FSU faculty available for context on latest research into autism spectrum disorder

By: Bill Wellock | Published: April 17, 2024 | 8:30 am | SHARE: April is Autism Acceptance Month, an opportunity to raise public awareness and support for people with autism spectrum disorder (ASD).Florida State University experts work to promote interdisciplinary research that advances our understanding of autism and bridges the gap between scientific knowledge and clinical/educational practice.

Case Western Reserve University School of Medicine launches Institute for Glial Sciences

Case Western Reserve University has established an Institute for Glial Sciences to advance research of glial cells and their critical role in the health and diseases of the nervous systems, including multiple sclerosis, Alzheimer’s, pediatric leukodystrophies, Autism spectrum disorders, Parkinson’s disease and cancer.

Protein p53 regulates learning, memory, sociability in mice

Researchers at the Beckman Institute for Advanced Science and Technology have established the protein p53 as critical for regulating sociability, repetitive behavior, and hippocampus-related learning and memory in mice, illuminating the relationship between the protein-coding gene TP53 and neurodevelopmental and psychiatric disorders.

IU-developed statewide initiative shows primary care clinicians can diagnose autism in young children with high accuracy

A new study led by Indiana University School of Medicine researchers shows primary care clinicians who receive specialized training can make accurate autism diagnoses for over 80 percent of young children referred with developmental delays, providing compelling evidence that community-based models of autism evaluation are a potential solution for improving access to this needed service.

Jumpstarting to Independence: A creative solution to improve equity in Applied Behavior Analysis therapy for children with Autism Spectrum Disorder

Children diagnosed with Autism Spectrum Disorder (ASD) benefit from a type of therapy called Applied Behavior Analysis (ABA). ABA can help patients with common challenges of ASD, such as noise sensitivity, communication, attention and daily activities. ABA therapy is generally delivered in a one-on-one setting — typically in the family home, an ABA therapy center or school – to support children with ASD and help work through challenges.

Brain-Like Organoids Grown in a Dish Provide Window into Autism

Whatever you do, don’t call them “mini-brains,” say University of Utah Health scientists. Regardless, the seed-sized organoids—which are grown in the lab from human cells—contained an array of neural and other cell types found in the cerebral cortex, the outermost layer of the brain involved in language, emotion, reasoning, and other high-level mental processes. They are providing insights into the brain and uncovering differences that may contribute to autism in some people.

Rare Human Gene Variant in ADHD, Autism Exposes Fundamental Sex Differences

Key differences in male and female mice brains provide new insights into how sex determines the mechanisms by which distinct synapses monitor and regulate dopamine signaling. The impact of sex differences is particularly pronounced when the mice express a human genetic variant found in boys with either ADHD or autism. Behavioral generalizations across the sexes may limit diagnosis of mental illness, especially if one sex translates alterations into outward signs such as hyperactivity and aggression vs. more internal manifestations such as learning, memory and mood, even when the same molecular pathology is at work.

Canisius Study Examines Short-term Effects of Covid-19 Stay-at-Home Restrictions on Youth with ASD

Researchers from the Institute for Autism Research (IAR) at Canisius College assessed the potential short-term effects of COVID-19 stay-at-home restrictions on ratings of autism spectrum disorder (ASD) and comorbid symptoms severity and adaptive functioning of 69 youth, ages 8–16 years with ASD (without intellectual disability).

UNC TEACCH Researchers Awarded $9 Million for Study of Suicide Prevention Tailored for Youth on the Autism Spectrum

Brenna Maddox, PhD, assistant professor in the UNC Department of Psychiatry and an implementation scientist for the UNC TEACCH Autism Program, is co-leading a national study funded by a $9-million award from the Patient-Centered Outcomes Research Institute (PCORI) that will compare the effectiveness of two suicide prevention interventions for autistic individuals.

Study Shows Visual Evoked Potential Is a Promising Tool for Translational Research Into Phelan-McDermid Syndrome and Autism Spectrum Disorders

Researchers at the Seaver Autism Center for Research and Treatment at Mount Sinai have identified specific transient visual evoked potential waveform abnormalities in individuals with Phelan-McDermid syndrome (PMS), proving the method to be an effective, noninvasive technique to gather objective data from a range of individuals, including those who are profoundly affected.

FSU experts available to share research insights for Autism Acceptance Month

By: Bill Wellock | Published: March 31, 2021 | 1:55 pm | SHARE: The Autism Society of America celebrates April as Autism Acceptance Month as part of the organization’s efforts to build a better awareness of the signs, symptoms and realities of autism.Autism, or autism spectrum disorder (ASD), refers to a broad range of conditions characterized by challenges with social skills, repetitive behaviors, speech and nonverbal communication.

Guilt by Dissociation: Study Sheds Light on Serotonin in Autism

A study on serotonin, a mood-regulating molecule in the brain that regulates many brain synapses, is helping to unravel the puzzle surrounding its role in autism. The activity and regulation of the serotonin transporter (SERT), protein is critically dependent on a number of other proteins that tell the protein where to locate on nerve cells and how to act. Shifts in the transporter’s activity can significantly impact the ability of serotonin to act in the brain.

Pregnant mother’s immunity tied to behavioral, emotional challenges for kids with autism

Children with autism born to mothers who had immune conditions during their pregnancy are more likely to have behavioral and emotional problems, a UC Davis Health study has found. Offspring sex may also interact with maternal immune conditions to influence outcomes, particularly in terms of a child’s cognition.

Seaver Autism Center For Research and Treatment at Mount Sinai Launches First Drug Trial for ADNP Syndrome

Researchers at the Seaver Autism Center for Research and Treatment at Mount Sinai have started recruiting participants for a new clinical trial to evaluate the safety, tolerability, and efficacy of a low dose of ketamine in children diagnosed with ADNP syndrome (also known as Helsmoortel-VanDerAa syndrome), a rare neurodevelopmental disorder caused by mutations in the activity dependent neuroprotective protein (ADNP) gene.

Scientists uncover new genetic mutations linked to autism spectrum disorder

Scientists at Sanford Burnham Prebys Medical Discovery Institute and Radboud University Medical Center in the Netherlands have identified mutations in a gene called CNOT1 that affect brain development and impair memory and learning. The research, published in The American Journal of Human Genetics, also revealed that CNOT1 interacts with several known autism spectrum disorder (ASD) genes, opening new research avenues for the condition.

Depression symptoms linked to reduced cognitive control in people with autism

Adolescents and young adults with autism spectrum disorder (ASD) and those with typical development show similar proactive cognitive control. However, symptoms of depression in individuals with autism were linked to less proactive control, a UC Davis study found.

U.S. Autism Rates Up 10 Percent in New CDC Report

Researchers at the Johns Hopkins Bloomberg School of Public Health contributed to a new U.S. Centers for Disease Control and Prevention report that finds the prevalence of autism spectrum disorder (ASD) among 11 surveillance sites as 1 in 54 among children aged 8 years in 2016 (or 1.85 percent).

Largest Autism Sequencing Study to Date Identifies 102 Genes Associated With the Condition

In the largest genetic sequencing study of autism spectrum disorder (ASD) to date, researchers have identified 102 genes associated with risk for autism. The study also shows significant progress towards teasing apart the genes associated with ASD from those associated with intellectual disability and developmental delay, conditions which often overlap.

Measuring Mutations in Sperm May Reveal Risk for Autism in Future Children

Spontaneous mutations in male sperm are linked to development of autism spectrum disorder. Researchers have created a way to measure mutations and estimate risk of ASD in future children. If developed into a clinical test, the method could be a useful predictive tool in genetic counseling.

In Some Children with Autism, “Social” and “Visual” Neural Circuits Don’t Quite Connect

Researchers combined eye gaze research with brain scans to discover that in a common subtype of autism, in which ASD toddlers prefer images of geometric shapes over those of children playing, brain areas responsible for vision and attention are not controlled by social brain networks, and so social stimuli are ignored.