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UrduSix-month outcomes from the randomized RADIANCE-HTN TRIO Trial comparing endovascular ultrasound renal denervation (RDN) to a sham procedure for treatment-resistant hypertension (HTN) found that the addition of a pharmacologic intervention led to further blood pressure reductions after RDN with a smaller increase in additional medications prescribed and less use of diuretics.
Tag: Hypertension
Exercise May Correct Leakage of Blood-brain Barrier Caused by High Blood Pressure
Article title: Transcytosis within PVN capillaries: a mechanism determining both hypertension-induced blood-brain barrier dysfunction and exercise-induced correction Authors: Matheus Garcia Fragas, Vanessa Brito Cândido, Gustavo Gastão Davanzo, Carla Rocha-Santos, Alexandre Ceroni, Lisete C. Michelini From the authors: “The present set…
Elevated stress hormones linked to higher risk of high blood pressure and heart events
Adults with normal blood pressure and high levels of stress hormones were more likely to develop high blood pressure and experience cardiovascular events compared to those who had lower stress hormone levels, according to new research published today in Hypertension, an American Heart Association journal.
Setting the Stage for Controlling Hypertension: New Paper Outlines Study Elements Needed to Address Dietary Contributors to Risk
Carefully designed research is key to understanding the role of the dietary sodium-to-potassium ratio in blood pressure changes
UC San Diego Health Launches New Center to Spur Patient-Centered Technologies
From tele-monitoring patients with diabetes to using artificial intelligence to prevent sepsis, the newly launched Center for Health Innovation will seek to develop, test and commercialize technologies that make a real, measurable difference in the lives and wellbeing of patients.
Genetics Determine Hypertension More in Women Than Men
Researchers from the Smidt Heart Institute suggest that, contrary to common belief, the risk of developing high blood pressure has more to do with genetics in women than in men.
4 in 1 blood pressure pill: safe and much more effective than usual hypertension treatment
The first large-scale, long-term trial of a new strategy using combinations of very low-doses in one capsule, has demonstrated significantly improved control of high blood pressure – the leading cause of heart attack and stroke.
The Lancet: Number of people living with hypertension has doubled worldwide over past 30 years to more than 1.2 billion
Most comprehensive analysis of its kind charting hypertension prevalence, diagnosis, treatment and control in 200 countries over past 30 years reveals more than half of people with hypertension, or 720 million, worldwide were untreated in 2019.
Wayne State receives $2.6 million research award from American Heart Association
Black adults have a higher incidence of hypertension (HTN) and a greater risk of HTN-related cardiovascular disease compared to white adults. Even mild elevations in blood pressure are associated with an increased risk for cardiovascular disease; therefore, early interventions for high blood pressure and hypertension are critical to assist in recommendations for lifestyle modification.
NYU Langone Health Named Coordinating Center for American Heart Association Health Equity Research Network to Prevent Hypertension in Black Communities
As part of a $20 million award from the America Heart Association, NYU Grossman School of Medicine has been named as the coordinating center for a new collaboration between eight universities to prevent hypertension and reduce racial inequities in cardiovascular disease outcomes in Black communities.
Obesity and Cardiovascular Factors Combine to Cause Cognitive Decline in Latinos
Obesity is a major public health issue among Latinos, and a risk factor for Alzheimer’s disease. But in a new study, researchers at UC San Diego report that cardiometabolic abnormalities, such as hypertension, are more strongly associated with cognitive decline than obesity alone.
Mobile apps can help those suffering from hypertension, improve communication between patients and providers
The use of physician-monitored mobile apps for tracking blood pressure can help curb the effects of chronic hypertension and improve communication between patients and providers, according to new research from Binghamton University, State University of New York.
Wayne State University and Henry Ford Health System announce new initiative in cardiometabolic health and disease
Wayne State University and Henry Ford Health System announced today the launch of a basic and translational research initiative in Cardiometabolic Health and Disease as a thematic focus for program growth.
Higher Selenium and Manganese Levels During Pregnancy May Protect Babies From Future High Blood Pressure
Children who were exposed to higher levels of trace minerals manganese and selenium during their mothers’ pregnancy had a lower risk of high blood pressure in childhood, according to a study led by researchers at the Johns Hopkins Bloomberg School of Public Health.
Obesity and hypertension: Researchers discover novel mechanisms
Hypertension is a widespread comorbidity of patients with obesity that greatly increases the risk of mortality and disability.
Unexpected discovery opens a new way to regulate blood pressure
A new discovery finds that zinc plays a critical and underappreciated role in blood pressure regulation, offering a potential new pathway for therapies to treat hypertension.
Vast under-treatment of diabetes seen in global study
Nearly half a billion people have diabetes, but only 1 in 10 of those in low- and middle-income countries are getting the kind of care that could make their lives healthier, longer and more productive, according to a new global study of data. Many don’t even know they have the condition.
Final results of SPRINT study confirm controlling blood pressure critically important in preventing heart disease and stroke
News release about the follow-up data from the landmark SPRINT study of the effect of high blood pressure on cardiovascular disease have confirmed that aggressive blood pressure management — lowering systolic blood pressure to less than 120 mm Hg — dramatically reduces the risk of heart disease, stroke, and death from these diseases, as well as death from all causes, compared to lowering systolic blood pressure to less than 140 mm Hg.
The enzyme that could help 700 million people worldwide
University of South Australia researchers have identified an enzyme that may help to curb chronic kidney disease, which affects approximately 700 million people worldwide.
Lifetime Monitoring Following Infant Cardiac Surgery May Reduce Future Hypertension Risk
In a medical records study covering thousands of children, a U.S.-Canadian team led by researchers at Johns Hopkins Medicine concludes that while surgery to correct congenital heart disease (CHD) within 10 years after birth may restore young hearts to healthy function, it also may be associated with an increased risk of hypertension — high blood pressure — within a few months or years after surgery.
Association between Hypertension and Gut Microbiome Imbalance during Pregnancy May Lead to New Preeclampsia Treatments
Article title: Gestational gut microbial remodeling is impaired in a rat model of preeclampsia superimposed on chronic hypertension Authors: Jeanne A. Ishimwe, Adesanya Akinleye, Ashley C. Johnson, Michael R. Garrett, Jennifer M. Sasser From the authors: “These results reveal an…
During pandemic, potentially avoidable hospitalizations for non-COVID conditions fell more among whites
New research suggests that the COVID-19 crisis has exacerbated existing racial health care disparities and that during the pandemic, African Americans may have had worse access than whites to outpatient care that could have helped prevent deterioration of their non–COVID-19 health conditions
Lower Enzyme Expression Prevents Elastin Insufficiency-induced Hypertension
New research published ahead of print in the journal Function suggests that blocking the expression of the NOX1 enzyme in mice may normalize blood pressure increases associated with elastin insufficiency. Elastin, a key protein that allows skin and other bodily…
New discovery explains antihypertensive properties of green and black tea
A new study from the University of California, Irvine shows that compounds in both green and black tea relax blood vessels by activating ion channel proteins in the blood vessel wall. The discovery helps explain the antihypertensive properties of tea and could lead to the design of new blood pressure-lowering medications.
Alcohol Plus Cadmium (via Smoking) Can Amplify Blood Pressure and Cardiovascular Risk
Heavy drinking combined with cadmium exposure — most commonly via smoking — escalates the risk of hypertension, according to a new study. Hypertension (high blood pressure) affects 26 percent of the global population and is the leading cause of cardiovascular disease and mortality. Alcohol consumption and cadmium exposure are known risk factors for hypertension. Exposure to cadmium, a metal that accumulates in body organs, occurs mainly through smoking, which often accompanies heavy drinking. Other cadmium sources include certain foods, air pollution, and wine and beer. Alcohol increases the absorption of cadmium in the body, and evidence suggests that the two substances contribute to hypertension via shared physiological pathways. The new study, in Alcoholism: Clinical & Experimental Research, is the first known epidemiological investigation of the combined effects of alcohol and cadmium on blood pressure.
Study Estimates Two-Thirds of COVID-19 Hospitalizations Due to Four Conditions
A new study estimates 64% of adult COVID-19 hospitalizations in the U.S. may have been prevented if there were less obesity, hypertension, diabetes, and heart failure. The model suggests notable differences by age and race/ethnicity in COVID-19 hospitalizations related to these conditions.
A New Beat Offers Free Online Seminar Examining Disparities in Cardiovascular Care During Heart Month
The Association of Black Cardiologists, Inc. (ABC) and the Cardiovascular Research Foundation (CRF) is offering a complimentary online seminar, “Tackling Disparities in CV Care: A Closer Look at Hypertension and Heart Failure” on Friday February 26, 2021. The program is part of a joint initiative called A New Beat which advocates for women and minorities rising as leaders in cardiology. It aims to foster careers of female and minority cardiologists, who can be poised to improve access to quality care for underserved populations.
Hypertensive Disorders of Pregnancy Associated with Risks of Structural Heart Changes a Decade After Delivery
The changes, which mainly affect the left ventricle of the heart, may predispose some women to ischemic heart disease and heart failure later in life.
Women Have a Lower Range of ‘Normal’ Blood Pressure Than Men
A new study from the Smidt Heart Institute at Cedars-Sinai shows that women have a lower “normal” blood pressure range compared to men. The findings were published today in the peer-reviewed journal Circulation.
Low-Income Middle-Aged African-American Women with Hypertension Are Likely to Suffer from Depression
Low-income middle-aged African-American women with high blood pressure very commonly suffer from depression and should be better screened for this serious mental health condition.
CRF Offers Free Online Seminar to Help People Jump-Start their Heart Health During Heart Month
The Cardiovascular Research Foundation (CRF) will hold a free online seminar, The Big Three: High Blood Pressure, High Cholesterol, and Diabetes, at 12:00 PM ET on February 22, 2021 hosted by Drs. Nisha Jhalani and Sonia Tolani, cardiologists from NewYork-Presbyterian/Columbia University Irving Medical Center. The seminar is part of a series of “Mini Med Schools” conducted by the CRF Women’s Heart Health Initiative (WHHI), which empowers women with everyday tools they can use to defy heart disease.
Sleep Apnea Does Not Raise Blood Pressure in Young Women
Article title: Sex differences in integrated neuro-cardiovascular control of blood pressure following acute intermittent hypercapnic-hypoxia Authors:Dain W. Jacob, Elizabeth P. Ott, Sarah E. Baker, Zachariah M. Scruggs, Clayton L. Ivie, Jennifer L. Harper, Camila M. Manrique-Acevedo, Jaqueline K. Limberg From…
Surgeon General expects COVID-19 vaccine to be available by year’s end
In a wide-ranging talk with UCLA Health physicians, Wednesday, Oct. 28, United States Surgeon General Jerome Adams, MD, MPH, addressed the politicization of the pandemic and the means of containing the spread of COVID-19. He also offered hope that a vaccine for the virus will be available by year’s end.
‘Heat-not-burn’ Alternative to E-cigarettes May Harm Heart
A new review suggests “heat-not-burn” tobacco devices may threaten cardiovascular health. The review is published ahead of print in the American Journal of Physiology-Heart and Circulatory Physiology.
Prevent Severe COVID Symptoms With Lifestyle Changes
Obesity is contributing to worse outcomes in people with COVID-19. Dr. Naomi Parrella, medical director of the Rush Center for Weight Loss and Bariatric Surgery, explains how managing your weight can lower your risk for severe COVID symptoms and help you prevent other chronic diseases.
Study shows high blood pressure awareness and control are declining in America
After nearly 15 years on an upward trend, awareness among Americans about their high blood pressure and rates of blood pressure control are now on the decline. many groups, including older adults and Black adults, are less likely than they were in earlier years to control their blood pressure.
American Heart Association Honors UVA Endocrinologist for Life’s Work on High Blood Pressure
Robert M. Carey, MD, has been named a Distinguished Scientist of the American Heart Association for his “extraordinary contributions” to cardiovascular research.
Mount Sinai Study Finds COVID Patients Were Most Commonly Readmitted to Hospital for Respiratory Complications
Study describes characteristics of patients with COVID-19 who returned to the ER or required readmission to the hospital within 14 days of being discharged
Sacubitril and Valsartan Combination Treatment May Reduce Hypertensive Kidney Disease
Article title: Differential effects of low-dose sacubitril and/or valsartan on renal disease in salt-sensitive hypertension Authors: Iuliia Polina, Mark Domondon, Rebecca Fox, Anastasia V. Sudarikova, Miguel Troncoso, Valeriia Y. Vasileva, Yuliia Kashyrina, Monika Beck Gooz, Ryan S. Schibalski, Kristine Y.…
In Firefighter Trainees, ‘Mediterranean Lifestyle’ Linked to Lower Health Risks
Young firefighter recruits who follow a ‘Mediterranean lifestyle’ are less likely to have hypertension (high blood pressure) and more likely to have good aerobic fitness, reports a study in the July Journal of Occupational and Environmental Medicine.
Cutting Down But Not Out: Very-Heavy Drinkers Needn’t Quit Completely for Cardiovascular Benefit
High-risk drinkers who substantially reduce their alcohol use can lower their risk of cardiovascular disease (CVD) despite not completely abstaining, according to study findings published in Alcoholism: Clinical and Experimental Research. CVD encompasses a range of conditions involving the heart or blood vessels, and is the leading cause of death in the US. It is also one of many negative health outcomes associated with heavy drinking and alcohol use disorder (AUD). Reductions in drinking can be defined using World Health Organization (WHO) ‘risk drinking levels’, which classify drinkers into ‘very high’, ‘high’, ‘moderate’ and ‘low’ risk categories based on their average daily alcohol consumption. Previous research has shown that a reduction of two or more levels (for example, from ‘very high’ to ‘moderate’) can lower the risk of multiple health issues, but did not assess the impact on CVD specifically. The latest study has examined associations between reductions in WHO risk drinking
Transgenic rice lowers blood pressure of hypertensive rats
Researchers reporting in ACS’ Journal of Agricultural and Food Chemistry have made transgenic rice that contains several anti-hypertensive peptides. When given to hypertensive rats, the rice lowered their blood pressure.
Clinical Trial to Investigate Whether Hypertension Drug Ameliorates COVID-19 Severity
UC San Diego scientists have launched a clinical trial to investigate whether a drug approved for treating high blood pressure might also reduce the severity of COVID-19 infections, lowering rates for intensive care unit admissions, the use of mechanical ventilators and all-cause mortality.
10-20-30 Interval Training Improves Blood Vessel Function in Men with High Blood Pressure
New research suggests that men with high blood pressure may have reduced blood vessel dilation in the legs and that a form of high-intensity interval exercise training improves blood vessel function in this population.
High-altitude adaptations connected with lower risk for chronic diseases
High-altitude adaptations in the Himalayas may lower risk for some chronic diseases, according to a research team including faculty from Binghamton University, State University of New York, the University of New Mexico, and the Fudan University School of Life Sciences.
How Do Commonly Used Blood Pressure Medications Affect Outcomes Among Patients with COVID-19?
A new international trial will evaluate whether the use of medications to treat high blood pressure affect outcomes among patients who are prescribed the medication and hospitalized with COVID-19. Investigators will examine whether ACEI or ARBs help to mitigate complications or lead to worse outcomes.
Chemicals used to replace BPA may lead to increased blood pressure
Common bisphenol A (BPA) substitutes can affect the developing fetus and cause hypertension in later life, suggests a rodent study accepted for presentation at ENDO 2020, the Endocrine Society’s annual meeting. The research will be published in a special supplemental section of the Journal of the Endocrine Society.
Diagnosing Hypertension in Children
• Study results call into question the utility of testing blood pressure load—the proportion of elevated blood pressure readings detected over 24 hours—for diagnosing hypertension in children.
Discovered: Why obesity causes high blood pressure — and potential ways to fix it
The researchers have already confirmed their discovery in human tissue samples and used it to reverse high blood pressure in lab mice.
Spinal Fluid Sodium May Play Role in Blood Pressure Management
Article title: Elevated cerebrospinal fluid sodium in hypertensive human subjects with a family history of Alzheimer’s disease Authors: Lucas A. C. Souza, Fatima Trebak, Veena Kumar, Ryousuke Satou, Patrick G. Kehoe, Wei Yang, Whitney Wharton, Yumei Feng Earley From the authors: “Our…