease
UC San Diego Health has been named a Center of Excellence for polycystic kidney disease (PKD) by the PKD Foundation – the leading advocacy group dedicated to finding treatments and a cure for PKD. UC San Diego Health is one of just 28 institutions nationwide to receive this designation.
Staph infection-induced kidney disease may be linked to bacterial gene mutation
Researchers aiming to predict which staph-infection patients might develop a related kidney disease have found a high frequency of gene mutations in the infecting bacteria of affected patients, which suggests these variants may play a role in the body’s initiation of the renal damage.
Published Real World Evidence Demonstrates KidneyIntelX™ Improved Clinical Decisions and Outcomes in High-Risk Patients with Early-Stage Diabetic Kidney Disease
Renalytix plc (NASDAQ: RNLX) (LSE: RENX) announces the publication of new real-world evidence (RWE) in Primary Care and Community Health demonstrating the Company’s KidneyIntelX bioprognostic™ test resulted in changed clinical decision making for patients in the early-stage of diabetic kidney disease (DKD) being cared for within the Mount Sinai Health System’s Population Health Ambulatory Pharmacy and Condition Management programs.
Podocyte Protectors: NIH Awards CHLA’s GOFARR Laboratory Additional Grants to Combat Chronic Childhood Kidney Disease
CHLA has received a new five-year award of $3.2 million from the National Institutes of Health (NIH) to research the underlying mechanisms that lead to kidney failure and to develop new treatments to protect kidney function.
Researchers Identify Potential New Therapeutic Target for Polycystic Kidney Disease
Article title: The lonidamine derivative H2-gamendazole reduces cyst formation in polycystic kidney disease Authors: Shirin V. Sundar, Julie Xia Zhou, Brenda S. Magenheimer, Gail A. Reif, Darren P. Wallace, Gunda I. Georg, Sudhakar R. Jakkaraj, Joseph S. Tash, Alan S.L.…
New Risk Score Predicts Mortality for Atrial Fibrillation Patients Undergoing Transcatheter Aortic Valve Replacement
Mount Sinai researchers develop new risk stratification tool to optimize patient care and outcomes after TAVR
CHOP and Penn Launch Kidney Innovation Center to Accelerate Discovery and Improve Treatment of Kidney Disease Across the Lifespan
In an effort to improve the lives of children and adults with kidney disease, Children’s Hospital of Philadelphia (CHOP) and Penn Medicine are jointly launching the Penn-CHOP Kidney Innovation Center. The first-of-its-kind center will advance research to transform patient care for those of all ages, focusing on the early detection, prevention, and treatment of kidney disease and its complications.
Albupro Plus Dietary Supplements Research from Chula for Kidney Patients and all Healthy People
A lecturer of the Faculty of Allied Health Sciences, Chula unveils her research on high egg white protein dietary supplement Albupro Plus, functional food for health lovers, now ready for sale.
Study shows HIV speeds up body’s aging processes soon after infection
HIV has an “early and substantial” impact on aging in infected people, accelerating biological changes in the body associated with normal aging within just two to three years of infection.
Vitamin D Supplements May Offset Bone Loss Caused by Diabetes Drug
Vitamin D supplementation may help offset damaging bone loss that occurs in some people who take canagliflozin, a commonly prescribed diabetes drug. Researchers will present their work this week at the American Physiological Society (APS) and American Society for Nephrology Control of Renal Function in Health and Disease conference in Charlottesville, Virginia.
Intermittent Fasting Protects Kidneys of Obese Mice
New research in mice finds that time-restricted feeding improves markers of kidney and vascular health. The research will be presented this week at the American Physiological Society and American Society for Nephrology Control of Renal Function in Health and Disease conference.
Common Prebiotic Fiber Mitigates Harm of High-salt Diet in Rats
New research in rats finds a diet high in the fiber inulin offered a protective effect against the damage of a high-salt diet. The research will be presented this week at the American Physiological Society and American Society for Nephrology Control of Renal Function in Health and Disease conference
Past Kidney Disease May Increase Preeclampsia Risk, Impair Blood Vessel Health during Pregnancy
A history of kidney problems may put people at a higher risk for impaired blood vessel function, which could lead to high blood pressure, preterm labor and other adverse outcomes, according to the results of a study in rats. The researchers will present their work this week at the American Physiological Society (APS) and American Society for Nephrology Control of Renal Function in Health and Disease conference in Charlottesville, Virginia.
The COVID-19 pandemic’s impact on treatment decision-making for older patients with kidney disease
A recent study examined how uncertainty surrounding the evolving COVID-19 pandemic influenced shared decision-making between clinicians, older patients with chronic kidney disease, and their care partners.
Kidney Stone Formation Linked to Polycystic Kidney Disease in Mice
Article title: Kidney stone formation in a novel murine model of polycystic kidney disease Authors: Heather A.L. Riddle, Shiqin Zhang, Feng Qian, James C. Williams Jr., Jason R. Stubbs, Peter Stanley N. Rowe, Stephen C. Parnell From the authors: “Our…
New Liver and Kidney Disease Identified
Scientists have identified a new disease in a ground-breaking discovery that could help patients with unexplained liver and kidney problems.
Calorie Count More Important than Nutrient Composition in Development of Obesity-related Kidney Disease
Article title: High-calorie diet results in reversible obesity-related glomerulopathy in adult zebrafish regardless of dietary fat Authors: Evan M. Zeitler, J. Charles Jennette, Jennifer E. Flythe, Ronald J. Falk, John S. Poulton From the authors: “This work suggests that macronutrient…
Virtual Population Model Predicts and Stops Kidney Damage in Black Americans
Researchers have successfully used a virtual population to replicate a clinical trial that examined kidney damage in Black Americans, according to a new study at the University of Mississippi Medical Center in Jackson.
Chronic Kidney Disease is Curable if Detected Early – Chula’s User-friendly CKD Screening Strips with Results in 15 minutes!
A Chula research team has developed a screening strip kit to detect the early stage of chronic kidney disease (CKD) that’s easy to use, yields quick results, increasing the chance of being cured for patients, and helping to cut over 10 billion baht of the ever-increasing annual healthcare costs for CKD patients. The CKD screening strip kits are expected to be released early next year.
Researchers ID Protein Complex That Plays Important Role in Kidneys’ Water Balance Pathways
Article title: Actin-related protein 2/3 complex plays a critical role in the aquaporin-2 exocytotic pathway Authors: Chen-Chung Steven Liu, Pui Wen Cheung, Anupama Dinesh, Noah Baylor, Theodor C. Paunescu, Anil V. Nair, Richard Bouley, Dennis Brown From the authors: “In…
Update: Reassessing Inclusion of Race in Diagnosing Kidney Diseases
The National Kidney Foundation (NKF) and the American Society of Nephrology (ASN) congratulate the NKF-ASN Task Force on Reassessing the Inclusion of Race in Diagnosing Kidney Diseases for submitting its final report for publication.
Weight Fluctuations May Predict Poor Outcomes in Adults with Kidney Disease
• In individuals with kidney disease, those with high body mass index variability faced higher risks of needing kidney replacement therapy, experiencing a heart attack, experiencing a stroke, and dying prematurely.
Dapagliflozin Found Effective and Safe in Adults with Advanced Kidney Disease
• The sodium-glucose co-transporter 2 inhibitor dapagliflozin reduced kidney, cardiovascular, and mortality risks in patients with advanced chronic kidney disease, similar to benefits seen in individuals with normal or moderately impaired kidney function.
• Rates of serious side effects were similar in patients with advanced chronic kidney disease who received dapagliflozin or placebo.
For People with Kidney Disease, There Is No Safe Amount of Lead in Drinking Water
• In this analysis of U.S. adults with advanced kidney disease, even low levels of lead in community drinking water had a negative effect on health.
• Higher lead levels were found in the drinking water of predominantly Black communities compared with predominantly white communities.
Patients with Kidney Disease—Even without Anemia—May Benefit From Iron Treatment
• Among individuals with chronic kidney disease, iron deficiency was linked with higher risks of death and cardiovascular events, in patients with and without anemia.
• Clinical trials are needed to test the effects of iron treatment, even in the absence of anemia, in patients with chronic kidney disease.
Precision medicine helps identify “at-risk rapid decliners” in early-stage kidney disease
A novel therapeutic may halt rapid kidney function in some type 1 diabetic kidney disease patients.
Wayne State University and Henry Ford Health System announce new initiative in cardiometabolic health and disease
Wayne State University and Henry Ford Health System announced today the launch of a basic and translational research initiative in Cardiometabolic Health and Disease as a thematic focus for program growth.
Improving dialysis through design
Faculty from the McKelvey School of Engineering and the School of Medicine teamed up to design better grafts for dialysis patients.
ATRIUM HEALTH, WAKE FOREST BAPTIST HEALTH, WAKE FOREST SCHOOL OF MEDICINE AND RENALYTIX PARTNER TO ADVANCE KIDNEY HEALTH
Renalytix AI plc, Atrium Health, Wake Forest Baptist Health and Wake Forest School of Medicine announced a partnership to implement an advanced clinical care model designed to improve kidney health and reduce kidney disease progression and kidney failure in high-risk populations.
Academy of Nutrition and Dietetics Urges Swift Passage of Bill That Would Increase Access to Nutrition Care
The Academy of Nutrition and Dietetics supports expanding medical nutrition therapy to provide Medicare beneficiaries with the care they need and deserve to live healthy, independent lives.
UNH Research: More Than One Way for Animals to Survive Climate Change
Researchers at the University of New Hampshire found that to live in hotter more desert-like surroundings, and exist without water, there is more than one genetic mechanism allowing animals to adapt. This is important not only for their survival but may also provide important biomedical groundwork to develop gene therapies to treat human dehydration related illnesses, like kidney disease.
Surprise Discovery Shows Chronic Heart Dysfunction Protects against Acute Kidney Injury
Article title: Activation of hypoxia-sensing pathways promotes renal ischemic preconditioning following myocardial infarction Authors: Andrew S. Terker, Kensuke Sasaki, Juan Pablo Arroyo, Aolei Niu, Suwan Wang, Xiaofeng Fan, Yahua Zhang, Sochinwechi Nwosisi, Ming-Zhi Zhang, Raymond C. Harris From the authors:…
Study Explores Effects of Exercise on Heart, Lung and Metabolic Physiology during Dialysis
Article title: Cardiopulmonary and metabolic physiology during hemodialysis and inter-/intra-dialytic exercise Authors: Scott McGuire, Elizabeth Jane Horton, Derek Renshaw, Klaris Chan, Nithya Krishnan, Gordon McGregor From the authors: “This study is the first to directly compare cardiopulmonary and metabolic physiology during…
Newly Identified Pathway, Biomarkers May Be Tools to Prevent Kidney Injury-induced Lung Damage
Article title: Altered lung metabolism and mitochondrial DAMPs in lung injury due to acute kidney injury Authors: Mark Hepokoski, Jing Wang, Kefeng Li, Ying Li, Purva Gupta, Tina Mai, Alex Moshensky, Mona Alotaibi, Laura E. Crotty Alexander, Atul Malhotra, Prabhleen Singh…
New App Helps Prevent Medication Harm and Improve Safety in Patients with Kidney Disease
• A one-year trial found that the eKidneyCare smartphone app helped patients with chronic kidney disease take their prescribed medications properly.
• The app may help to prevent adverse drug reactions and other medication errors that can endanger patients.
You are not a cat, but a cat could someday help treat your chronic kidney disease
The Wake Forest Institute for Regenerative Medicine is investigating how cats with chronic kidney disease could someday help inform treatment for humans.
Risk for chronic kidney disease even more critical due to COVID-19 pandemic
An estimated 1 in 10 people worldwide have chronic kidney disease, but most of them don’t know it. That lack of awareness is especially concerning because people with Chronic kidney disease who are infected with COVID-19 are at higher risk for serious illness.
Nicotine Damages Kidney Filters in Smokers with Diabetes
Article title: Nicotine, smoking, podocytes and diabetic nephropathy Authors: Edgar A. Jaimes, Ming-Sheng Zhou, Mohammed Siddiqui, Gabriel Rezonzew, Runxia Tian, Surya V. Seshan, Alecia N Muwonge, Nicholas J. Wong, Evren U. Azeloglu, Alessia Fornoni, Sandra Merscher, Leopoldo Raij From the authors:…
Shift Work Disrupts Kidney Rhythms, Contributes to Kidney and Heart Disease
Article title: Environmental circadian disruption suppresses rhythms in kidney function and accelerates excretion of renal injury markers in urine of male hypertensive rats Authors: Atlantis M. Hill, G. Ryan Crislip, Adam Stowie, Ivory Ellis, Anne Ramsey, Oscar Castanon-Cervantes, Michelle L.…
The University of Utah and RenalytixAI Partner to drive innovation in kidney health
An artificial intelligence-enabled in vitro diagnostics company and the University of Utah today announced a partnership to improve kidney health and reduce the risk of kidney failure for large scale populations in the earliest stages of kidney disease.
New Blood Pressure-Lowering Guidelines Could Benefit 25 Million Americans with Chronic Kidney Disease
A recommendation for more intensive blood pressure management from an influential global nonprofit that publishes clinical practice guidelines in kidney disease could, if followed, benefit nearly 25 million Americans.
Air Pollution Linked to Higher Rates of Kidney Disease
• Exposure to higher amounts of fine particulate air pollution was associated with a greater likelihood of having chronic kidney disease.
• This link was stronger in urban areas, males, younger adults, and adults without comorbid diseases.
Rethinking Race and Kidney Function
Removing race from clinical tools that calculate kidney function could have both advantages and disadvantages for Black patients.
Newly diagnosed patients and those whose kidney disease is reclassified as more severe would have greater access to kidney specialists, faster access to the kidney-transplant waitlist.
On the flipside, patients reclassified as having more severe kidney disease may become ineligible for heart, diabetes, pain control and cancer medications or may be given lower doses for these drugs.
A new kidney function score would also increase the number of Black individuals ineligible to donate a kidney, potentially exacerbating organ shortages for Black people.
Researchers caution that clinicians and policy makers must anticipate both the benefits and downsides of changes to the current formula to ensure that Black patients are not disadvantaged, and
health disparities are not exacerbated.
Scientists say the analysis should motivate researchers and cl
Diabetes Drug Has Kidney-Protective Effects in Patients with Advanced Kidney Disease
• The diabetes drug canagliflozin slowed kidney function decline in patients with diabetes and advanced chronic kidney disease.
• The drug also reduced the risk of developing kidney failure and cardiovascular problems in these patients.
Simultaneous kidney transplant plus weight loss surgery safe for obese patients
A new study shows that robotic-assisted kidney transplant and weight loss surgery can be performed safely.
Research Team Discovers the Molecular Processes in Kidney Cells That Attract and Feed COVID-19
What about the kidneys make them a hotspot for COVID-19’s cytokine storm? A research team says it’s the presence of a protein found on specialized renal transport cells.
Clinical trial shows experimental drug safely slows progression of diabetic kidney disease
Patients with diabetic kidney disease can potentially be treated with a new investigational medication that may slow the progress of their illness without harmful side effects to their hearts, according to the results of a global clinical trial announced Friday.
Harrington Discovery Institute Announces Award Recipients in New UK Rare Disease Program
Announcement of the 2021 Harrington UK Rare Disease Scholar Award recipients, their organizations and fields of research:
Pietro Fratta, MD, PhD – University College London
Gene Therapy for Kennedy’s Disease, a rare neuromuscular disease
Angela Russell, DPhil – University of Oxford
New Drugs for the Treatment of Duchenne Muscular Dystrophy
Helen Waller-Evans, DPhil – Cardiff University
Novel Inhibitors to Treat Multiple Lysomal Storage Disorders, causes of widespread organ damage
Wyatt Yue, PhD – University of Oxford
Inhibitors of Primary Hyperoxaluria, a cause of kidney failure
Haiyan Zhou, MD, PhD – University College London
Novel Therapy for SPTLC1-Related Hereditary Sensory Neuropathy, a cause of shooting pain
Researchers Improve the Standard Method for Assessing Cardiovascular Disease Risk
Taking into account two common kidney disease tests may greatly enhance doctors’ abilities to estimate patients’ cardiovascular disease risks.