Toxicological Sciences delivers the latest toxicology research in the July 2021 issue. The issue features investigations in delivers the latest toxicology research in areas such as exposure to delta-9-tetrahydrocannabinol and cannabidiol, effects of ENDS vapors on amino acid metabolism, and more.
ACSM’s comprehensive sports medicine and exercise science conference takes place virtually from June 1 to 5 with programming covering the science, practice, public health and policy aspects of sports medicine, exercise science and physical activity.
UNC School of Medicine scientists found that HIV boosts a key process in human cells to fuel its replication. They also found that the diabetes drug metformin inhibits that process and thereby suppresses HIV replication in these cells in cell lines and animal models.
Patients whose Type 2 diabetes is not controlled with metformin can benefit long-term from a two-drug combination treatment that also reduces weight.
A new study suggests that treating a breastfeeding parent with a common diabetes drug may provide male offspring lifelong protection against diabetes and obesity. The study is published ahead of print in the American Journal of Physiology-Endocrinology and Metabolism. It was chosen as an APSselect article for May.
Article title: Lactational metformin exposure programs offspring white adipose tissue glucose homeostasis and resilience to metabolic stress in a sex-dependent manner Authors: Zach Carlson, Hannah Hafner, Molly Mulcahy, Kaylie Bullock, Allen Zhu, Dave Bridges, Ernesto Bernal-Mizrachi, Brigid Gregg From the authors: “Future…
UC San Diego researchers use 3D human gut organoids to reveal the molecular system that keeps intestinal linings sealed, demonstrate how the system breaks down and how it can be strengthened with the diabetes drug metformin.
Scientists were surprised when they found out that metformin caused the secretion of GDF15, a protein which is known to suppress appetite.
Two drugs already on the market to treat type two diabetes are being tested in nonhuman primates to see if they can impact the aging process. Researchers dosed marmosets with Metformin and Acarbose and found no adverse side effects