Cal State Fullerton antibiotic-resistance researcher María Soledad Ramírez and her students have discovered a promising new therapeutic to treat Acinetobacter baumannii, a superbug commonly found in hospitals and resistant to many antibiotics.
Lower income breast cancer patients often struggle to afford life’s necessities such as housing, transportation and utilities due to direct and incidental costs related to their treatment, according to a new analysis by Susan G. Komen®.
Spain is the first country in the world to have this technology
• Results showing the clinical utility of the test were published in
Lancet Oncology and the Journal of National Cancer Institute
• The test is now available to oncologists and pathologists and will
benefit an estimated 24,000 patients each year in Spain
BACKGROUNDHeart failure (HF) is a global health problem characterized by impaired heart function. Cardiac remodeling and cell death contribute to the development of HF. Although treatments such as digoxin and angiotensin receptor blocker dr
Antibiotic resistant bacteria are a threat to human lives, and yet the development of new drugs to treat bacterial infections is slow.
Eighteen U.S. states have laws that allow insurance companies to deny health care payments to treat people who were intoxicated when they sustained an injury, despite evidence showing that these laws prevent people from receiving treatment for alcohol use disorder and shift costs from insurance companies to the health care system, the government, individuals and families.
As we honor lymphoma awareness month, what do you want our patients and families to pause and remember?Lymphoma is a disease which can strike any one of us, young and old, at any time.
Even the best treatment approaches for Parkinson’s disease are inadequate if they do not address patients’ feelings of social rejection, isolation, loneliness and other psychosocial effects of stigma, according to a report from experts specializing in Parkinson’s and other movement disorders.
Although immunotherapies have shown promise in treating non-small cell lung cancer (NSCLC), many patients still do not respond well, and those who do may eventually develop resistance.
Researchers seeking to improve the use of radium-223 to target cancer cells investigated how the isotope interacts with two chelators, macropa and DOTA. Experiments and computer-driven models discovered that macropa is the strongest chelator for binding radium identified so far.
David M. Golombos, MD, addresses prostate cancer topics
Charles C. Park, M.D., Ph.D., and Jon I. McIver, M.D., neurosurgeons with The Minimally Invasive Brain and Spine Center at Mercy, are featured guests on Mercy’s monthly talk show, “Medoscopy”, September 20th-21st at 5:30 p.m. EST.
Systemic sclerosis is the scaring of multiple organs within the body resulting in difficulty in functioning for these organs. The disease can become deadly if the organ scaring isn’t treated properly. Researchers at the University of Michigan Health System have identified a protein in the disease that may be a new target for treatment.
Access to care affects people with epilepsy worldwide. Bringing care closer to home can help—but what about bringing care inside the home?
The presence of peers is a key prompt for alcohol cravings among young people, according to a new study in Alcohol: Clinical & Experimental Research. When certain settings, people, or items—a bar, a friend, a glass—are paired with alcohol, they can become conditioned cues, eliciting drinking cravings. These learned reactions are associated with alcohol use disorder (AUD), treatment outcomes, and relapse. Adolescents and emerging adults are particularly susceptible to peer influence. In real-world settings, studies have found that the presence of peers predicts young people’s intensifying drinking cravings at the moment. In laboratory studies, however, peer influence is largely absent, potentially limiting the usefulness of their findings. Better understanding peers as alcohol cues could inform more effective AUD prevention and treatment programs. For the current study, researchers from Brown University, RI, evaluated alcohol cravings among youth in the human laboratory, using drinking-
New AI tool accurately predicts both overall survival and disease-free survival after colorectal cancer diagnosis.
The model uses visual markers on pathology images to glean insights into a tumor’s genomic profile and predicts tumor behavior, disease progression, treatment response.
The new model could help augment clinical decision-making.
Because the AI tool relies on images alone, it could be particularly valuable for hospitals lacking the technology or expertise to perform sophisticated genomic profiling of tumor tissues.
Treatment is scarce for functional neurological disorder (FND), which requires a multidisciplinary approach. A special report published in the March/April issue of Harvard Review of Psychiatry (HRP) aims to show clinicians and institutions around the world what is needed to establish effective community treatment programs for FND, as well as hospital inpatient and outpatient interventions, in their own health care settings. HRP is published in the Lippincott portfolio by Wolters Kluwer.
A research team from the Faculty of Medicine and Faculty of Engineering, Chulalongkorn University has jointly developed AICute, an innovative program to assess the chances of stroke caused by heart disease (Ischemic Stroke), aimed at helping hospitals that lack cardiologists to enhance the effectiveness of stroke treatment, reduce congestion in hospitals and medical schools.
A new screening instrument has the potential to more accurately identify fetal alcohol spectrum disorder (FASD), reducing missed and erroneous diagnoses in affected children and facilitating treatment and support, a new study suggests. Prenatal alcohol exposure (PAE) is a known cause of birth and growth defects and neurobehavioral issues.
The Faculties of Medicine and Science, Chulalongkorn University, in collaboration with University College London (UCL), the United Kingdom, together with industrial partner have developed Eartest by Eartone Application that examines hearing with Thai words processing that the public can use to screen dementia by themselves before consulting physicians to help prevent and reduce future risk of dementia.
The treatment is the first therapy to mitigate heart muscle damage after catheter-based intervention and could increase long-term survival for heart attack patients.
The American College of Rheumatology (ACR) released a summary of its new guideline for Exercise, Rehabilitation, Diet and Additional Integrative Interventions for Rheumatoid Arthritis. This is the first ACR guideline about an Integrative Approach to RA.
Children aged 8 years or younger should be considered a group at high risk for more severe monkeypox disease, reports The Pediatric Infectious Disease Journal, the official journal of The European Society for Pediatric Infectious Diseases. The journal is published in the Lippincott portfolio by Wolters Kluwer.
This model can be used by researchers to discover targets for treatments that improve walking, cognitive, coordination and visual disabilities in MS.
When a high school or college student consults a physician about a sport-related concussion, their age, severity of symptoms, number of previous concussions, and family history of psychiatric disorders predict whether they can be released to supervision by an athletic trainer or will need additional medical care, according to an article in the Clinical Journal of Sports Medicine. The journal is published in the Lippincott portfolio by Wolters Kluwer.
The American College of Rheumatology (ACR) released a summary of its updated guideline for the Prevention and Treatment of Glucocorticoid-Induced Osteoporosis. New osteoporosis medications and new literature have become available since the last ACR treatment guideline was published in 2017.
Researchers from the University of Georgia have discovered a potential treatment for Chagas disease, marking the first medication with promise to successfully and safely target the parasitic infection in more than 50 years. Human clinical trials of the drug, an antiparasitic compound known as AN15368, will hopefully begin in the next few years.
Drinkers’ mood shifts and exposure to alcohol-related cues — beer cans, bars, and drinking buddies — contribute to alcohol cravings in opposite ways for men and women, a new study suggests. The findings have implications for how men and women develop dangerous drinking habits and ways that this might be prevented or treated. Various theories link alcohol use to positive and negative emotions: drinking to either enhance good mood or cope with stress, potentially becoming a self-reinforcing cycle. Studies have yielded mixed findings, however, suggesting that mood interacts with subconscious cognitive processes to prompt alcohol-seeking.
The Faculty of Veterinary Science, Chulalongkorn University has researched and replicated “hydroxy-xanthones”, the vital extracts rich in antioxidants found in mangosteen peels that kill germs and halt infections in the intestinal mucosa. It hopes to expand to include health products for humans and animals in the future.
TransMED analyzes patient data from similar diseases across multiple sources to understand COVID-19 patient outcome risk factors.
Hereditary hair loss, also known as androgenetic alopecia or pattern hair loss, is the most common form of hair loss in both men and women, affecting millions of people worldwide.
Introducing a new dimension for consultations with those suffering from depression by the Department of Mental Health and the DMIND AI Innovation from Chula’s Faculties of Medicine and Engineering that provides screening for depression through the Mor Prom Application with greater accuracy, accessibility, and convenience thus reducing the burdens on medical practitioners and psychologists in taking care of patients with depression.
The first bladder cancer drug targeting a cancer-driving gene mutation has been used relatively little despite its clear efficacy in a clinical trial, suggests a JAMA Oncology study led by the University of Pennsylvania. Researchers analyzed a large, nationwide database of cancer cases and found that bladder cancer patients potentially eligible for erdafitinib (Balversa) treatment, fewer than half had a record of being tested for the relevant gene mutation. Of those who were tested and found to have the mutation, fewer than half received the treatment.
Chula opens a state-of-the-art innovation center for veterinary students to practice their clinical skills with a simulated and modern lab classroom to hone students’ skills and develop their expertise and a space for international training to promote veterinary and medical education.
New research presented this week at ACR Convergence, the American College of Rheumatology’s annual meeting, shows that allopurinol and febuxostat may effectively lower urate levels when used in a treat-to-target approach. Importantly, both urate-lowering therapies were very effective with 90% of patients reaching target urate levels. Additionally, both appeared safe, with no evidence of increased cardiovascular toxicity.
IU study illustrates the need to treat mental health problems and smoking together.
Medical results show that music therapy can lower blood pressure, relieve pain during chemotherapy and dialysis, as well as stimulate the elderly brain. The Faculty of Fine and Applied Arts, Chulalongkorn University is offering a Music Therapy Program aiming to heal the ever-increasing patients with various chronic diseases in society.
A new Cornell study has found the antimicrobial properties of certain stem cell proteins could offer a potential treatment to reduce infection in skin wounds.
Several innovative, minimally invasive techniques used over the past 12 months to improve Carter’s health — including a first-of-its-kind procedure performed in the United States — means he can finally go home.
St. Jude Children’s Research Hospital scientists have developed a highly efficient method to address a major challenge in biology—identifying the genetic ‘switches’ that regulate gene expression.
April 9, 2021 – Chula holds the 4th CHULA the Impact Seminar entitled “World–Class Innovative Prosthesis Made by Thais” showcasing the capabilities of Chula researchers from Chula Engineering Enterprises
An international, open-label Phase 3 study, co-led by Susanna McColley, MD, from Ann & Robert H. Lurie Children’s Hospital of Chicago, found that a regimen of three drugs (elexacaftor/tezacaftor/ivacaftor) that targets the genetic cause of cystic fibrosis was safe and effective in 6-11-year-olds with at least one copy of F508del mutation in the CFTR gene, which is estimated to represent almost 90 percent of the cystic fibrosis population in the United States.
Chula’s Faculty of Pharmaceutical Science has developed its very own “Mangrove–Tree (Samae–Talay) extract treatment for hair loss and baldness problem” which received the Innovation Award 2021 in Chemical Science and Pharmacy (Very Good Level) from the National Research Council of Thailand (NRCT), and is expected to hit the market this year.
A clinical study led by Dr. Jordan Feld, a liver specialist at Toronto Centre for Liver Disease, University Health Network (UHN), showed an experimental antiviral drug can significantly speed up recovery for COVID-19 outpatients – patients who do not need to be hospitalized. This could become an important intervention to treat infected patients and help curb community spread, while COVID-19 vaccines are rolled out this year.
Researchers at Canada’s McMaster University have established in lab settings that a novel combination of two forms of immunotherapy can be highly effective for treating lung cancer, which causes more deaths than any other form of cancer.
Researchers from Mount Sinai and the National Center for Geriatrics and Gerontology in Japan have identified new molecular mechanisms driving late-onset Alzheimer’s Disease.
Monitoring how patients with multiple sclerosis or other degenerative diseases use their smartphones could provide valuable information to help get them better treatment. In the journal Chaos, researchers used an app to record the keystroke dynamics of a control group and those of subjects in various stages of MS treatment. In doing so, they observed changes in the way people with MS typed that were not seen in subjects who did not have the disease.
Study finds that in a diverse, global patient population, a minimal monitoring (MINMON) approach to hepatitis C treatment was safe and achieved comparable sustained virologic response (SVR) to current standard of care.
Researchers have found that a more intensive, less frequent drug regimen with currently available therapeutics could cure the infection that causes Chagas disease
James J. Collins, Ph.D., an innovator in synthetic biology whose ideas have contributed to novel diagnostics and treatments targeting infections and complex diseases, has been awarded the 2020 Dickson Prize in Medicine, the University of Pittsburgh School of Medicine’s highest honor.