Neurons stripped of their identity are hallmark of Alzheimer’s disease, study finds

Researchers at the University of California San Diego have identified new mechanisms in neurons that cause Alzheimer’s disease. In particular, they discovered that changes in the structure of chromatin, the tightly coiled form of DNA, trigger neurons to lose their specialized function and revert to an earlier cell state. This results in the loss of synaptic connections, an effect associated with memory loss and dementia.

Read more

Researchers Use Lab-grown Tissue Grafts for Personalized Joint Replacement

A multidisciplinary team from Columbia Engineering, Columbia’s College of Dental Medicine and Department of Medicine, Louisiana State University, LaCell LLC, and Obatala Sciences has now bioengineered living cartilage-bone temporomandibular joint grafts, precisely matched to the recipient, both biologically and anatomically. Their new study, published today in Science Translational Medicine, builds upon a long series of their previous work on bioengineering functional cartilage and bone for regenerative medicine and tissue models of disease.

Read more

Machine Learning Takes on Synthetic Biology: Algorithms Can Bioengineer Cells for You

Scientists at Lawrence Berkeley National Laboratory have developed a new tool that adapts machine learning algorithms to the needs of synthetic biology to guide development systematically. The innovation means scientists will not have to spend years developing a meticulous understanding of each part of a cell and what it does in order to manipulate it.

Read more

Scientists Aim Gene-Targeting Breakthrough Against COVID-19

Scientists at Berkeley Lab and Stanford have joined forces to aim a gene-targeting, antiviral agent called PAC-MAN against COVID-19.

Read more

Engineers develop low-cost, high-accuracy GPS-like system for flexible medical robots

Roboticists at the University of California San Diego have developed an affordable, easy to use system to track the location of flexible surgical robots inside the human body. The system performs as well as current state of the art methods, but is much less expensive.

Read more