Researchers discover a new way in which insulin interacts with its receptor

The biological actions of insulin are mediated by its receptor—the insulin receptor—which is localized on the cell surface. In a new study, researchers from Germany, Canada, and Finland show how insulin interacts with its receptor at a second binding site. The scientists hope that these new details concerning insulin–receptor interactions will ultimately expand the current models of insulin binding to its receptor and pave the way towards new approaches to structure-based drug design.

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Researchers engineer insulin-producing cells activated by light for diabetes

Researchers have transplanted engineered pancreatic beta cells into diabetic mice, then caused the cells to produce more than two to three times the typical level of insulin by exposing them to light. The light-switchable cells are designed to compensate for the lower insulin production or reduced insulin response found in diabetic individuals.

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Artificial Pancreas System Better Controls Blood Glucose Levels than Current Technology

Study based at the Icahn School of Medicine at Mount Sinai and other centers finds new system has safety, efficacy benefits for people with type 1 diabetes

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