Researchers Use Model of Hypothalamus to Implicate Genes Associated with Sleep, BMI, Puberty, and More

A new study has implicated several genes involved in a variety of bodily functions associated with the hypothalamus, a notoriously difficult-to-study region of the brain. The findings could help clinicians identify potential causes of dysfunction for many important traits regulated by the hypothalamus, such as sleep, stress, and reproduction.

Blood test for depression, bipolar disorder offers promise of personalized treatment

Worldwide, 1 in 4 people will suffer from a depressive episode in their lifetime.
While current diagnosis and treatment approaches are largely trial and error, a breakthrough study by Indiana University School of Medicine researchers sheds new light on the biological basis of mood disorders and offers a promising blood test aimed at a precision-medicine approach to treatment.

Disrupted biochemical pathway in the brain linked to bipolar disorder

In new research, scientists at the University of Wisconsin–Madison have found for the first time that disruptions to a particular protein called Akt can lead to the brain changes characteristic of bipolar disorder. The results offer a foundation for research into treating the often-overlooked cognitive impairments of bipolar disorder, such as memory loss, and add to a growing understanding of how the biochemistry of the brain affects health and disease.

ALCEDIAG to announce game changing solutions in mental health diseases & diagnostic tools based on RNA-editing blood biomarkers

ALCEDIAG, one of 3 finalists for the “Disruptive Technology Award” at the annual AACC meeting 2020, will be holding a press conference to announce a game-changing technology and diagnostic tool for precision medicine in psychiatry: EDIT-BTM, the very first blood test for a high-performance differential diagnosis of unipolar depression and bipolar disorder.

Therapy plus medication better than medication alone in bipolar disorder

A review of 39 randomized clinical trials by scientists from UCLA and their colleagues from other institutions has found that combining the use medication with psychoeducational therapy is more effective at preventing a recurrence of illness in people with bipolar disorder than medication alone.

Unexpected Mental Illnesses Found in a Spectrum of a Rare Genetic Disorder

UC Davis MIND Institute researchers found an unexpected spectrum of mental illnesses in patients with a rare gene mutation. These patients had a “double hit” condition that combined features and symptoms of fragile X syndrome and premutation disorder, in addition to a range of psychiatric symptoms. The findings revealed the need for clinicians to consider the complexities of the co-existing conditions of patients with both psychological and fragile X associated disorders.