Dual immunotherapy plus chemotherapy benefits specific subset of patients with lung cancer

Researchers from The University of Texas MD Anderson Cancer Center have demonstrated that patients with metastatic non-squamous non-small cell lung cancer (NSCLC) harboring specific mutations in the STK11 and/or KEAP1 tumor suppressor genes were more likely to benefit from adding the immunotherapy tremelimumab to a combination of durvalumab plus chemotherapy to overcome treatment resistance typically seen in this patient population.

ReadCube expands literature management with new AI Assistant and comprehensive search

Digital Science announces the AI-powered ReadCube Pro, offering researchers new tools to simplify and accelerate literature management and literature monitoring workflows.

Greenhouse gains: cucumbers get a genetic upgrade through innovative pollen tech

Researchers have achieved a groundbreaking advancement in plant biotechnology by using a magnetofected pollen gene delivery system to genetically transform cucumbers. This cutting-edge method uses DNA-coated magnetic nanoparticles to introduce foreign genes into pollen, producing genetically modified seeds without the need for traditional tissue culture or regeneration steps. This technique significantly streamlines and accelerates crop genetic modification, opening up new avenues to boost agricultural productivity and resilience.

Bulwark of blooms: the lily’s secret armor against plant pathogens

A cutting-edge study reveals the biochemical defense system of the wild lily, Lilium regale, which demonstrates remarkable resistance against Fusarium wilt—a major threat to the floriculture industry. The research uncovers the lily’s robust defense mechanisms, spotlighting the critical role of phenylpropanoid metabolism and the regulatory influence of specific transcription factors. These findings offer valuable insights for developing crops with enhanced disease resistance.

New brain-computer interface allows man with ALS to ‘speak’ again

A brain-computer interface developed by UC Davis Health accurately translates brain signals into speech. The device implanted in the brain of a man with ALS is the most accurate system of its kind.

Harrisburg University Research Roundup: July 2024

Harrisburg, PA – Welcome to your July 2024 Harrisburg University of Science and Technology (HU) Research Roundup! Our talented students and faculty members are busy presenting at conferences, publishing boundary-pushing research, and building fruitful partnerships with schools, agencies, and organizations.…

JMIR XR and Spatial Computing is inviting submissions for a new theme issue titled “First Look: Early Research, Viewpoints, and Experiences with Apple Vision Pro in Health Care Settings”

JMIR Publications invites submissions to a new theme issue titled “First Look: Early Research, Viewpoints, and Experiences with Apple Vision Pro in Health Care Settings” in its new open access journal JMIR XR and Spatial Computing.

Blueprint for blueberry: decoding the genetic pathways of plant regrowth

A pivotal study has shed light on the genetic factors that govern the ability of highbush blueberries to regenerate from shoots, a critical process for plant breeding and genetic engineering. By comparing the transcriptomes of two genotypes with contrasting regeneration rates, researchers identified key auxin-related genes and transcription factors crucial to this process.

Unraveling the DNA mystique of Saposhnikovia divaricata: new horizons in herbal medicine

In a pioneering study, scientists have decoded the genetic blueprint of Saposhnikovia divaricata, a traditional medicinal herb. The research provides a detailed genome sequence, shedding light on the plant’s evolutionary adaptations and the genetic foundations of its therapeutic benefits.

Yeast Fuel, Developed by Chula’s Faculty of Science Soon to Expand Its Production for the Aerospace Industry

Researchers from Chulalongkorn University have made use of forage grass to feed microorganisms and convert the resulting fat into jet fuel. They aim to expand petroleum-based oil replacement production to reduce impacts on human health and the environment.

Intensity Therapeutics, Inc. Announces First Patient Dosed in its Global Randomized, Phase 3 Study (INVINCIBLE-3) in Metastatic Soft Tissue Sarcoma

Intensity Therapeutics, Inc. , a late-stage clinical biotechnology company focused on the discovery and development of proprietary, novel immune-based intratumorally injected cancer therapies intended to kill tumors directly and increase immune system recognition of cancers, announces that the first U.S. patient has been dosed in the Company’s Phase 3 study to treat metastatic sarcoma (NCT06263231).

Biotech entrepreneur donates $50 million to UC Irvine School of Biological Sciences

The University of California, Irvine has received a $50 million donation from Orange County biotech entrepreneur Charlie Dunlop for the School of Biological Sciences. Dean Frank LaFerla announced the gift before thousands of graduating students, faculty and family supporters at today’s school commencement, where Dunlop was the featured speaker.

Unlocking the grape’s secret scent: key gene modulates terpene aroma

A study explores the ethylene-responsive gene VviERF003’s influence on glycosylated monoterpenoid synthesis in grapes, which are pivotal for the fruity and floral notes in wines. Understanding this genetic regulation provides insights into how wine aroma can be influenced, potentially allowing for the development of grapes with enhanced or specific aromatic profiles.

Brookhaven Lab Biophysicist F. William Studier Awarded Merkin Prize in Biomedical Technology

F. William Studier, a senior biophysicist emeritus at the U.S. Department of Energy’s ‘Brookhaven National Laboratory, has won the 2024 Richard N. Merkin Prize in Biomedical Technology for his development in the 1980s of an efficient, scalable method of producing RNA and proteins in the laboratory.

Cello-gum Innovation Revolutionizes the Food Industry: Turning Coconut Jelly Biowaste into Billions in Raw Material Value

“Cello-gum”, a groundbreaking innovation by Prof. Dr. Hathaikarn Manuspiya from the Petroleum and Petrochemical College at Chulalongkorn University, transforms coconut jelly biowaste into valuable food ingredients worth billions of baht.

Biotechnology CEO and Inventor of SiriusXM Satellite Radio Martine Rothblatt to Deliver Graduation Address to the University of Maryland School of Medicine’s 215th Graduating Class

University of Maryland School of Medicine (UMSOM) Dean Mark T. Gladwin, MD, announced today that Martine Rothblatt PhD, JD, MBA, Chairperson and CEO of United Therapeutics, and inventor of SiriusXM Satellite Radio, will deliver the keynote address for this year’s graduating medical student class. The UMSOM MD graduation ceremony will take place at the Hippodrome Theatre on Thursday, May 16, 2024.

Membrane Technology: Looking Deep into Smallest Pores

Membranes of vertically aligned carbon nanotubes (VaCNT) can be used to clean or desalinate water at high flow rate and low pressure. Recently, researchers of Karlsruhe Institute of Technology (KIT) and partners carried out steroid hormone adsorption experiments to study the interplay of forces in the small pores. They found that VaCNT of specific pore geometry and pore surface structure are suited for use as highly selective membranes. The researchers report in Nature Communications. (DOI: 10.1038/s41467-024-44883-2)

Rakuten Medical Presents AI-based Study in Two Posters on Immune Characteristics in Responders and Cellular Level Drug Quantification of Alluminox Treatment (Photoimmunotherapy) at SITC 2023

Rakuten Medical, Inc., a global biotechnology company developing and commercializing precision, cell-targeted therapies based on its proprietary Alluminox™ platform today announced the presentation of two posters of AI-based analyses at the 38th Annual Meeting of the Society for Immunotherapy of Cancer (SITC), held November 3-5, 2023, in San Diego, CA (SITC 2023).

Green Genetic Engineering: Making Mendel’s Dream Come True with Molecular Scissors

Molecular biologist Professor Holger Puchta from Karlsruhe Institute of Technology (KIT) is granted funding within a Reinhart Koselleck Project by the German Research Foundation (DFG) for work on specific restructuring of plant genomes. Puchta, a pioneer of green genetic engineering,…

Department of Energy Announces $80 Million for Research to Accelerate Innovations in Emerging Technologies

Today, the U.S. Department of Energy (DOE) announced $80 million, provided by the Office of Science, to support fundamental research to drive the innovation cycle in support of the Accelerate Innovations in Emerging Technologies (Accelerate) initiative.

UC San Diego Awarded $8M to Expand Stem Cell Therapy Clinical Trials

UC San Diego Alpha Stem Cell Clinic awarded $8M to expand clinical trials of novel stem cell therapies. The CIRM award will advance partnerships between academic and industry experts in San Diego to expedite clinical trials for patients with difficult-to-treat diseases.