Genethon announces first patient dosed in clinical trial of gene therapy for DMD
A first participant was dosed at I-Motion, the pediatric clinical trial platform for neuromuscular diseases located at Trousseau hospital in
Read moreGenetics
“Molecular Tomographer” algorithm maps gene expression in space
As we accumulate more and more gene-sequencing information, cell-type databases are growing in both size and complexity. There is a
Read moreSupplement treats schizophrenia in mice, restores healthy “dance” and structure of neurons
A simple dietary supplement reduces behavioral symptoms in mice with a genetic mutation that causes schizophrenia.
Read moreAttacking Aortic Aneurysms Before They Grow
New basic science research shows what happens to the development of abdominal aortic aneurysms when you inhibit JMJD3 through both genetics and pharmacology.
Read morePOT1 gene mutation predisposes to glioma and affects survival in a sex-specific manner
Researchers at Baylor College of Medicine and collaborators at other institutions have discovered that POT1, a gene known to be
Read moreClemson researchers find snake venom complexity is driven by prey diet
Diversity in diet plays a role in the complexity of venom in pit vipers such as rattlesnakes, copperheads and cottonmouths.
Read moreCNIO researchers explain the toxicity of USP7 inhibitors, under development for cancer treatment
Understanding the components that control cell division is fundamental to understanding how life works and how alterations in this delicate
Read moreCityU biologists discover super-enhancers that switch on breast cancer genes
Triple-negative breast cancer (TNBC) is an aggressive type of breast cancer with a high fatality rate. Currently, chemotherapy is the
Read moreResearchers demonstrate very high specificity of prime editors in plants
Prime editing (PE), a “search-and-replace” CRISPR-based genome editing technique, has great potential for gene therapy and agriculture. It can introduce
Read moreUnlocking new avenues for curing cancer: Cell receptor neuropilin-1 could hold the key
A growing body of research shows that inhibiting neuropilin-1 activity can slow tumor progression in several types of cancers
Read moreResearchers generate human-monkey chimeric embryos
Investigators in China and the United States have injected human stem cells into primate embryos and were able to grow
Read moreJapanese-European research team discovers novel genetic mitochondrial disorder
Team of Japanese and European scientists identify a novel genetic mitochondrial disorder by analyzing DNA samples from three distinct families
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Lab study solves textbook problem: How cells know their size
Scientists have searched for years to understand how cells measure their size. Cell size is critical. It’s what regulates cell division in a growing organism.
Read moreACMG Foundation announces 2021 recipients of Carolyn Mills Lovell Genetic Counselor Award
Adrienne Bailey, MS, CGC and Renee S. Jones, MS, LCGC are the recipients of the 2021 ACMG Foundation Carolyn Mills Lovell Genetic Counselor Award
Read moreACMG Foundation/David L. Rimoin Inspiring Excellence Award honors Catherine A. Ziats, MD
Catherine A. Ziats, MD Receives 2021 ACMG Foundation/ David L. Rimoin Inspiring Excellence Award
Read moreAdam Guenzel, PhD is the recipient of the 2021 Richard King Trainee Award
Adam Guenzel, PhD receives the 2021 Richard King Award for Best Publication by a Trainee in Genetics in Medicine
Read moreThe ACMG Foundation presents 2021 Pfizer/ACMG Foundation Next Generation Fellowship Awards
The ACMG Foundation for Genetic and Genomic Medicine presents 2021 Pfizer/ACMG Foundation Next Generation Fellowship Awards to Christina Tise, MD, PhD and Daniel Pomerantz, MD
Read moreLab study solves textbook problem: How cells know their size
The answer to a basic science question could unlock the key to complex medical challenges
Read moreNew genotyping services launched across CGIAR and partners
Low Density SNP Genotyping Services (LDSG) provide crop breeders streamlined and centralized service
Read moreBacteria that cause periodontitis are transmitted from parents to children
A study led by researchers at the University of Campinas reinforces the need for prevention and follow-up treatment starting in early childhood to avoid development of this inflammatory disease of the gums.
Read moreThe Chillest Ape: How Humans Evolved A Super-High Cooling Capacity
Humans have a uniquely high density of sweat glands embedded in their skin—10 times the density of chimpanzees and macaques. Now, researchers at Penn Medicine have discovered how this distinctive, hyper-cooling trait evolved in the human genome.
Read moreDNA structure itself is involved in genome regulation
DNA supercoiling is an important contributor to the control of gene expression, and not just collateral damage that cells have to solve
Read moreSimple genetic modification aims to stop mosquitoes spreading malaria
Genetically modifying mosquitoes to express antimalarial genes and pass them on to their offspring is being tested as a new strategy to eliminate malaria
Read moreCNIO scientists discovers a combination therapy for aggressive brain tumors
Glioblastomas are the most common and most aggressive brain tumours. Their survival rate has barely increased over the last 50
Read moreFamily ties: Early cardiac events pose major and different risks in close relatives
Family history of early cardiac events in first degree relatives such as a parent or sibling is a major risk
Read moreFor tomato genes, one plus one doesn’t always make two
Both people and tomatoes come in different shapes and sizes. That is because every individual has a unique set of
Read moreCancer DNA blood tests validated by international research team
An international team today reports the findings of an independent assessment of five commercially-available assays for tumour DNA sequencing –
Read moreHow a new malting barley variety for California came to be
Twenty-year process involved evaluating malting barley germplasm strains, breeding efforts
Read moreLiving fossils: Microbe discovered in evolutionary stasis for millions of years
It’s like something out of science fiction. Research led by Bigelow Laboratory for Ocean Sciences has revealed that a group
Read moreMutations in overlooked DNA could have profound impact on survival for bowel cancer patients
Mutations in the DNA of the cell’s energy ‘factories’ increases the chances of survival for people with bowel cancer, according
Read moreHow to tame a restless genome
Short pieces of DNA–jumping genes–can bounce from one place to another in our genomes. When too many DNA fragments move
Read moreThe best in AI appointed at Norwich Research Park
Scientists across Norwich Research Park institutes are part of a major integrated UK research-industry programme led by The Alan Turing
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Manual workers face twice the risk of developing ALS
ALS is a progressive neurological disease that attacks the nerves that interact with the body’s muscles. The disease typically leads to complete paralysis of the body, robbing patients of their ability to walk, speak, eat and breathe.
Read moreSingapore launches next phase of National Precision Medicine Programme
SINGAPORE, 7 April 2021 – Precision medicine is part of Singapore’s Research, Innovation and Enterprise (RIE) 2025 strategic goal to
Read moreCarnegie Mellon/Yale PNA-based technique an essential part of the gene editing toolkit
In an article published in the April 8 issue of Nature , the National Institutes of Health’s Somatic Cell Gene
Read moreReversing a genetic cause of poor stress responses in mice
Everyone faces stress occasionally, whether in school, at work, or during a global pandemic. However, some cannot cope as well
Read moreUrolithin A shows effective against muscular dystrophy
Progression of Duchenne Muscle Dystrophy (DMD) can be delayed in mice by supplementing their diets with Urolithin A, according to
Read moreNew Lyme disease test distinguishes between early and late-stage disease
New test targets genetic sequences in Lyme-causing bacteria and is highly sensitive, detecting just one bacterial cell in a blood sample
Read moreThe incredible bacterial ‘homing missiles’ that scientists want to harness
A Berkeley Lab-led team is digging into the bizarre bacteria-produced nanomachines that could fast-track microbiome science
Read moreAn international study reveals how the ‘guardian’ of the genome works
The study is published in ‘Nature Structural & Molecular Biology’
Read moreGained in translation: Subgenome fractionation determines hybrid vigor in maize
Researchers trace the root of increased hybrid vigor in maize to differential translational fractionation of its subgenomes
Read moreBeing top baboon costs males their longevity
Struggle for dominance leaves a mark on genes and speeds up aging
Read moreCompeting for high status speeds up aging in male baboons
Study suggests that high social status contributes to accelerated aging in baboons, despite its other advantages
Read moreNew perspective to understand and treat a rare calcification disease
Researchers developed a new animal model to study a rare genetic disease that can lead to blindness at the age of 40-50.
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Overfishing of Atlantic Cod Likely Did Not Cause Genetic Changes
Overfishing likely did not cause the Atlantic cod, an iconic species, to evolve genetically and mature earlier, according to a study led by Rutgers University and the University of Oslo – the first of its kind – with major implications for ocean conservation.
Read moreResearchers develop a technique to produce transplantable livers in the laboratory
An extracellular matrix obtained by controlled decellularization is used to reconstruct the liver with human-like characteristics
Read moreUnusual mechanism in rare mutation associated with Alzheimer’s uncovered by UChicago researchers
A novel mechanism has been identified that might explain why a rare mutation is associated with familial Alzheimer’s disease in a new study by investigators at the University of Chicago.
Read moreHidden diversity of coral more important for conservation than previously thought
Researchers say that our framework for classifying coral species needs to be expanded to capture ecological diversity and protect reef environments
Read moreNew research on Alzheimer’s Disease shows ‘lifestyle origin at least in some degree’
For years, research to pin down the underlying cause of Alzheimer’s Disease has been focused on plaque found to be building up in the brain in AD patients.
Read moreGenome sequencing shows coronavirus variation drives pandemic surges
Fusing classical epidemiology and genomics is a tool for future pandemics
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