Negative side effects of opioids could be coming from users’ own immune systems (video)

Opioid users can develop chronic inflammation and heightened pain sensitivity. These side effects might stem from the body’s own immune system, which can make antibodies against the drugs. The researchers will present their results at the American Chemical Society Fall 2020 Virtual Meeting & Expo.

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Sedative Drug in Combination with Opioids May Be Especially Dangerous

• In an analysis of information on US adults initiating hemodialysis, 16% of patients were dispensed a short-acting benzodiazepine, and approximately one-quarter of these patients were also dispensed opioids.
• Among patients with an opioid prescription, being dispensed a short-acting benzodiazepine had a 1.9-fold higher risk of dying over a median follow-up of 16 months compared with patients without a short-acting benzodiazepine.

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Gaps Remain in Rural Opioid Crisis Research

Rural areas have been hit hard by the opioid crisis, but few studies have been done to understand how to improve access to treatment and reduce the overdose death rate in these communities, according to a new study by Rutgers University, the University of Michigan, and Wayne State University.

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This drug could save their lives, but less than 2% of them get it

Only a tiny minority of people at risk for an opioid overdose actually are prescribed a drug that could save their lives, a new study suggests. And the odds of having a dose of the rescue drug were very low among some of the most at-risk groups, including those who had already survived a previous opioid overdose.

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