Clonal hematopoiesis of indeterminate potential (CHIP)is an independent risk factor for myocarditis after ICI therapy, a new Yale-led study finds. CHIP involves mutations in hematopoietic stem cells that can increase the risk of cardiovascular disease and worsen cancer outcomes. The condition is…
Tag: Cardiovascular Disease
New Report: Life Expectancy Years Shorter in the United States Compared to the United Kingdom
A new report from the Bloomberg American Health Initiative at the Johns Hopkins Bloomberg School of Public Health finds that life expectancy in the United States is, on average, 78.6 years versus 81.3 years in England and Wales, an overall 2.7-year difference.
Editorial Warns of Heart Disease Risks Associated with Yo-Yo Dieting
A new editorial – published in Nature – suggests that frequent fluctuations in diet, commonly known as “yo-yo dieting,” can significantly increase the risk of cardiovascular disease. The authors, from the University of Pennsylvania Schools of Nursing and Medicine, describe how cycling between high-fat and low-fat diets in mice led to a substantial acceleration of atherosclerosis, a condition characterized by the buildup of plaque in arteries.
New Study Finds Obesity Can Be Prevented in Very Young Children
A large study co-led by Kori Flower, MD, MS, MPH, division chief of General Pediatrics and Adolescent Medicine at the UNC School of Medicine demonstrates that combining text messaging with in-person clinic counseling reduces obesity in the first two years of life.
Think You’ve Outgrown Your High School Years? When It Comes To Drinking, A New Study Suggests Maybe Not
Adults aged 35 to 60 are drinking at unprecedented rates, with those who binge drank in high school reporting more past 30-day high-risk drinking in midlife. And this link may be especially strong for women, according to a study just published in Alcohol: Clinical and Experimental Research Health. These trends are particularly concerning as health conditions, and biological processes common with aging put adults in midlife at greater health risk from alcohol use.
Case Closed: Study Shows Vitamin D Supplementation Doesn’t Cut Cardiac Risk
Cardiovascular disease (CVD) is the primary cause of death among adults over age 65 years. Seniors are also likely to have low blood levels of Vitamin D, which has been linked to cardiovascular disease. Despite this, many observational trials have not demonstrated that Vitamin D supplementation reduces cardiovascular disease risk.
Native Hawaiian and Pacific Islander adults have third highest cardiovascular death rate in the U.S.
A study of nationwide mortality data found that Native Hawaiian Pacific Islander (NHPI) adults have substantially higher cardiovascular death rates than Asian adults and the third highest cardiovascular death rate in the United States behind Black and White adults.
Checking out the Boundaries: Milestone in Lipidomics Achieved
Results of the first phase of a Ceramide Ring Trial have just been published in the renowned journal Nature Communications, representing a significant landmark in the field of lipidomics.
Presence of Subclinical Atherosclerosis Is Marker of Mortality and Its Progression Increases Risk of Death
Mount Sinai study also shows imaging for early detection and monitoring can improve prediction and prevention of premature death
Chronic Kidney Disease Linked to Key Cardiovascular Risk Precursor
Rockville, Md. (September 17, 2024)—Overactivation of the sympathetic nervous system is a hallmark sign of chronic kidney disease (CKD) that increases the risk of cardiovascular disease. People with CKD often have impaired sympathetic baroreflex sensitivity—a measure of how well the…
Dolphin Serum Protects Blood Vessel Function in Older Mice
Article title: The bottlenose dolphin (Tursiops truncatus): A novel model for studying healthy arterial aging Authors: Yara Bernaldo de Quirós, Sophia A. Mahoney, Nicholas S. VanDongen, Nathan T. Greenberg, Ravinandan Venkatasubramanian, Pedro Saavedra, Gregory Bossart, Vienna E. Brunt, Zachary S. Clayton, Antonio…
Study shows long term-effects of immigration on Chinese Americans’ cardiovascular health
Chinese American immigrants face a higher risk of cardiovascular disease depending on length of residence and location in the U.S.
ADLM publishes new guidance on lipid testing to improve care for patients with cardiovascular disease
The Association for Diagnostics & Laboratory Medicine (ADLM, formerly AACC) has issued expert guidance on lipid tests, which measure blood levels of fats and cholesterol to help assess a patient’s risk of heart disease and stroke. By giving clinicians and laboratory medicine professionals much-needed clarity on how to best use these tests, the new guidelines will ensure that more patients with cardiovascular disease get the treatment they need.
Adults with chronic liver disease face more healthcare barriers than those with other diseases
UCLA researchers find that nearly 45% of adults with chronic liver disease encountered barriers to obtaining care compared with 34% of those with chronic obstructive pulmonary and/or cardiovascular disease, which are associated with a higher probability of recurrent acute care use…
New progress in wearable blood pressure monitoring enabled by flexible electronics and machine learning
Wearable cuffless blood pressure monitoring is expected to overcome the discomfort caused to patients by commonly used cuff sphygmomanometers in clinical settings. Flexible electronics and machine learning provide new impetus for the development of wearable cuffless blood pressure monitoring, bringing continuous and comfortable blood pressure monitoring to patients.
Swipe up! Health apps deliver real results en masse
They’re the dinky digital tools you can download in a few seconds, but despite their literal size, health and fitness apps pack a real punch when it comes to getting results, say researchers at the University of South Australia.
Cleveland Clinic Study Adds to Increasing Evidence that Sugar Substitute Erythritol Raises Cardiovascular Risk
New Cleveland Clinic research shows that consuming foods with erythritol, a popular artificial sweetener, increases risk of cardiovascular events such as heart attack and stroke. The findings, from a new intervention study in healthy volunteers, show erythritol made platelets (a type of blood cell) more active, which can raise the risk of blood clots.
Study Uncovers Connections Between Obesity and Heart Failure
A new small study led by Johns Hopkins Medicine researchers and published July 25th in the journal Nature Cardiovascular Research has revealed the impact of obesity on muscle structure in patients having a form of heart failure called heart failure with a preserved ejection fraction (HFpEF).
Uncontrolled Hypertension: The Old ‘Silent Killer’ is Alive and Well
High blood pressure affects about 45% of U.S. adults. In the 1970s, only about 50% of patients were aware of their hypertension. Today, 54% are aware of their high blood pressure, 40% are actively treated and 21% are actively controlled. As such, researchers alert health care providers that the old “silent killer” is alive and well.
Physical activity improves early with customized text messages in patients with heart problems
Personalized text messages effectively promoted increased physical activity for patients after significant heart events — such as a heart attack or surgery — but those effects later diminished.
BePRECISE consortium unveils guidelines to enhance reporting in precision medicine research
The inaugural reporting guidelines for precision medicine research, of which Wits University Professor Michèle Ramsay is co-author, have been published in Nature Medicine.
Harrisburg University Research Roundup: July 2024
Harrisburg, PA – Welcome to your July 2024 Harrisburg University of Science and Technology (HU) Research Roundup! Our talented students and faculty members are busy presenting at conferences, publishing boundary-pushing research, and building fruitful partnerships with schools, agencies, and organizations.…
UTSW study identifies RNA molecule that regulates cellular aging
A team led by UT Southwestern Medical Center researchers has discovered a new way that cells regulate senescence, an irreversible end to cell division.
NUTRITION 2024 Press Materials Available Now
Press materials are now available for NUTRITION 2024, the annual flagship meeting of the American Society for Nutrition (ASN). Top nutrition scientists and practitioners from around the world will gather to share the latest research findings on food and nutrition during the meeting in Chicago from June 29–July 2.
Cleveland Clinic Study Shows Weight Loss Surgery Cuts Risk of Heart Complications and Death in Patients with Obstructive Sleep Apnea and Obesity
A Cleveland Clinic study shows that bariatric surgery performed in patients with obesity and moderate to severe obstructive sleep apnea is associated with a significantly lower risk of death and major adverse cardiovascular events, compared with patients who did not have the surgery. This study was published in the Journal of the American College of Cardiology.
Ali Aminian, M.D., director of Cleveland Clinic’s Bariatric & Metabolic Institute and primary investigator of the MOSAIC study, said, “The research shows that weight loss achieved with bariatric surgery is significantly associated with a 42% lower risk of major adverse cardiovascular events and 37% lower risk of death in patients with obesity and moderate to severe obstructive sleep apnea.”
Climate Change-related Disturbances Linked to Worse Cardiovascular Health, Researchers Show
Cardiovascular disease (CVD) is the leading cause of death worldwide, accounting for approximately one in every three deaths, with more than 20 million deaths reported in 2021 according to a 2024 World Heart Federation report.
Valentin Fuster, MD, PhD, Received 2024 Distinguished Award From European Society for Clinical Investigation (ESCI)
President of Mount Sinai Fuster Heart Hospital given top honor for his scientific excellence and successful global education initiatives on cardiovascular disease
Fewer than 1 in 4 patients receive dietary counseling after a heart attack
Although diet is the leading contributor to premature death from heart disease in the United States, fewer than one-quarter of people who undergo major heart events receive dietary counseling in the aftermath, a study finds. The reason for such a low rate, researchers suggest, may be a lack of time for providing the counseling or expertise in this area by clinicians.
3D-printed grafts: a breakthrough in combating post-surgical thrombosis and aneurysm
A new study presents the development of 3D printed electrospun vascular grafts infused with tetramethylpyrazine (TMP), offering a potential solution to reduce thrombosis and restrain aneurysmal dilatation post-surgery. This innovation has potential implications for improving cardiovascular disease treatments.
Mount Sinai Experts to Present New Research on Long COVID, Lung Cancer, Asthma, Sleep Apnea, and More at ATS 2024 International Conference
Available for interview on breaking news, trending topics in respiratory medicine
Exercise does not accelerate artery plaque buildup more often seen in fitness enthusiasts
Exercising, even at extreme levels, does not accelerate the calcium buildup in arteries more often seen in marathoners and fitness enthusiasts, according to new research from UT Southwestern and the Cooper Institute. The study, which analyzed more than 8,700 participants…
Alarming Rise of Electronic Vaping Use in U.S. Adolescents
A study among 57,006 adolescents shows daily electronic vapor use has significantly increased by more than three-and-one-half times from 2015 to 2019. In 2015, daily use was significantly higher in boys (2.8%) than girls (1.1%). By 2021, it was higher in girls (5.6%) than boys (4.5%).
Researchers create human aortic aneurysm model to advance disease understanding, treatment testing
There are currently no medical treatments for thoracic aortic aneurysm. Using human cells in laboratory rats, researchers have developed a functional model of thoracic aortic aneurysm, creating opportunities for more effective understanding of disease development and treatments for the potentially fatal condition, a study suggests.
Intensive Blood Pressure Treatment May Help Some Middle-Aged Women
Investigators in the Smidt Heart Institute at Cedars-Sinai and colleagues report that women with Type 2 diabetes diagnosed with hypertension before age 50 may benefit from intensive blood pressure treatment.
Genetics predict type 2 diabetes risk and disparities in childhood cancer survivors
Learn how ancestry changes genetic risk variants’ impact on type 2 diabetes in childhood cancer survivors & alkylating agent exposure magnifies diabetes risk.
Earlier Menopause Plus High Cardiovascular Risk May Lead to Cognitive Problems Later
Earlier menopause combined with higher risk of cardiovascular disease is linked to an increased risk of thinking and memory problems later, according to a new study published in the April 3, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology. In this study, earlier menopause is defined as occurring before age 49.
Want to cut U.S. heart risks? Get more people into primary care, study suggests
When someone has a heart attack or a stroke, specialized care can give them the best chance of surviving.
FDA Approves Semaglutide for Heart Disease Prevention
Last week, the U.S. Food and Drug Administration approved the drug semaglutide, commonly known as Wegovy or Ozempic, to be used to reduce the risk of cardiovascular death, heart attack and stroke in adults with heart disease and obesity. Eric…
Novel risk score for cardiovascular complications after bone marrow transplant
While lifesaving, bone marrow transplants can affect various organs, including the cardiovascular system. Researchers led by Michigan Medicine have not only determined the contemporary prevalence of cardiovascular complications after bone marrow transplant — they developed a novel tool to predict a person’s risk for such problems following the procedure and help guide the pre-transplant process.The work formed the basis of a scientific statement published by the American Health Association geared towards the cardiovascular management of patients undergoing bone marrow transplant.
WEGOVY APPROVED FOR HEART RISK: U-Mich cardiology, obesity medicine experts available for interview
On March 8, the U.S. Food and Drug Administration approved a new indication for the use of semaglutide (brand Wegovy) to “reduce the risk of cardiovascular death, heart attack and stroke in adults with cardiovascular disease and either obesity or…
An aspirin a day? Poll of older adults suggests some who take it may be following outdated advice
One in four older adults take aspirin at least three times a week, mostly in hopes of preventing heart attacks and strokes, a new poll shows. But many people aged 50 to 80 who said they take aspirin may not need to because hey don’t have a history of cardiovascular disease.
Sedentary Behavior Increases Mortality Risk
According to new research from UC San Diego, sitting for long hours without breaks increases risk of death.
For Type II diabetes prevention, tap into AI
Better prevention of Type II diabetes could save both lives and money. The U.S. spends over $730 billion a year — nearly a third of all health care spending — on treating preventable diseases like diabetes.
Genes affect your blood pressure from early childhood
Certain genes associated with hypertension affect blood pressure from early in life, and they increase the risk of cardiovascular disease as you get older. However, you can do something about it.
Menopause and migraines: New findings point to power of prevention
Women who have both migraines and a long-term history of hot flashes and/or night sweats have a slightly higher risk of heart disease and stroke, and young women who have migraines have a higher risk of later persistent menopause symptoms, according to a new pair of papers.
Should heart patients consider taking weight loss medications?
Over the last year, prescriptions for medications that can accelerate weight loss in people with diabetes, or without it, have skyrocketed. But how can these weight loss medications affect the heart? A preventive cardiologist shares how this shifting landscape might affect cardiovascular care and how he advises his patients.
High biological age may increase the risk of dementia and stroke
People who have a higher biological age than their actual chronological age have an increased risk of stroke and dementia. The findings suggest that by slowing down the body’s aging processes, it may be possible to reduce or delay the onset of disease.
Women stroke survivors believe they will receive worse care in the emergency room
Women who have survived a stroke believe they are less likely to receive adequate emergency care – based on gender and race or ethnicity, a study shows. Researchers say future studies must focus on whether the beliefs these women hold about emergency care are leading to delays in stroke care.
RPI Alumnus Sheldon Weinbaum ’59 Named Recipient of National Medal of Science
A distinguished RPI alumnus and a member of the Class of 1959, Sheldon Weinbaum, Ph.D., was recognized with the National Medal of Science by U.S. President Joe Biden at a White House ceremony on October 24.
Mount Sinai Renames Top-Ranked Heart Hospital to Honor Valentin Fuster, MD, PhD, and His Legacy of Excellence
“Mount Sinai Fuster Heart Hospital” furthers vision of world-leading cardiac care and research that prevents heart disease worldwide