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UrduMoffitt Cancer Center researchers have developed a novel reagent that enhances the precision of drug synthesis. This innovative method, published in Nature Communications, introduces a new sulfur fluoride exchange (SuFEx) reagent that allows for highly controlled production of crucial sulfur-based molecules, including sulfinamides, sulfonimidamides and sulfoximines.
Tag: Medical Research
By Mimicking Cicada Wings, Scientists Are Investigating New Ways to Keep Patients Safe
Cicada’s cries ring out in the hot air and their discarded exoskeletons decorate tree branches in the southeast and midwest United States at the height of summer. While their ability to emerge in huge numbers is astounding, they have other surprising features too. In fact, their wings kill bacteria on contact and are self-cleaning. Researchers using the Department of Energy’s (DOE) Oak Ridge National Laboratory and Brookhaven National Laboratory user facilities investigated this bizarre phenomenon. They learned how structures in the cells are able to pull off such a feat and how it could be used in medical applications.
Paul F. Pasquina Named The Geneva Foundation Researcher of the Year
Uniformed Services University of the Health Sciences (USU) Department of Physical Medicine and Rehabilitation professor and chair Dr. Paul F. Pasquina has been named Researcher of the Year by The Geneva Foundation.
First-generation medical students face unique challenges and need more targeted support
A study published in JAMA confirms that first-gen medical students feel that they face disproportionate adversity throughout their education and do not receive the support they need to compensate for that.
Prebys Foundation Announces $7 Million “Prebys Research Heroes” Program to Improve Medical Research through Diversity
The Prebys Foundation has launched a $7 million program designed to bring more diverse perspectives into the laboratory and yield ground-breaking medical research.
LJI home to new “Center of Excellence”
The Institute’s Flow Cytometry Core, which provides cutting-edge research services, has been named a BD Biosciences “Center of Excellence.” Along with this distinction, the LJI Flow Core has brought in a sophisticated instrument for immune cell research: the BD FACSDiscover™ S8 Cell Sorter.
Shuffling the deck for privacy
By integrating an ensemble of privacy-preserving algorithms, a KAUST research team has developed a machine-learning approach that addresses a significant challenge in medical research: How to use the power of artificial intelligence (AI) to accelerate discovery from genomic data while protecting the privacy of individuals
Boosting weak immune system: scientists find an unusual weapon against virus
New approach boosts immune system to fight CMV in immunocompromised mice.
House appropriations bill would slash life-saving medical research, disease prevention and treatment
The Endocrine Society opposes severe funding cuts proposed in the House Labor, Health and Human Services, Education, and Related Agencies (Labor-HHS) funding bill that would put life-saving endocrine research, disease prevention, and treatment at risk.
CIHR chooses Digital Science to support discoveries for Canada’s health
Digital Science is pleased to announce that the Canadian Institutes of Health Research (CIHR) has chosen Altmetric and Dimensions from Digital Science’s flagship products to support its belief that research has the power to change lives.
The 2023 American Association of Neurological Surgeons Annual Scientific Meeting Features Never-Before-Presented Research
The American Association of Neurological Surgeons (AANS) Annual Meeting will be the first ever to showcase the late-breaking abstract “Decompressive Craniectomy vs Craniotomy for Traumatic Acute Subdural Hematoma” Sunday, April 23, at 9:10 am-9:18 am, during Plenary Session ll.
Study: Spice May Improve Ovarian Cancer Treatment
New research makes the case for why curcumin could help enhance treatment for ovarian cancer.
Hackensack Meridian JFK Johnson Rehabilitation Institute Physicians, Researchers To Present At The Association of Academic Physiatrists National Conference
“We welcome the opportunity to present the important research we’re doing at JFK Johnson to a national audience,” said Sara Cuccurullo, chair, vice president and medical director of JFK Johnson Rehabilitation Institute. “Our goal is to improve outcomes for our patients and also to advance the specialty of rehabilitation medicine to help patients everywhere.”
Female and male hearts respond differently to stress hormone
Female and male hearts respond differently to “fight or flight” stress hormone, according to a new UC Davis study in mice. It may help explain sex differences in arrhythmia risk.
UAlbany Start-Up Receives Federal Support to Develop New Technology for Early Diagnosis of Alzheimer’s Disease
Early Alzheimer’s Diagnostics LLC was awarded a highly competitive NSF Small Business Technology Transfer grant. It will be used to advance the commercialization of a screening tool that tests saliva for the detection of early and preclinical Alzheimer’s disease.
UT Southwestern scientists among top 1% of highly cited researchers across the globe
More than 20 UT Southwestern Medical Center scientists are among the 2022 Highly Cited Researchers listed in the top 1% of researchers from across the globe
Cleveland Clinic and IBM Begin Installation of IBM Quantum System One
Cleveland Clinic and IBM have begun deployment of the first private sector onsite, IBM-managed quantum computer in the United States. The IBM Quantum System is to be located on Cleveland Clinic’s main campus in Cleveland.
The first quantum computer in healthcare, anticipated to be completed in early 2023, is a key part of the two organizations’10-year partnership aimed at fundamentally advancing the pace of biomedical research through high-performance computing. Announced in 2021, the Cleveland Clinic-IBM Discovery Accelerator is a joint center that leverages Cleveland Clinic’s medical expertise with the technology expertise of IBM, including its leadership in quantum computing.
New Study in Journal of Head Trauma Rehabilitation Explores Predictors of High School and College Graduation for Young People with Traumatic Brain Injury
“A broad range of efforts across society are needed to understand and combat racial inequity in the school systems to better support students with traumatic brain injury who come from ethnic and racial minority groups,” said Ashley Kakkanatt, MD, physical medicine and rehabilitation at Hackensack Meridian JFK Johnson Rehabilitation Institute and a coauthor of the study who worked on it during her fellowship training there. She now serves as an attending physician at JFK Johnson.
AOSSM Journals Receive Highest Impact Factors in Organization’s History
Scientific journal Impact Factors were just released this week by Clarivate and all three AOSSM Medical Publishing Group (MPG) journals achieved their highest rankings in the organization’s publication history. The Impact Factor (IF) is a measure of the frequency with which the average article in a journal has been cited in a particular year. It is used to measure the importance or rank of a journal by calculating the times its articles are cited.
University Hospitals and UC Irvine Announce New Co-Leadership of BraveNet, a Practice-Based Integrative Medicine Research Network
University Hospitals (UH) Connor Whole Health and Susan Samueli Integrative Health Institute (SSIHI) at University of California, Irvine have joined in collaboration to lead BraveNet — the first and largest whole health, practice-based research network in the U.S.
Hero’s Encounter: Leading Geriatrician and World War II Veteran Share Bond
An internationally renowned geriatrician and advocate for seniors and a 98-year-old World War II veteran hero are a dynamic duo whose paths recently crossed. They have a common bond: to improve care and quality of life for Americans and people throughout the world.
SHRO’s Giordano Meets with Appropriations Committee Chair on Capitol Hill
Professor Antonio Giordano, M.D., Ph.D., Neopolitan Oncologist, Director of the Sbarro Institute for Cancer Research at Temple University and founder of the Sbarro Health Research Organization (SHRO), met today with Congresswoman Rosa DeLauro (D-CT), Chair of the House Appropriations Committee, at the Rayburn House Office Building on Capitol Hill.
National Italian American Foundation Awards Fauci Scholarships at Annual Gala
NIAF Board Member and SHRO Director Antonio Giordano leads scholarship committee.
Study may show why MS patients develop progressive disability but those with related diseases do not
Did you know multiple sclerosis (MS) means multiple scars? New research shows that the brain and spinal cord scars in people with MS may offer clues to why they developprogressive disability but those with related diseases where the immune system attacks the central nervous system do not.
In a study published in Neurology, Mayo Clinic researchers and colleagues assessed if inflammation leads to permanent scarring in these three diseases:
Southwest National Primate Research Center at Texas Biomed receives $37 million NIH grant
The Southwest National Primate Research Center (SNPRC) at Texas Biomed has been awarded more than $37 million from the National Institutes of Health to continue operations into 2026. The P51 grant, given by the NIH Office of Research Infrastructure Programs, provides essential funding to house and care for nearly 2,500 non-human primates that are part of life-science research programs at Texas Biomed and partners around the globe.
Improved method for generating synthetic data solves major privacy issues in research
Researchers at the Finnish Center for Artificial Intelligence have developed a machine learning-based method that produces synthetic data, making it possible for researchers to share even sensitive data with one other without privacy concerns.
2021 Award Winners Announced at 30th AMSSM Annual Meeting
The American Medical Society for Sports Medicine presented the following awards during its 30th Annual Meeting on April 17, 2021.
Brain sensor offers Alzheimer’s answers
Scientists have found an explanation for why Alzheimer’s drugs have limited effectiveness and why patients get much worse after going off of them.
Diversity Among Study Participants Credited with Identifying Gene Linked to Asthma
Researchers at Henry Ford Health System, as part of a national asthma collaborative, have identified a gene variant associated with childhood asthma that underscores the importance of including diverse patient populations in research studies.
The study is published in the print version of the American Journal of Respiratory and Critical Care Medicine.
World-Renowned Interventional Cardiologist Establishes Structural Heart Disease Research Fund in Honor of Late Wife
William O’Neill, M.D., director of the Center for Structural Heart Disease at Henry Ford Health System, has donated $1 million to establish the Carol S. O’Neill Structural Heart Disease Research Fund at Henry Ford Health System in honor of his late wife, Carol, who passed away in 2019.
Case Western Reserve University and University Hospitals Announce 10-Year Affiliation Extension
Announcement of an extended affiliation agreement between Case Western Reserve University and University Hospitals. The affiliation, through 2031, is an amendment that expands opportunities for collaboration between the two organizations.
“This is how we can help” – Couple shares their story as COVID-19 clinical trial participants
“I don’t feel so great,” my husband, Brandon, said to me one Saturday afternoon – the last thing I wanted to hear after spending the last seven months tuned into COVID-19 media coverage. Knowing a few of his co-workers had recently tested positive for the virus, we didn’t wait to secure an appointment for a rapid test. When he called me an hour later to tell me he has tested positive, my heart sank.
Ultrasound Technique Offers More Precise, Quantified Assessments of Lung Health
Researchers have developed a technique that uses ultrasound to provide non-invasive assessments of pulmonary fibrosis and pulmonary edema. The technique has been shown to both quantify lung scarring and detect lung fluid in rats. A study on pulmonary edema in humans is under way.
Harrington Discovery Institute Announces Award Recipients in New UK Rare Disease Program
Announcement of the 2021 Harrington UK Rare Disease Scholar Award recipients, their organizations and fields of research:
Pietro Fratta, MD, PhD – University College London
Gene Therapy for Kennedy’s Disease, a rare neuromuscular disease
Angela Russell, DPhil – University of Oxford
New Drugs for the Treatment of Duchenne Muscular Dystrophy
Helen Waller-Evans, DPhil – Cardiff University
Novel Inhibitors to Treat Multiple Lysomal Storage Disorders, causes of widespread organ damage
Wyatt Yue, PhD – University of Oxford
Inhibitors of Primary Hyperoxaluria, a cause of kidney failure
Haiyan Zhou, MD, PhD – University College London
Novel Therapy for SPTLC1-Related Hereditary Sensory Neuropathy, a cause of shooting pain
Ohio State Study Shows Cardiac MRI Effective in Identifying Myocarditis in Athletes
A cardiac MRI is effective in identifying inflammation of the heart muscle in athletes and can help determine when those who have recovered from COVID-19 can safely return to play in competitive sports, according to a new study by researchers at The Ohio State University Wexner Medical Center.
UChicago Medicine joins BOOST-3 national trial to investigate treatments for traumatic brain injuries
As part of nationwide study to improve trauma care for severe brain injuries, researchers at UChicago Medicine are working to engage South Side residents and ensure representation among underrepresented communities.
Clinical trials for potential COVID-19 vaccines need to include a more diverse roster of participants
Those who lead clinical trials for potential COVID-19 vaccines need to include more minorities. According to Marjorie A. Speers, executive director of non-profit Clinical Research Pathways and a former CDC official, Black and Latino patients are vastly under-represented in most…
The Eye, The Brain & The Auto: Call for Research Abstracts from Healthcare and Automotive Experts
The Detroit Institute of Ophthalmology, the research arm of the Henry Ford Health System Department of Ophthalmology, is accepting abstracts for The Eye, The Brain & The Auto 9th World Research Congress on Health and Modern Mobility: Autonomous Vehicles, Driver’s Fitness to Function, and Naturalistic Driving Methods to be held Dec. 7-8, 2020. This will be a virtual event.
Focused ultrasound shows promise against deadliest brain tumor
An innovative use of focused ultrasound is showing promise against glioblastoma, the deadliest brain tumor, and could prove useful against other difficult-to-treat cancers.
Essential key to hearing sensitivity discovered in inner ear
New research is shedding light on the biological architecture that lets us hear – and on a genetic disorder that causes both deafness and blindness.
The critical role clinical research professionals can play in FDA’s #expandedaccess program.
The Association for Clinical Research Professionals (ACRP) published in their May journal an essay written by Clinical Research Pathways Executive Director Marjorie A. Speers, Ph.D. In her piece, Speers discusses the critical role clinical research professionals play in the FDA’s…
Coronavirus knowledge needs to be shared freely, not kept secret by governments, corporations
Government agencies and medical institutions have been hit hard recently by hackers attempting to steal coronavirus research. The US and other countries are battling to keep their coronavirus innovations secret (or protect their research in other ways) partly because they…
Spinal cord injuries: Scientists probe individual cells to find better treatments
Two top scientists are seeking answers to questions about spinal cord injuries that have long frustrated the development of effective treatments.
Soup to Nuts
The COVID-19 pandemic demands action on many fronts, from prevention to testing to treatment. Not content to focus its research efforts on just one, the laboratory of George Church in the Blavatnik Institute at Harvard Medical School and the Wyss Institute for Biologically Inspired Engineering at Harvard University is tackling the problem from seven different angles.
Epidemiology expert: Strive for diversity in COVID-19 vaccine/drug clinical trials
As clinical trials on potential vaccines and treatment drugs for the COVID-19 disease caused by the novel coronavirus get underway, researchers should strive for diversity in test subject selection, according to a leading expert on the topic. Marjorie A. Speers,…
Genetics Researchers Find Easy Way to Improve Cancer Outcomes
By mining a vast trove of genetic data,researchers at the University of Virginia School of Medicine are enhancing doctors’ ability to treat cancer, predict patient outcomes and determine which treatments will work best for individual patients. The researchers have identified inherited variations in our genes that affect how well a patient will do after diagnosis and during treatment.
Understanding How COVID-19 Affects Children Vital to Slowing Pandemic, Doctors Say
Though COVID-19 so far appears to be largely sparing children, researchers are cautioning that it is critical to understand how the virus affects kids to model the pandemic accurately, limit the disease’s spread and ensure the youngest patients get the care they need.
Discovered: Why obesity causes high blood pressure — and potential ways to fix it
The researchers have already confirmed their discovery in human tissue samples and used it to reverse high blood pressure in lab mice.
Harrington Discovery Institute at University Hospitals Opens Call for 2021 Harrington Scholar-Innovator Award
An announcement that the Harrington Discovery Institute at University Hospitals is accepting letters of intent for the 2021 Harrington Scholar-Innovator Award. The award offers inventive physician-scientists resources and expertise to advance their discoveries into medicines.
The potentially deadly paradox of diabetes management
Diabetes affects nearly 1 in 10 adults in the U.S., of these millions, more than 90% have Type 2 diabetes. Controlling blood sugar and glycosylated hemoglobin levels ― or HbA1c, which is sometimes referred to as A1C ― is key to diabetes management and necessary to prevent its immediate and long-term complications. However, new Mayo Clinic research shows that diabetes management may be dangerously misaligned.