To make drugs and their development safer for children, researchers at Aalto University and the pharmaceutical company Novartis have developed a method to help determine safe drug doses more quickly. The new organ maturation model is more data-driven and consequently less prone to bias.
The March edition of SLAS Discovery features the cover article, “Therapeutic and Vaccine Options for COVID-19: Status After 6 Months of the Disease Outbreak” by Christian Ogaugwu (Federal University Oye-Ekiti, Ekiti State, Nigeria ), Dawid Maciorowski, Subba Rao Durvasula, Ph.D., Ravi Durvasula, M.D., and Adinarayana Kunamneni, Ph.D. (Loyola University Medical Center, Maywood, IL, USA).
A first of its kind drug called vosoritide may increase bone growth in children with achondroplasia, the most common form of dwarfism, according to findings from a recent clinical trial published in The Lancet.
The slight decline in drug overdose deaths in 2018 coincides with Chinese regulations on the powerful opioid carfentanil, rather than the result of domestic U.S. efforts to curb the opioid epidemic, a University of Pittsburgh Graduate School of Public Health analysis revealed today.
Johns Hopkins researchers have demonstrated that behavior therapy that exposes people to memories of their trauma doesn’t cause relapses of opioid or other drug use, and that PTSD severity and emotional problems have decreased after the first therapy session.
Memorial Sloan Kettering Cancer Center (MSK) announces its most recent awards and appointments for the institution’s physicians, scientists, nurses, and staff.
Mice that received an injection of a new experimental drug, TAT-DP-2, after a stroke had smaller areas of damage, and their long-term neurological function was better than that of untreated animals.
Scientists at Sanford Burnham Prebys Medical Discovery Institute, the University of Hong Kong, Scripps Research, UC San Diego School of Medicine, the Icahn School of Medicine at Mount Sinai and UCLA have identified 30 existing drugs that stop the replication of SARS-CoV-2, the virus that causes COVID-19. The study was placed on bioRxiv (pronounced “bio-Archive”), an open-access distribution service for preprints of life science research.
“Under-representation of Asian populations in genetic studies has meant that medical relevance for more than half of the human population is reduced,” one researcher said.
A collaboration between scientists at Rutgers University and The Scripps Research Institute led to the discovery of a small molecule that may slow down or stop the progression of Parkinson’s disease.