Clinical Trial Results Published in Nature Medicine Show Immunotherapy’s Potential in Resectable Esophageal and Gastroesophageal Junction Cancers and the Benefits of Monitoring Circulating Tumor DNA (ctDNA) to Measure Disease Response

The results of a study published today in Nature Medicine show exciting immune responses in patients with operable esophageal or gastroesophageal cancers given neoadjuvant immunotherapy. The study results also show the potential for monitoring circulating tumor DNA as a predictor for future intervention.

Hackensack Meridian Jersey Shore University Medical Center Welcomes Dr. Lee Peng as Chief of Gastroenterology

Hackensack Meridian Jersey Shore University Medical Center welcomed Lee F. Peng, M.D., PhD, as section chief of gastroenterology, department of medicine.

Baylor Scott & White Shares Insights At ACG Annual Scientific Meeting 2023

The 2023 American College of Gastroenterology (ACG) Annual Scientific Meeting & Postgraduate Course will convene in Vancouver, Canada, Oct. 20-25. The ACG is a recognized leader in educating GI professionals and the public about digestive disorders. The ACG’s mission is…

Case Western Reserve University and University Hospitals researchers awarded five-year, $11.2 million federal grant to study esophagus cancers

With a new five-year, $11.2 million grant from the National Cancer Institute (NCI), researchers at Case Western Reserve University and University Hospitals hope to learn what causes—and how to reduce and treat—esophagus cancers, an increasingly common and deadly disease.

Alcohol Use, Even at Low Levels, Increases Risk of Developing Disease

Even low levels of alcohol use can increase the likelihood of developing diseases like cancer and heart disease. A systematic review of studies of the relationship between alcohol use and risk of disease published in Alcohol: Clinical and Experimental Research found that disease risk increases as alcohol use increases and high levels of alcohol use have clear detrimental health effects. While lower-level alcohol use can be protective against certain diseases, it can have significant adverse health effects for many other diseases. The authors urge greater awareness that any level of alcohol use can increase a person’s risk of developing serious, even fatal, diseases.

Newly discovered RNA molecules hold promise for detecting and treating esophageal cancer

Irregularities in the body’s genetic coding to make proteins are linked to cancerous tumors. But most genetic material contains elements whose function isn’t clear. Could abnormalities in non-coding material also impact a person’s health, or even be linked to cancers as well? A new study by researchers at the Case Western Reserve University School of Medicine suggests that the non-coding genetic molecules also play a key role in health and disease, including tumor development.

New link found that connects cell signaling pathway to development of esophageal cancers, Barrett’s syndrome

A team of researchers at the Case Western Reserve University School of Medicine and Case Comprehensive Cancer Center believe they have identified a cell signaling pathway responsible for the development of esophageal adenocarcinomas, an aggressive form of esophageal cancer that has gradually become more common, even in younger people.

Delays in surgery for advanced esophageal cancer result in significantly worse survival than early surgery

Delays in surgery for esophageal cancer did not appear to have much impact on patients’ relative survival for early-stage cancer compared with patients who had surgery early, but they did reduce the relative survival rate by almost half for patients with more advanced disease.