Air pollution has been shown to have a negative effect on the prognosis of ischemic stroke, or stroke caused by reduced blood flow to the brain, but the exact mechanism is unknown. A team of researchers recently conducted a study to determine whether or not increased inflammation of the brain, also known as neuroinflammation, is the main culprit.
Tag: NEUROCHEMISTRY
Waste coffee grounds could someday help detect brain waves
There’s nothing like a cuppa to give your morning a boost. Researchers report the first use of waste coffee grounds as electrode coatings for sensitive neurochemistry measurements, which could help scientists get a better handle on brain activity. They will present their results at ACS Spring 2022.
Neuroscientists posit that brain region is a key locus of learning
Small and seemingly specialized, the brain’s locus coeruleus (LC) region has been stereotyped for its outsized export of the arousal-stimulating neuromodulator norepinephrine. In a new paper and with a new grant from the National Institutes of Health, an MIT neuroscience…
‘Feel good’ brain messenger can be willfully controlled, new study reveals
Neuroscientists show that mice can learn to manipulate random dopamine impulses for reward
Investigational magnetic device shrinks glioblastoma in first-in-world human test
Houston Methodist Neurological Institute researchers from the department of neurosurgery shrunk a deadly glioblastoma tumor by more than a third using a helmet generating a noninvasive oscillating magnetic field that the patient wore on his head while administering the therapy…
Scientists reverse age-related memory loss in mice
Scientists at Cambridge and Leeds have successfully reversed age-related memory loss in mice and say their discovery could lead to the development of treatments to prevent memory loss in people as they age. In a study published today in Molecular…
Mechanisms to separately regulate synaptic vesicle release and recycling
Interactions of two voltage-gated calcium channels and a pump enable separate control of exocytosis and endocytosis at chemical synapses
First 3D simulation of rat’s complete whisker system acts as a tactile ‘camera’
Model gives rare insight into how rats use whiskers to actively sense their natural environments
New theory suggests blood immune and clotting components could contribute to psychosis
A scientific review has found evidence that a disruption in blood clotting and the first line immune system could be contributing factors in the development of psychosis. The article, a joint collaborative effort by researchers at RCSI University of Medicine…
Hydrogel composite developed to help protective gear rapidly degrade toxic nerve agents
Scientists at Northwestern University in Evanston, Illinois have developed a hydrogel integrated with zirconium-based robust metal-organic frameworks (MOFs) that rapidly degrades organophosphate-based nerve agents used in chemical warfare. Unlike existing powdered MOF adsorbents, this hydrogel composite does not require added…
Long-term memory setup requires a reliable delivery crew
Synaptic plasticity depends on molecular hauler KIF5C, carrier of more than 650 RNAs, study finds
A Trojan horse could help get drugs past our brain’s tough border patrol
Sclerosis, Parkinson’s Disease, Alzheimer’s and epilepsy are but a few of the central nervous system disorders. They are also very difficult to treat, since the brain is protected by the blood-brain barrier. The blood-brain barrier works as a border wall…
Technology that restores the sense of touch in nerves damaged as a result of injury
Cut your finger and lost your sense of touch? There’s hope yet
New study supports medical safety of electroconvulsive therapy (ECT)
Research may help to address prejudice and discrimination associated with well-established mental health treatment
UCPH researchers prove powerhouse malfunction as the major cause of Parkinson’s Disease
12,000 people in Denmark and 7 to 10 million people worldwide suffer from Parkinson’s Disease (PD). It is the second most common neurogenerative disorder of aging and the most common movement disorder, but the cause of the disease is largely…
An astounding find reveals a rare cause of epilepsy
Researchers at The University of Queensland, working to gain a better understanding of how brain cells work, have discovered the underlying mechanism of a rare genetic mutation that can cause epilepsy. Dr Victor Anggono from UQ’s Queensland Brain Institute said…
Significant increase in impact factor ratings for Bentham Science journals
Clarivate has recently published the latest edition of Journal Citation Reports® providing information for the category ranking and Impact Factor ratings of the indexed journals in 2020. Bentham Science journals have performed well and received outstanding Impact Factor rankings this…
Work like a dream: new anticholinergic drug keeps PTSD flashbacks and nightmares away
Researchers find that central anticholinergic drug trihexyphenidyl can potentially keep away post-traumatic stress disorder-related flashbacks and nightmares
Doctors warn against off-label use of new Alzheimer’s drug for cerebral amyloid angiopathy
There is no clinical evidence that the monoclonal antibody aducanumab is beneficial to patients with cerebral amyloid angiopathy, according to officers with the International Cerebral Amyloid Angiography Association.
Novel technique decodes mechanisms controlling executive functions of the primate brain
Researchers devise a new technique to identify specific neural pathways involved in executive functions of the brain
New solution for sleep apnoea
Existing medications can reduce severity by ‘at least 30%’
Beckman neuroscientists uncover neuronal circuitry controlling auditory sensory perception
A team of neuroscientists at the Beckman Institute for Advanced Science and Technology discovered a new neuronal circuit that may help control which sensory information is relayed to the auditory cortex
Glial cells help mitigate neurological damage in Huntington’s disease
The brain is not a passive recipient of injury or disease. Research has shown that when neurons die and disrupt the natural flow of information they maintain with other neurons, the brain compensates by redirecting communications through other neuronal networks.…
Close-up look at brain uptake of omega-3
SINGAPORE, 17 June 2021 – New details on the structure and function of a transport protein could help researchers develop drugs for neurological diseases that are better able to cross the blood-brain barrier. The findings were published in the journal…
Reduced-dose gadobutrol vs standard-dose gadoterate for contrast-enhanced brain MRI
A 25% reduced gadobutrol dose demonstrated non-inferior efficacy versus 100%-standard dose of gadoterate for contrast-enhanced brain MRI, particularly in patients undergoing multiple contrast-enhanced examinations
Omega-3s may hold key to unlocking blood-brain barrier
NEW YORK, NY (June 16, 2021)–Spectacular images of a molecule that shuttles omega-3 fatty acids into the brain may open a doorway for delivering neurological therapeutics to the brain. “We’ve managed to obtain a three-dimensional structure of the transporter protein…
UChicago scientists identify properties that allow proteins to strengthen under pressure
A new rubber band stretches, but then snaps back into its original shape and size. Stretched again, it does the same. But what if the rubber band was made of a material that remembered how it had been stretched? Just…
New treatment stops progression of Alzheimer’s disease in monkey brains
A new therapy prompts immune defense cells to swallow misshapen proteins, amyloid beta plaques and tau tangles, whose buildup is known to kill nearby brain cells as part of Alzheimer’s disease, a new study shows. Led by researchers at NYU…
Two decade analysis of African neuroscience research prompts calls for greater support
With the world’s largest human genetic diversity, experts believe Africa is vital to help progress neuroscience research
Investigators examine brain tests of patients with COVID-19
In a Journal of Neuroimaging analysis of data obtained from 193 patients with COVID-19 who had brain and/or spine imaging and a lumbar puncture because of neurologic symptoms, investigators found that imaging results were related to the presence of SARS-CoV-2…
Nintendo® wii may help improve balance in children with cerebral palsy
Therapy based on the Nintendo® Wii Balance Board can help improve balance in children with cerebral palsy, according to an analysis published in Developmental Medicine & Child Neurology . For the analysis, researchers from the University of Jaén, in Andalusia,…
Low doses of “laughing gas” could be fast, effective treatment for severe depression
In a phase 2 clinical trial, researchers found a one-hour inhalation session with 25% nitrous oxide gas improved depression symptoms for over two weeks
A drug from resin to combat epileptic seizures
New molecules, developed by researchers at Linköping University, have promising properties as possible drugs against epilepsy. A study published in the journal Epilepsia shows that several of the molecules have antiseizure effects. In people with epilepsy, the nerve cells in…
Cell Reports publishes data supporting the importance of ion channel, Kv7.2/7.3 as a target in ALS
Data supports QurAlis’ approach to treat hyperexcitability induced neurodegeneration in ALS patients; QurAlis gears up for clinical development of therapeutic candidate, QRL-101
Researchers identify a molecule critical to functional brain rejuvenation
The discovery could have important implications for the health of aging brains and development of therapies for neurodegenerative diseases
New study further advances the treatment of chronic pain
LIH and RTI International put forward the mode of action of natural painkiller conolidine, and develop new molecule with enhanced pharmacological properties
Elevating African cichlid fish as a scientific model of social disorders
University of Houston researcher wins prestigious Beckman Young Investigator Award
Protecting the intellectual abilities of people at risk for psychosis
A UNIGE team has found that a class of drugs can protect the development of intellectual abilities in people at risk of psychosis, if prescribed before adolescence
Duetting songbirds ‘mute’ the musical mind of their partner to stay in sync
There’s Simon and Garfunkel, Tina and Ike, and Armstrong and Fitzgerald. But now, nature’s famed duet singers, the plain-tail wren, shows neurobiologists the magic between collaborative performers sparks when music-making parts of the brain go silent.
Brain injury research to focus on moderate concussion
$2.3 million renewal grant to UC Riverside will support a five-year project
Discovery may point to Parkinson’s disease therapies
University of Guelph researchers have discovered a key way Parkinson’s disease spreads in the brain
Novel approaches in treating neurodegenerative disorders
The central nervous system (CNS) is the most vital component of our body, regulating various kinds of daily activities that are essential for our life processes. Keeping the balance between body and brain and maintaining the homeostasis of CNS is…
This brain circuit signals when to stop eating; could regulating it help with obesity
Like a good story, feeding has a beginning, a middle and an end. It begins with appetite prompting the search for food, continues with eating the food and it ends when satiation hits and the consumption of food is stopped.…
University of Kentucky researchers discover fundamental roles of glucosamine in brain
LEXINGTON, Ky. (May 26, 2021) – Using novel imaging methods for studying brain metabolism, University of Kentucky researchers have identified the reservoir for a necessary sugar in the brain. Glycogen serves as a storage depot for the sugar glucose. The…
Vitamin B6 deficiency enhances the noradrenergic system, leading to behavioral deficits
Schizophrenia is a heterogeneous psychiatric disorder characterized by positive symptoms such as hallucinations and delusions, negative symptoms such as apathy and lack of emotion, and cognitive impairment. We have reported that VB6 (pyridoxal) levels in peripheral blood of a subpopulation…
Building a better LED bulb
UH researchers’ new prototype LED lightbulb emits less of that troublesome blue light
ALS Research Partnership Showing Promising Results
Research on a potential therapy for amyotrophic lateral sclerosis (ALS) that’s taking place in a University at Albany chemistry lab is showing promising results.
Specialized inhibitory cluster gates plasticity in fear learning
Has your heart ever started to race at the thought of an upcoming deadline for work? Or has the sight of an unknown object in a dark room made you jump? Well, you can probably thank your amygdala for that.…
3D visualization of oxytocin and vasopressin circuits with unprecedented resolution
Alterations in these circuits may underlie mental disorders characterized by deficits in social interaction, such as autism, social anxiety and aggression, or schizophrenia.
Making the gray cells happy
Neutrons show a connection between lithium concentrations in the brain and depression