St. Jude Children’s Research Hospital study highlights the power of comprehensive whole genome, whole exome and RNA sequencing to better understand and treat each patient’s cancer.
Neuroblastoma is the deadliest and most common solid cancer in young children the world over, accounting for 15 per cent of all childhood cancer deaths. But Australian researchers are taking the first steps to find the cause and better treatments for this devastating disease which affects children under the age of five.
The risk of childhood leukemia among kids with Down syndrome is higher than predicted, according to a new study led by UC Davis and UC San Francisco researchers. Early diagnosis remains critical.
Children and young adults who receive CAR T-cell therapy for the most common childhood cancer – acute lymphoblastic leukemia – suffer remarkably fewer relapses and are far more likely to survive when the treatment is paired with a subsequent stem cell transplant, a new study finds.
Scientists at St. Jude Children’s Research Hospital are learning more about what the molecular groups of a rare pediatric brain tumor mean for clinical care.
A new study by Mayo Clinic researchers has identified that a chromosome instability gene, USP24, is frequently missing in pediatric patients with neuroblastoma, an aggressive form of childhood cancer. The finding provides important insight into the development of this disease. The study is published in Cancer Research, the journal of the American Association for Cancer Research.
Scientists at St. Jude Children’s Research Hospital have identified genetic variants in African American childhood cancer survivors that have implications for up-front care and long-term surveillance.
Sara Federico, MD, received the NCI award for substantial impact in the field of childhood solid tumors through the development and conduct of clinical trials
The National Comprehensive Cancer Network announces publication of new NCCN Guidelines for Pediatric Hodgkin Lymphoma, one of the most curable forms of pediatric cancer. They synthesize the latest evidence and expert-consensus to make sure every child receives appropriate, but not excessive, treatment.
NCCN publishes a new patient and caregiver resource focused on a childhood cancer type. Free NCCN Guidelines for Patients: Pediatric Acute Lymphoblastic Leukemia (ALL) shares the latest expert advice for treating infants, children, and adolescents with the most common pediatric malignancy.
Family looks to the ‘bright side’ by creating a charity to support pediatric cancer research and providing UChicago Medicine Comer Children’s Hospital with $500,000 gift.
In mouse models of DIPG, simultaneously attacking two metabolic pathways led to significant improvements in survival.
Scientists at St. Jude Children’s Research Hospital are studying how hearing loss can affect the neurocognitive abilities of childhood cancer survivors. Findings show that survivors with severe hearing loss are at a significant increased risk for neurocognitive deficits, independent of what type of therapy they receive.
Stacey Crane, PhD, RN, will use a new grant from the St. Baldrick’s Foundation to pilot test a web-based interface designed to make it easier for kids with cancer and their parents to report symptoms in real time with the ultimate goal of improving kids’ outcomes. Crane is an assistant professor in the Department of Research at Cizik School of Nursing at The University of Texas Health Science Center at Houston (UTHealth).
Scientists at Sanford Burnham Prebys have discovered that combining immunotherapy with a drug called tumor necrosis factor (TNF) eradicated a deadly type of pediatric brain tumor in mice. The discovery, published in Nature Neuroscience, is expected to lead to a clinical trial to test the benefits of the treatment in patients. The findings also hold implications for other cancers that do not respond to immunotherapy.
St. Jude Children’s Research Hospital, in partnership with the International Society of Paediatric Oncology (SIOP), today launched the Global COVID-19 Observatory and Resource Center for Childhood Cancer.
Racial and ethnic minority children and adolescents with cancer have a higher risk of death than non-Hispanic white children and adolescents, with evidence for larger disparities in survival for more treatable cancers, finds a new study from the Brown School at Washington University in St. Louis.“The results suggest that there are modifiable racial and ethnic disparities in childhood cancer survival,” said Kim Johnson, associate professor and senior author of “Associations Between Race/Ethnicity and US Childhood and Adolescent Cancer Survival by Treatment Amenability,” published Feb.
The Together website by St. Jude offers information about diseases, diagnosis and treatment options, as well as supportive care resources and shared stories of hope, healing and experience.
Along with a healthy lifestyle, regular screening can help with the prevention of cancer. Rutgers Cancer Institute of New Jersey experts share additional information during this Cancer Prevention Month.
Mount Sinai researchers have identified a targeted therapy for adolescent patients with neuroblastoma, a deadly pediatric nerve cancer, who would otherwise have no treatment options, according to a study published in October in Cancer Cell.
Roswell Park’s Dr. Clare Twist led an effort to develop and validate a new treatment algorithm for infants and children with neuroblastoma. In a new study in the Journal of Clinical Oncology, the team reports that many patients can safely receive less extensive therapy.