Topics include the efficacy and safety of third-line treatment regimens in resource-limited settings, viral rebound rates after treatment interruption of modern ART, and whether a standardized frailty score can improve clinicians’ ability to estimate cardiovascular risk among older people with HIV.
Tag: HIV
Satya Dandekar honored with prestigious NIH MERIT award for HIV research
Satya Dandekar, professor of microbiology and chairperson of the Department of Medical Microbiology and Immunology at UC Davis, honored by Prestigious NIH MERIT award for her illustrious journey in HIV research.
UCLA receives nearly $14 million from NIH to investigate gene therapy to combat HIV
UCLA researchers and colleagues have received a $13.65 million grant from the National Institutes of Health to investigate and further develop an immunotherapy known as CAR T, which uses genetically modified stem cells to target and destroy HIV.
History of insightful HIV research inspires neutron scattering approach to studying COVID-19
What began as novel investigations into HIV, abruptly pivoted to the novel coronavirus as it began to spread across the globe. Now, ORNL researchers are using neutrons to learn more about the SARS-CoV-2 protease—a protein enzyme that enables the virus to replicate within the human body. Insights on the protein structure and its behaviors will be used to create more accurate models for simulations in aims of finding drug inhibitors to block the virus’s ability to reproduce.
Tip Sheet: HIV and COVID-19, antibody interactions, immune responses to colorectal cancer and how Fred Hutch is getting back to work
A monthly media tip sheet of recent Fred Hutch research findings and other news.
COVID-19 in People Living with HIV
Rutgers expert explains why COVID-19 pandemic poses additional difficulties, risks to people with HIV
Research News Tip Sheet: Story Ideas From Johns Hopkins
During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every Tuesday throughout the duration of the outbreak.
Potential new HIV treatment could mean once-a-year injection
The advance has the potential to eliminate complications that arise from missing doses of life-saving medicines, according to the study published today in Nature Materials, a leading peer-reviewed biomedical research journal.
Rutgers Expert Available to Speak About COVID-19 and Heightened Risk for Those Living with HIV
Preliminary data has shown that people living with HIV may be at heightened risk for severe complications from COVID-19 because they are simultaneously experiencing two epidemics that are synergistically interacting to create increased odds of death and disability. However, HIV…
Depressive Disorders Are ‘Under Recognized and Under Treated’ in People with HIV/AIDS
People living with HIV/AIDS are at increased risk of depressive disorders. But all too often, these conditions go unrecognized or untreated, suggests a literature review in the May/June issue of Harvard Review of Psychiatry. The journal is published in the Lippincott portfolio by Wolters Kluwer.
Shedding light on hidden HIV
Initiating antiretroviral therapy at a very early stage makes HIV reservoirs shrink by 100 times, researchers in Canada, the U.S. and Thailand find.
Scientists receive NIH grant to support study using THC as therapy for HIV patients suffering from inflammation
More than $3.7 million was awarded to Mahesh Mohan, DVM, MS, Ph.D., Professor at the Texas Biomedical Research Institute, and Chioma M. Okeoma, Ph.D., Associate Professor at Stony Brook University, to explore the link between cannabinoids (THC) and chronic intestinal inflammation in patients infected with the human immunodeficiency virus (HIV).
Tip Sheet: Tracking coronavirus, improving immunotherapies, cancer death rates decline, AAAS meeting and more
Summaries of recent Fred Hutch research studies, plus information on a press event at the upcoming AAAS annual meeting in Seattle.
HIV antibody therapy is associated with enhanced immune responses in infected individuals
In a study in Nature Medicine, researchers describe how injection of neutralizing antibodies are associated with enhanced T cell responses that specifically recognize HIV.
Researchers Reverse HIV Latency, Important Scientific Step Toward Cure
Overcoming HIV latency – activating HIV in CD4+ T cells that lay dormant – is a needed step toward a cure. Scientists at UNC-Chapel Hill, Emory University, and Qura Therapeutics – a partnership between UNC and ViiV Healthcare – showed it’s possible to drive HIV out of latency in two animal models.
BLOOD STEM CELL RESEARCH
A nanoparticle carrier system that could eliminate the need for bone marrow transplants, which are both expensive and difficult for patients to undergo. The University of Delaware’s Emily Day, an assistant professor of biomedical engineering, is developing a platform that could treat stem cells directly without the need to remove them from the body.
Intervention for patients hospitalized with HIV improved reengagement and outcomes of care
Providing multidisciplinary team consults for HIV patients while they are hospitalized to help address social and medical barriers reduces future infection rates and boosts participation in follow-up care, results from a study on how to reengage patients show.
New study shows pregnant women with HIV often not given recommended treatment
Pregnant women living with HIV don’t always receive antiretroviral medications recommended for use in pregnancy, according to a recent study published in Jama Network Open this week. Ann & Robert H. Lurie Children’s Hospital of Chicago’s researchers collaborated in the multi-site Surveillance Monitoring for ART Toxicities (SMARTT) study of the Pediatric HIV/AIDS Cohort Study (PHACS) network.
FY 2020 Spending Bill Funds Critical Initiatives While Neglecting Urgent Priorities
The spending bill passed today is a welcome step forward. Allocations in the bill will strengthen public health and research efforts during the year ahead and will provide critical support for important goals. At the same time, the legislation in its final form also brings inadequate responses to current and urgent challenges with the potential for long-term and costly consequences.
House Drug Pricing Bill Serves Patients, Public Health
H.R. 3, the Elijah E. Cummings Lower Drug Costs Now Act passed by the House of Representatives today introduces critically needed and significant steps to reduce costs and improve access to life-saving therapies for conditions including HIV and hepatitis C. Importantly, the legislation also brings essential resources to combat antibiotic resistance, find and develop new infection fighting drugs and bring them to market. The balanced approach of this legislation will serve patients and public health.
Johns Hopkins Experts Available in Observance of World AIDS Day
Nearly 40 million people around the world are living with HIV, and experts believe about 20% do not know their status. In the U.S., more than 1 million people in the U.S. are living with HIV.
Twitter chat with HIV/AIDS experts from the Johns Hopkins School of Nursing, Nov. 26, to prepare for World AIDS Day
The Johns Hopkins School of Nursing @JHUNursing is hosting a Twitter Chat in advance of World AIDS Day featuring its practitioners, researchers, and experts in HIV care, prevention, and science. Tuesday, November 26, 4:00 pm, EST Join and ask questions…
On the RISE: Joshua and Caleb Marceau Use NIGMS Grant to Jump-Start Their Research Careers
A college degree was far from the minds of Joshua and Caleb Marceau growing up on a small farm on the Flathead Indian Reservation in rural northwestern Montana.
Wound healing in mucous tissues could ward off AIDS
Some primates can carry SIV, a virus resembling HIV, lifelong and yet not develop AIDS. They are able to repair SIV damage to intestinal mucous tissues and avoid escape of gut bacteria and other events leading to immune system exhaustion. The findings offer clues for new HIV treatments
Mapping the pathway to gut health in HIV patients
A UC Davis study found that Lactobacillus plantarum bacteria rapidly repaired damaged gut lining (known as leaky gut) in monkeys infected with chronic simian immunodeficiency virus (SIV), an HIV-like virus. It linked chronically inflamed leaky gut to the loss of PPARα signaling and damage to mitochondria.
The Invisible US Hispanic/Latino HIV Crisis: Addressing Gaps in the National Response
American Journal of Public Health article sees heightened dangers for Hispanics/Latinos, and an urgent need for enhanced public-health response.
Injection drug use: not the same across Canada
A new study by researchers at the University of Montreal shows close to 172,000 Canadians injected drugs in 2016, up from 130,000 just five years earlier, but support varies.
How HIV Infection May Raise The Risk For Sudden Cardiac Death: New Study Sheds Light
The success of antiretroviral therapies has extended the lives of people living with HIV, long enough for other chronic health conditions to emerge, including a recently documented uptick in sudden death.
Sex workers’ preferences for HIV prevention center on convenience
Preventing HIV in sex workers is a powerful tool in lowering the worldwide burden of the disease, and a new study could help ensure that high-risk women take advantage of medical safeguards.
Scientists Make Surprising Discovery About Latent HIV Reservoir
HIV antiretroviral (ART) meds cannot completely eradicate the virus; it persists in immune cell “reservoirs.” Now scientists have discovered evidence that the initial use of ART alters the host environment to allow the formation or stabilization of most of the long-lived HIV reservoir.
New STD Data Represent Urgent Call for Action
The continued steep increase in incidence of sexually transmitted diseases reported in the 2018 data released by the U.S. Centers for Disease Control and Prevention Tuesday, is a cause for deep concern about dangerous gaps in our public health infrastructure.
HIV testing to expand with UChicago Medicine’s $4.5 million grant
More HIV testing will be available in the Chicago area, thanks to a five-year, $4.5 million federal public health grant recently awarded to the University of Chicago Medicine.
Living well, living longer with HIV-AIDS
A nurse scientist at Case Western Reserve University is further expanding her research on aging-related health challenges increasingly faced by people living longer with HIV-AIDS.
UC San Diego Researchers Isolate Switch that Kills Inactive HIV
University of California San Diego School of Medicine researchers have identified a switch controlling HIV reproduction in immune cells which can eliminate dormant HIV reservoirs.
Long-Acting Injectable Multi-Drug Implant Shows Promise for HIV Prevention and Treatment
A new study published today in Nature Communications shows a promising alternative for those who have to take a daily pill regimen.
Senate Subcommittees Takes Important Step Toward Ending HIV While Resources to Address Concurrent Epidemics, Housing Remain Critical, but Unaddressed
The Senate Labor, Health and Human Services and Related Programs Appropriations subcommittee’s allocations of funding for the Ending the HIV Epidemic initiative in its proposed budget for 2020 represent a significant step toward an ambitious, critical, and achievable goal; however, lack of new resources to confront increasing rates of hepatitis C and sexually transmitted diseases with insufficient support for addressing opioid-related infectious diseases, falls far short of the response to these concurrent epidemics that is needed.
Repeated Semen Exposure Promotes Host Resistance to Infection in Preclinical Model of HIV
Contrary to the long-held view that semen can only act as a way to transmit HIV-1 from men to women, scientists at The Wistar Institute and the University of Puerto Rico found that frequent and sustained semen exposure can change the characteristics of the circulating and vaginal tissue immune cells that are targets for infection, reducing the susceptibility to a future infection.
Randox launches whole pathogen Blood Borne Virus Controls at AACC
Whole pathogen Blood Borne Virus (BBV) controls have been brought to market by global diagnostics company Randox Laboratories.
AJPH Research- Marijuana use increases, nutrition labeling, barbershop HIV intervention
American Journal of Public Health August 2019 issue research highlights: High school students increased marijuana use, decreased tobacco and alcohol use 1991-2017 Newswise — From 1991 to 2017, the prevalence of marijuana-only use among U.S. high school students increased from 0.6% to…
Stephanie Shiau Joins the Rutgers School of Public Health
New Brunswick, NJ – The Rutgers School of Public Health is excited to announce that Stephanie Shiau, PhD, will be joining the department of biostatistics and epidemiology as an instructor in August. Shiau’s research focuses on the effects of human immunodeficiency virus (HIV)…