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Two University of Colorado Cancer Center researchers have received a five-year R01 Award for $497,893 per year from the National Institutes of Health (NIH) to study a potential new drug treatment for salivary gland cancer. The award is part of an inter-campus collaboration between Antonio Jimeno, MD, PhD, co-leader of the Developmental Therapeutics Program, and Tin Tin Su, PhD, co-leader of the Molecular and Cellular Oncology Program.

Research Results

Cancer Patients Who Are Most Worried About Finances Shown to Have Worse Outcomes

March 9, 2021 sarah Jonas Cancer Treatment, Finances, Financial toxicity, Head And Neck Cancer

Cancer treatment is likely to affect every aspect of a patient’s life — their activities, relationships, eating habits, mental health, physical health and comfort, financial wellbeing. And when financial concerns weigh heavily on an individual who is in treatment for cancer, they can affect the outcome of that treatment. New research from Roswell Park Comprehensive Cancer Center provides the first evidence that a cancer patient’s level of financial worry as they begin treatment predicts how likely it is that their treatment will be successful.

Research Results

Behaviors Surrounding Oral Sex May Increase HPV-Related Cancer Risk

January 14, 2021 sarah Jonas Head And Neck Cancer, HPV, Human Papillomavirus, Johns Hopkins Kimmel Cancer Center, oropharyngeal cancer

A wide breadth of behaviors surrounding oral sex may affect the risk of oral HPV infection and of a virus-associated head and neck cancer that can be spread through this route, a new study led by researchers at the Johns Hopkins Kimmel Cancer Center suggests. These findings add nuance to the connection between oral sex and oropharyngeal cancer — tumors that occur in the mouth and throat — and could help inform research and public health efforts aimed at preventing this disease.

Research Results

Telemedicine Use During COVID-19 Shows Access Disparity Among Head and Neck Cancer Patients

December 2, 2020 sarah Jonas Communications, COVID-19, Head And Neck Cancer, Otolarygology, socioeconomic disparities, Telemedicine, Virtual Visits

Retrospective research by Henry Ford otolaryngologists found telemedicine use disparity among head and neck cancer patients during start of COVID-19 pandemic.

Announcement

Henry Ford Health System is the First in Michigan to offer da Vinci Single Port Robotic Surgery System

November 19, 2020 sarah Jonas Cancer, Head And Neck Cancer, Henry Ford Cancer Institute, Henry Ford Health System, Henry Ford Hospital, Minimally Invasive Surgery, prostate cancer

Henry Ford Health System is the first in Michigan to offer the da Vinci SP® robotic surgery system, which requires only a single small incision for its surgical instruments and allows for greater control and access in narrow surgical spaces.

Announcement

Mass Eye and Ear Capital Campaign Concludes with $252 Million Raised to Advance Research and Patient Care

October 29, 2020 sarah Jonas Head And Neck Cancer, Hearing Loss, Vision Loss

Mass Eye and Ear is proud to announce the successful conclusion of its historic campaign, “Bold Science. Life-Changing Cures.” which raised $252M from philanthropy to advance research to treat and cure diseases of vision, hearing, and the head and neck.
The campaign was led by co-chair Wyc Grousbeck, Boston Celtics CEO and Lead Owner and former Chairman of Mass Eye and Ear.

Research Results

Axitinib Improves Survival for Patients with Incurable Head and Neck Cancer

October 20, 2020 sarah Jonas Cancer, Clinical Trials, Head And Neck Cancer

A new phase 2 clinical trial found the drug axitinib was able to extend the lives of patients with incurable head and neck cancer by several months, and also identified a subset of patients with a specific mutation for whom the drug is likely to work best.

Expert Pitch

HPV Vaccinations During Global Pandemic

August 5, 2020 sarah Jonas anal cancer, Cancer Prevention, Cervical Cancer, COVID-19, Head And Neck Cancer, HPV, HPV-associated cancer, Human Papilloma Virus, Infectious Disease, Oral Cancer, Pandemic, Pediatrics, Public Health, Sexually Transmitted Infections, STI, Vaccination, Vaccines

Human papillomavirus (HPV) is the most common sexually transmitted infection and the cause of most cervical cancers, and some vaginal,

Research Results

Precision Medicine Identifies Key Recurring Mutation in Head and Neck Cancers

July 30, 2020 sarah Jonas Cancer, ear, nose and throat, Genetics, Head And Neck Cancer, Oncology, Precision Medicine

Researchers at UC San Diego School of Medicine and Moores Cancer Center report that an investigational drug candidate called tipifarnib showed promise in treating key recurring mutation in head and neck cancers.

Feature

10 Things to Know About HPV and Throat Cancer

July 27, 2020 sarah Jonas Cancer Prevention, Head And Neck Cancer, HPV, Hpv Vaccine, oropharyngeal cancer, oropharynx cancer

As we observe World Head and Neck Cancer Day 2020 (July 27), nationally known expert Tom Thomas, MD, MPH, has set out to clear up misunderstandings about how one type of head and neck cancer is related to human papillomavirus (HPV), which has historically been thought of primarily as a cause of cervical cancer. Dr. Thomas is medical director, Head and Neck Reconstructive Surgery and Transoral Robotic Surgery, Leonard B. Kahn Head and Neck Cancer Institute at Atlantic Health System’s Morristown Medical Center and Carol G. Simon Cancer Center. He is one of the leaders of the Atlantic HPV Center.

Feature

Cancer Clinical Trials Tested, Continue During COVID-19 Pandemic

July 23, 2020 sarah Jonas Cancer, Cancer Therapeutics, Clinical Trials, COVID-19 and Cancer, Head And Neck Cancer, OB GYN

During the COVID-19 pandemic, Moores Cancer Center at UC San Diego Health continues to offer potentially lifesaving treatment through cancer clinical trials.

Research Results

Researchers ID new target in drive to improve immunotherapy for cancer

July 21, 2020 sarah Jonas Cancer Stem Cells, Head And Neck Cancer, Immunotherapy

Researchers at the UCLA Jonsson Comprehensive Cancer Center and UCLA School of Dentistry have identified a potential new combination therapy to treat advanced head and neck squamous cell carcinoma, the most common type of head and neck cancer.

Research Results

Adoptive T-cell therapy ADP-A2M4 targeting MAGE-A4 shows early activity in patients with advanced solid tumors

May 29, 2020 sarah Jonas Head And Neck Cancer, Immunotherapy, Lung Cancer

The adoptive T-cell therapy ADP-A2M4, which is engineered to express a T-cell receptor (TCR) directed against the MAGE-A4 cancer antigen, achieved responses in patients with multiple solid tumor types, including synovial sarcoma, head and neck cancer and lung cancer, according to results from a Phase I clinical trial led by researchers at The University of Texas MD Anderson Cancer Center.

Announcement

New Information from NCCN on Overcoming Challenges for People with Head and Neck Cancers

May 26, 2020 sarah Jonas Head & Neck Cancer, Head And Neck Cancer, Head And Neck Cancers, Health Literacy, HPV vaccination, Hpv Vaccine, HPV-related cancer, HPV-related cancers, HPV-related throat cancer, Human Papilloma Virus, Nasopharyngeal, National Comprehensive Cancer Network, NCCN, NCCN Foundation, NCCN Guidelines for Patients, oropharyngeal cancer, oropharyngeal squamous cell carcinoma, Patient Information

Newly-completed series of patient guidelines from National Comprehensive Cancer Network (NCCN) shares expert advice with patients and caregivers on treatment and prevention for most common head and neck cancers, including some that are HPV-related.

Research Results

Absent p53, oral cancers recruit and reprogram nerves to fuel tumor growth

February 12, 2020 sarah Jonas Cancer, Head And Neck Cancer, Md Anderson, MD Anderson Cancer Center, MD Anderson Cancer Center Houston, Tumor

Loss of an important tumor-suppressing gene allows head and neck cancer to spin off signals to nearby nerves, changing their function and recruiting them to the tumor, where they fuel growth and cancer progress.

Research Results

Gaps in Cure Rate Appear Linked to Race and Insurance Status for a Common HPV-Related Cancer, According to New Research

February 6, 2020 sarah Jonas Head & Neck Cancer, Head And Neck Cancer, HPV, HPV-related cancers, jnccn, JNCCN - Journal of the National Comprehensive Cancer Network, National Comprehensive Cancer Network, NCCN, Racial Disparities

Largest population-based analysis on factors that affect survival outcomes for HPV-positive oropharyngeal squamous cell carcinoma of the head and neck (SCCHN) find significant racial and socioeconomic disparities, according to new study in JNCCN-Journal of the National Comprehensive Cancer Network.

Research Results

Botanical drug is shown to help patients with head and neck cancers

February 5, 2020 sarah Jonas Cancer Research, Head And Neck Cancer, Turmeric, UCLA

In a UCLA-led phase I clinical trial, a new plant-based drug called APG-157 showed signs of helping patients fight oral and oropharyngeal cancers. These cancers are located in the head and the neck.
APG-157 is made up of multiple compounds produced by plants, including curcumin. UCLA Jonsson Comprehensive Cancer Center researchers found that treatment with this botanical drug resulted in high concentrations of curcumin and its byproducts circulating in the blood and absorbed by tumor tissues within three hours after being taken orally.