Research News Tip Sheet: Story Ideas from Johns Hopkins Medicine

During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every Tuesday throughout the duration of the outbreak.

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AACN Honors ‘5B’ Nurses Who Transformed Care for Patients With AIDS

Nurses Alison Moëd and Cliff Morrison will receive AACN Pioneering Spirit Awards for their efforts to transform treatment for patients with AIDS in the early 1980s. Together, they created the San Francisco Model, a patient-centered approach that improved the care for their patients and countless others around the world.

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New drug candidate reawakens sleeping HIV in hopes of functional cure

Scientists at Sanford Burnham Prebys Medical Discovery Institute have created a next-generation drug called Ciapavir (SBI-0953294) that is effective at reactivating dormant human immunodeficiency virus (HIV). The research, published in Cell Reports Medicine, aims to create a functional HIV cure by activating and then eliminating all pockets of dormant HIV—an approach called “shock and kill.”

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History of insightful HIV research inspires neutron scattering approach to studying COVID-19

What began as novel investigations into HIV, abruptly pivoted to the novel coronavirus as it began to spread across the globe. Now, ORNL researchers are using neutrons to learn more about the SARS-CoV-2 protease—a protein enzyme that enables the virus to replicate within the human body. Insights on the protein structure and its behaviors will be used to create more accurate models for simulations in aims of finding drug inhibitors to block the virus’s ability to reproduce.

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