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UrduNeuroTherapia, an early-stage clinical pharmaceutical company, announced today that it has received a grant from the Alzheimer’s Association Part the Cloud program for the development of its first-in-class drug, NTRX-07, for the treatment of Alzheimer’s disease (AD).
Tag: Neuroinflammation
Research offers hope for preventing post-COVID ‘brain fog’ by targeting brain’s blood vessels
In a study of mice, researchers identified a mechanism that causes post-infection neurological problems
Fatty food before surgery may impair memory in old, young adults
Eating fatty food in the days leading up to surgery may prompt a heightened inflammatory response in the brain that interferes for weeks with memory-related cognitive function in older adults – and, new research in animals suggests, even in young adults.
Research Team Discovers Potential Alzheimer’s Drug
A potential new drug to prevent Alzheimer’s disease in people with the so-called Alzheimer’s gene has been discovered by a University of Arkansas for Medical Sciences (UAMS) research team led by Sue Griffin, Ph.D.
Brain-Belly Connection: Gut Health May Influence Likelihood of Developing Alzheimer’s
UNLV study pinpoints 10 bacterial groups associated with Alzheimer’s disease, provides new insights into the relationship between gut makeup and dementia.
Cocaine Use Disorder Alters Gene Networks of Neuroinflammation and Neurotransmission in Humans
Analysis reveals similar changes in the brain’s functioning in both humans and mouse models
Exposure to World Trade Center Dust Exacerbates Cognitive Impairment in an Animal Model of Alzheimer’s
Also evokes central and peripheral pro-inflammatory responses
FAU, Israel Scientists ‘Team Up’ to Tackle Alzheimer’s-related Mood Disorders
Researchers from Florida Atlantic University, in collaboration with Tel Aviv University, have received a two-year, $379,177 grant from the National Institute on Aging, National Institutes for Health, on a collaborative project to study mood-disorders changes in Alzheimer’s disease.
Anti-inflammatory compound shows potential in treating patients with severe COVID-19
An anti-inflammatory compound may have the potential to treat systemic inflammation and brain injury in patients with severe COVID-19 and significantly reduce their chances of death, according to a new study from UTHealth Houston and other institutions.
Spontaneous Mammary Neoplasia, Cannabidiol Exposure, Aryl Hydrocarbon Receptors, and More Featured in July 2021 Toxicological Sciences
Toxicological Sciences delivers the latest toxicology research in the July 2021 issue. The issue features investigations in delivers the latest toxicology research in areas such as exposure to delta-9-tetrahydrocannabinol and cannabidiol, effects of ENDS vapors on amino acid metabolism, and more.
Research Highlights from 2021 ACSM Virtual Annual Meeting: Exercise in Regenerative Medicine
The 2021 Virtual ACSM Basic Science World Congress focuses on regenerative medicine. Chaired by Marcas M. Bamman, Ph.D., FACSM, from the University of Alabama at Birmingham, this world congress brings together researchers to discuss cutting-edge science in this rapidly developing field.
Regulatory T cells could lead to new immunotherapies aimed at treating multiple sclerosis
In a new University of California, Irvine-led study, researchers have discovered how regulatory T cells (Treg) are instrumental in limiting the damage caused to the spinal cord in diseases like multiple sclerosis (MS).
Targeting the LANDO pathway holds a potential clue to treating Alzheimer’s disease
Reducing neuroinflammation by disrupting a protein involved in recycling cellular components may provide a potential therapeutic approach for treating neurodegeneration and memory loss.
Immune from Chronic Stress? Limit Inflammatory Signaling to Specific Brain Circuits
Chronic stress is associated with the pathogenesis of psychological disorders such as depression. A study is the first to identify the role of a neuronal receptor that straddles the intersection between social stress, inflammation, and anxiety in rodent models of stress. Findings suggest the possibility of developing better medications to treat the consequences of chronic stress by limiting inflammatory signaling not just generally, which may not be beneficial in the long run, but to specific brain circuits.
FAU Scientists Receive $1.7 Million NIH Grant for Novel Neuroinflammation Study
Researchers have received a $1.7 million NIH grant for a novel project that is the first to investigate how the inflammatory cytokine interleukin-1 (IL-1) influences neurotransmission through a direct action on neurons and how this action triggers behavioral changes. They will establish nIL-1R1 as a crucial link that could convert neuroinflammation to neural dysfunction, providing a new pathogenic mechanism for anxiety, depression, and cognitive dysfunction. Results from this work could suggest new targets for the treatment of psychopathology.
Gut Microbes May Improve Stroke Recovery
New research by the University of Kentucky’s College of Medicine reveals that supplementing the body’s short chain fatty acids could improve stroke recovery.