Enclosing Radiation-Loaded Particles to Better Seek and Destroy Cancer

When medical isotopes are used to treat diseases, they emit large amounts of energy that makes it hard to keep them near the target cells. Researchers are now testing a way to enclose isotopes in tiny pieces of biodegradable material that will keep the isotopes at treatment sites, ensuring that their energy can kill diseased cells with little effect on surrounding cells.

How a plant virus could protect and save your lungs from metastatic cancer

Using a virus that grows in black-eyed pea plants, researchers developed a new therapy that could keep metastatic cancers from spreading to the lungs, as well as treat established tumors in the lungs.

Innovation in Cancer Prevention – Bio-robots Transporting Cordyceps Extract

Chula researchers celebrate the success of Active Targeting, a revolutionary innovation in the medical industry using bio–robots to deliver targeted cordyceps extract to halt cancer with reduced side effects.

This crystal impurity is sheer perfection

Scientists at Berkeley Lab and UC Berkeley have developed a nanoparticle composite that grows into 3D crystals. The new 3D-grown material could speed up production and eliminate errors in the mass manufacturing of nanoscale photonics for smart buildings or actuators for robotics.

Genetically Engineered Nanoparticle Delivers Dexamethasone Directly to Inflamed Lungs

Nanoengineers at the University of California San Diego have developed immune cell-mimicking nanoparticles that target inflammation in the lungs and deliver drugs directly where they’re needed. As a proof of concept, the researchers filled the nanoparticles with the drug dexamethasone and administered them to mice with inflamed lung tissue. Inflammation was completely treated in mice given the nanoparticles, at a drug concentration where standard delivery methods did not have any efficacy.

Study: Turning a coronavirus protein into a nanoparticle could be key to an effective COVID-19 vaccine

One of the proteins on the virus – located on the characteristic COVID spike – has a component called the receptor-binding domain, or RBD, which is its “Achilles heel.” That is, he said, antibodies against this part of the virus have the potential to the neutralize the virus.

A first-of-its-kind catalyst mimics natural processes to break down plastic and produce valuable new products

A team of scientists led by the U.S. Department of Energy’s Ames Laboratory has developed a first-of-its-kind catalyst that is able to process polyolefin plastics, types of polymers widely used in things like plastic grocery bags, milk jugs, shampoo bottles, toys, and food containers.

NEW DRUG CARRIER SYSTEMS

A University of Delaware research team has devised tiny cargo-carrying systems many times smaller than a human hair, made from molecules called peptides that help provide structure for cells and tissues. The team has reported advances in the nanoparticle design that allow them to control the shape of the nanoparticles to allow them to better bind to tissue in the body and stay in a particular location.

Determining Effective Magnetic Moment of Multicore Nanoparticles

Most commercial nanoparticles do not possess a single magnetic core but have small magnetic crystals called crystallites. The important question is how these crystallites behave inside a multicore nanoparticle and how they respond to an applied magnetic field. In the Journal of Applied Physics, researchers compare the effective magnetic moments of different multicore nanoparticle systems and shows that they are magnetic-field dependent. The paper’s findings are important for researchers optimizing magnetic nanoparticles for various applications.

Nanosize Device ‘Uncloaks’ Cancer Cells in Mice And Reveals Them to The Immune System

Scientists at Johns Hopkins report they have designed and successfully tested an experimental, super small package able to deliver molecular signals that tag implanted human cancer cells in mice and make them visible for destruction by the animals’ immune systems. The new method was developed, say the researchers, to deliver an immune system “uncloaking” device directly to cancer cells.

Articles on Chronic Hexavalent Chromium Exposure, Titanium Dioxide Nanoparticles, and Bisphenol A Featured in December 2019 Toxicological Sciences

The December 2019 issue of Toxicological Sciences features research on the leading edge of toxicology, including in the areas of carcinogenesis, developmental and reproductive toxicology, and more.

Nanoparticle Drug Delivery Provides Pain Relief and More Effective Opioid Alternative in Animal Study

An international team of researchers has used nanoparticles to deliver a drug—one that previously failed in clinical trials for pain—into specific compartments of nerve cells, dramatically increasing its ability to treat pain in mice and rats. The findings are published Nov. 4 in Nature Nanotechnology.

Living on the Edge: How a 2D Material Got Its Shape

A team of scientists led by the Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab) has gained valuable insight into 3D transition metal oxide nanoparticles’ natural “edge” for 2D growth.