Study Sheds Light on Mechanism of Liposome Accumulation in Tumors

Dmitri Simberg, PhD, associate professor in the University of Colorado Skaggs School of Pharmacy, released a new study of the effectiveness of different types of fluorescent labels used to monitor the accumulation of liposomes in tumors. The study was published on July 1, 2021, in ACS Nano.

New immunotherapy target discovered for malignant brain tumors

Scientists say they have discovered a potential new target for immunotherapy of malignant brain tumors, which so far have resisted the ground-breaking cancer treatment based on harnessing the body’s immune system. The discovery, reported in the journal CELL, emerged from laboratory experiments and has no immediate implications for treating patients.

Ingo Mellinghoff Named Chair of MSK’s Department of Neurology

Neuro-oncologist and renowned physician-scientist Ingo Mellinghoff will lead MSK’s distinguished Department of Neurology after previously serving as Acting Co-Chair.

Rutgers Cancer Institute Researchers Utilize 4D Printing with Patient Derived Organoids to Accelerate Treatment Testing for Common Brain Tumor

Rutgers Cancer Institute investigator shares about a new project in which 4-dimensional (4D) printing of arrays that transform from cell-culture inserts into histological cassettes are utilized and hold patient tissue samples for rapid programmable drug testing to accelerate treatment testing for glioblastoma multiforme (GBM), a common brain tumor.

Brain Cancer: UVA IDs Gene Responsible for Deadly Glioblastoma

The discovery of the oncogene responsible for glioblastoma could be the brain tumor’s Achilles’ heel, one researcher says.

Bridging the gap between AI and the clinic Rapprocher l’IA de la pratique clinique

Researchers trained machine learning algorithms on data from more than 62,000 patients with a meningioma. Their goal was to find statistical associations between malignancy, survival, and a series of basic clinical variables including tumour size, tumour location, and surgical procedure.

Des chercheurs ont entraîné des algorithmes d’apprentissage automatique à partir des données de plus de 62 000 patients ayant un méningiome. L’objectif était de déceler des associations statistiques entre la malignité, le temps de survie et d’autres variables cliniques de base telles que la taille de la tumeur, son emplacement et la nature de l’intervention chirurgicale effectuée.

Zika Virus’ Key into Brain Cells ID’d, Leveraged to Block Infection and Kill Cancer Cells

Two different UC San Diego research teams identified the same molecule — αvβ5 integrin — as Zika virus’ key to brain cell entry. They found ways to take advantage of the integrin to both block Zika virus from infecting cells and turn it into something good: a way to shrink brain cancer stem cells.

First Molecular Test in US to Better Detect Brain Tumors Now Available to Patients

NYU Langone Health and its Perlmutter Cancer Center have launched clinical whole genome DNA methylation profiling for patients with brain tumors.
This leading-edge molecular assay utilizes DNA epigenetic signatures and artificial intelligence with machine learning to correctly identify and subtype brain tumors. NYU Langone Health is the first Clinical Laboratory Improvement Amendments (CLIA)-certified laboratory in the United States to receive state approval (New York State Department of Health) for whole genome DNA methylation for diagnosis and classification of brain tumors.

Sibling Bond Gets Brother with Large Brain Tumor the Best Care

When Gary Colon, 51, of Miami, Florida suddenly had trouble speaking, he called his sister, Becky, of Stratford, Connecticut for help. She urged him to go to an emergency department, where he had tests that revealed a meningioma. This large brain tumor was indenting and injuring the speech area of his brain.

Becky quickly made arrangements for Gary to come home and have brain surgery at Norwalk Hospital, where she’s worked for 17 years and knew he would get the best care.

Norwalk Hospital is equipped to handle these types of brain surgery cases because of the highly trained neurosurgeons, and seasoned physician assistants, nurses, medical assistants, operating room staff, and intensive care unit staff who work so well together.

CNS Gift to the CNS Foundation Doubles Innovative Clinical Research Initiative, Creating Annual NINDS/CNSF K12 Scholar Awards

The Congress of Neurological Surgeons Foundation (CNS Foundation) announced a second K12 award will be funded by a generous gift from the Congress of Neurological Surgeons (CNS). The award is made possible through a collaboration with the Foundation of the National Institutes of Health (FNIH) and the National Institutes of Health (NIH).