T cells | sciencenewsnet.in

A closer look at T cells reveals big differences in mild vs. severe COVID-19 cases

January 21, 2021 sarah Jonas COVID-19, T cells

A big question on people’s minds these days: how long does immunity to SARS-CoV-2 last following infection?

Now a research team from La Jolla Institute for Immunology (LJI), The University of Liverpool and the University of Southampton has uncovered an interesting clue. Their new study suggests that people with severe COVID-19 cases may be left with more of the protective “memory” T cells needed to fight reinfection.

Research Results

Immunology study finds protein critical to T cell metabolism and anti-tumor immune response

January 4, 2021 sarah Jonas Immunology, Melanoma, metabolism and cancer, T cells

Researchers at The University of Texas MD Anderson Cancer Center have discovered that a protein called NF-kappa B-inducing kinase (NIK) is essential for the shift in metabolic activity that occurs with T cell activation, making it a critical factor in regulating the anti-tumor immune response.

Research Results

Weizmann Institute of Science and Colleagues Show How Cancer Cells Hurt Themselves to Hurt Immune Cells More

December 16, 2020 sarah Jonas Amino Acids, IDO1, Melanoma, mRNA, Skin Cancer, T cells, Tryptophan

Melanoma is skilled at evading therapies, with its cells going so far as to starve in order to stop the immune cells that would eradicate them. A team from the Weizmann Institute, including Prof. Yardena Samuels; the Netherlands Cancer Institute; and the University of Oslo have revealed one of melanoma’s tricks – never before seen in human cells – and a therapeutic target.

Research Results

New study points to a better way to ward off asthma triggers

November 11, 2020 sarah Jonas Asthma, lung, T cells

While quick-acting inhalers and medications can reduce inflammation during an asthma attack, people with asthma have few tools to prevent the next attack from coming. Now researchers at La Jolla Institute for Immunology (LJI) have discovered that blocking two immune molecules at the same time is key to preventing asthma attacks in a mouse model.

Research Results

New Population of Immune Cells Could Play a Role in Multiple Sclerosis

October 23, 2020 sarah Jonas Multiple Sclerosis (MS), T cells

Researchers uncover defining features of a subset of T-cells that may drive autoimmunity in MS, and could prove to be a new target for therapy.

Research Results

T cells take the lead in controlling SARS-CoV-2 and reducing COVID-19 disease severity

September 16, 2020 sarah Jonas COVID-19, SARS-CoV-2, T cells

A multi-layered, virus-specific immune response is important for controlling SARS-CoV-2 during the acute phase of the infection and reducing COVID-19 disease severity, with the bulk of the evidence pointing to a much bigger role for T cells than antibodies.

Research Results

T cells can shift from helping to harming in atherosclerosis

July 24, 2020 sarah Jonas Atherosclerosis, Cholesterol, Heart Disease, LDL, Regulatory T Cells, T cells

At La Jolla Institute for Immunology (LJI) researchers are dedicated to finding a way to stop plaques from forming in the first place. In a new study, LJI scientists show that certain T lymphocytes, a type of white blood cell, that start out trying to fight the disease can end up increasing inflammation and making atherosclerosis cases even worse.

Research Results

Boosting Immune Memory Could Reduce Cancer Recurrence

July 14, 2020 sarah Jonas checkpoint, Immunotherapy, T cells

New study on how immune memory can be targeted and improve immunotherapy and prevent cancer recurrence.

Research Results

Even in the worst COVID-19 cases, the body launches immune cells to fight back

June 29, 2020 sarah Jonas COVID-19, T cells

SHAREInternational collaboration provides important piece of COVID-19 puzzleLA JOLLA—A new study from researchers at La Jolla Institute for Immunology (LJI) and Erasmus University Medical Center (Erasmus MC) shows that even the sickest COVID-19 patients produce T cells that help fight the virus. The study offers further evidence that a COVID-19 vaccine will need to elicit T cells to work alongside antibodies.

Research Results

Paying the Price of Protection

May 19, 2020 sarah Jonas Alon, Autoimmune Disease, Computer Modeling, Hormones, T cells, Thyroid Disease

A new Weizmann Institute model of autoimmune disease may solve some major outstanding riddles, including what causes T cells to attack and why only certain organs get the diseases

Research Results

Mimicking Cancer’s Evasive Tactics, Microparticles Show Promise Against Transplant Rejection

March 13, 2020 sarah Jonas Cancer, Engineering, Immune System, T cells, Transplant

Inspired by a tactic cancer cells use to evade the immune system, University of Pittsburgh researchers have engineered tiny particles that can trick the body into accepting transplanted tissue as its own, while leaving the immune system intact.

Research Results

U-M Team Sheds New Light on the Role of Regulatory T Cells in Pancreatic Cancer

January 8, 2020 sarah Jonas 0 Comments Cancer, Pancreatic Cancer, T cells

A multidisciplinary Michigan Medicine team is shedding new light on the role of regulatory T cells in pancreatic cancer — and, in mouse models, have uncovered a new potential target to improve immunotherapy approaches to the deadly disease.

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