Could neutrophils be the secret to cancer’s Achilles’ heel?

A study published in the June 10, 2021 issue of Cell describes a remarkable new mechanism by which the body’s own immune system can eliminate cancer cells without damaging host cells. The findings have the potential to develop first-in-class medicines that are designed to be selective for cancer cells and non-toxic to normal cells and tissues.

Pioneering method reveals dynamic structure in HIV

The method reveals that the lattice, which forms the major structural component of the human immunodeficiency virus (HIV), is dynamic. The discovery of a diffusing lattice made from Gag and GagPol proteins, long considered to be completely static, opens up potential new therapies. The method can be applied to biomedical structure.

Life could have emerged from lakes with high phosphorus

Life as we know it requires phosphorus, which is scarce. How did the early Earth supply this key ingredient? A University of Washington study, published Dec. 30 in the Proceedings of the National Academy of Sciences, finds answers in certain types of carbonate-rich lakes.