Novel pathology could improve diagnosis and treatment of Huntington’s and other diseases

Bristol scientists have discovered a novel pathology that occurs in several human neurodegenerative diseases, including Huntington’s disease.

The article, published in Brain Pathology, describes how SAFB1 expression occurs in both spinocerebellar ataxias and Huntington’s disease and may be a common marker of these conditions, which have a similar genetic background.

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Parkinson’s Disease May Start Before Birth

People who develop Parkinson’s disease before age 50 may have been born with disordered brain cells that went undetected for decades, according to EMBARGOED Cedars-Sinai research that will publish Jan. 27 in the journal Nature Medicine. The research points to a drug that potentially might help correct these disease processes.

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NINDS Awards Coriell Institute for Medical Research $7.7 Million Contract

The five-year award will support the NINDS Human Genetics Resource Center, a collection of biological samples and corresponding demographic, clinical, and genetic data made available to qualified researchers around the world. This repository includes samples from subjects with various diseases – such as cerebrovascular disease, dystonia, epilepsy, motor neuron disease, parkinsonism, and Tourette Syndrome.

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