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UrduThe World Health Organization will release its World Malaria Report 2024 early next week. If you are preparing a story about this year’s report or writing broadly about malaria trends, the following researchers from the Johns Hopkins Malaria Research Institute…
Tag: Malaria
A New Approach to Predicting Malaria Drug Resistance
Researchers at UC San Diego analyzed the genomes of hundreds of malaria parasites to determine which genetic variants are most likely to confer drug resistance.
Study uncovers first evidence of resistance to standard malaria treatment in African children with severe malaria
An international team of researchers has uncovered evidence of partial resistance to artemisinin derivatives — the primary treatment for malaria — in young children with severe malaria.
Discovery of Critical Iron-Transport Protein in Malaria Parasites Could Lead to Faster-Acting Medications
New research from University of Utah Health has identified a promising target for new antimalarial drugs: a protein called DMT1, which allows single-celled malaria parasites to use iron. Preventing DMT1 activity causes parasites to die unusually quickly.
World Mosquito Day + dengue, malaria: Johns Hopkins experts available
This week, ahead of World Mosquito Day on Tuesday, August 20, top experts from the Johns Hopkins Bloomberg School of Public Health are available for interviews to discuss the ongoing threat of mosquito-borne diseases such as malaria and dengue. The…
Johns Hopkins Expert Briefing on Malaria – Current Research, Transmission Risks, and Reasons for Optimism
Ahead of World Malaria Day, the Johns Hopkins Bloomberg School of Public Health will host an expert briefing for the media about efforts to control and prevent malaria around the world. Malaria is a mosquito-borne disease that in 2022 took…
High Blood Pressure Linked to Increased Risk of Malaria in Mice
Rockville, Md. (April 4, 2024)—Hypertensive mice with abnormal red blood cells are at greater risk for developing malaria, according to a new study. Until now, the link between high blood pressure and malaria has not been extensively studied. Physiologists compared…
First DNA study of ancient Eastern Arabians reveals malaria adaptation – study
People living in ancient Eastern Arabia appear to have developed resistance to malaria following the appearance of agriculture in the region around five thousand years ago, a new study reveals.
Specific gut bacteria increase risk of severe malaria
Researchers have identified multiple species of bacteria that, when present in the gut, are linked to an increased risk of developing severe malaria in humans and mice. Their findings could lead to the development of new approaches targeting gut bacteria to prevent severe malaria and associated deaths.
Johns Hopkins Study Supports Potential for Injectable ‘Chemical Vaccine’ For Malaria Using Atovaquone
Johns Hopkins researchers looking to develop a long-acting, injectable malaria preventive using atovaquone have shown in a new study that resistance may not be the challenge scientists thought it was, particularly when using atovaquone as a malaria preventive.
Vaccine alone won’t eliminate malaria, but key addition to toolkit
Megan Greischar, assistant professor of ecology and evolutionary biology at Cornell University, studies parasites and the transmission of infection – particularly, malaria. Her recent research looked at malaria diagnostics and the impact on vaccine efficacy. Greischar says: “Eliminating vector-borne diseases…
Research analyzes relationship between agriculture, emergence of new diseases
Researchers propose a new way of understanding how diseases spread between animals and humans, by focusing on the effect that agriculture, ecological and sociopolitical factors have on disease emergence and transmission.
Malaria Genomic Research Critical as it Hits US
Joana Carneiro da Silva, PhD, Associate Director of Research & Associate Professor, Institute for Genome Sciences (IGS) at the University of Maryland School of Medicine. As malaria has now hit Maryland, Joana Carneiro da Silva, PhD, can speak to the…
Research informs WHO malaria net guideline update
The World Health Organisation (WHO) has updated its recommendation for malaria-preventing mosquito nets based on new research from the University of Adelaide.
Expert Available to Discuss Rise in Rare and Obscure Diseases
There’s been an uptick in the U.S. recently in relatively obscure and rare diseases — malaria, leprosy, measles –– making a comeback, with many in the health community sounding the alarm bells. Philadelphia College of Osteopathic Medicine’s Brian DeHaven, PhD, an expert in virology and immunology,…
Leading Researcher Jane Carlton Joins Bloomberg School of Public Health’s Johns Hopkins Malaria Research Institute as Director
Jane Carlton, PhD, a biologist and leader in the field of comparative genomics, has joined the Johns Hopkins Bloomberg School of Public Health as director of the Johns Hopkins Malaria Research Institute. She assumed the role on August 1.
Warming climate will expand mosquito’s realm
John Beier, an expert in vector biology and control at the Miller School of Medicine, answers questions about climate change’s impact on mosquitoes and on the locally transmitted cases of malaria in Florida.
MALARIA IN FLORIDA: FSU EXPERTS AVAILABLE TO COMMENT
The Florida Department of Health recently issued a mosquito-borne illness advisory following confirmed cases of malaria in Sarasota County, Florida. Malaria is a treatable, parasitic disease transmitted through mosquito bites. It affects the blood and causes flu-like symptoms, such as…
Experts on Malaria Outbreak in the U.S.
In a concerning development, the United States experienced its first cases of locally transmitted malaria in two decades, with five instances reported in Texas and Florida in June. This resurgence serves as a stark reminder of the looming threat posed…
UC Irvine expert can comment on spread of malaria in the U.S.
The spread of malaria is dependent on Anopheles mosquitoes that spread the disease, and it persists in places, such as sub-Saharan Africa, where these types of mosquitoes exist and where there are enough people to keep the parasite thriving in humans. Human travel between…
GW Experts Available to Comment on Malaria Outbreak in U.S.
WASHINGTON (July 6, 2023)— Five malaria cases have been reported in Florida and Texas in the last two months, the first locally transmitted malaria outbreak in the U.S. since 2003. The case — four in Florida and one recently announced on…
New Genetic Technology Developed to Halt Malaria-Spreading Mosquitoes
Using CRISPR technology, scientists have engineered a new way to genetically suppress populations of Anopheles gambiae, the mosquitoes that primarily spread malaria in Africa and contribute to economic poverty in affected regions.
Expert Addresses Latest Medical News Trends: Concerns About Malaria Cases in the U.S.
This week, Carol Nwelue, MD, at Baylor Scott & White Health, answers common patient questions and reacts to the latest medical research. ▪ What is malaria, and how is it contracted? (SOT@ :14, TRT :12) ▪ What can you do to protect…
CDC Health Alert on Malaria Cases – Ochsner Health Expert Available to Interview
This week, the CDC issued an alert related to locally acquired cases of malaria in Florida and Texas. This is the first time in 20 years that malaria has been transmitted from within the US, according to the CDC. Ochsner…
GW Experts Available to Comment on Malaria Outbreak in U.S.
WASHINGTON (June 28, 2023)— Five malaria cases have been reported in Florida and Texas in the last two months, the first locally transmitted malaria outbreak in the U.S. since 2003. The case — four in Florida and one recently announced…
Malaria cases detected in the U.S. Summer travel and warmer temperature
The spread of malaria is dependent on Anopheles mosquitoes that spread the disease, and it persists in places, such as sub-Saharan Africa, where these types of mosquitoes exist and where there are enough people to keep the parasite thriving in…
Malaria experts available to discuss Vivax cases found in Florida and Texas
Brian Grimberg, PhD, is just one of a team of experts at Case Western Reserve University who have been studying and working on a vaccine to combat Vivax for the last decade. Please let me know if you are interested…
UNC Researchers Receive NIH Grant to Study Drug-Resistant Malaria in Ethiopia
This study is expected to generate critical evidence about the rise and expansion of drug-resistant parasites in Ethiopia. Results will help policymakers and advance malaria elimination efforts in Ethiopia and beyond.
Second gene implicated in malaria parasite resistance evolution to chloroquine
How malaria parasites evolved to evade a major antimalarial drug has long been thought to involve only one key gene. Now, thanks to a combination of field and lab studies, an international research team has shown a second key gene is also involved in malaria’s resistance to the drug chloroquine.
Johns Hopkins Malaria Research Institute Hosting World Malaria Day Symposium on Tuesday, April 25
The Johns Hopkins Malaria Research Institute at the Johns Hopkins Bloomberg School of Public Health will host its annual World Malaria Day Symposium Tuesday, April 25, from 8:30 a.m. to 5:45 p.m. EDT. The theme is the blood stage of malaria, which is the most devastating phase of the disease. The event will take place in person in Baltimore with thirteen panelists. A remote option is available to journalists.
UM School of Medicine Researchers Chart Path Forward on Developing mRNA Vaccines for Infections Beyond COVID-19
After helping to develop and test new mRNA technologies for COVID-19 vaccines, University of Maryland School of Medicine (UMSOM) researchers and scientists are turning their attention to utilizing this innovative technology to ward off other infectious diseases like malaria and influenza.
Researchers Map Mosquito Cells That May Help the Insects Choose Tastiest Humans
In a bid to understand why mosquitoes may be more attracted to one human than another, Johns Hopkins Medicine researchers say they have mapped specialized receptors on the insects’ nerve cells that are able to fine-tune their ability to detect particularly “welcoming” odors in human skin.
Climate Change Portends Wider Malaria Risk as Mosquitos Spread South and to Higher Elevations in Africa
Based on data that span the past 120 years, scientists at Georgetown University Medical Center have found that the mosquitoes responsible for transmitting malaria in Africa are spreading deeper into southern Africa and to higher elevations than previously recorded. The researchers estimate that Anopheles mosquito populations in sub-Saharan Africa have gained an average of 6.5 meters (21 feet) of elevation per year, and the southern limits of their ranges moved south of the equator by 4.7 kilometers (nearly 3 miles) per year.
Bite this! Mosquito feeding chamber uses fake skin, real blood
If watching animals feast on human blood for 30-plus hours isn’t your idea of fun, don’t worry. The robot can do it.
Small Study Shows Promise for Antimalarial Monoclonal Antibody to Prevent Malaria
monoclonal antibody treatment was found to be safe, well tolerated, and effective in protecting against malaria in a small group of healthy volunteers who were exposed to malaria in a challenge study, according to new research published in The Lancet Infectious Diseases by researchers at the University of Maryland School of Medicine (UMSOM).
Researchers Create New System for Safer Gene-Drive Testing and Development
Researchers have developed a new system for developing gene drives for areas ranging from human health to global food supplies. The new “hacking” system converts split gene drives into full drives, offering new flexibility for safely conducting gene drive experiments in a range of applications.
A Three-Dose Malaria Vaccine Shows Safety, Efficacy in West African Adults
A three-dose regimen of a whole-parasite vaccine against malaria – called Plasmodium falciparum sporozoite (PfSPZ) vaccine – demonstrated safety and efficacy when tested in adults living in Burkina Faso, West Africa, which has endemic malaria.
Long-lasting insecticidal malaria nets’ biological effectiveness may be short-lived
Potentially life-saving insecticidal malaria nets, designed to be biologically effective for at least 3 years, may stop working well after just 12 months, suggests research of their use in one East African country and published online in the open access journal BMJ Global Health.
Meta-analysis informed the updated WHO guidelines for treatment of uncomplicated malaria in the first trimester of pregnancy
A new WWARN meta-analysis commissioned by the World Health Organization (WHO) which informed a change to its treatment guidelines* has been published in The Lancet.
Global health researchers use human movement patterns to determine risk of malaria spreading during certain times of day
In a paper recently published in Malaria Journal, global health researchers, Daniel Parker, PhD, assistant professor, and Guiyun Yan, PhD, professor, both from the UCI Program in Public Health, analyzed the movement ecology of humans in two places of heightened importance for Ethiopia’s malaria control and elimination strategies: Gambella and Benishangul-Gumuz (on the international border with Sudan and South Sudan).
Monoclonal Antibody Prevents Malaria Infection in African Adults
One dose of an antibody drug safely protected healthy, non-pregnant adults from malaria infection during an intense six-month malaria season in Mali, Africa, a National Institutes of Health clinical trial has found.
‘Placenta-on-a-chip’ Mimics Malaria-infected Nutrient Exchange between Mother-Fetus
Combining microbiology with engineering technologies, this novel 3D model uses a single microfluidic chip to study the complicated processes that take place in malaria-infected placenta as well as other placenta-related diseases and pathologies. The technology supports formation of microengineered placental barriers and mimics blood circulations, which provides alternative approaches for testing and screening.
A new study gives an important understanding of how molecular motor proteins are involved in malaria transmission
Scientists at the University of Nottingham have made a major breakthrough in understanding how malaria parasites divide and transmit the disease, which could be a major step forwards in helping to prevent one of the biggest killer infections in the world.
New Genomic Research Shows Why Testing Malaria Vaccines in the Clinic is as Rigorous as Natural Exposure in the Field
Scientists at the University of Maryland School of Medicine’s (UMSOM) Institute for Genome Sciences (IGS) and the UMSOM Center for Vaccine Development and Global Health (CVD), and their collaborators report a new way to test vaccines that may be as rigorous and stringent as exposure to field strains of malaria.
New discovery to improve malaria elimination strategies
WEHI researchers in Melbourne have made a crucial discovery about how asymptomatic malaria infections impact the body, informing potential strategies to control transmission and improve treatment outcomes.
Unexpected Antibody Type Found in People with Malaria Infections
In a newly published study, researchers at the University of Maryland School of Medicine have detected antibodies primarily made in response to infections in the mucous membranes — in such areas as the lungs, intestines, or vagina — in study participants with malaria.
Malaria Parasite Evolving to Evade Rapid Diagnostics in Africa
This research, published in Nature Microbiology, showed that two genetic mutations to the parasite Plasmodium falciparum — the most common cause of malaria cases and deaths — allow it to escape detection from rapid tests.
Blocking how the malaria parasite suppresses the immune response
The parasites that cause severe malaria are well-known for the sinister ways they infect humans, but new research may lead to drugs that could block one of their most reliable weapons: interference with the immune response.
THE JOHNS HOPKINS MALARIA RESEARCH INSTITUTE AT THE JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH HOSTING WORLD MALARIA DAY SYMPOSIUM FRIDAY, APRIL 23
The Johns Hopkins Malaria Research Institute at the Johns Hopkins Bloomberg School of Public Health will host its annual World Malaria Day Symposium this Friday, April 23, from 9 a.m. to 5:30 p.m. EDT.
Cone Snail Venom Shows Potential for Treating Severe Malaria
Using venom from the Conus nux, a sea snail, a first-of-its-kind study suggests these conotoxins could potentially treat malaria. The study provides important leads toward the development of new and cost-effective anti-adhesion or blockade-therapy drugs aimed at counteracting the pathology of severe malaria. Similarly, mitigation of emerging diseases like COVID-19 also could benefit from conotoxins as potential inhibitors of protein-protein interactions as treatment. Venom peptides from cone snails has the potential to treat myriad diseases using blockage therapies.