Megan Greischar, assistant professor of ecology and evolutionary biology at Cornell University, studies parasites and the transmission of infection – particularly, malaria. Her recent research looked at malaria diagnostics and the impact on vaccine efficacy. Greischar says: “Eliminating vector-borne diseases…
Researchers propose a new way of understanding how diseases spread between animals and humans, by focusing on the effect that agriculture, ecological and sociopolitical factors have on disease emergence and transmission.
Joana Carneiro da Silva, PhD, Associate Director of Research & Associate Professor, Institute for Genome Sciences (IGS) at the University of Maryland School of Medicine. As malaria has now hit Maryland, Joana Carneiro da Silva, PhD, can speak to the…
The World Health Organisation (WHO) has updated its recommendation for malaria-preventing mosquito nets based on new research from the University of Adelaide.
There’s been an uptick in the U.S. recently in relatively obscure and rare diseases — malaria, leprosy, measles –– making a comeback, with many in the health community sounding the alarm bells. Philadelphia College of Osteopathic Medicine’s Brian DeHaven, PhD, an expert in virology and immunology,…
Jane Carlton, PhD, a biologist and leader in the field of comparative genomics, has joined the Johns Hopkins Bloomberg School of Public Health as director of the Johns Hopkins Malaria Research Institute. She assumed the role on August 1.
John Beier, an expert in vector biology and control at the Miller School of Medicine, answers questions about climate change’s impact on mosquitoes and on the locally transmitted cases of malaria in Florida.
The Florida Department of Health recently issued a mosquito-borne illness advisory following confirmed cases of malaria in Sarasota County, Florida. Malaria is a treatable, parasitic disease transmitted through mosquito bites. It affects the blood and causes flu-like symptoms, such as…
In a concerning development, the United States experienced its first cases of locally transmitted malaria in two decades, with five instances reported in Texas and Florida in June. This resurgence serves as a stark reminder of the looming threat posed…
The spread of malaria is dependent on Anopheles mosquitoes that spread the disease, and it persists in places, such as sub-Saharan Africa, where these types of mosquitoes exist and where there are enough people to keep the parasite thriving in humans. Human travel between…
WASHINGTON (July 6, 2023)— Five malaria cases have been reported in Florida and Texas in the last two months, the first locally transmitted malaria outbreak in the U.S. since 2003. The case — four in Florida and one recently announced on…
Using CRISPR technology, scientists have engineered a new way to genetically suppress populations of Anopheles gambiae, the mosquitoes that primarily spread malaria in Africa and contribute to economic poverty in affected regions.
This week, Carol Nwelue, MD, at Baylor Scott & White Health, answers common patient questions and reacts to the latest medical research. ▪ What is malaria, and how is it contracted? (SOT@ :14, TRT :12) ▪ What can you do to protect…
This week, the CDC issued an alert related to locally acquired cases of malaria in Florida and Texas. This is the first time in 20 years that malaria has been transmitted from within the US, according to the CDC. Ochsner…
WASHINGTON (June 28, 2023)— Five malaria cases have been reported in Florida and Texas in the last two months, the first locally transmitted malaria outbreak in the U.S. since 2003. The case — four in Florida and one recently announced…
The spread of malaria is dependent on Anopheles mosquitoes that spread the disease, and it persists in places, such as sub-Saharan Africa, where these types of mosquitoes exist and where there are enough people to keep the parasite thriving in…
Brian Grimberg, PhD, is just one of a team of experts at Case Western Reserve University who have been studying and working on a vaccine to combat Vivax for the last decade. Please let me know if you are interested…
This study is expected to generate critical evidence about the rise and expansion of drug-resistant parasites in Ethiopia. Results will help policymakers and advance malaria elimination efforts in Ethiopia and beyond.
How malaria parasites evolved to evade a major antimalarial drug has long been thought to involve only one key gene. Now, thanks to a combination of field and lab studies, an international research team has shown a second key gene is also involved in malaria’s resistance to the drug chloroquine.
The Johns Hopkins Malaria Research Institute at the Johns Hopkins Bloomberg School of Public Health will host its annual World Malaria Day Symposium Tuesday, April 25, from 8:30 a.m. to 5:45 p.m. EDT. The theme is the blood stage of malaria, which is the most devastating phase of the disease. The event will take place in person in Baltimore with thirteen panelists. A remote option is available to journalists.
After helping to develop and test new mRNA technologies for COVID-19 vaccines, University of Maryland School of Medicine (UMSOM) researchers and scientists are turning their attention to utilizing this innovative technology to ward off other infectious diseases like malaria and influenza.
In a bid to understand why mosquitoes may be more attracted to one human than another, Johns Hopkins Medicine researchers say they have mapped specialized receptors on the insects’ nerve cells that are able to fine-tune their ability to detect particularly “welcoming” odors in human skin.
Based on data that span the past 120 years, scientists at Georgetown University Medical Center have found that the mosquitoes responsible for transmitting malaria in Africa are spreading deeper into southern Africa and to higher elevations than previously recorded. The researchers estimate that Anopheles mosquito populations in sub-Saharan Africa have gained an average of 6.5 meters (21 feet) of elevation per year, and the southern limits of their ranges moved south of the equator by 4.7 kilometers (nearly 3 miles) per year.
If watching animals feast on human blood for 30-plus hours isn’t your idea of fun, don’t worry. The robot can do it.
monoclonal antibody treatment was found to be safe, well tolerated, and effective in protecting against malaria in a small group of healthy volunteers who were exposed to malaria in a challenge study, according to new research published in The Lancet Infectious Diseases by researchers at the University of Maryland School of Medicine (UMSOM).
Researchers have developed a new system for developing gene drives for areas ranging from human health to global food supplies. The new “hacking” system converts split gene drives into full drives, offering new flexibility for safely conducting gene drive experiments in a range of applications.
A three-dose regimen of a whole-parasite vaccine against malaria – called Plasmodium falciparum sporozoite (PfSPZ) vaccine – demonstrated safety and efficacy when tested in adults living in Burkina Faso, West Africa, which has endemic malaria.
Potentially life-saving insecticidal malaria nets, designed to be biologically effective for at least 3 years, may stop working well after just 12 months, suggests research of their use in one East African country and published online in the open access journal BMJ Global Health.
A new WWARN meta-analysis commissioned by the World Health Organization (WHO) which informed a change to its treatment guidelines* has been published in The Lancet.
In a paper recently published in Malaria Journal, global health researchers, Daniel Parker, PhD, assistant professor, and Guiyun Yan, PhD, professor, both from the UCI Program in Public Health, analyzed the movement ecology of humans in two places of heightened importance for Ethiopia’s malaria control and elimination strategies: Gambella and Benishangul-Gumuz (on the international border with Sudan and South Sudan).
One dose of an antibody drug safely protected healthy, non-pregnant adults from malaria infection during an intense six-month malaria season in Mali, Africa, a National Institutes of Health clinical trial has found.
Combining microbiology with engineering technologies, this novel 3D model uses a single microfluidic chip to study the complicated processes that take place in malaria-infected placenta as well as other placenta-related diseases and pathologies. The technology supports formation of microengineered placental barriers and mimics blood circulations, which provides alternative approaches for testing and screening.
Scientists at the University of Nottingham have made a major breakthrough in understanding how malaria parasites divide and transmit the disease, which could be a major step forwards in helping to prevent one of the biggest killer infections in the world.
Scientists at the University of Maryland School of Medicine’s (UMSOM) Institute for Genome Sciences (IGS) and the UMSOM Center for Vaccine Development and Global Health (CVD), and their collaborators report a new way to test vaccines that may be as rigorous and stringent as exposure to field strains of malaria.
WEHI researchers in Melbourne have made a crucial discovery about how asymptomatic malaria infections impact the body, informing potential strategies to control transmission and improve treatment outcomes.
In a newly published study, researchers at the University of Maryland School of Medicine have detected antibodies primarily made in response to infections in the mucous membranes — in such areas as the lungs, intestines, or vagina — in study participants with malaria.
This research, published in Nature Microbiology, showed that two genetic mutations to the parasite Plasmodium falciparum — the most common cause of malaria cases and deaths — allow it to escape detection from rapid tests.
The parasites that cause severe malaria are well-known for the sinister ways they infect humans, but new research may lead to drugs that could block one of their most reliable weapons: interference with the immune response.
The Johns Hopkins Malaria Research Institute at the Johns Hopkins Bloomberg School of Public Health will host its annual World Malaria Day Symposium this Friday, April 23, from 9 a.m. to 5:30 p.m. EDT.
Using venom from the Conus nux, a sea snail, a first-of-its-kind study suggests these conotoxins could potentially treat malaria. The study provides important leads toward the development of new and cost-effective anti-adhesion or blockade-therapy drugs aimed at counteracting the pathology of severe malaria. Similarly, mitigation of emerging diseases like COVID-19 also could benefit from conotoxins as potential inhibitors of protein-protein interactions as treatment. Venom peptides from cone snails has the potential to treat myriad diseases using blockage therapies.
Irvine, Calif., Nov. 3, 2020 — Employing a strategy known as “population modification,” which involves using a CRISPR-Cas9 gene drive system to introduce genes preventing parasite transmission into mosquito chromosomes, University of California researchers have made a major advance in the use of genetic technologies to control the transmission of malaria parasites.
Use of preventive antimalarial treatments reduces by half the number of malaria infections among schoolchildren, according to a new analysis published today in The Lancet Global Health.
Pregnant women from sub-Saharan Africa with malaria and human immunodeficiency virus (HIV) have a higher prevalence of anemia than pregnant women without infections according to Penn State College of Medicine researchers. The findings may have implications for reducing the risk of death in pregnant women and preventing low birth weights and neurocognitive impairment in their children as a result of anemia.
New Brunswick, N.J. (Aug. 3, 2020) – Rutgers University–New Brunswick Professor Robert E. Kopp is available to discuss a major study released today on the global consequences of climate change on death rates. The study by the Climate Impact Lab,…
Anopheles mosquitoes that have been genetically engineered with multiple anti-malaria molecules, acting at different stages of the malaria life cycle, are strongly resistant to the parasite that causes malaria and are unlikely to lose that resistance quickly, according to a study from scientists at Johns Hopkins Bloomberg School of Public Health.
The activity of the parasite that causes malaria is driven by the parasite’s own inherent clock, new research led by UT Southwestern scientists suggests.
UCLA is one of seven sites participating in a clinical trial investigating whether hydroxychloroquine, a commonly used anti-malarial and autoimmune drug, can prevent infection with COVID-19.
Malaria is a leading killer of children worldwide, and new drugs are needed. New research reports encouraging early clinical results with a new compound.
The National Institutes of Health has launched a $1 million Technology Accelerator Challenge (TAC) to spur the design and development of non-invasive, handheld, digital technologies to detect, diagnose and guide therapies for diseases with high global and public health impact. The Challenge is focused on sickle cell disease, malaria and anemia and is led by NIH’s National Institute of Biomedical Imaging and Bioengineering (NIBIB).
Scientists have identified a key molecule involved in the development of cerebral malaria, a deadly form of the tropical disease. The study identifies a potential drug target and way forward toward alleviating this condition for which few targeted treatments are available.