Researchers at UC San Diego School of Medicine find that limiting food consumption within a 10-hour window each day improved key markers of heart health.
Tag: Type 2 Diabetes
Alarming Surge: Global Crisis of Childhood Overweight and Obesity
Since 1990, childhood obesity has nearly doubled globally, with the U.S. at the forefront. In Southern Europe, 10-15% of children are obese, while Asia has nearly half of all overweight kids under 5. Nearly 70% of the average U.S. child’s diet consists of ultra-processed foods, which are increasingly consumed by children under 24 months, raising obesity risks and reducing immunological protection. Addressing pediatric obesity requires a multifaceted approach from tackling the influence of social media and advertising on children’s food choices to increasing physical activity.
Could GLP1RA drugs lower high iron levels?
GLP1RA agonists have been increasing in popularity for treating obesity and type 2 diabetes. With this novel treatment proving to be very effective, researchers are curious to know more about what other potential treatments it could also hold.
UNDER EMBARGO: Mount Sinai Study Identifies Link Between Prediabetes During Adolescence and Young Adulthood With the Likelihood of Adverse Pregnancy Outcomes
New paper finds that prediabetes before conception may significantly increase the likelihood of gestational diabetes during first pregnancy
The hidden health risks of styrene and ethylbenzene exposure
A recent study conducted by the Department of Occupational and Environmental Health at Tongji Medical College, Huazhong University of Science and Technology, reveals a strong link between exposure to styrene and ethylbenzene, common air pollutants, and an increased risk of developing type 2 diabetes mellitus (T2DM).
Research assesses impact of weight loss and blood sugar control in Type 2 Diabetes
A Cleveland Clinic research team has published the first study assessing the independent real-world impacts of weight loss and blood sugar control on clinical outcomes in people with type 2 diabetes treated with antidiabetic medications, and specifically with GLP-1RAs (the…
Moderate coffee and caffeine consumption is associated with lower risk of developing multiple cardiometabolic diseases, new study finds
Consuming moderate amounts of coffee and caffeine regularly may offer a protective effect against developing multiple cardiometabolic diseases, including type 2 diabetes, coronary heart disease and stroke, according to new research published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.
Disruptions to Cholesterol in Cells Is an Early Sign of Beta Cell Damage in Model of Type 2 Diabetes
Article title: Dysregulation of cholesterol homeostasis is an early signal of beta cell proteotoxicity characteristic of type 2 diabetes Authors: Tatyana Gurlo, Ruoshui Liu, Zhongying Wang, Jonathan Hoang, Sergey Ryazantsev, Marie Daval, Alexandra E. Butler, Xia Yang, Montgomery Blencowe, Peter…
Mental health and chronic diabetes complications strongly linked both ways, study finds
When a person has chronic diabetes complications – such as heart attack, stroke and nerve damage – they are more likely to have a mental health disorder, and vice versa, according to a study. Researchers say the findings highlight a need for clinicians to actively screen for mental health disorders in patients with diabetes in addition to screening for chronic complications, which is the recommended standard of care in diabetes.
Type 2 diabetes increased by almost 20% over a decade
Type 2 diabetes increased by almost 20% between 2012 and 2022, according to a new study from the University of Georgia.
Combining Two Diabetes Drugs Helps Promote Weight Loss and Blood Sugar Control
New research finds a combination of drugs improves weight loss, glucose control and insulin resistance better than either drug alone. Using two diabetes medications together, such as a semaglutide like Ozempic or Rybelsus, with a second, newer class of drug, may offer a noninvasive solution to help people with Type 2 diabetes lose weight and manage their condition without the need for bariatric surgery.
The Medical Minute: The truth about diabetes
Type 1? Type 2? Do you have to take injections for the rest of your life? A Penn State Health expert discusses diabetes and how there are more options than ever to beat it.
Seeking Ozempic Alternatives? Prioritize Safety with These Expert Tips
Ozempic is a medication used to treat type two diabetes, often used for weight loss purposes. Its high cost and need for a prescription has led people on the internet to look for cheaper alternatives. There are several such DIY…
Rutgers Names Nationally Recognized Clinician-Scientist in Obesity and Nonalcoholic Fatty Liver Disease as New Chair of Medicine
Jeanne M. Clark, a board-certified internal medicine physician with extensive research experience and a nationally renowned expert in the epidemiology and treatment of obesity, will join Rutgers Robert Wood Johnson Medical School as the Henry Rutgers Professor and chair of the Department of Medicine.
New study shows popular diabetes and weight-loss drugs associated with lower risk for tobacco-use disorder
A new study by researchers at the Case Western Reserve School of Medicine reveals popular diabetes and weight-loss drugs are linked to a lower risk for tobacco-use disorder (TUD) in smokers with type 2 diabetes, compared with seven other anti-diabetes medications.
Semaglutide may show promise for smoking cessation
New use of semaglutide was associated with a lower risk for medical care related to tobacco use disorder (TUD) in smokers with type 2 diabetes compared with 7 other anti-diabetes medications.
American Heart Association Recognizes Loyola University Medical Center for Advanced Care for Stroke and Type 2 Diabetes
Loyola University Medical Center (LUMC) has earned the American Heart Association’s Get With The Guidelines® – Stroke Gold Plus quality achievement award for its commitment to ensuring stroke patients receive the most appropriate treatment according to nationally recognized, research-based guidelines, ultimately leading to more lives saved and reduced disability.
New Cedars-Sinai Study Investigates Shifting Trends in GLP-1RA Prescription
Investigators at Cedars-Sinai and other institutions conducted a nationwide, population-based study to identify trends in the use of glucagon-like peptide-1 receptor agonists (GLP-1RAs)—prescription medications sold under popular drug names like Ozempic and Wegovy—in the United States.
For clinicians, diagnostic criteria for obesity remains elusive
Obesity now affects 2 in 5 U.S. adults, making it one of the most important public health problems facing society. However, finding an accurate way to identify obesity in individuals remains challenging given the very diverse U.S. patient population.
Data shows surge in in new GLP-1RA prescriptions for obesity without type 2 diabetes
A nationwide study found a marked increase in new GLP-1RA prescriptions over the last decade, particularly since 2020. Semaglutide was the most prescribed GLP-1RA, by far, in 2023.
Modification of Common Diabetes Drug Improved Blood Sugar Control in Mouse Model
Article title: Reduced incretin receptor trafficking upon activation enhances glycemic control and reverses obesity in diet-induced obese mice Authors: Rathin Bauri, Shilpak Bele, Jhansi Edelli, Neelesh C. Reddy, Sreenivasulu Kurukuti, Tom Devasia, Ahamed Ibrahim, Vishal Rai, Prasenjit Mitra From the authors: “Chronic…
Continuing metformin during first trimester does not increase risk for major malformations
A study of more than 12,000 pregnant women with type 2 diabetes receiving metformin monotherapy before conception found that compared with switching to insulin monotherapy, continuing metformin and adding insulin in early pregnancy resulted in little to no increased risk for major malformations in the infant.
Physicians debate best management strategy for patient with type 2 diabetes and CKD
In a new Annals ‘Beyond the Guidelines’ feature, an endocrinologist and a nephrologist discuss controversies regarding the care of patients with type 2 diabetes (T2D) and chronic kidney disease (CKD) and how they would apply the consensus statement to the care of an individual patient with T2D who is unaware that he has CKD.
Timing key for type 2 diabetes drug performance
Researchers from the University of Adelaide could be closer to discovering a better way to use metformin, a common type 2 diabetes medication. Metformin, which has been a cornerstone in diabetes treatment since the 1960s, is typically taken with meals to reduce gastrointestinal side effects but new research is suggesting patients could see improved results if it’s taken before meals.
Two medication classes reduced cardiovascular and liver events in people with type 2 diabetes
GLP-1 receptor agonists (GLP-1s) and SGLT-2 inhibitors lower the risk of major cardiovascular events like heart attacks and severe liver complications compared to other diabetes treatments, according to data being presented Sunday at ENDO 2024, the Endocrine Society’s annual meeting in Boston, Mass.
GLP-1 medications for type 2 diabetes and obesity may lower risk of acute pancreatitis
Medications for type 2 diabetes and obesity known as GLP-1 receptor agonists may lower the risk of acute pancreatitis recurrence in people with obesity and those with type 2 diabetes, according to a study presented Saturday at ENDO 2024, the Endocrine Society’s annual meeting in Boston, Mass.
Asian patients more likely to develop type 2 diabetes 1 year after prediabetes diagnosis compared to white and Black patients
One year after a prediabetes diagnosis, Asians were more likely to develop diabetes mellitus whereas Black patients were more likely to remain in prediabetes range, highlighting racial disparities in diabetes prevention, according to data presented at ENDO 2024, the Endocrine Society’s annual meeting in Boston, Mass.
Higher blood concentrations of testosterone are associated with reduced risk of developing type 2 diabetes in men under 65
Testosterone appears protective against developing type 2 diabetes in men who are overweight or obese and under age 65, but not in men over that age, according to a study presented Saturday at ENDO 2024, the Endocrine Society’s annual meeting in Boston, Mass.
Insurance often denies GLP-1 medications for teens with type 2 diabetes, obesity
Health insurance companies often deny coverage for new medications that treat children and teens with obesity and type 2 diabetes, meaning many patients who need treatment are unable to afford it, according to a study presented at ENDO 2024, the Endocrine Society’s annual meeting in Boston, Mass.
Advance in the Treatment of Acute Heart Failure Identified
A multicenter study led by Vanderbilt University Medical Center (VUMC) and Lipscomb University College of Pharmacy in Nashville has identified a potential new treatment for acute heart failure, a leading cause of hospitalization and death.
Intensive Blood Pressure Treatment May Help Some Middle-Aged Women
Investigators in the Smidt Heart Institute at Cedars-Sinai and colleagues report that women with Type 2 diabetes diagnosed with hypertension before age 50 may benefit from intensive blood pressure treatment.
Genetics predict type 2 diabetes risk and disparities in childhood cancer survivors
Learn how ancestry changes genetic risk variants’ impact on type 2 diabetes in childhood cancer survivors & alkylating agent exposure magnifies diabetes risk.
American College of Physicians issues clinical recommendations for newer pharmacological treatments of adults with Type 2 diabetes
A new guideline from the American College of Physicians (ACP) offers clinical recommendations for the use of newer pharmacological treatments of adults with Type 2 diabetes.
This Outdated Diabetes Drug Still Has Something to Offer
Researchers from UC San Diego have discovered the biochemical workings of an old-fashioned diabetes drug, and it’s helping them develop new, safer alternatives.
New study shows effect of socio-economic factors—housing, food, neighborhood—to predict diabetic patients’ risk of heart failure
A recent study by Case Western Reserve University used national data from U.S. military veterans with diabetes to validate and modify a widely accepted model used to predict the risk of heart failure in diabetic patients.
Resistant Starch Could Help Combat Leading Cause of End-stage Kidney Failure
Combining a low dose of blood pressure medication with a higher intake of dietary-resistant starch might help stave off diabetic kidney disease, according to results from a new animal study. Researchers will present their work this week at the American Physiology Summit.
Heavy Alcohol Use May Increase Type 2 Diabetes Risk in Middle-aged Adults
Heavy alcohol use may increase middle-aged adults’ risk of developing Type 2 diabetes, according to research to be presented this week at the American Physiology Summit in Long Beach, California. The Summit is the flagship annual meeting of the American Physiological Society (APS).
L-Nutra’s Groundbreaking Study Revolutionizes Type 2 Diabetes Management Through Fasting Mimicking Nutrition Technology
Today, L-Nutra, the premier nutri-technology company, unveiled the results of a pioneering clinical trial, published in Diabetologia, which aims to redefine the approach to managing Type 2 Diabetes.
Study Shows Bariatric Surgery Provides Superior Long-Term Treatment for Type 2 Diabetes in Patients with Obesity
Research by Cleveland Clinic and three other U.S. medical centers has found that bariatric surgery provides better long-term control of blood glucose levels in patients with obesity and type 2 diabetes, compared with medical therapy.
Insulin resistance in shift workers not affected by melatonin treatment
Melatonin treatment does not affect the insulin resistance or the glucose tolerance of night shift workers, according to a new study from the University of Surrey and the University Medical Centre Hamburg. Melatonin treatment does, however, significantly improve the sleep quality of those working shifts.
Newly discovered genetic markers help pinpoint diabetes risks, complications
UMass Amherst researcher co-leads worldwide efforts to understand how genetic variants are linked with disease to develop new drugs and treatments.
High out-of-pocket costs hindering treatment of diabetes
Diabetes care providers should account for impacts caused by financial insecurity, researchers suggest
Gastric Bypass Improves Long-Term Diabetes Remission, Even After Weight Recurrence
Adults who have obesity and Type 2 diabetes are much more likely to see their diabetes stay in remission if they undergo gastric bypass surgery rather than sleeve gastrectomy, even after regaining weight, according to a study published in the Journal of the American College of Surgeons (JACS).
Type 2 Diabetes Alters the Behavior of Discs in the Vertebral Column
Type 2 diabetes alters the behavior of discs in the vertebral column, making them stiffer, and also causes the discs to change shape earlier than normal.
New weight loss medication may help lower blood pressure in adults with obesity
DALLAS, Feb. 5, 2024 —The new weight loss medication tirzepatide significantly lowered the systolic blood pressure (the top number in a blood pressure reading) for nearly 500 adults with obesity who took the medication for about eight months, according to new research published today in Hypertension, an American Heart Association journal.
Disrupted cellular function behind type 2 diabetes in obesity
Disrupted function of “cleaning cells” in the body may help to explain why some people with obesity develop type 2 diabetes, while others do not.
High insulin levels directly linked to pancreatic cancer
First detailed explanation of why people with obesity and Type 2 diabetes are at an increased risk of pancreatic cancer
Physician Dispels Myths and Shares Insight Ahead of American Diabetes Month
More than 37 million Americans have been diagnosed with diabetes, with another 8.5 million believed to be living with the condition undiagnosed. In addition, 38 percent of the United States adult population is estimated to have prediabetes, a serious condition…
Children with prediabetes and obesity may be more likely to progress to diabetes
A new Journal of the Endocrine Society study highlights how to identify children at high risk of developing type 2 diabetes and strategies for prevention, such as anti-obesity or anti-diabetes medication and lifestyle changes.
Pharmacist-led intervention can improve medication adherence among Latinos with type 2 diabetes
Diabetes control can significantly improve for Latinos when a pharmacist implements an intervention that addresses these patients’ barriers to medication adherence.