Omnitrophota are nano-sized bacteria first discovered 25 years ago. Though common in many environments around the world, until now they’ve been poorly understood. An international research team produced the first large-scale analysis of Omnitrophota genomes, uncovering new details about their biology and behavior. The team’s findings are reported in the March 16 issue of the journal Nature Microbiology.
Tag: Dna Sequencing

Even good gene edits can go bad
A Rice University lab is leading the effort to reveal potential threats to the efficacy and safety of therapies based on CRISPR-Cas9, the Nobel Prize-winning gene editing technique, even when it appears to be working as planned.
Global Experts Introduce Strategic Action Plan to Accelerate Patient Access to Next-Generation DNA Sequencing in Oncology
Value & Outcomes Spotlight, the health economics and outcomes research (HEOR) news magazine of ISPOR—The Professional Society for Health Economics and Outcomes Research, announced the publication of a supplement, “A Plan of Action: Accelerating Patient Access to Next-Generation Sequencing in Oncology.”
Genotyping Reveals Significance of Mesophotic Reefs for Florida Keys’ Coral Recovery
Researchers are the first to compare the genetic structure and genomic diversity of paired shallow and upper mesophotic coral sites in the Northern and Southern Dry Tortugas and the Lower and Upper Florida Keys. Results suggest that while vertical connectivity between paired shallow and mesophotic populations can vary, certain mesophotic coral populations are important for maintaining the long-term survival of this ecologically important coral species throughout the Florida Keys and should be considered in future management strategies.
Leading Scientist Working to Complete the Human Genome to Join UCSC Faculty
Leading scientist known for working to complete the human genome will join UCSC faculty; Karen Miga is a longtime Genomics Institute researcher, recently named “one to watch” by the journal Nature.

Overfishing of Atlantic Cod Likely Did Not Cause Genetic Changes
Overfishing likely did not cause the Atlantic cod, an iconic species, to evolve genetically and mature earlier, according to a study led by Rutgers University and the University of Oslo – the first of its kind – with major implications for ocean conservation.

New sequencing approach finds triple-negative breast cancers continue accumulating genetic changes during tumor growth
A new DNA sequencing approach developed by MD Anderson researchers overcomes technical challenges with earlier techniques to give deeper insights into breast cancer evolution.

Lab shutdowns enable speedier investigation of coral disease
Research labs have shut down around the world due to the COVID-19 pandemic, but that hasn’t stopped scientists from Woods Hole Oceanographic Institution (WHOI) from investigating critical problems in the ocean.

Small Mutations Identified through Deep DNA Sequencing for AML and MDS
Deep DNA sequencing analysis conducted by Rutgers Cancer Institute of New Jersey investigators examining genomic differences within tumors for prediction of disease relapse in certain hematologic malignancies has identified small mutations. These may help further guide treatment decision making for patients.
NEW TWIST ON CRISPR TECHNOLOGY
Researchers at the University of Delaware, using the revolutionary new genetic technology known as CRISPR/Cas9 have found a way to improve the efficiency and precision of the way enzymes work together to produce certain biochemical reactions in cells. Their new application essentially creates a dynamic assembly line that can lead to advances in pharmaceuticals, agriculture and biofuels.