Researchers reporting in ACS’ Journal of Agricultural and Food Chemistry have found that levels of volatile, sulfurous compounds are similar in parent-child pairs, suggesting shared oral microbiomes. They also found that high levels cause children to dislike the vegetables.
A study recently published in Nature Communications suggests that displacing cold-water communities of algae with warm-adapted ones threatens to destabilize the delicate marine food web. The team was led by University of East Anglia researchers and included DOE Joint Genome Institute researchers.
A significant indicator of whether a patient with rheumatoid arthritis will improve over the course of disease may lie in part in their gut, according to new research from Mayo Clinic’s Center for Individualized Medicine.
The study, published in Genome Medicine, found that predicting a patient’s future rheumatoid arthritis prognosis could be possible by zeroing in on the trillions of bacteria, viruses and fungi that inhabit their gastrointestinal tract, known as the gut microbiome. The findings suggest that gut microbes and a patient’s outcome of rheumatoid arthritis are connected.
MD Anderson and SNIPR BIOME have announced a strategic collaboration to advance next-generation CRISPR-based microbiome therapies to reduce immune-related side effects in patients treated with immune checkpoint inhibitors.
UC San Diego School of Medicine receives $6.1M to launch a new research center studying the effects of maternal antibiotic use on breast milk and infant health. The center is funded by National Institutes of Health, as part of their new Maternal and Pediatric Precision in Therapeutics (MPRINT) Hub.
The gut microbiome can impact us in a variety of different ways, from our metabolism to our mood. Now, NIBIB-funded researchers are investigating if a fiber-based gel can restore beneficial microbes in the gut to enhance the efficacy of immune checkpoint inhibitors, a type of cancer immunotherapy treatment, in mice.
Beneficial bacteria in the gut microbiome use different means to transmit from one person to another which impacts their abundance in the gut and the functions they provide, new research has found.
Bacteria’s role in gut health has received a lot of attention in recent years. But new research publishing in Nature shows that fungi—another microorganism that lives within us—may be equally important in health and disease. Fungi thrive in the healthy gut, but when interactions with the immune system are off-balance, they cause intestinal damage that may contribute to gastrointestinal disease. Additional investigation demonstrate that vaccines could be developed as therapeutics to improve gut health.
Antibiotic exposure early in life could alter human brain development in areas responsible for cognitive and emotional functions, according to a Rutgers researcher.
Researchers from The University of Texas MD Anderson Cancer Center found specific intestinal microbiota signatures correlate with high-grade adverse events and response to combined CTLA-4 and PD-1 blockade treatment.
A new grant will help Iowa State University researchers figure out how the microbiome, or all the microorganisms that live inside and on human systems, affects immunity and the effectiveness of vaccines. Not everyone responds to vaccines in identical ways, and the researchers will search for ways humans can adjust their microbiomes to optimize vaccine response.
New findings from Cleveland Clinic researchers show for the first time that the gut microbiome impacts stroke severity and functional impairment following stroke. The results, published in Cell Host & Microbe, lay the groundwork for potential new interventions to help treat or prevent stroke. The research was led by Weifei Zhu, Ph.D., and Stanley Hazen, M.D., Ph.D., of Cleveland Clinic’s Lerner Research Institute.
UC San Diego School of Medicine researchers discovered that SARS-CoV-2, or at least its genetic signature, abounds on hospital surfaces, often co-locating with one particular type of bacteria.
A new study at the University of Chicago has determined that restoring a single microbial species — Bacteroides sp. CL1-UC (Bc) — to the gut microbiome at a key developmental timepoint can prevent antibiotic-induced colitis in a mouse model of the condition.
New research shows that diet, including fish oil supplements, can alter not only the breast microbiome, but also breast cancer tumors. The study appears online in Cancer Research, a journal of the American Association for Cancer Research.
Three projects from Philadelphia will become part of the first-ever private mission to the International Space Station
Each city has its own unique microbiome, a “fingerprint” of viruses and bacteria that uniquely identify it, according to a new study from an international consortium of researchers that included a team from the University of Maryland School of Medicine (UMSOM). The international project, which sequenced and analyzed samples collected from public transit systems and hospitals in 60 cities around the world, was published today in the journal Cell.
The diverse collection of microbes known as protists are understudied, but their impact on ecosystems and agriculture could be huge.
Reporters and bloggers are invited to join top nutrition researchers and practitioners for a dynamic virtual program at NUTRITION 2021 LIVE ONLINE. The flagship meeting of the American Society for Nutrition runs June 7–10, 2021 and features research announcements, expert discussions and more.
Researchers examined prenatal stool (meconium) samples collected from 20 babies during breech Cesarean delivery. By including only breech caesarean deliveries in healthy pregnant women they were able to avoid the transmission of bacteria that occurs naturally during a vaginal birth.
Research on biomarkers, carcinogenesis, regulatory science, and more is available in the latest issue of Toxicological Sciences.
Hertz Fellow Ravi Sheth was awarded the 2020 Hertz Thesis Prize for developing new tools used in microbial research.
The University of Chicago Medicine is launching an innovative center that will research how infant health can impact an individuals’ health throughout their lifetime.
Wildfires affect both the visible parts of plants and the plant microbiome. Understanding these effects helps scientists mitigate the effects of wildfires. This research examined microbial DNA samples from tissues of young quaking aspen saplings after a prescribed burn. Aspen relies largely on fire to regenerate. This work demonstrates that fire affects the entire plant microbiome, not just nearby soil.
Exposure to soil microorganisms, human health closely related
MEDIA ADVISORY – UNDER EMBARGO UNTIL Monday, April 5 at 11:00 AM EST Journal Name: Nature Methods Title of the Article: Discovering multiple types of DNA methylation from individual bacteria and microbiome using nanopore sequencing Corresponding Author: Gang Fang, PhD…
The Weizmann Institute’s Prof. Yardena Samuels, Prof. Eran Segal, and Dr. Ravid Straussman, with partners at MD Anderson Cancer Center, the NCI, and elsewhere, have discovered that the bacteria living inside cancer cells can be harnessed to provoke an immune reaction against the tumor. The work could also help explain findings showing that the microbiome affects the success of immunotherapy.
Research on the relationship between the gut microbiome and diet can provide insights into diseases like depression and other health conditions.
These news briefs cover topics including gut microbes, tsetse flies in 3D, an energy use framework for heating and cooling, and new gravitational lensing candidates.
GRAND RAPIDS, Mich. (Feb. 2, 2021) — What does bile acid production in the digestive tract have to do with Parkinson’s disease?
Sediments on the ocean floor contain large amounts of methane. Two groups of microbes work together in symbiosis to break down this methane in oxygen-deprived sediments. New research shows that both groups can fix nitrogen to satisfy their need for nutrients from methane. This helps the microbes hedge against changes in their environment.
A new study out of the University of Chicago and Stanford University on pairs of twins with and without food allergies has identified potential microbial players in this condition.
Chemicals used for vaping break down zipper-like junctions between cells in the gut, leading to chronic inflammation and potential for other health concerns.
Antibiotics for cesarean section births are just as effective when they’re given after the umbilical cord is clamped as before clamping – the current practice – and could benefit newborns’ developing microbiomes, according to Rutgers co-authored research. The study, by far the largest of its kind and published in the journal Antimicrobial Resistance & Infection Control, challenges current recommendations for antibiotic use. Administering antibiotics after clamping does not increase the risk of infection at the site of C-section incisions, the study concludes.
A new study out of UChicago and the Marine Biological Laboratory used state-of-the-art sequencing technology to deep-screen the genomes of microbes known as TM7 present in the mouth. This approach determined that TM7 species living on the tongue more closely resembled those found in the GI tract, while TM7 species in dental plaque more closely resembled environmental species, providing a hint at how plaque may have played a role in microbial colonization of the body.
The bacteria, yeast and viruses that make up the human microbiome affect physical health, behavior and emotions. Some microbes in the human microbiome prosper when the body is under stress, while other microbes contribute to buffering the body against stress. Evolutionary theory suggests reciprocal relationships between microbes in the human body and stress; these relationships can possibly be harnessed to promote physical and mental health.
An enzyme in the colon lining releases hydrogen peroxide – a known disinfecting compound- to protect the body from gut microbial communities. Findings from the UC Davis Health study points to importance of considering a different approach to treating gut inflammation and bacterial imbalance in the colon.
Two Pacific Northwest National Laboratory researchers, one a world-leading authority on microorganisms and their impact on soil and human health, and the other an expert on coastal ecosystem restoration, have been elected fellows of the American Association for the Advancement of Science.
ORNL’s Paul Kent, Dr. Bart Iddins and two teams were recognized for leadership and accomplishment in science, technology and mission support.
Hertz Fellow Cheri Ackerman, Cofounder and CEO of Concerto Biosciences, has received the Hertz Foundation’s Harold Newman and David Galas Entrepreneurial Initiative Award. She plans to use the $25,000 grant to help her company find solutions for human health and agriculture using unique ensembles of microbes.
Scientists have discovered how a common virus in the human gut infects and takes over bacterial cells – a finding that could be used to control the composition of the gut microbiome, which is important for human health. The Rutgers co-authored research, which could aid efforts to engineer beneficial bacteria that produce medicines and fuels and clean up pollutants, is published in the journal Nature.
Study demonstrates how a subset of common gut bacteria renders mice resistant to viral infections.
Children under age 2 who take antibiotics are at greater risk for childhood-onset asthma, respiratory allergies, eczema, celiac disease, obesity and attention deficit hyperactivity disorder, according to a paper written jointly by Mayo Clinic and Rutgers researchers. While previous studies have looked at the association of antibiotics with single diseases, this is the first to look at the association across many diseases.
Advanced X-ray techniques yield insights into a bacterial enzyme that turns methane gas into liquid fuel, and a genome resource expands known diversity of bacteria and archaea by 44%
Reported in Nature Biotechnology, the known diversity of bacteria and archaea has been expanded by 44% through a publicly available collection of more than 52,000 microbial genomes from environmental samples resulting from a JGI-led collaboration involving more than 200 scientists around the world.
A study of the relationships between cognition and the gut microbiome of captive zebra finches showed that their gut microbiome characteristics were related to performance on a cognitive assay where they learned a novel foraging technique. Researchers also identified potentially critical bacteria that were relatively more abundant in birds that performed better on this assay. This correlation provides some of the first evidence of a relationship between a bird’s gut microbiome and its brain.
Below are summaries of recent Fred Hutch research findings and other news with links for additional background and media contacts.
Liver failure – often due to acetaminophen overdose – is fatal in 80% of cases. The labs of Profs. Ido Amit and Eran Elinav discovered three liver-cell subsets that contribute to disease progression, and found that depleting the microbiome acts on those subsets to reduce liver damage and increase survival rates. The research may lead to treatments for liver failure.
For a honey bee, few things are more important than recognizing your nestmates. Being able to tell a nestmate from an invader could mean the difference between a honey-stocked hive and a long, lean winter. New research from Washington University in St. Louis shows that honey bees rely on chemical cues related to their shared gut microbial communities, instead of genetic relatedness, to identify members of their colony.
Oni Basu, PhD, an assistant professor of genetic medicine at the University of Chicago, has received the prestigious National Institutes of Health (NIH) Director’s New Innovator Award. These awards are given to exceptionally creative scientists proposing high-risk, high-impact research at all career stages.