The Centers for Disease Control and Prevention (CDC) yesterday released its long-awaited updated Guideline for Prescribing Opioids for Chronic Pain. The American Society of Anesthesiologists (ASA) and its members – who are experts in pain medicine and have led the…
COLUMBUS, Ohio – The first year of the COVID-19 pandemic saw a 113% increase in the “Years of Life Lost” among adolescents and young people in the United States due to unintentional drug overdose, according to researchers at The Ohio State University Wexner Medical Center and College of Medicine.
In a Johns Hopkins Medicine study of patients who underwent adult spinal deformity (ASD) surgery, preoperative opioid use and pain duration of four or more years were independently associated with higher odds of chronic post-surgery opioid use.
Prenatal exposure to opioids had been linked to a range of adverse outcomes in infants, including poor fetal growth, low birthweight, possible congenital defects and a higher risk of admission to neonatal intensive care. Less information is known, however, on how developmental opioid exposure shapes an infant’s microbiome and how that influence, in turn, may trigger neurological or behavioral effects later in life.
Members of racial and ethnic minority groups were less likely to obtain prescriptions to treat opioid addiction during the COVID-19 pandemic, according to a study by researchers at Rutgers and Indiana University.
CHICAGO – “Despite the prevalence and societal costs of pain in the United States, investment in pain medication development is low, due in part to poor understanding of the probability of successful development of such medications,” said the authors of a study published Online First in Anesthesiology, the official peer-reviewed journal of the American Society of Anesthesiologists (ASA).
Buprenorphine is a prescription approved by the Food and Drug Administration (FDA) that effectively treats opioid dependence or addiction. But women, as well as Black and Hispanic populations, do not have equal access to this potentially lifesaving medication, new Mayo Clinic research finds.
New UCLA research published in The Journal of Physiology points to a novel treatment for respiratory depression associated with opioid use that administers electrical pulses to the back of the neck, helping patients regain respiratory control following high dosage opioid use. This could offer an alternative to pharmacological treatments, which can cause withdrawal symptoms, heart problems and can negatively affect the central nervous system.
New research finds people who were using buprenorphine obtained without a prescription were more likely to remain in treatment for opioid-use disorder, underscoring need to expand access to this medication.
Treating pregnant women with opioid use disorder can help minimize opioid-related brain abnormalities in their newborns. Led by scientists at Cedars-Sinai, this is the first study to report evidence validating the benefits of using medication for opioid use disorder during pregnancy.
Researchers at Washington University School of Medicine in St. Louis and Saint Louis University found that less than half of Americans who received treatment for opioid use disorder over a five-year period were offered a potentially lifesaving medication. The numbers were even lower for those with what’s known as polysubstance use disorder — when opioid users also misuse other substances.
A study by researchers at Hospital for Special Surgery (HSS) found that the antidepressant duloxetine reduced the use of opioid medication when added to a multimodal pain management regimen after knee replacement surgery. The study appeared in The Journal of Arthroplasty.
Despite the ability of any Michigan pharmacy to dispense medication to combat opioid overdose without writing prescriptions, slightly more than half of pharmacies in the state offer the drug in such a way.
Michael J. Moore, a professor of biomedical engineering at Tulane University School of Science and Engineering, is part of a national study that aims to turn around the statistics on opioid addiction.
Lung surgery patients who utilize a comprehensive, evidence-based enhanced recovery after surgery (ERAS) program require fewer opioid prescriptions when discharged and this effect was sustained over the 4-year study period.
Richard Ausness is a product liability expert and the Stites and Harbison Professor of Law at the University of Kentucky J. David Rosenberg College of Law. He currently teaches Property, Trusts & Estates and Products Liability. His other teaching interests…
The July 30 virtual conference is part of a three-year grant to train clinicians to prescribe medications to treat addiction.
Medical guidelines help doctors understand the best way to treat health conditions. Surprisingly, many doctors do not adhere to them, and this is a problem, according to a new study. People with lower back pain injury miss 11 more days of work in a year when they only receive treatments for lower back pain that are not recommended by medical guidelines compared to people treated according to guidelines.
Now that a key policy regarding prescription of a medication for opioid use disorder has been changed, experts reflect on the remaining challenges standing in the way of more people getting effective medication-assisted treatment, and discuss efforts to overcome those barriers.
A prescribing guideline tailored to patients’ specific needs reduced the number of opioid pills prescribed after major surgery.
DALLAS – Feb. 22, 2021 – Three decades-old antibiotics administered together can block a type of pain triggered by nerve damage in an animal model, UT Southwestern researchers report. The finding, published online today in PNAS, could offer an alternative to opioid-based painkillers, addictive prescription medications that are responsible for an epidemic of abuse in the U.S.
A pain management regimen comprised mostly of over-the-counter medication reduced opioid exposure in trauma patients while achieving equal levels of pain control, according to a new study by physician-researchers at UTHealth.
Opioid receptors in the inner ear can cause partial or full hearing loss, says Rutgers study
Opioid users can develop chronic inflammation and heightened pain sensitivity. These side effects might stem from the body’s own immune system, which can make antibodies against the drugs. The researchers will present their results at the American Chemical Society Fall 2020 Virtual Meeting & Expo.
Johns Hopkins researchers have demonstrated that behavior therapy that exposes people to memories of their trauma doesn’t cause relapses of opioid or other drug use, and that PTSD severity and emotional problems have decreased after the first therapy session.
Of nearly 6,500 commercially insured patients treated in EDs nationwide for an overdose or other opioid-related medical complications, only 16 percent accessed opioid use disorder (OUD) medications or another form of treatment within three months of the ED visit.
• In an analysis of information on US adults initiating hemodialysis, 16% of patients were dispensed a short-acting benzodiazepine, and approximately one-quarter of these patients were also dispensed opioids.
• Among patients with an opioid prescription, being dispensed a short-acting benzodiazepine had a 1.9-fold higher risk of dying over a median follow-up of 16 months compared with patients without a short-acting benzodiazepine.
Many people trying to manage their pain and addiction have lost their support programs due to COVID-19. A Rutgers expert in Emergency Medicine discusses how patients can manage the disease during the coronavirus crisis.
Researchers in the Arizona State University Department of Psychology have shown that chemogenetic activation of the anterior insula restores prosocial behavior in an animal model of opioid addiction and empathy. The findings suggest an important role for the anterior insula in the brain response to addiction.
Saint Louis University School of Medicine is tackling the country’s opioid abuse crisis by training community physicians to recognize and treat addictions.
The massive multidistrict litigation over the nation’s opioid crisis recently reached its conclusion with a $260 million settlement with drug manufacturers. Now, the second phase— focusing on the pharmacy industry’s role in the opioid epidemic—is slated to begin. “This is…
Rural areas have been hit hard by the opioid crisis, but few studies have been done to understand how to improve access to treatment and reduce the overdose death rate in these communities, according to a new study by Rutgers University, the University of Michigan, and Wayne State University.
Complimentary press passes and virtual newsroom access are now available for the Experimental Biology (EB) 2020 meeting, to be held April 4–7 in San Diego.
Only a tiny minority of people at risk for an opioid overdose actually are prescribed a drug that could save their lives, a new study suggests. And the odds of having a dose of the rescue drug were very low among some of the most at-risk groups, including those who had already survived a previous opioid overdose.
Of three possible ways for people to deliver the life-saving antidote naloxone to a person experiencing an opioid overdose, the use of a nasal spray was the quickest and easiest according to research conducted by William Eggleston, clinical assistant professor at Binghamton University, State University of New York, and colleagues at SUNY Upstate Medical University.
A recently published study shows the United States in the grip of several simultaneously occurring opioid epidemics, rather than just a single crisis. The epidemics came to light after the researchers analyzed county-level data on drug overdose deaths. The study highlights the importance of different policy responses to the epidemics rather than a single set of policies.
People in treatment for opioid addiction are more likely to relapse when they become more tolerant of risks, according to a study by Rutgers and other institutions. The findings can help clinicians better predict which patients are most vulnerable.
A computer betting game can help predict the likelihood that someone recovering from opioid addiction will reuse the pain-relieving drugs, a new study shows.
The research team looked at all research on the effects of cannabis use on illicit opioid use during methadone maintenance therapy, which is a common treatment for opioid use disorder, and found six studies involving more than 3,600 participants.
An international team of researchers has used nanoparticles to deliver a drug—one that previously failed in clinical trials for pain—into specific compartments of nerve cells, dramatically increasing its ability to treat pain in mice and rats. The findings are published Nov. 4 in Nature Nanotechnology.
Physicians who received gifts from pharmaceutical companies related to opioid medications were more likely to prescribe opioids to their patients in the following year, according to a new analysis.
Construction workers are more likely to use drugs than workers in other professions, finds a study by the Center for Drug Use and HIV/HCV Research (CDUHR) at NYU College of Global Public Health.
The National Institute on Drug Abuse (NIDA), part of the National Institutes of Health (NIH), awarded a $3.58 million grant to Sanford Burnham Prebys scientist Anthony Pinkerton, Ph.D., to advance a potential treatment for opioid-use disorders, called SBI-553.
A UC Davis research team, led by Vladimir Yarov-Yarovoy and Heike Wulff, will receive a $1.5 million grant from the National Institutes of Health (NIH) to develop a novel class of peptides that are better at treating pain and don’t have the side effects of opioids. The grant is part of the NIH initiative Helping to End Addiction Long-Term (HEAL Initiative).
A new study finds nearly one in three adults with lupus use prescription opioids to manage pain, despite a lack of evidence that opioids are effective for reducing pain from rheumatic diseases.
CBP recently joined forces with DHS S&T for a project called Synthetic Opioid Detection at Speed (SODAS).
Hardly a day goes by without the public being warned about the dangers of opioids. But still, according to the National Institute on Drug Abuse, more than 130 people die every day of opioid overdose and the problem is getting worse. A Houston Methodist pain specialist says new advancements in pain management are giving patients options.
On Sunday, Purdue Pharma, the company that made billions from the sale of OxyContin, filed for bankruptcy days after reaching a tentative settlement with many of the state and local governments suing it over the toll of opioids. Indiana University…
Patients in the United States and Canada are seven times as likely as those in Sweden to receive a prescription for opioid medications after surgery, according to a new multi-institutional study led by researchers from Penn Medicine.
On Monday, an Oklahoma judge ruled Johnson & Johnson must more than half a billion dollars for its role in the state’s opioid crisis. Stefan Kertesz, M.D., an addiction scholar and professor at the University of Alabama at Birmingham School…