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UrduScientists have developed a ‘nanobody’ – a small fragment of a llama antibody – that is capable of chasing out human cytomegalovirus (HCMV) as it hides away from the immune system. This then enables immune cells to seek out and…
Tag: DISEASE IN THE DEVELOPING WORLD
CEPI and IVI collaborate on clinical research to expand access to COVID-19 vaccines in Africa
July 20, 2021; Oslo, Norway and Seoul, Republic of Korea: The Coalition for Epidemic Preparedness Innovations (CEPI) and the International Vaccine Institute (IVI) today announced a new programme of clinical research which aims to expand access to COVID-19 vaccines in…
Study refutes suspicion that dengue increases risk of microcephaly associated with zika
Researchers compared data for pregnant women in two cities who were infected by zika virus in 2015-16. Factors that influenced the risk of fetal malformation were the high zika attack rate in the area and being infected in the first trimester of pregnan
Most studies of acute kidney injury are flawed due to non-use of standard definitions
In an article published in the American Journal of Kidney Diseases (AJKD), researchers found that among 176 studies on acute kidney injury, the Kidney Disease Improving Global Outcomes (KDIGO) definitions of kidney injury were inconsistently applied and 80% of studies…
The seeds that give: retired WVU plant pathologist donates tomato seeds to developing nations
Mannon Gallegly, professor emeritus of plant pathology at West Virginia University, is donating tomato seeds to the World Vegetable Center, a global nonprofit institute for vegetable research and development.
CNIO researchers clarify the role of the two isoforms of KRAS, the most common oncogene in humans
These findings suggest that for therapies to be effective, they must be targeted at both gene products
Occurrence of young-onset dementia
What The Study Did: This study included a meta-analysis that combined the results of 74 studies with 2.7 million participants to estimate how common globally dementia is in people younger than age 65. Authors: Sebastian Köhler, Ph.D., of Maastricht University…
Evaluation of India’s ‘Mission Indradhanush’ finds improvements in vaccination outcomes
Researchers at CDDEP evaluated the performance of India’s Mission Indradhanush (MI) child vaccination campaign to find an increase in vaccination rates and timeliness of vaccination.
Study finds vaccine hesitancy lower in poorer countries
New study examines vaccine acceptance and hesitancy in 10 low- and middle-income countries in Asia, Africa, and South America
Measures and clinical approach of COVID 19
The coronavirus disease 2019 (COVID-19) outbreak has spread throughout the globe and much time has passed since it was declared as a pandemic by the World Health Organization (WHO). COVID-19: Diagnosis and Management provides clinicians and scholars all the information…
GARDP, CHAI and Shionogi announce MOU to increase access to antibiotic
The Global Antibiotic Research and Development Partnership (GARDP), the Clinton Health Access Initiative (CHAI) and Shionogi & Co., Ltd today announced a Memorandum of Understanding (MOU) to accelerate access, including in low- and middle-income countries, to the antibiotic cefiderocol for…
COVID-19 hospitalization and mortality: Sex differences
New Rochelle, NY, July 13, 2021–Males with COVID-19 had significantly higher rates of hospitalization and of transfer to the intensive care unit (ICU) according to a new study. A higher percentage of males died of COVID-19 compared to females, as…
Urban areas with high levels of air pollution may increase risk of childhood obesity
A study of more than 2,000 children in Sabadell (Barcelona, Spain) associates these three environmental factors with higher body mass index
Nearly 8% of men who have sex with men estimated to have syphilis globally
Syphilis prevalence 15x higher than men in the general population
‘Smart collar’ could prevent tapeworms in dogs
Dogs infected with echinococcosis play a major role in spreading tapeworms across human populations around the world. Now, researchers have developed a “smart collar” which gradually delivers a steady dose of a deworming drug to dogs. The collar successfully reduces…
Packaged water consumption linked to cholera outbreak in DRC capital
Cholera is a diarrheal disease caused by ingestion of the Vibrio cholerae bacterium. In November 2017, a cholera epidemic occurred in Kinshasa, the Democratic Republic of the Congo, where no outbreak had been recorded for nearly a decade. A study…
Why wild African fruits can supplement low protein staple foods
In the line-up of wild African fruits, the marula is the best known. For thousands of years, people have depended on the trees for food, medicines, and more. It is also exported globally as the rockstar ingredient of a cream…
Wolbachia and the paradox of growth regulation
A genetic approach offers new clues to the regulation of Wolbachia proliferation and the effect of over-proliferation on the insect hosts.
Malaria and dengue predicted to affect billions more people
New modelling study reinforces the importance of reducing emissions and increasing surveillance in potential ‘hotspot’ areas
Global health scientist named fellow of prestigious international informatics organization
INDIANAPOLIS — Regenstrief Research Scientist and Indiana University School of Medicine Associate Professor Paul Biondich, M.D., M.S., has been elected as a 2021 fellow of the International Academy of Health Sciences Informatics (IAHSI). The Academy is a group of health…
Eight new studies to investigate COVID-19 variants of concern in Canada
The research projects span from investigating the social factors that may protect Indigenous peoples — or increase their vulnerability to — COVID-19 and VOCs, to the creation of a Canadian Wastewater Surveillance Database
ACC Asia conference delivers emerging trends for improving heart health
Partnering with the Singapore Cardiac Society, ACC Asia 2021 moves into era of global collaboration in cardiovascular prevention and care
Leaders’ pandemic policies engendered varying levels of trust
As the COVID-19 pandemic exploded across the globe in early 2020, the world’s leaders were faced with a flurry of tough moral dilemmas. Should schools and businesses shut down, and if so, for how long? Who should receive scarce resources,…
Personal networks are associated with clean cooking fuel adoption in rural South India
Study led by Boston College researchers is the first to examine role of peer networks in ‘clean cooking’ public health initiatives
‘Genomics of Rare Diseases. Understanding Disease Genetics Using Genomic Approaches’
In 2018, Dr. Claudia Gonzaga-Jáuregui, who years before had completed her doctorate studies in Dr. James R. Lupski’s lab at Baylor College of Medicine, received an email from an editor at Elsevier’s Academic Press with a proposal that immediately caught…
Demystifying COVID-19
In this book ‘Demystifying COVID-19- understanding of the Disease, its diagnosis and treatment’ basic points are discussed from case examples to the main principles followed in diagnosis and treatment, real scenarios in the course of the disease, issues that need…
Thrombosis in cancer
Ever since the association between cancer and thrombosis was reported by Jean-Baptiste Bouillaud in the early 19th century, cancer-associated thrombosis has remained a challenging domain of cancer management. Thrombosis can at times be a lead to cancer diagnosis, while it…
Clinical and pre-clinical antimicrobial drug development
This book series brings updated reviews to readers interested in advances in the development of anti-infective drug design and discovery. It covers a range of topics including rational drug design and drug discovery, medicinal chemistry, in-silico drug design, combinatorial chemistry,…
The paths through which COVID-19 spread across Brazil
The impact of super-spreader cities, highways, and intensive care availability in the early stages of the COVID-19 epidemic in Brazil
“Smart” segmented ring device delivers medications to stop HIV transmission
Researchers have designed a device that delivers two medications that help stop HIV transmission. Although condom usage is the best strategy for preventing HIV transmission, the researchers are working to design a device that can be used by sex workers…
Children with asymptomatic malaria a ‘hidden risk’ to disease control efforts
Study in Uganda highlights potential for school-aged children to be targeted for malaria control interventions
UMSOM researchers work to improve use of genetic risk scores in diverse populations
Research will expand database to include under-represented minority populations to make risk scores more predictive and reliable for clinical use
Liver cancer call for help
Indigenous communities missing care — expert
Air pollution exposure during pregnancy may boost babies’ obesity risk
Women exposed to higher levels of air pollution during pregnancy have babies who grow unusually fast in the first months after birth, putting on excess fat that puts them at risk of obesity and related diseases later in life, new…
Microscopic CCTV reveals secrets of malaria invasion
State-of-the-art video microscopy has enabled researchers at WEHI, Australia, to see the molecular details of how malaria parasites invade red blood cells – a key step in the disease. The researchers used a custom-built lattice light sheet microscope – the…
Common cold combats COVID-19
Exposure to the rhinovirus, the most frequent cause of the common cold, can protect against infection by the virus which causes COVID-19, Yale researchers have found. In a new study, the researchers found that the common respiratory virus jump-starts the…
Malaysia registers first hepatitis C treatment developed through South-South cooperation
New treatment combination for hepatitis C virus (HCV) is an additional affordable option for millions still waiting for access to lifesaving treatments in middle-income countries
A novel tuberculosis regimen shortens treatment course for patients
Researchers at the Medical University of South Carolina and elsewhere find a new antibiotic regimen that shortens the treatment course for patients with tuberculosis
A missing antibody molecule may indicate when dengue will become deadly
A first encounter with the dengue virus typically causes very mild symptoms; however, a subsequent infection is a different story. For a small proportion of people who are reinfected, the virus can cause severe symptomatic disease, which is often life-threatening.…
Centivax and US Naval Medical Research Center announce strategic partnership
Initiate clinical development of a broad-spectrum injectable for COVID-19, with $4.2M from the Henry Jackson Foundation
How HIV infection shrinks the brain’s white matter
Researchers from Penn and CHOP detail the mechanism by which HIV infection blocks the maturation process of brain cells that produce myelin, a fatty substance that insulates neurons
Future Pandemic? Consider Radically Altering Animal Agriculture Practices
FAU Bioethicist Offers Plausible Solutions to Mitigate Zoonotic Risk from Agriculture and Food Production for Public Health
Global research team develops fine-scale risk maps to tackle malaria in Haiti
Researchers from Telethon Kids Institute and Curtin University in Perth and Tulane University in New Orleans have developed sophisticated data modelling that could help eradicate malaria in Haiti. Haiti is the poorest country in the Caribbean – beset by natural…
Seeds of economic health disparities found in subsistence society
PULLMAN, Wash. – No billionaires live among the Tsimane people of Bolivia, although some are a bit better off than others. These subsistence communities on the edge of the Amazon also have fewer chronic health problems linked to the kind…
Global costs of Plasmodium vivax malaria estimated for the first time
Plasmodium vivax malaria is a mosquito-borne illness that causes significant morbidity. However, the household and healthcare provider costs of the disease are unknown. A new study published in the open-access journal PLOS Medicine by Dr Angela Devine at Menzies School…
Malaria parasite’s partiality for the spleen
The malaria parasite Plasmodium vivax may accumulate in the spleen soon after infection to a greater extent than its better-known relative P. falciparum, according to new research published by John Woodford of the University of Queensland, Brisbane, Australia and colleagues…
Parasites may accumulate in spleens of asymptomatic individuals infected with malaria
Study suggests immature red blood cells in spleen are targeted for invasion by P. vivax
Scientists develop novel therapy for crimean-congo hemorrhagic fever virus
Army scientists working as part of an international consortium have developed and tested an antibody-based therapy to treat Crimean-Congo hemorrhagic fever virus (CCHFV), which is carried by ticks and kills up to 60 percent of those infected. Their results are…
Analysis reveals global ‘hot spots’ where new coronaviruses may emerge
Forest fragmentation, agricultural expansion and concentrated livestock production in China and Southeast Asia are bringing humans into closer contact with bats known to carry zoonotic diseases
Lundquist investigators in global study expanding genomic research of different ancestries
Paper in Nature Genetics: Genome-wide meta-analysis shows that research into different ancestries leads to better results and better care