Scientists at Sanford Burnham Prebys have gained a deeper insight into the intricacies of autophagy, the process in which cells degrade and recycle cellular components.
A study published in the June 10, 2021 issue of Cell describes a remarkable new mechanism by which the body’s own immune system can eliminate cancer cells without damaging host cells. The findings have the potential to develop first-in-class medicines that are designed to be selective for cancer cells and non-toxic to normal cells and tissues.
The method reveals that the lattice, which forms the major structural component of the human immunodeficiency virus (HIV), is dynamic. The discovery of a diffusing lattice made from Gag and GagPol proteins, long considered to be completely static, opens up potential new therapies. The method can be applied to biomedical structure.
By combining the fine-grained detail available from animal studies with the statistical power of genetic studies involving hundreds of thousands of human genomes, researchers have discovered a new gene involved in regulating the body’s cholesterol.
Life as we know it requires phosphorus, which is scarce. How did the early Earth supply this key ingredient? A University of Washington study, published Dec. 30 in the Proceedings of the National Academy of Sciences, finds answers in certain types of carbonate-rich lakes.
Scientists consider the form that may be “just right” for scripting gene expression The Goldilocks of fairy-tale fame knew something about porridge. It needed to be just right—neither too hot nor too cold. Same with furniture—neither too hard nor too…