Biomarker | sciencenewsnet.in

Researchers make significant step toward blood test for Alzheimer’s disease

July 28, 2020 sarah Jonas Alzheimer's Disease, Biomarker, Blood Test, Dementia, Neurodegenative Disease, Neurodegeneration, tau

Researchers at Washington University School of Medicine in St. Louis have developed a technique to detect minute amounts of a protein fragment linked to Alzheimer’s disease in the blood. The study, which will be published July 28 in the Journal of Experimental Medicine (JEM), shows that levels of p-tau-217 are elevated during the early stages of Alzheimer’s disease and could lead to a simple blood test capable of diagnosing the neurodegenerative disorder years before any symptoms begin to appear.

Research Results

Cancer Researchers Have a Head Start in Fight Against COVID-19

June 9, 2020 sarah Jonas Biomarker, Convalescent Plasma, Coronavirus, covid 19, Immunotherapy, Inflammation, sarilumab, SARS-CoV-2

Researchers at Roswell Park Comprehensive Cancer Center have been actively engaged in the effort to develop treatments or other control strategies that can help communities worldwide to address the impacts of the COVID-19 pandemic.

Research Results

Biomarkers May Help Us Understand Recovery Time After Concussion

May 27, 2020 sarah Jonas Biomarker, Concussion, Neurology, traumatic brain injury (TBI)

A blood test may help researchers understand which people may take years to recover from concussion, according to a study published in the May 27, 2020 online issue of Neurology®, the medical journal of the American Academy of Neurology. The study looked at a biomarker called neurofilament light chain, a nerve protein that can be detected in the blood when nerve cells are injured or die.

Research Results

Combining Multiple Measures of Alcohol Use Helps Clarify Risky Drinking in People with HIV

May 22, 2020 sarah Jonas Alcohol Use Disorder, Biomarker, heavy drinking

Researchers and clinicians can better understand the health risks facing people with HIV through comprehensive measures of alcohol use, including objective biomarkers, according to a new study in Alcoholism: Clinical and Experimental Research. Frequent or heavy alcohol use in people with HIV can affect HIV disease progression and comorbidities. Alcohol use disorder is a barrier to effectively managing HIV and contributes in multiple ways to poor health outcomes. These effects are not well understood, however, owing in part to the limitations of self-report tools (questionnaires) for measuring alcohol use. Researchers at Louisiana State University and Tulane University correlated self-reported alcohol use, measured by multiple questionnaires, with a biomarker of alcohol consumption in people with HIV. This study explores the implications of this multi-faceted approach for understanding the alcohol use of people with HIV and the related risk factors.

Research Results

Researchers Discover Biomarkers of ALS in Teeth

May 21, 2020 sarah Jonas ALS, Biomarker, ENVIRONMENTAL HEALTH, exposomics, Neurology

Mount Sinai scientists have identified biological markers present in childhood that relate to the degenerative and often fatal neurological disease called amyotrophic lateral sclerosis, also known as ALS or Lou Gehrig’s disease, according to a study published in the Annals of Clinical and Translational Neurology in May.

Announcement

Roswell Park’s Dr. Pawel Kalinski to Lead $14.5M NCI-Funded Immunotherapy Effort

March 31, 2020 sarah Jonas Biomarker, checkpoint inhibitor, immunotheraphy, NCI, Tumor

A team led by Pawel Kalinski, MD, PhD, of Roswell Park Comprehensive Cancer Center has earned a five-year, $14.54 million award from the National Cancer Institute (NCI) to expand a promising immunotherapy platform. Funded through the NCI’s Program Project Grant program, this prestigious five-year grant will fund five clinical trials, all focused on a strategy for making some of the most common immunotherapies work for more cancer patients.

Research Results

Discovery of new biomarker in blood could lead to early test for Alzheimer’s disease

March 31, 2020 sarah Jonas Alzheimer's Disease, Bioengineering, Biomarker, biomarker discovery, Neuroscience

UC San Diego researchers discovered that high blood levels of RNA produced by the PHGDH gene could serve as a biomarker for early detection of Alzheimer’s disease. The work could lead to the development of a blood test to identify individuals who will develop the disease years before they show symptoms.

Research Results

Vinyl Chloride, Nerve Growth Factor, Chemical Warfare, and More Examined in March 2020 Toxicological Sciences

March 5, 2020 sarah Jonas Acute Kidney Injury, Biomarker, Endoplasmic Reticulum, Environmental Exposure, Nerve Growth Factor, Pyrethroid, Pyrethroids, RNA, toxicological sciences, TOXICOLOGY

The March 2020 issue of Toxicological Sciences features leading research in toxicology, covering investigations in biotransformation, toxicokinetics, and pharmacokinetics in addition to work in exposure sciences and environmental toxicology.

Research Results

Blood test identifies risk of disease linked to stroke and dementia

February 3, 2020 sarah Jonas Alzheimer's Disease, Biomarker, Blood Test, Dementia, Neuroscience, Stroke

A UCLA-led study has found that levels of six proteins in the blood can be used to gauge a person’s risk for cerebral small vessel disease, or CSVD, a brain disease that affects an estimated 11 million older adults in the U.S.