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UrduWith one IV injection, a gene therapy targeting cBIN1 can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the amount of blood the heart can pump and dramatically improves survival.
Tag: Heart Failure
SLU Study: Black Patients with Heart Failure Less Likely to Receive Palliative Care
A study by researchers at Saint Louis University shows that only one in eight patients with heart failure in the United States receive palliative care consultations within five years of diagnosis. The study also highlighted significant racial and geographic disparities. Black people were 15% less likely to receive palliative care compared to their white counterparts.
SynCardia Granted Second Patent Covering Fully Implantable Artificial Heart
SynCardia Systems, LLC., a Picard Medical Inc. company, is pleased to announce that the United States Patent and Trademark Office (USPTO) has issued a second patent (US patent no. 12,121,711 B2) that will expand the coverage of SynCardia’s fully implantable artificial heart technology (SynCardia Emperor). The USPTO allowed the first patent (US patent no. 11,918,797) relating to its groundbreaking “Next Generation Total Artificial Heart” designs in March of this year.
UCLA researchers uncover novel role of protein GPNMB in heart repair
UCLA scientists have identified the protein GPNMB as a critical regulator in the heart’s healing process after a heart attack.
AI tool helps identify heart failure risk in diabetes patients
Researchers at UT Southwestern Medical Center have developed a machine learning model that can identify patients with diabetic cardiomyopathy, a heart condition characterized by abnormal changes in the heart’s structure and function that predisposes them to increased risk of heart failure. The findings, published in the European Journal of Heart Failure, offer a data-driven method to detect a high-risk diabetic cardiomyopathy phenotype, enabling early interventions that could help prevent heart failure in this vulnerable population.
Global Study Highlights the Life-Saving Impact of Guideline-Directed Medical Therapy (GDMT) in Heart Failure Patients
New UCLA-led research highlights the important role that the Guideline-Directed Medical Therapy can play in reducing mortality rates for individuals suffering from heart failure with reduced ejection fraction (HFrEF), a type of heart failure affecting an estimated 29 million people worldwide.
What is Heart Transplant Rejection?
A heart transplant is a lifesaving gift. But it means adjusting to a new way of life. Without anti-rejection measures, the body’s immune system will reject the transplanted heart.
Cedars-Sinai Again Earns 5-Star Rating From Federal Agency
Cedars-Sinai Medical Center again has earned a five-star hospital rating from the Centers for Medicare & Medicaid Services (CMS)—the highest distinction from the federal agency.
SGLT2 Inhibitor Empagliflozin Is Shown to Be Safe and Effective for Treating Patients Who Have Suffered a Heart Attack
The SGLT2 inhibitor empagliflozin confers kidney-protective benefits and can therefore be given safely and effectively to patients when they are hospitalized for acute myocardial infarction (MI), a Mount Sinai-led global team of researchers has shown.
5 Things Physicians Should Know About Pediatric Heart Failure
Pediatric heart failure is a progressive and life-threatening condition that can have a high mortality rate. Fortunately, thanks to new therapies now available, many children can recover—but this condition needs early recognition and treatment.
Borderzone Breakthrough: A new source of cardiac inflammation
In the Aug. 28, 2024 issue of Nature, researchers from University of California San Diego in the laboratory of Dr. Kevin King, associate professor of bioengineering and medicine, and a cardiologist at the Sulpizio Cardiovascular Center, report the discovery of a novel mechanism of cardiac inflammation that may expand therapeutic opportunities to prevent heart attacks from becoming heart failure.
Gut microbial pathway identified as target for improved heart disease treatment
Cleveland Clinic researchers have made a significant discovery about how the gut microbiome interacts with cells to cause cardiovascular disease.
Mejora del acceso a la detección de la insuficiencia cardíaca con saliva
En el calor abrasador del verano, cualquier persona que pase tiempo afuera podría beneficiarse de un tejido refrigerante. Pero ahora, los investigadores han innovado con un revestimiento de microescala a base de tiza que enfría el aire debajo del tejido tratado hasta 13 grados Celsius. Presentarán sus resultados en la ACS Fall 2024.
Improving access to heart-failure screening with saliva
Heart failure is especially fatal for people without access to medical facilities. A research team aims to bring heart failure screening from the lab to the home with a biosensor that uses a drop of saliva to screen for biomarkers of the disease. They will present their results at ACS Fall 2024.
Study Uncovers Connections Between Obesity and Heart Failure
A new small study led by Johns Hopkins Medicine researchers and published July 25th in the journal Nature Cardiovascular Research has revealed the impact of obesity on muscle structure in patients having a form of heart failure called heart failure with a preserved ejection fraction (HFpEF).
Roche showcases solutions for laboratories of the future at the Association for Diagnostics & Laboratory Medicine 2024 Clinical Lab Expo
● Roche will unveil the next generation of core lab and molecular systems, including a total solution for clinical mass spectrometry.
● Attendees can experience firsthand how fully integrated systems and data solutions can streamline lab operations, optimize resources and expedite care.
Second Heart Assist Announces an Impressive Successful Completion of a First-In-Human Case Study in Central America with its Whisper™ Device
Utah-based Second Heart Assist Inc., announced today the successful completion of the company’s first Central American case to evaluate the performance of its Whisper™ percutaneous mechanical circulatory device, designed to improve both cardiac function and renal perfusion in patients hospitalized with acute decompensated heart failure (ADHF). Second Heart Assist has already successfully performed FIH studies in Panama (South America) and other OUS countries for multiple indications.
American Heart Association Recognizes Loyola University Medical Center for Advanced Care for Stroke and Type 2 Diabetes
Loyola University Medical Center (LUMC) has earned the American Heart Association’s Get With The Guidelines® – Stroke Gold Plus quality achievement award for its commitment to ensuring stroke patients receive the most appropriate treatment according to nationally recognized, research-based guidelines, ultimately leading to more lives saved and reduced disability.
Advance in the Treatment of Acute Heart Failure Identified
A multicenter study led by Vanderbilt University Medical Center (VUMC) and Lipscomb University College of Pharmacy in Nashville has identified a potential new treatment for acute heart failure, a leading cause of hospitalization and death.
New study shows effect of socio-economic factors—housing, food, neighborhood—to predict diabetic patients’ risk of heart failure
A recent study by Case Western Reserve University used national data from U.S. military veterans with diabetes to validate and modify a widely accepted model used to predict the risk of heart failure in diabetic patients.
FDA Approves Semaglutide for Heart Disease Prevention
Last week, the U.S. Food and Drug Administration approved the drug semaglutide, commonly known as Wegovy or Ozempic, to be used to reduce the risk of cardiovascular death, heart attack and stroke in adults with heart disease and obesity. Eric…
People with Diabetes Who Live in Rural Areas More Likely to Develop Complications of the Disease, UM School of Medicine Study Finds
It has been well established that people who live in rural areas in the U.S. are more likely to have diabetes and experience barriers to managing their condition compared to those who live in the suburbs and cities.
THT 2024 Late-Breaking Clinical Science Announced
The complete list of late-breaking clinical science to be presented at THT 2024: Technology and Heart Failure Therapeutics is now available online. An international heart failure conference organized by the Cardiovascular Research Foundation® (CRF®), THT will take place March 4-6, 2024, at the Westin Boston Seaport in Boston, MA.
Long-term survivors of childhood cancer at higher risk of death following heart issues; threshold for treating risk factors should be lower
New research out of VCU Massey Comprehensive Cancer Center and VCU Health Pauley Heart Center indicates that survivors of childhood cancer are at a significantly higher risk of death following a major cardiovascular event — including heart failure, heart attack or stroke — than the general public.
Research Study on Novel Rehab Program for Heart Failure Patients, Led by Wake Forest University School of Medicine, Expands to Advocate Health Site in Chicago
Wake Forest University School of Medicine, the academic core of Advocate Health, is expanding another research study to Advocate Christ Medical Center, in Oak Lawn, Illinois, just outside Chicago.
The study, which is testing a novel rehabilitation program designed for older patients hospitalized with acute heart failure, is funded by a five-year, $30 million grant, awarded to Wake Forest University School of Medicine in 2022 by the National Institute on Aging, part of the National Institutes of Health.
Patients Diagnosed With New-Onset, Persistent AFib Are More Likely to Have These Risk Factors
Patients who present with persistent atrial fibrillation at diagnosis are more likely to have certain risk factors as compared with patients with occasional atrial fibrillation (AFib). The findings, led by investigators in the Smidt Heart Institute at Cedars-Sinai, published in Circulation: Arrhythmia and Electrophysiology.
Inaccurate pulse oximeter readings could limit transplants, heart pumps for Black patients with heart failure
University of Michigan researchers find that racially biased pulse oximeter readings may further limit opportunities for Black patients with heart failure — who are already less likely to get treatment — to receive potentially lifesaving therapies, such as heart pumps and transplants.
Heart attack significantly increases risk of other health conditions
Having a heart attack significantly increases the risk of developing other serious long-term health conditions, a major new study shows.
Risk Calculator Helps Personalize Care for Heart Failure Patients
A heart pump can save left heart failure patients’ lives, but the surgery to implant the pump often leads to right heart failure. Doctors now have a way to predict which patients are most at risk.
First classification of four stages of heart attack based on heart muscle damage is released
Canadian Cardiovascular Society consensus statement published in the Canadian Journal of Cardiology paves the way for refining treatment and providing individualized care
Cardiac Arrest: Hispanics, Latinos With Kidney Disease at High Risk
Hispanics and Latinos with chronic kidney disease are at significant risk for suffering from sudden cardiac arrest, according to a new study from the Smidt Heart Institute at Cedars-Sinai.
Baylor Scott & White Presents Research At The Heart Failure Society of America Annual Scientific Meeting 2023
The Heart Failure Society of America (HFSA) is a multidisciplinary organization working to improve and expand heart failure care through collaboration, education, research, innovation and advocacy. Its annual scientific meeting held Oct. 6-9, in Cleveland offers the best heart failure…
Beth Israel Lahey Health Launches Heart Transplant Program
Beth Israel Lahey Health has expanded its cardiovascular services to include heart transplantation based at Beth Israel Deaconess Medical Center.
UAH Nursing researcher to study cardiometabolic disease among Black women in the Deep South
A researcher at The University of Alabama in Huntsville (UAH) has been awarded a $179,000 subcontract to explore community-based strategies for reducing high-burden chronic disease like obesity, diabetes, heart disease and cancer as part of an overall award totaling $4.2 million.
Mechanism of adipose-derived mesenchymal stem cell exosomes in the treatment of heart failure
BACKGROUNDHeart failure (HF) is a global health problem characterized by impaired heart function. Cardiac remodeling and cell death contribute to the development of HF. Although treatments such as digoxin and angiotensin receptor blocker dr
Mount Sinai Announces Partnership With the Brazilian Clinical Research Institute to Advance Cardiovascular Disease Research and Medical Education
Agreement aims to improve patient care and outcomes on a global scale
Ohio State first in world to participate in trial of device designed to alleviate heart failure symptoms
The Ohio State University Wexner Medical Center on Wednesday randomized the first patient in the world in a clinical trial evaluating the effectiveness of a device designed to alleviate heart failure symptoms.
Multicenter Trial Finds Using Circulatory Death Donors is Safe and Effective for Heart Transplantation
A study published in New England Journal of Medicine confirms that circulatory death donor hearts that are reanimated and perfused with blood outside of the body are as safe and effective to transplant as brain death donor hearts preserved using traditional cold storage. These findings suggest that using hearts donated after circulatory death (DCD) may have the potential to widen the donor pool helping more patients in need of life-saving heart transplants.
Devastating heart condition can be reversed, study shows for the first time
Three men who had heart failure caused by the build-up of sticky, toxic proteins are now free of symptoms after their condition spontaneously reversed in an unprecedented case described by a team at UCL and the Royal Free Hospital.
New Heart Transplant Method May Grow Donor Pool 30%
A study led by Duke Health physicians, appearing online June 8 in the New England Journal of Medicine, found that DCD hearts were equivalent to hearts procured through the current standard of care.
High copayments for novel therapies may reduce patients’ medication adherence
UCLA-led study shows that patients with diabetes and heart failure who have high medication copayments for novel therapies have a significantly lower chance of consistently adhering to these medications.
Heart failure deadly and under-treated in most countries, says a study in 40 countries
Global Variations in Heart Failure Etiology, Management, and OutcomesPublished in JAMA May 16, 2023https://jamanetwork.com/journals/jama/fullarticle/2804824?resultClick=1doi:10.1001/jama.2023.5942 Key Points Question How do heart failure etiology, treatment, and outcomes differ between groups of countries at different levels of economic development? Findings Ischemic heart disease and hypertension…
TVT 2023 Late-Breaking Science Announced
The Cardiovascular Research Foundation (CRF) announced that TVT: The Structural Heart Summit will feature 15 Late-Breaking Clinical Science studies. An annual meeting featuring cutting-edge research and techniques for structural heart interventions, TVT will take place June 7-10, 2023, at the Phoenix Convention Center – West in Phoenix, Arizona.
Adolescents, young adults with advanced heart disease show desire to take active role in medical care decisions
Parents, as well as pediatric healthcare clinicians, may want to protect young people from difficult new about their advanced heart disease but many adolescents and young adults prefer being engaged with medical decision-making.
In first in-utero brain surgery, doctors eliminated symptoms of dangerous condition
For the first time, researchers performed a successful in-utero surgery to repair a potentially deadly developmental condition by treating an aggressive vascular malformation, called vein of Galen malformation, in a fetus’s brain before birth.
Aggressive Blood Pressure Control May Prevent Common Heart Condition
Left ventricular conduction disease occurs when there is an electrical blockage of the heart’s normal electrical conduction system. Treatment to lessen its effects involves implanting a permanent pacemaker, but there have been no proven preventive strategies for this condition. In a study publishing May 3, 2023 in JAMA Cardiology, first author Emilie Frimodt-Møller, MD, and senior author Gregory Marcus, MD, MAS, found that intensive BP control is associated with lower risk of left ventricular conduction disease, indicating left ventricular conduction disease may be preventable.
TVT 2023 Program Guide Available
The program guide for TVT 2023: The Structural Heart Summit is available online. An annual meeting from the Cardiovascular Research Foundation (CRF), TVT features cutting-edge research and techniques for structural heart interventions and will take place June 7-10, 2023, at the Phoenix Convention Center – West in Phoenix, Arizona.
Cause of heart damage from cancer drugs identified
Safer cancer drugs are now one step closer after a new study led by UCL (University College London) researchers found the likely reason that some treatments damage the heart.
Seven Hackensack Meridian Medical Centers Recognized for Excellence with ACC Heart Failure Accreditation
Facilities that achieve accreditation meet or exceed an array of stringent criteria and have organized a team of doctors, nurses, clinicians and other administrative staff that earnestly support the efforts leading to better patient education, improved patient outcomes, and more effective and efficient disease control.
U-CARS 2023: Healing Diseased Hearts, from Bench to Bedside
Now in its 11th year, participants in Utah Cardiac Recovery Symposium (U-CARS) will exchange ideas and evaluate paradigms on a now-thriving field of science and medicine that was once thought to be impossible: making diseased hearts healthy again.