Penny for Your Thoughts? Master Copper Regulator Discovery May Offer Alzheimer’s Clues

A groundbreaking study using a tiny roundworm could pave the way for new treatments for neurodegenerative disorders. Researchers have linked the worm gene swip-10 to copper regulation – a vital element for brain health found in everyday items like wiring and cookware. Understanding the roles of swip-10 and MBLAC1, a protein involved in processing cellular materials, could lead to the development of effective medications and opens new avenues for advancing brain disease treatments.

National Academy of Medicine Selects FAU for Substance Use, Opioid Crises Collaborative

FAU joins the National Academy of Medicine’s Action Collaborative on Combating Opioid Crises. This pilot project, involving more 80 organizations, aims to enhance coordination and address addiction challenges through collaboration among public, private and nonprofit sectors.

Uncontrolled Hypertension: The Old ‘Silent Killer’ is Alive and Well

High blood pressure affects about 45% of U.S. adults. In the 1970s, only about 50% of patients were aware of their hypertension. Today, 54% are aware of their high blood pressure, 40% are actively treated and 21% are actively controlled. As such, researchers alert health care providers that the old “silent killer” is alive and well.

Advancing regenerative medicine therapies

University and community guests recently gathered to celebrate the 7,700 square-foot Good Manufacturing Practice facility’s grand opening in Hewitt Hall’s basement on the UC Irvine campus. Although the highly sterile environment remains off-limits for tours, the gala highlighted its importance to the campus, the UC system and the local community.

ASCO: Proton therapy demonstrates advantages in Phase III head and neck cancer trial

According to preliminary data from a multi-institution Phase III trial led by researchers at The University of Texas MD Anderson Cancer Center, intensity modulated proton therapy (IMPT) achieved similar clinical outcomes and offered significant patient benefits when compared to traditional intensity modulated radiation therapy (IMRT) as part of chemoradiation treatment for patients with oropharyngeal (head and neck) cancer.

Promising New Treatment for Patients with HR+ HER-2 Negative Metastatic Breast Cancer

New research from Yale Cancer Center reveals first-of-its-kind data from a phase I study in patients with hormone receptor positive HER2-negative metastatic breast cancer. The results, which assess the safety and efficacy of a treatment known as PF-07248144, offer new hope for treating this aggressive type of breast cancer.

FAU Researchers Receive $1M in FDOH Grants to Fight Alzheimer’s Disease

With this funding, FAU researchers will shed light on the biological functions of Alzheimer’s disease (AD) by taking advantage of synthetic chemistry strategies; provide an innovative online screening tool for older drivers with cognitive decline; and gain a deeper understanding of the role of brain cholesterol in AD.

Study Examines U.S. Public Opinion of ‘Would-be’ Mass Shooters

A first-of-its-kind study sheds light on public opinion about would-be mass shooters, particularly regarding their mental health status. Willingness to “see something” and “say something,” especially when loved ones or associates are involved, hinges on whether the informant believes the criminal justice system will handle the situation effectively and fairly.

JMIR Dermatology Invites Submissions on Diversity in Dermatology

JMIR Publications is pleased to announce a new theme issue titled “Diversity in Dermatology” in JMIR Dermatology. The premier, peer-reviewed journal is indexed in Sherpa Romeo, Scopus, DOAJ, CABI, and PubMed Central/PubMed and is the official journal of the International Society of Digital Health in Dermatology (ISDHD).

Podcast: Experts in Health: The menopause and the controversial ‘male menopause’

Professor Eef Hogervorst, Professor of Biological Psychology at Loughborough University, sits down to discuss the factors influencing the menopause, what the best treatment options are, the relationship between oestrogen and dementia, and the controversies surrounding the andropause (the ‘male menopause’).

New treatment for a rare and aggressive cancer improves survival rates in breakthrough clinical trial

An innovative treatment significantly increases the survival of people with malignant mesothelioma, a rare but rapidly fatal type of cancer with few effective treatment options, according to results from a clinical trial led by Queen Mary University of London.

Prof. Dr. Thanyavee Puthanakit, National Outstanding Researcher in Medical Science, with Clinical Research on the Treatment and Prevention of HIV in Youth

Prof. Dr. Thanyavee expressed her appreciation and honor for receiving the Outstanding Researcher Award.

New treatment developed to dramatically slow down the progression of blindness-causing retinal diseases

The Korea Institute of Science and Technology (KIST) announced that Dr. Maesoon Im of the Brain Science Institute, together with Prof. Seung Ja Oh of Kyung Hee University and Prof. Kangwon Lee of Seoul National University, successfully incorporated anti-inflammatory drugs into a hydrogel to suppress inflammation in the retina and effectively deliver the drugs to the inflamed area.

Residents of Rural ‘Glades’ Take a ‘Leap of Faith’ to Combat Dementia

Compared to urban dwellers, racially/ethnically diverse older adults face up to an 80 percent greater risk of cognitive impairment in older age, and 2.5 times potentially preventable Alzheimer’s-related (ADRD) hospitalizations.

NIH grants support UCLA and Charles Drew University researchers’ efforts to end HIV epidemic

The National Institutes of Health (NIH) has granted $2.1 million to UCLA’s Center for HIV Identification, Prevention, and Treatment Services (CHIPTS) and the UCLA-CDU Center for AIDS Research (CFAR) to support four research projects and an implementation science consultation hub.

Brain tumor treatment by targeting TUG1, a gene that controls replication stress

A new study has unravelled a crucial link between how cancer cells cope with replication stress and the role of Taurine Upregulated Gene 1 (TUG1). By targeting TUG1 with a drug, the researchers were able to control brain tumor growth in mice, suggesting a potential strategy to combat aggressive brain tumors such as glioblastomas.

Palex and Inbiomotion introduce pioneering test to aid oncologists in predicting recurrence and survival rates in breast cancer patients

Spain is the first country in the world to have this technology
• Results showing the clinical utility of the test were published in
Lancet Oncology and the Journal of National Cancer Institute
• The test is now available to oncologists and pathologists and will
benefit an estimated 24,000 patients each year in Spain

U.S. States Maintain Outdated Laws That Create Barriers to Screening and Treatment for Alcohol Use Disorder

Eighteen U.S. states have laws that allow insurance companies to deny health care payments to treat people who were intoxicated when they sustained an injury, despite evidence showing that these laws prevent people from receiving treatment for alcohol use disorder and shift costs from insurance companies to the health care system, the government, individuals and families.

“Stereotyped, devalued and shunned.” Experts address treating the stigma of Parkinson’s disease

Even the best treatment approaches for Parkinson’s disease are inadequate if they do not address patients’ feelings of social rejection, isolation, loneliness and other psychosocial effects of stigma, according to a report from experts specializing in Parkinson’s and other movement disorders.