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UrduA researcher at The University of Alabama in Huntsville (UAH) has been awarded a $179,000 subcontract to explore community-based strategies for reducing high-burden chronic disease like obesity, diabetes, heart disease and cancer as part of an overall award totaling $4.2 million.
Tag: Heart Failure
Mechanism of adipose-derived mesenchymal stem cell exosomes in the treatment of heart failure
BACKGROUNDHeart failure (HF) is a global health problem characterized by impaired heart function. Cardiac remodeling and cell death contribute to the development of HF. Although treatments such as digoxin and angiotensin receptor blocker dr
Mount Sinai Announces Partnership With the Brazilian Clinical Research Institute to Advance Cardiovascular Disease Research and Medical Education
Agreement aims to improve patient care and outcomes on a global scale
Ohio State first in world to participate in trial of device designed to alleviate heart failure symptoms
The Ohio State University Wexner Medical Center on Wednesday randomized the first patient in the world in a clinical trial evaluating the effectiveness of a device designed to alleviate heart failure symptoms.
Multicenter Trial Finds Using Circulatory Death Donors is Safe and Effective for Heart Transplantation
A study published in New England Journal of Medicine confirms that circulatory death donor hearts that are reanimated and perfused with blood outside of the body are as safe and effective to transplant as brain death donor hearts preserved using traditional cold storage. These findings suggest that using hearts donated after circulatory death (DCD) may have the potential to widen the donor pool helping more patients in need of life-saving heart transplants.
Devastating heart condition can be reversed, study shows for the first time
Three men who had heart failure caused by the build-up of sticky, toxic proteins are now free of symptoms after their condition spontaneously reversed in an unprecedented case described by a team at UCL and the Royal Free Hospital.
New Heart Transplant Method May Grow Donor Pool 30%
A study led by Duke Health physicians, appearing online June 8 in the New England Journal of Medicine, found that DCD hearts were equivalent to hearts procured through the current standard of care.
High copayments for novel therapies may reduce patients’ medication adherence
UCLA-led study shows that patients with diabetes and heart failure who have high medication copayments for novel therapies have a significantly lower chance of consistently adhering to these medications.
Heart failure deadly and under-treated in most countries, says a study in 40 countries
Global Variations in Heart Failure Etiology, Management, and OutcomesPublished in JAMA May 16, 2023https://jamanetwork.com/journals/jama/fullarticle/2804824?resultClick=1doi:10.1001/jama.2023.5942 Key Points Question How do heart failure etiology, treatment, and outcomes differ between groups of countries at different levels of economic development? Findings Ischemic heart disease and hypertension…
TVT 2023 Late-Breaking Science Announced
The Cardiovascular Research Foundation (CRF) announced that TVT: The Structural Heart Summit will feature 15 Late-Breaking Clinical Science studies. An annual meeting featuring cutting-edge research and techniques for structural heart interventions, TVT will take place June 7-10, 2023, at the Phoenix Convention Center – West in Phoenix, Arizona.
Adolescents, young adults with advanced heart disease show desire to take active role in medical care decisions
Parents, as well as pediatric healthcare clinicians, may want to protect young people from difficult new about their advanced heart disease but many adolescents and young adults prefer being engaged with medical decision-making.
In first in-utero brain surgery, doctors eliminated symptoms of dangerous condition
For the first time, researchers performed a successful in-utero surgery to repair a potentially deadly developmental condition by treating an aggressive vascular malformation, called vein of Galen malformation, in a fetus’s brain before birth.
Aggressive Blood Pressure Control May Prevent Common Heart Condition
Left ventricular conduction disease occurs when there is an electrical blockage of the heart’s normal electrical conduction system. Treatment to lessen its effects involves implanting a permanent pacemaker, but there have been no proven preventive strategies for this condition. In a study publishing May 3, 2023 in JAMA Cardiology, first author Emilie Frimodt-Møller, MD, and senior author Gregory Marcus, MD, MAS, found that intensive BP control is associated with lower risk of left ventricular conduction disease, indicating left ventricular conduction disease may be preventable.
TVT 2023 Program Guide Available
The program guide for TVT 2023: The Structural Heart Summit is available online. An annual meeting from the Cardiovascular Research Foundation (CRF), TVT features cutting-edge research and techniques for structural heart interventions and will take place June 7-10, 2023, at the Phoenix Convention Center – West in Phoenix, Arizona.
Cause of heart damage from cancer drugs identified
Safer cancer drugs are now one step closer after a new study led by UCL (University College London) researchers found the likely reason that some treatments damage the heart.
Seven Hackensack Meridian Medical Centers Recognized for Excellence with ACC Heart Failure Accreditation
Facilities that achieve accreditation meet or exceed an array of stringent criteria and have organized a team of doctors, nurses, clinicians and other administrative staff that earnestly support the efforts leading to better patient education, improved patient outcomes, and more effective and efficient disease control.
U-CARS 2023: Healing Diseased Hearts, from Bench to Bedside
Now in its 11th year, participants in Utah Cardiac Recovery Symposium (U-CARS) will exchange ideas and evaluate paradigms on a now-thriving field of science and medicine that was once thought to be impossible: making diseased hearts healthy again.
University of Utah and TikkunLev Therapeutics announce new partnership to accelerate heart-failure gene therapy
The new partnership aims to accelerate an innovative heart-failure gene therapy. The agreement is an exclusive world-wide license and includes a sponsored research program to support future FDA filings.
Transcatheter Mitral Valve Repair in Heart Failure Patients Significantly Reduces Hospitalizations and Improves Survival
Breakthrough findings from study led by Mount Sinai researcher could improve outcomes for high-risk patients
THT 2023 Late-Breaking Clinical Science Announced
The full list of late-breaking clinical science to be presented at THT 2023: Technology and Heart Failure Therapeutics is now available online. An international heart failure conference organized by the Cardiovascular Research Foundation (CRF), THT will take place March 20-22, 2023, at the Westin Boston Seaport in Boston, MA.
Anti-ageing gene shown to rewind heart age by 10 years
An anti-ageing gene discovered in a population of centenarians has been shown to rewind the heart’s biological age by 10 years. The breakthrough, published in Cardiovascular Research and led by scientists at the University of Bristol and the MultiMedica Group in Italy, offers a potential target for patients with heart failure.
Smidt Heart Institute Experts to Lead Training Sessions at Society of Thoracic Surgeons Conference
Cardiothoracic surgeons and investigators from the Smidt Heart Institute at Cedars-Sinai bring their leading-edge expertise in heart and lung surgery to the 59th Annual Meeting of The Society of Thoracic Surgeons (STS), Jan. 21-23, 2023, in San Diego.
Lonely heart-failure patients face worse outcomes than sociable peers
Older heart failure patients who feel that they have lost their social role amongst friends and family are more likely to suffer poor clinical outcomes.
Mouse study suggests new therapeutic strategy to reduce cardiovascular disease in cancer survivors
Researchers at Memorial Sloan Kettering Cancer Center (MSKCC) in New York have discovered that common cancer treatments, such as radiotherapy or anthracycline drugs, cause long-term damage to heart tissue by activating a key inflammatory signaling pathway. The study, published December 19 in the Journal of Experimental Medicine (JEM), suggests that inhibiting this pathway could reduce the chances of cancer survivors suffering heart disease later in life.
Study finds that patients with heart failure with improved ejection fraction benefit from the SGLT2 inhibitor dapagliflozin
With modern therapies for heart failure (HF) with reduced ejection fraction (HFrEF), some patients can improve their cardiac function during treatment.
Albert Einstein College of Medicine and Montefiore Health System Receive $5.2 Million NIH Grant to Study Heart Failure in Hispanic Populations
Cardiology researchers at Albert Einstein College of Medicine and Montefiore Health System have received a five-year, $5.2 million grant from the National Institutes of Health (NIH) to explore the underlying causes of heart failure among Hispanics/Latinos, who are at heightened risk for heart disease. Investigators will take a novel approach to assess risk: by simultaneously evaluating heart function and the relationship between the heart and the aorta, the large artery that conveys oxygen-rich blood from the heart’s left ventricle to the rest of the body.
They May Need New Hearts but They’re Still Very Happy to be Alive & Celebrating the Holidays Together
While it may look like any other holiday party with food, music and decorations, it’s the party-goers that make this celebration quite unique – many of them have advanced heart failure and are in need of a heart transplant. Still,…
Novel Wearable Belt with Sensors Accurately Monitors Heart Failure 24/7
There is a critical need for non-invasive solutions to monitor heart failure progression around the clock. This novel wearable device is based on sensors embedded in a lightweight belt that monitors thoracic impedance, electrocardiogram (ECG), heart rate and motion activity detection. The device was tested in different conditions including sitting, standing, lying down and walking. Findings showed that all of sensors kept track of the changes for all of the different conditions.
Study shows heart failure treatment with dapagliflozin consistently benefited both men and women
When it comes to heart failure (HF), sex differences are known to impact everything from risk factors to clinical presentation to response to treatment, making sex a key factor to consider in studies of emerging pharmacotherapies.
Comparative Study of Two Heart Failure Drugs Finds No Difference in Outcomes
In a head-to-head comparison of two so-called ‘water pills’ that keep fluid from building up in patients with heart failure, the therapies proved nearly identical in reducing deaths, according to a large study led by Duke Health researchers.
Deepak L. Bhatt, MD, MPH, Named Director of Mount Sinai Heart
Will also serve as the first-ever Dr. Valentin Fuster Professor of Cardiovascular Medicine
Immune marker suPAR high in patients with heart failure, predicts risk and death
Levels of the immune protein suPAR are high in patients with heart failure and predict both heart failure and death, a new study suggests. Beyond that, when suPAR is combined with BNP, a downstream indicator of heart failure, the ability to predict such risks gets even stronger.
Researchers Receive $30 Million Award to Study Novel Rehab Program for Heart Failure Patients
Wake Forest University School of Medicine has received a five-year, $30 million grant to test a novel rehabilitation program designed for older patients hospitalized for acute heart failure.
UChicago Medicine’s heart transplant program makes history again, with best survival rates and wait times ever recorded
The University of Chicago Medicine’s heart transplant program is making history once again. The program’s transplant survival rates and transplant wait times are not only the best in the country, but they’re the best in the history of heart transplantation, according to an analysis of Scientific Registry of Transplant Recipients (SRTR) data.
15 Years of Heart
Pioneering heart care is a tradition at Cedars-Sinai. It’s a tradition that took root in 1924, when Cedars-Sinai became home to the first electrocardiogram machine in Los Angeles.
Cleveland Clinic-Led Trial Finds That Increasing Salt Intake Does Not Affect Patients Hospitalized with Congestive Heart Failure During Treatment
Cleveland: Findings from a Cleveland Clinic-led trial show that increasing the salt intake by mouth for patients who are hospitalized with heart failure undergoing aggressive diuretic therapy did not affect how much fluid they retain or their kidney function, indicating that salt intake for heart failure patients may not be as harmful as previously thought. Conversely, these new findings may challenge the common practice of salt restriction during hospital admission since that might not be as helpful.
New Data Shows 85% Reduction in One-Year Mortality for Medicare Heart Failure Patients With BVA-Guided Care
New data validate the benefits of the BVA-100 blood volume measurement test for Medicare heart failure patients. Data were presented at the Heart Failure Society of America (HFSA) Annual Scientific Meeting (ASM) 2022 – which brought together the world’s leading experts in heart failure.
Puzzle Medical Devices Inc. Wins TCT 2022 Shark Tank Innovation Competition
The Cardiovascular Research Foundation (CRF) is pleased to announce that Puzzle Medical Devices Inc. has won the TCT 2022 Shark Tank Innovation Competition for its novel circulatory support device that is implanted percutaneously in the abdominal aorta. The competition took place during Transcatheter Cardiovascular Therapeutics (TCT), the world’s premier educational meeting specializing in interventional cardiovascular medicine, September 16-19 in Boston. The winner was also presented with the Jon DeHaan Foundation Award for Innovation in Cardiology.
Boosting duration, intensity & frequency of physical activity may lower heart failure risk
A six-year analysis of more than 94,000 adults in the U.K. Biobank with no history of heart failure at enrollment has found that engaging in moderate or vigorous physical activity may lower the risk of developing heart failure, according to new research published today in the American Heart Association’s flagship journal Circulation.
New Risk Score Predicts Mortality for Atrial Fibrillation Patients Undergoing Transcatheter Aortic Valve Replacement
Mount Sinai researchers develop new risk stratification tool to optimize patient care and outcomes after TAVR
CRF and Fogarty Innovation Announce Agenda For TCT MedTech Innovation Forum
The Cardiovascular Research Foundation (CRF) and Fogarty Innovation announced today that the program is now available for the TCT MedTech Innovation Forum. The summit will be held on the first day of TCT, the annual scientific symposium of CRF, on Friday, September 16. TCT will take place September 16-19, 2022, in Boston, Massachusetts, at the Boston Convention and Exhibition Center.
COVID mRNA vaccines are safe in patients with heart failure
COVID mRNA vaccines are associated with a decreased risk of death in patients with heart failure, according to research presented at ESC Congress 2022.
Hackensack Meridian Pascack Valley Medical Group expands cardiology group with the addition of Mohammed Gibreal, M.D.
Pascack Valley Medical Group announced that Mohammed Gibreal, M.D. has joined the practice’s cardiology group. As a noninvasive cardiologist practicing in community hospitals and tertiary care medical centers, Dr. Gibreal has vast experience delivering care in inpatient and outpatient settings.
Seven Hackensack Meridian Health Medical Centers Nationally Recognized for their Commitment to Providing High-Quality Heart Failure Care
Seven Hackensack Meridian Health medical centers have received American Heart Association Get With The Guidelines® – Heart Failure Quality Achievement Awards. The awards recognize the medical centers’ commitment to improving outcomes for patients with heart failure, reducing patient readmissions and providing more healthy days at home.
Mayo Clinic Healthcare expert shares heart failure signs, risk factors people may not be aware of
Heart failure may seem like a disease of advanced age, but it can develop at any time in life. And, in many cases, it can be prevented or treated. In this expert alert, Gosia Wamil, M.D., Ph.D., a cardiologist at Mayo Clinic Healthcare in London, explains risk factors, symptoms that people may not be aware of and how heart failure is treated.
When heart-assisting implants could save a life, patients who are Black or female don’t get them as often
Black people and women with severe heart failure who might be good candidates for surgery to implant a heart-assisting device have a lower chance of actually getting that operation than white patients, or male patients, a new study finds.
Initiative Addresses Challenges of Managing Heart Failure
A pilot program at The Brookdale University Hospital and Medical Center, Brooklyn, New York — designed to help patients manage heart failure after hospital discharge — quickly improved patient adherence to their medication and treatment plan, and resulted in fewer readmissions among the initial 47 patients.
MedStar Washington Hospital Center Again Named Among Nation’s Top 50 for Heart Care
MedStar Washington Hospital Center has again achieved national ranking for Cardiology & Heart Surgery in the 2022-23 U.S. News & World Report “Best Hospitals” rankings. It moved up to No. 28, from No. 30 last year. It is the only nationally recognized heart program of its kind in the Washington metropolitan area. MedStar Washington also earned “high performing” ratings in cancer, gastroenterology & GI surgery, Urology, and in 12 common procedures and conditions.
Heart muscle scarring found in patients with hypertension are associated with worse outcomes
First-of-its-kind study by NHCS researchers shows adverse association between heart muscle scarring (also known as myocardial fibrosis) and patients with hypertension, detected non-invasively using cardiac magnetic resonance imaging (CMR).
Loss of Male Sex Chromosome Leads to Earlier Death for Men
The loss of the male sex chromosome as many men age causes the heart muscle to scar and can lead to deadly heart failure, new research from the University of Virginia School of Medicine shows.