Study Finds Neglected Mutations May Play Important Role in Autism Spectrum Disorder

Mutations that occur in certain DNA regions, called tandem repeats, may play a significant role in autism spectrum disorders, according to research led by Melissa Gymrek, assistant professor in the UC San Diego Department of Computer Science and Engineering and School of Medicine. The study, which was published in Nature on Jan. 14, was co-authored by UCLA professor of human genetics Kirk Lohmueller and highlights the contributions these understudied mutations can make to disease.

Read more

Making sense of a universe of corn genetics

A new study details the latest efforts to predict traits in corn based on genomics and data analytics. The data management technique could help to “turbo charge” the seemingly endless amount of genetic stocks contained in the world’s seed banks, leading to faster and more efficient development of new crop varieties.

Read more

Genetic Code Evolution and Darwin’s Evolution Theory Should Consider DNA an ‘Energy Code’

Darwin’s theory of evolution should be expanded to include consideration of a DNA stability “energy code” – so-called “molecular Darwinism” – to further account for the long-term survival of species’ characteristics on Earth, according to Rutgers scientists. The iconic genetic code can be viewed as an “energy code” that evolved by following the laws of thermodynamics (flow of energy), causing its evolution to culminate in a nearly singular code for all living species, according to the Rutgers co-authored study in the journal Quarterly Review of Biophysics.

Read more

How Did Red Algae Survive in Extreme Environments?

Red algae have persisted in hot springs and surrounding rocks for about 1 billion years. Now, a Rutgers-led team will investigate why these single-celled extremists have thrived in harsh environments – research that could benefit environmental cleanups and the production of biofuels and other products.

Read more

Research into SARS-CoV-2 mutation “hotspots” raises implications for vaccines and therapeutics

Researchers have found at least 10 distinct “hotspot” mutations in more than 80% of randomly selected SAR-CoV-2 sequences from six countries, and these genome hotspots – seen as “typos” that can occur as the virus replicates during cellular division – could have a significant impact in the fight against the COVID-19 pandemic.

Read more

One-size-fits-all is no fit for heart health

From Weight Watchers to wearable tech – wherever we look, there are messages encouraging us to stay fit and healthy. But diets and training methods aside, when it comes to heart health, research from the University of South Australia shows that a far more personalised approach is needed…and it all starts with your genes.

Read more