New Articles on Using Machine Learning to Predict Mammalian Acute Oral Toxicity and the Effects of Vinyl Chloride on Metabolism

The May 2023 issue of Toxicological Sciences includes articles on profiling mechanisms that drive acute oral toxicity in mammals and its prediction via machine learning and how vinyl chloride enhances high-fat diet-induced proteome alterations in the mouse pancreas related to metabolic dysfunction.

EPA grant to Wayne State to evaluate chemical mixture health risks

There are hidden metabolic health impacts in things that most people encounter every day. From surface cleaners to silicone wristbands, from fracking fluids to wastewater — even household dust — these diverse environmental mixtures have a potential to disrupt human health. A grant from the EPA to Wayne State University will evaluate the risks of chemical mixtures on health.

Exploring How Diethylene Glycol Poisons the Kidney and the Combined Effects of St. John’s Wort and Acetaminophen on the Liver

A ToxSpotlight article in the November 2022 issue of ToxSci assesses the mechanism for cellular accumulation of diglycolic acid while another explores the effect of long-term St. John’s wort administration on acetaminophen-induced acute hepatotoxicity and the involved mechanisms.

A Need to Consistently Characterize Aerosol Research Associated with E-cigarettes Is Featured in New Issue of ToxSci

Other featured research in October 2022 issue involves an exploration of a pharmacokinetic model for quantifying the mother-to-child transfer of environmental chemicals and how febuxostat may increase the risk for cardiovascular events by dysregulating calcium dynamics.

The Effects of Copper, Patient-Relevant Tissue Models, and Artificial Intelligence Featured in Sept. 2022 Issue of ToxSci

A new ToxPoint articles argues that “Copper Is the New Showstopper,” while a commentary calls for patient-relevant tissue models in the September 2022 issue of Toxicological Sciences (ToxSci), the official journal of the Society of Toxicology (SOT). Other featured articles…

WVU toxicologist calls passage of burn pit bill ‘critical step in improving veteran health’

A West Virginia University researcher with expertise in air pollution and inhalation exposures is available to discuss burn pits following this week’s U.S. Senate passage of a bill expanding health care benefits for veterans who developed illnesses after being exposed…

Pituitary Reproductive Regulatory Factors, Mercury Levels, and More Featured in November 2021 Toxicological Sciences

In the November 2021 issue, Toxicological Science features leading toxicology research in areas such as biomarkers, carcinogenesis, and environmental toxicology.

Rutgers Toxicologist Available to Discuss Dangers of Taking Iodine to Treat COVID-19

Professor Lewis Nelson, M.D., is available to discuss the dangers of gargling, snorting, or ingesting Betadine, an iodine-based antiseptic to treat COVID-19. “Although many topical disinfectants such as povidone-iodine, which, is also known as Betadine, generally destroy viruses on direct…

Drug-Induced Liver Injury, Prenatal Developmental Toxicity, and More Featured in September 2021 Toxicological Sciences

The September 2021 issue of Toxicological Sciences contains leading toxicological research, exploring nanotoxicology, neurotoxicology, immunotoxicology, and more.

Spontaneous Mammary Neoplasia, Cannabidiol Exposure, Aryl Hydrocarbon Receptors, and More Featured in July 2021 Toxicological Sciences

Toxicological Sciences delivers the latest toxicology research in the July 2021 issue. The issue features investigations in delivers the latest toxicology research in areas such as exposure to delta-9-tetrahydrocannabinol and cannabidiol, effects of ENDS vapors on amino acid metabolism, and more.

Prevention, detection and various approaches on coronaviruses

In this difficult period of the SARS-CoV-2 (and its variants) infection responsible for Covid-19 diseases, the importance of scientific works and reviews dealing with these viruses has never been more essential. This book Coronavirus brings together essential data regarding prevention…

Scientists find liver drug candidates among pesticides

Skoltech biologists and their colleagues from Koltzov Institute of Developmental Biology, Russia, and the Chemistry Department of Taras Shevchenko University in Ukraine have discovered fairly unlikely drug candidates for treating liver fibrosis and other pathologies — among pest control chemicals.…

Is global plastic pollution nearing an irreversible tipping point?

Common press release: Stockholm University, Norwegian Geotechnical Institute, Alfred Wegener Institute Helmholtz Centre for Polar and Marine Research, Helmholtz Centre for Environmental Research

How lead (maybe) caused the downfall of ancient Rome (video)

WASHINGTON, June 28, 2021 — Ancient Rome’s emperors did some pretty bizarre stuff — bursting into uncontrollable fits of laughter, appointing a horse as a priest, dressing in animal skins and attacking people … the list goes on. Why were…

Unlabeled PFAS chemicals detected in makeup

Makeup wearers may be absorbing and ingesting potentially toxic per- and polyfluoroalkyl substances (PFAS), according to a new study published today in Environmental Science & Technology Letters . The researchers found high fluorine levels–indicating the probable presence of PFAS–in most…

Higher alcohol content beer popularity growing, as overall beer consumption down

PITTSBURGH, June 10, 2021 – Americans are consuming more craft beer with higher alcohol content but are drinking less beer by volume, according to a new analysis led by epidemiologists at the University of Pittsburgh Graduate School of Public Health.…

UN: More harmful algal bloom impacts emerge amid rising seafood demand, coastal development

UNESCO IOC delivers 1st global assessment report after 7 years’ work by 109 experts in 35 countries, creating a baseline to detect and gauge the changing distribution, frequency, and intensity of harmful — often poisonous — algal blooms

Metal Contamination, Gene Signatures, Bisphenol F, and More Featured in June 2021 Toxicological Sciences

Toxicological Sciences delivers the latest research in toxicology, in areas such as clinical and translational toxicology; emerging technologies, methods, and models; and environmental toxicology.

Deciphering Gene-Environment Interactions in Parkinson’s Disease

The interaction between an individual’s genetics and their local environment plays a critical role in an individual’s likelihood of getting Parkinson’s disease. In this perspective, researchers highlight how a common fly could be used to better understand the complex interactions…