Spontaneous Mammary Neoplasia, Cannabidiol Exposure, Aryl Hydrocarbon Receptors, and More Featured in July 2021 Toxicological Sciences

Toxicological Sciences delivers the latest toxicology research in the July 2021 issue. The issue features investigations in delivers the latest toxicology research in areas such as exposure to delta-9-tetrahydrocannabinol and cannabidiol, effects of ENDS vapors on amino acid metabolism, and more.

Prevention, detection and various approaches on coronaviruses

In this difficult period of the SARS-CoV-2 (and its variants) infection responsible for Covid-19 diseases, the importance of scientific works and reviews dealing with these viruses has never been more essential. This book Coronavirus brings together essential data regarding prevention…

Scientists find liver drug candidates among pesticides

Skoltech biologists and their colleagues from Koltzov Institute of Developmental Biology, Russia, and the Chemistry Department of Taras Shevchenko University in Ukraine have discovered fairly unlikely drug candidates for treating liver fibrosis and other pathologies — among pest control chemicals.…

Is global plastic pollution nearing an irreversible tipping point?

Common press release: Stockholm University, Norwegian Geotechnical Institute, Alfred Wegener Institute Helmholtz Centre for Polar and Marine Research, Helmholtz Centre for Environmental Research

How lead (maybe) caused the downfall of ancient Rome (video)

WASHINGTON, June 28, 2021 — Ancient Rome’s emperors did some pretty bizarre stuff — bursting into uncontrollable fits of laughter, appointing a horse as a priest, dressing in animal skins and attacking people … the list goes on. Why were…

Unlabeled PFAS chemicals detected in makeup

Makeup wearers may be absorbing and ingesting potentially toxic per- and polyfluoroalkyl substances (PFAS), according to a new study published today in Environmental Science & Technology Letters . The researchers found high fluorine levels–indicating the probable presence of PFAS–in most…

Higher alcohol content beer popularity growing, as overall beer consumption down

PITTSBURGH, June 10, 2021 – Americans are consuming more craft beer with higher alcohol content but are drinking less beer by volume, according to a new analysis led by epidemiologists at the University of Pittsburgh Graduate School of Public Health.…

UN: More harmful algal bloom impacts emerge amid rising seafood demand, coastal development

UNESCO IOC delivers 1st global assessment report after 7 years’ work by 109 experts in 35 countries, creating a baseline to detect and gauge the changing distribution, frequency, and intensity of harmful — often poisonous — algal blooms

Metal Contamination, Gene Signatures, Bisphenol F, and More Featured in June 2021 Toxicological Sciences

Toxicological Sciences delivers the latest research in toxicology, in areas such as clinical and translational toxicology; emerging technologies, methods, and models; and environmental toxicology.

Deciphering Gene-Environment Interactions in Parkinson’s Disease

The interaction between an individual’s genetics and their local environment plays a critical role in an individual’s likelihood of getting Parkinson’s disease. In this perspective, researchers highlight how a common fly could be used to better understand the complex interactions…

UNH research: Journey of PFAS in wastewater facilities highlights regulation challenges

DURHAM, N.H.–Researchers at the University of New Hampshire have conducted two of the first studies in New England to collectively show that toxic man-made chemicals called PFAS (per-and polyfluoroalkyl substances), found in everything from rugs to product packaging, end up…

As water sources become scarce, understanding emerging subsurface contaminants is key

USC researchers modeled complex subsurface water flow to help assess the risk of contaminants appearing in high, unsafe concentrations in variable water sources.

Colorado School of Public Health receives grant to address kidney disease among women in Guatemala

The three-year K01 grant from the National Institute of Environmental Health Sciences provides support to examine the environmental determinants of kidney injury in female sugarcane workers and female community members in Guatemala

Which medications are most toxic to the liver?

A new study published in the British Journal of Clinical Pharmacology ¬provides insights on how common hospitalized patients develop liver injury from taking different medications. When investigators analyzed the records of 156,570 hospitalized patients, they found 499 cases of drug-induced…

Epitranscriptomics, Xenobiotic Nuclear Receptors, Arsenic Exposure, and More Featured in May 2021 Toxicological Sciences

Research on biomarkers, carcinogenesis, regulatory science, and more is available in the latest issue of Toxicological Sciences.

Applying UV light to common disinfectants makes them safer to use

Over 400 common disinfectants currently in use could be made safer for people and the environment and could better fight the COVID-19 virus with the simple application of UVC light, a new study from the University of Waterloo shows. Benzalkonium…

CNIO researchers explain the toxicity of USP7 inhibitors, under development for cancer treatment

Understanding the components that control cell division is fundamental to understanding how life works and how alterations in this delicate process can cause diseases such as cancer. It was precisely the discoveries of “key regulators of the cell cycle” and…

IIVS to collaborate with RIFM to develop non-animal technologies for respiratory allergy

The Institute for In Vitro Sciences (IIVS) and the Research Institute for Fragrance Materials (RIFM) announce a collaboration to develop a non-animal ( in vitro ) test designed to assess potential respiratory allergens. Environmental, consumer, or workplace exposure to respiratory…