Heart Cell Protein Could Lead to New Treatments for Heart Failure and Recovery

A protein that helps regulate calcium signaling within heart cells could play a key role in preventing chronic heart failure, according to an international study led by University of Utah Health scientists. T The finding suggests that drugs and other therapeutic treatments targeting this protein could eventually help alleviate heart failure.

Atlantic Health System and NYU Langone Health Announce Partnership on Organ Transplantation

Two of the leading names in health care in the tri-state region, New Jersey–based Atlantic Health System and New York–based NYU Langone Health, are teaming up to give patients greater access to heart and liver transplants and the coordinated, high-quality care needed to stay healthy. The clinical affiliation will partner NYU Langone’s nationally recognized transplant program with the nationally ranked Atlantic Health System Heart Care program located at Morristown Medical Center’s Gagnon Cardiovascular Institute (Morristown, NJ) and the ground-breaking liver services at Overlook Medical Center (Summit, NJ).

Cardiologists at Henry Ford Are First in U.S. to Implant New Device to Treat Heart Failure, Improve Kidney Function

Cardiologists at Henry Ford Hospital are first in the U.S. and second in the world to implant a circulatory support device that is being investigated in a clinical trial for patients hospitalized with acute decompensated heart failure (ADHF) and worsening kidney function, a condition known as cardiorenal syndrome.

Fat Around the Heart Linked to Increased Risk of Heart Failure

EMBARGOED UNTIL MAY 24 2:00PM EST (New York, NY – May 24, 2021) – Having excess pericardial fat—fat around the heart—increases the risk of developing heart failure, especially in women, according to new Mount Sinai research. Women with high amounts…

Novel Rehab Program Improves Outcome for Older Heart-failure Patients, Study Finds

Heart failure (HF) – when the heart can’t pump enough blood and oxygen through the body – affects approximately 6.2 million adults in the United States and is the primary cause of hospitalization in the elderly. Unfortunately, older adults with heart failure often have poor outcomes resulting in reduced quality of life, high mortality and frequent rehospitalizations.

Study Estimates Two-Thirds of COVID-19 Hospitalizations Due to Four Conditions

A new study estimates 64% of adult COVID-19 hospitalizations in the U.S. may have been prevented if there were less obesity, hypertension, diabetes, and heart failure. The model suggests notable differences by age and race/ethnicity in COVID-19 hospitalizations related to these conditions.

A New Beat Offers Free Online Seminar Examining Disparities in Cardiovascular Care During Heart Month

The Association of Black Cardiologists, Inc. (ABC) and the Cardiovascular Research Foundation (CRF) is offering a complimentary online seminar, “Tackling Disparities in CV Care: A Closer Look at Hypertension and Heart Failure” on Friday February 26, 2021. The program is part of a joint initiative called A New Beat which advocates for women and minorities rising as leaders in cardiology. It aims to foster careers of female and minority cardiologists, who can be poised to improve access to quality care for underserved populations.

UHN launches study to explore how Apple Watch can help with early identification of worsening heart failure

Dr. Heather Ross launches a clinical study, with Apple to test if remote monitoring with Apple Watch can help with early identification of worsening heart failure. Data collected using an Apple Watch will be compared to data routinely collected from rigorous physical tests patients normally undergo.

Move quickly to relax

A team of Wayne State University School of Medicine researchers led by Charles Chung, Ph.D., assistant professor of physiology, recently received a $1,894,271 grant from the National Heart, Lung, and Blood Institute of the National Institutes of Health to address the critical need for new drug targets and diagnostic indexes for diastolic dysfunction using novel biomechanical tests that ultimately can be translated into clinical practice.

Enhanced Oral Uptake of Exosomes Opens Cell Therapy Alternative

Cell-derived exosomes are effective in treating disease when mixed with the dominant protein in breast milk and given orally, a new Smidt Heart Institute study of laboratory mice shows. The findings, published in the peer-reviewed Journal of Extracellular Vesicles, could help develop new oral medications for treating patients with muscular dystrophy and heart failure.

Common drug may protect hearts from damage caused by breast cancer chemotherapy

New research from UHN’s Peter Munk Cardiac Centre (PMCC) shows statins, commonly prescribed to lower cholesterol and reduce the risk of heart disease and stroke, may also protect the heart from damaging side-effects of early breast cancer treatment.

Research News Tip Sheet: Story Ideas from Johns Hopkins Medicine

During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every other Tuesday.

Research News Tip Sheet: Story Ideas From Johns Hopkins Medicine

During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every other Tuesday.

Ultrasounds Show Impact of COVID-19 on the Heart

International study may guide therapeutic strategies in patients with and without underlying heart conditions

Emerging Treatment Helps Reverse Heart Failure in Some Patients

In a new multicenter study, researchers led by University of Utah Health physicians report that an emerging heart failure treatment could potentially reverse structural damage to the heart, allowing it to heal itself over time. Overall, 19 (40%) patients who were treated with a combination of LVAD support with heart failure medications had sufficient improvement that the LVAD could be removed.

What Fuels the Beating Heart? Study Reveals Nutrients Used by Normal and Failing Hearts

A team led by Penn scientists produced a detailed picture of fuel and nutrient use by the human heart. The study was the first of its kind, involving the simultaneous sampling of blood from different parts of the circulatory system in dozens of human participants, in order to record the levels of related molecules going into and coming out of the beating heart.

Penn Researchers Receive Grant to Use AI to Improve Heart Transplant Outcomes

Researchers in the Perelman School of Medicine at the University of Pennsylvania were awarded a $3.2 million grant from the NIH to enhance research for improving heart transplant outcomes for patients. The four-year grant will fund a project exploring the use of AI-driven analysis to determine the likelihood of cardiac patients accepting or rejecting a new heart.

Exosome treatment improves recovery from heart attacks in a preclinical study

Research in pigs shows that using the exosomes naturally produced from a mix of heart muscle, endothelial and smooth muscle cells — all derived from human induced pluripotent stem cells — yields regenerative benefits equivalent to the injected human induced pluripotent stem cell-cardiac cells.

Study Shows Socioeconomic Status Linked to Heart Failure Mortality in United States

A variety of treatments exist to address heart disease, yet it continues to carry a poor prognosis. A new study from University Hospitals showed that a person’s address can help predict their chance of mortality from heart disease.

Gender Parity in Heart Failure Research: More Female Authors Could Mean More Female Participants

Representation of women leading heart failure research remains limited, according to new research led by Penn Medicine. The authors say the findings point to a need to support great gender diversity among researchers to drive diversity among clinical trial participants and even improve patient outcomes.

UNC Researchers Find Increase in Comorbidities among Hospitalized Patients with Heart Failure

A study recently published in the journal Circulation looks at temporal trends in the burden of comorbidities and associated risk of mortality among patients with heart failure (HF) with preserved ejection fraction (HFpEF), in which the left ventricle of the heart is not able to relax enough to fill properly with blood, and HF with reduced ejection fraction (HFrEF), in which the left ventricle is not able contract enough to pump out as much blood.

Precision medicine guides choice of better drug therapy in severe heart disease

Is personalized medicine cost-effective? Researchers have answered that question for one medical treatment, genotype-guided antiplatelet therapy for acute coronary syndrome patients with PCI. Their study uses pharmacogenomics and economic analysis of real-world clinical data.

Lung-Heart Super Sensor on a Chip Tinier Than a Ladybug

This chip’s detection bandwidth is enormous – from sweeping body motions to faint sounds of the heart as it beats, waves the heart sends through the body, respiration rate, and lung sounds.

Research News Tip Sheet: Story Ideas From Johns Hopkins

During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every Tuesday, throughout the duration of the outbreak.