Neurodegenerative Disease | sciencenewsnet.in

The Novel Role of Microglia as Modulators of Neurons in the Brain Is Discovered by Mount Sinai Researchers

September 30, 2020 sarah Jonas adenosine triphosphate, Alzheimer's Disease, ATP, Epigenetics, Icahn School of Medicine at Mount Sinai, Inflammatory Diseases, Microglia, Mount Sinai Health System, Neurodegenerative Disease, Neurodegenerative Diseases, Neuromodulation, Neuronal Activity

Findings offer potential target for treating behavioral abnormalities associated with neurodegenerative conditions like Alzheimer’s Disease

Research Results

World’s First ‘Pathoconnectome’ Could Point Toward New Treatments for Neurodegenerative Diseases

September 29, 2020 sarah Jonas Alzheimer's Disease, Epilepsy, Neurodegenerative Disease, Retina

Scientists from the John A. Moran Eye Center at the University of Utah have achieved another first in the field of connectomics, which studies the synaptic connections between neurons. The National Institutes of Health (NIH)-funded lab has produced the first pathoconnectome, showing how eye disease alters retinal circuitry.

Research Results

Concussion discovery reveals dire, unknown effects of even mild brain injury

September 10, 2020 sarah Jonas Aging, Alzheimer's Disease, Athletes, BIG Center, Brain, Brain Injury, Center for Brain Immunology and Glia, Concussions, Dementia, Football, John Lukens, Military, National Football League, Neurodegenerative Disease, Neuroimmunology, Neurological Disease, Neuroscience, NFL, Soccer, Sports, TBI, Traumatic Brain Injury, University Of Virginia, University of Virginia School of Medicine, UVA, UVA School of Medicine

Even mild concussions cause severe and long-lasting impairments in the brain’s ability to clean itself, and this may seed it for Alzheimer’s, dementia and other neurodegenerative problems.

Research Results

Researchers discover how cells clear misfolded proteins from tissues

February 18, 2020 sarah Jonas Alzheimer's Disease, Neurodegeneration, Neurodegenerative Disease

Researchers in Japan have identified a new quality control system that allows cells to remove damaged and potentially toxic proteins from their surroundings. The study, which will be published February 18 in the Journal of Cell Biology, finds that the Clusterin protein and heparan sulfate proteoglycans combine to bring misfolded proteins into cells for degradation. The findings may lead to new therapeutic targets for neurodegenerative disorders, including Alzheimer’s disease.