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UrduLearn how ancestry changes genetic risk variants’ impact on type 2 diabetes in childhood cancer survivors & alkylating agent exposure magnifies diabetes risk.
Tag: Genetic Risk
Higher Genetic Risk of Obesity Means Working Out Harder for Same Results
Persons with a higher genetic risk of obesity need to work out harder than those of moderate or low genetic risk to avoid becoming obese, according to a Vanderbilt University Medical Center (VUMC) paper published in JAMA Network Open.
Genetic risk prediction for 10 chronic diseases moves closer to the clinic
As part of a nationwide collaboration, Broad Clinical Labs researchers have optimized 10 polygenic scores for use in clinical research as part of a study on how to implement genetic risk prediction for patients.
Neighborhood Access to Alcohol Might be Linked to A Raised Risk of Suicide Attempts
Living in a neighborhood with bars or government-run alcohol outlets may increase suicidal behavior among young adults, especially men and those with elevated genetic liability for attempting suicide, a new study suggests. The paper, in Alcohol: Clinical & Experimental Research, is the latest attempt to clarify the link between alcohol accessibility and suicidal behavior. This complex relationship is proving difficult to unravel. Both acute drinking and alcohol use disorder are associated with increased suicide risk, potentially because of behavioral inhibition, depressed mood, or aggression. The link between heavy drinking and suicidal behavior likely reflects, in part, genetic and environmental influences, including the proximity of alcohol outlets. Research has been inconclusive, however. For the new study, drawing on the experiences of hundreds of thousands of individuals in Sweden, investigators explored the association between neighborhood alcohol outlets and suicide attempts and
High Caffeine Consumption may be Associated with Increased Risk of Blinding Eye Disease
Frequent caffeine intake could more than triple risk of glaucoma for those genetically predisposed to higher eye pressure
Study Finds Certain Genetic Test Not Useful in Predicting Heart Disease Risk
A Polygenic Risk Score — a genetic assessment that doctors have hoped could predict coronary heart disease (CHD) in patients — has been found not to be a useful predictive biomarker for disease risk, according to a Vanderbilt study published in the Journal of the American Medical Association.