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UrduReston, VA–A new radiotracer that detects iron in cancer cells has proven effective, opening the door for the advancement of iron-targeted therapies for cancer patients. The radiotracer, 18F-TRX, can be used to measure iron concentration in tumors, which can help…
Tag: Diagnostics
Early antiviral response in the nose may determine the course of COVID-19
Cells sampled at the time of diagnosis from patients who later developed severe COVID-19 show a muted antiviral response, study finds
MRI, clear cell likelihood score correlate with renal mass growth rate
Standardized non-invasive clear cell likelihood score–derived from MRI–correlates with the growth rate of small renal masses and may help guide personalized management
Artificial intelligence models to analyze cancer images take shortcuts that introduce bias
New study of artificial intelligence tools that analyze tumor images shows how they can make inaccurate predictions based on the institution that submitted the image
Thumb-sized device quickly ‘sniffs out’ bad breath
No one wants bad breath — not when visiting friends and family, at a job interview, and especially not on a first date. Smelly breath can make things awkward, but it also is a natural warning sign, indicating that serious…
Risk score with 6 routinely available lab tests accurately predicts kidney failure
Researchers developed a new risk equation, based on six routinely available patient parameters, that yielded improved performance in estimating the risk of a chronic kidney disease (CKD) patient to progress to end-stage kidney disease (ESKD) requiring kidney replacement therapy (KRT).…
Most studies of acute kidney injury are flawed due to non-use of standard definitions
In an article published in the American Journal of Kidney Diseases (AJKD), researchers found that among 176 studies on acute kidney injury, the Kidney Disease Improving Global Outcomes (KDIGO) definitions of kidney injury were inconsistently applied and 80% of studies…
From birth control to mammograms, many women missed out on preventive care for all of 2020
Study shows even after in-person care restarted, women were 20% to 30% less likely to get such services than in 2019, especially those from lower-income and higher-minority areas
Routine screening for BI-RADS lesions on automated whole-breast ultrasound
Return to routine screening for BI-RADS 3 lesions on supplemental automated whole-breast ultrasound substantially reduces the recall rate, while being unlikely to result in adverse outcome
Glaucoma test ‘best yet’
15-times more likely to detect high risk patients
Wearable sensors with wide-ranging strain sensitivity
Researchers draw inspiration from snake skin in sensor’s structural design
Limiting incident NA for efficient wavefront shaping through thin anisotropic scattering media
A team of researchers, affiliated with UNIST has succeeded in developing a new optical microscope technology, capable of deeper imaging beyond the biological tissues. This breakthrough has been led by Professor Jung-Hoon Park and his research team in the Department…
Short chain fatty acids: An ‘ace in the hole’ against SARS-CoV-2 infection
Scientists find that short chain fatty acids can be used to reduce susceptibility to SARS-CoV-2 infection and mortality from COVID-19
Keeping the world up to date on irritable bowel syndrome research in China
Scientists condense Chinese studies over the past decade on this common gastrointestinal disorder in a review article
Taming the Huntington’s disease proteome: Mass spectrometry may provide answers
Mass spectrometry has helped identify potential biomarkers and new treatment targets for Huntington’s disease report scientists in the Journal of Huntington’s Disease who reviewed 20 years of published studies
Novel screening approach improves diagnosis of metabolic disorders in newborns
A team led by researchers at Baylor College of Medicine found that a screening method known as untargeted metabolomics profiling can improve the diagnostic rate for inborn errors of metabolism, a group of rare genetic conditions, by about seven-fold when…
MRI can cut overdiagnoses in prostate-cancer screening by half
Most countries have not introduced nationwide prostate-cancer screening, as current methods result in overdiagnoses and excessive and unnecessary biopsies. A new study by researchers at Karolinska Institutet in Sweden, which is published in The New England Journal of Medicine ,…
Reduced vs. standard CT dose for lung nodules in children, young adults with cancer
Reduced-dose CT depicts greater than 90% of lung nodules in children and young adults with cancer, identifying the presence of nodules with moderate sensitivity and high specificity
Newborn screening for epilepsy in sight through the discovery of novel disease biomarkers
The door has finally opened on screening newborn babies for pyridoxine-dependent epilepsy (PDE), a severe inherited metabolic disorder. This screening promises to enable better and earlier treatment of the disease. To identify new biomarkers that can be used in the…
Total-body PET imaging exceeds industry standards
Reston, VA–A performance evaluation of the uEXPLORER total-body PET/CT scanner showed that it exhibits ultra-high sensitivity that supports excellent spatial resolution and image quality. Given the long axial field of view (AFOV) of the uEXPLORER, study authors have proposed new,…
Study sheds light on mechanism of liposome accumulation in tumors
CU Cancer Center researcher says results could impact how we diagnose, monitor, and treat tumors with liposomes.
Artificial intelligence provides faster diagnosis for debilitating blistering disease
Scientists at the University of Groningen have trained an Artificial Intelligence system to recognize a specific pattern in skin biopsies of patients with the blistering disease epidermolysis bullosa acquisita. The pattern is characteristic of a specific variant of the disease…
Understanding frailty will lead to better care for older adults
Frailty is a better predictor than factors such as age when determining how older adults fare one year after receiving critical care. A team led by researchers from the University of Waterloo analyzed data from more than 24,000 community-dwelling older…
The shape of nanoparticles in body fluids may help identify the type of cancer
A recent study by scientists from Japanese universities has shown that the shape of cell-derived nanoparticles, known as “extracellular vesicles” (EVs), in body fluids could be a biomarker for identifying types of cancer. In the study, the scientists successfully measured…
Research paves the way to early diagnosis of diabetic neuropathy
Diabetics exert less force to hold an object than people with other diseases that affect the nervous system. Grip force is a key behavioral biomarker to detect incipient diabetic neuropathy
Molecular imaging improves staging and treatment of pancreatic ductal adenocarcinomas
Reston, VA–For patients with pancreatic ductal adenocarcinomas (PDAC), molecular imaging can improve staging and clinical management of the disease, according to research published in the June issue of The Journal of Nuclear Medicine . In a retrospective study of PDAC…
NIH Avant Garde Award for Out-Of-Box, Innovative Concept to Cure HIV and Treat Addiction
Multi-Disciplinary Approach to Eradicate All Traces of HIV from Body, and Treat Co-existing Substance Use Disorders/Addiction
SARS-CoV-2 encoded miRNA is a biomarker for stratification of severe patients
In a retrospective, multi-centre cohort study conducted by researchers from Nanjing University, Huazhong University of Science and Technology, Jinling Hospital and the Second Hospital of Nanjing, a microRNA-like small RNA encoded by SARS-CoV-2 was identified in the serum of COVID-19…
New clinical indicators discovered in transplant patients with COVID-19
Elisa Cordero, a doctor at the Virgen del Rocío University Hospital, researcher at the Institute of Biomedicine of Seville (IBiS) and professor in the Department of Medicine at the University of Seville, led a study involving researchers from 12 Spanish…
Blood test for personalized cancer treatment
A blood test to help guide the treatment of oesophageal, stomach and bowel cancers will be evaluated in a new Flinders University trial set to get underway. The trial is thanks to a federal government grant of almost $2 million…
Hi-tech lab to boost COVID-19 diagnostic capability, prepare for future pandemics
Singapore, 1 July 2021 – Nanyang Technological University, Singapore (NTU Singapore) and Pathnova Laboratories, a medical diagnostic company backed by Temasek Life Sciences Accelerator and headquartered in Temasek Life Sciences Laboratory, is contributing to Singapore’s COVID-19 diagnostic capability through its…
UCLA scientists say COVID-19 test offers solution for population-wide testing
More than 80,000 tests done in under two months
‘Genomics of Rare Diseases. Understanding Disease Genetics Using Genomic Approaches’
In 2018, Dr. Claudia Gonzaga-Jáuregui, who years before had completed her doctorate studies in Dr. James R. Lupski’s lab at Baylor College of Medicine, received an email from an editor at Elsevier’s Academic Press with a proposal that immediately caught…
State of the art and future directions in the clinical application of HR-pQCT in adults
A new international guidance on the clinical application of high-resolution peripheral computed tomography (HR-pQCT) offers an important overview of current clinical applications in adults and direction on the interpretation of results
Prototype may diagnose common pregnancy complications by monitoring placental oxygen
NIH researchers pursue innovative method for observing maternal and fetal health during pregnancy
Foresight diagnostics to show vision of the new standard of lymphoma MRD detection at ICML
AURORA, COLORADO, June 16, 2021 — Foresight Diagnostics, the emerging leader in blood-based lymphoma disease monitoring, announced today that clinical performance of its minimal residual disease (MRD) detection platform in diffuse large B-cell lymphoma (DLBCL) will be presented at the…
Reduced-dose gadobutrol vs standard-dose gadoterate for contrast-enhanced brain MRI
A 25% reduced gadobutrol dose demonstrated non-inferior efficacy versus 100%-standard dose of gadoterate for contrast-enhanced brain MRI, particularly in patients undergoing multiple contrast-enhanced examinations
Study validates a highly sensitive molecular test to detect cases of Tubercul
The results confirm that the ‘Xpert Ultra’ is a frontline tool in routine conditions and is effective in different contexts
Simple urine test may help early detection of brain tumors
A recent study by Nagoya University researchers revealed that microRNAs in urine could be a promising biomarker to diagnose brain tumors. Their findings, published in the journal ACS Applied Materials & Interfaces , have indicated that regular urine tests could…
Concordia researchers break down the COVID-19 diagnostic arsenal
Hamid Tali and Sana Anbuhi comb the growing pile of literature for the tools and techniques that best detect the virus
SNMMI Image of the Year: PET imaging measures cognitive impairment in COVID-19 patients
Reston, VA–The effects of COVID-19 on the brain can be accurately measured with positron emission tomography (PET), according to research presented at the Society of Nuclear Medicine and Molecular Imaging (SNMMI) 2021 Annual Meeting. In the study, newly diagnosed COVID-19…
Novel radiotracer shows promise to predict abdominal aortic aneurysm rupture
Reston, VA (Embargoed until 6:15 p.m. EDT, Tuesday, June 15, 2021)–A new positron emission tomography (PET) radiotracer can detect abdominal aortic aneurysms (AAAs) and potentially predict when they will rupture, according to research presented at the Society of Nuclear Medicine…
PSMA-targeted radiotracer pinpoints metastatic prostate cancer across anatomic regions
Newly FDA-approved imaging agent now available for patients
Postop chylothorax treated with intranodal lymphangiography, ethiodized oil
High-dose intranodal lymphangiography with ethiodized oil is a safe and effective procedure for treating high-output postsurgical chylothorax with chest tube removal in 83% of patients
A new model of Alzheimer’s progression
Alzheimer’s disease is the most common form of dementia and is characterized by neurodegeneration in regions of the brain involved in memory and learning. Amyloid beta and tau are two toxic proteins that build up in disease and cause eventual…
New theranostic approach joins radiopharmaceuticals and nanoparticles to kill cancer cells
Reston, VA (Embargoed until 12:30 p.m. EDT, Monday, June 14, 2021) – Researchers have successfully developed a novel cancer treatment approach that utilizes Cerenkov radiation energy to target and destroy cancer cells more effectively. The approach uses light from decaying…
Steven M. Larson, M.D., receives SNMMI 2021 Paul C. Aebersold Award
Larson recognized for for outstanding achievement in basic nuclear medicine science
Society of Nuclear Medicine and Molecular Imaging announces 2021 Fellows
Reston, VA (Embargoed until 11:00 am, Monday, June 14, 2021)- The Society of Nuclear Medicine and Molecular Imaging recognized 17 new SNMMI Fellows on Monday, June 14, during a plenary session at the society’s 2021 Annual Meeting, held virtually June…
Thomas J. Ruth, Ph.D., FRSC, FSRS, Receives SNMMI de Hevesy Nuclear Pioneer Award
Reston, VA (Sunday, June 13, 2021)–Thomas J. Ruth, PhD, FRSC, FSRS, a scientist known for his contributions to nuclear medicine and nuclear chemistry, has been named as this year’s recipient of the Georg Charles de Hevesy Nuclear Pioneer Award. Ruth…
Touchless technology could enable early detection and treatment of eye diseases that cause blindness
A non-contact laser imaging system could help doctors diagnose and treat eye diseases that cause blindness much earlier than is now possible. The new technology, developed by engineering researchers at the University of Waterloo, is designed to detect telltale signs…