news, journals and articles from all over the world.
A recent study has uncovered the molecular mechanisms behind osteocyte death in melanoma bone metastasis, revealing that ferroptosis—an iron-dependent form of cell death—plays a central role in the destruction of bone cells. The research identifies the HIF1α-HMOX1 axis as a critical pathway that induces excessive autophagy and iron overload, leading to osteocyte demise.
Skin Cancer Champions wins a Silver Award from Digital Health Awards Fall 2024 for its contributions to patient education. The community provides accessible, reliable resources for those facing non-melanoma skin cancer.
Key mechanism of resistance to BRAF-targeted melanoma therapy discovered. Potential for developing new cancer therapies with high efficacy by regulating polyamine biosynthesis to suppress resistance.
UCLA’s Dr. Roger Lo was awarded a $2 million grant from the National Institutes of Health to investigate innovative strategies to prevent drug resistance in melanoma treatment and improve the effectiveness of MAPK inhibitors, a common treatment for patients with melanomas that carry the BRAFV600 mutation.
Age-related changes in the fibroblasts, cells that create the skin’s structure, contribute to the development of aggressive, treatment-resistant melanoma in males, according to research in mice by the Johns Hopkins Kimmel Cancer Center.
About 8 to 10 million Americans over age 40 have an overabundance of cloned white blood cells, or lymphocytes, that hamper their immune systems. Although many who have this condition — called monoclonal B-cell lymphocytosis (MBL) — do not experience any symptoms, a new study shows they may have an elevated risk for several health complications, including melanoma, a form of skin cancer.
A new study published today in Cancer Discovery is providing insights into why some Merkel cell carcinoma patients respond to this type of immunotherapy while others do not.
MD Anderson and Summit Therapeutics announced a strategic five-year collaboration to accelerate the development of ivonescimab, a novel PD-1/VEGF bispecific antibody.
After a cold and rainy winter, it’s refreshing to plan summertime outdoor activities or a day at the beach soaking up the sun. But it’s important to remember that too much sun exposure can be harmful.
Jeffrey M. Farma, MD, FACS, of the American College of Surgeons’ Commission on Cancer offers three tips to protect yourself while enjoying time outdoors.
Brian Ingham was only 32 years old when a board-certified dermatologist discovered melanoma on his back during a routine visit to get a tattoo removed in late 2023. The Washington, D.C.-area military pilot said he knew he was at an increased risk as his mother was recently diagnosed with advanced melanoma that same year.
Breakthrough one-time cancer treatment option for select patients with metastatic melanoma and solid tumors now offered at UC San Diego Health.
The American Academy of Dermatology (AAD), in conjunction with the Firefighter Cancer Support Network, will host a free Skin Cancer Check event for an estimated 425 New York City firefighters on Saturday, June 1 at the New York City Firefighter Training Facility on Randall’s Island. The inaugural event kicks off the Academy’s Firefighter Skin Cancer Checks Initiative, a nationwide effort designed to provide free skin cancer checks to 10,000 firefighters by 2026.
ASCO, the largest event in cancer research, is approaching on May 31st. This year’s meeting promises to be particularly groundbreaking, with new findings and innovations that could revolutionize cancer treatment.
Sunburns can be painful and damaging to your skin, while also increasing your risk of skin cancer, the most common cancer in the United States and one of the most preventable. A new survey by the American Academy of Dermatology shows that one in three Americans (36%) got a sunburn in 2023, a significant increase over the previous year.
Skin Brachytherapy, also called radiation seed therapy, offers a non-invasive radiation therapy solution to complement or replace surgery for certain skin cancers. Rajesh V. Iyer, MD, is a radiation oncologist at RWJBarnabas Health and chairman of radiation oncology at Community Medical Center, shares more about this treatment option for patients.
A new survey from the American Academy of Dermatology revealed that Generation Z adults, ages 18-25, are at risk for skin cancer due to increasing rates of tanning and burning. To encourage safe sun habits, the AAD is shining a spotlight on the ways that people can protect themselves from the most common and one of the most preventable types of cancer — skin cancer — this May for Skin Cancer Awareness Month.
A recent American Academy of Dermatology survey of more than 1,000 U.S. adults revealed that outdoor workers — like those who work in construction, landscaping, emergency medical services, and postal delivery — are far more likely to get sunburned and tanned, putting themselves at increased risk for skin cancer, compared to the average American.
While skin cancer is one of the most preventable types of cancer, a recent survey of more than 1,000 U.S. adults found that an increasing number of Americans are reporting sunburn despite knowing how to protect themselves from the sun’s harmful rays.
Even though melanoma is rarer in this population, Black patients are more at risk for getting diagnosed late and having worse survival outcomes. Not all skin cancers are caused by sun exposure, and not all melanomas originate in sun-exposed areas;…
Researchers from The University of Texas MD Anderson Cancer Center presented encouraging findings today from two clinical trials in a plenary session highlighting advances in novel immunotherapy approaches at the American Association for Cancer Research (AACR) Annual Meeting 2024.
U.S. veterans are at a higher risk of developing melanoma, one of the deadliest forms of skin cancer, likely due in part to the occupational hazards associated with active duty in countries near the equator where ultraviolet (UV) levels are higher.
People who have had a kidney transplant are at high risk for developing skin cancers. New research directed by investigators from the Johns Hopkins Kimmel Cancer Center is exploring the best combination of treatments to target skin cancers while preserving the transplanted organs.
Delays in diagnosing melanoma due to Covid-19 lockdowns may have contributed to over 100,000 years of life lost across Europe and over £6bn in costs, mainly indirectly due to loss of productivity, finds a new study led by UCL and University Hospital of Basel researchers.
This special edition features upcoming oral presentations by MD Anderson researchers at the 2023 European Society for Medical Oncology (ESMO) Congress focused on clinical advances across a variety of cancer types.
If you are seeking an expert to discuss diagnosis, treatment and the latest research related to Merkel cell carcinoma, also known as neuroendocrine carcinoma of the skin, Aman Chauhan, M.D., is available. Dr. Chauhan leads the Neuroendocrine Tumor Program at…
On Friday, Jimmy Buffett passed away after fighting Merkel Cell Skin Cancer for four years. Merkel Cell Carcinoma is an aggressive form of skin cancer. While MCC is rare, cancer records indicate that more people are developing this skin cancer than…
Melanoma, the most serious form of skin cancer, is highly treatable when detected early, but when the disease advances, it can lead to death. A new article published in the Journal of the American Academy of Dermatology reveals that men with melanoma — and particularly men with skin of color — are more likely to die than women with melanoma.
UCLA Health dermatologist Caroline Opene, MD treats patients of all skin tones, but as director of the UCLA Health Skin of Color clinic, she has special expertise in treating skin of color.
Healthy human skin is a mosaic of normal and mutation-bearing cells. More cells accumulate more mutations as we age, increasing skin cancer risk. Researchers in the lab of Valentina Greco found injury to the skin promotes healthy-cell expansion, which in…
Skin cancer is the most common cancer in the United States and the fifth-most common worldwide. It only takes one blistering sunburn during childhood or adolescence to nearly double a person’s chance of developing melanoma later in life, according to the American Academy of Dermatology Association.
A new study conducted at Tel Aviv University and the Sheba Medical Center reveals how melanoma cancer cells affect their close environment to support their needs – by forming new lymph vessels in the dermis in order to go deeper into the skin and spread through the body.
In addition to presenting Sylvester Comprehensive Cancer Center research findings, Sylvester experts are available at ASCO to share perspectives on a wide variety of topics and studies ranging from breast cancer to sarcoma, prostate cancer, mesothelioma, melanoma, CNS tumors and more.
A recent American Academy of Dermatology survey of more than 1,000 U.S. adults revealed that many Generation Z adults, ages 18-25, are unaware of the risks associated with overexposure to the sun and believe tanning myths. In recognition of Skin Cancer Awareness Month this May, the AAD encourages everyone to practice safe sun to protect themselves from the sun’s harmful rays and reduce their risks of developing skin cancer.
New biomarkers to improve skin cancer detection and avoid delays in treatment are being developed by researchers at the University of South Australia.
The White House recently announced that during a routine skin cancer screening, a small lesion was found under first lady Jill Biden’s eye. The first lady will undergo Mohs micrographic surgery, also called Mohs surgery, next week to remove the…
Although melanoma is the most serious type of skin cancer, most patients have high chances of surviving the disease. There is evidence that more cases of melanoma are being overdiagnosed in patients who would never experience symptoms.
Free online event for cancer patients and caregivers featuring immunotherapy experts and patient advocates taking place Nov. 11-12, 2022.
Currently, the only FDA approved biomarker for ICI melanoma treatment is the tumor mutation burden assay, but the mechanisms linking it to ICI remain unclear. However, new research out of The Wistar Institute now provides evidence of novel, reliable biomarkers that predict therapy response using advanced computer technology.
The University of Texas MD Anderson Cancer Center’s Research Highlights provides a glimpse into recent basic, translational and clinical cancer research from MD Anderson experts. This special edition features upcoming oral presentations by MD Anderson researchers at the European Society for Medical Oncology (ESMO) Congress 2022 focused on clinical advances across a variety of cancer types. Highlights include promising early data from a novel T cell therapy for solid tumors, targeted therapy progress in rare and advanced cancers, biomarkers of immunotherapy response, and features associated with clinical outcomes in leptomeningeal disease. More information on ESMO content from MD Anderson can be found at MDAnderson.org/ESMO.
A Salon Assistant for 25 years, Barbara Willock not only rescues her clients from bad hair days – she also looks to save their lives. “Many skin cancers go undetected because they are located in places that people might not…
What’s the right amount of sunscreen to use? What’s the right SPF? Should everybody use it? A Penn State Health dermatologist helps you beat the burn in this week’s Medical Minute.
A team of researchers at the University of Michigan Rogel Cancer Center were the first to generate a bona fide mouse model of a Merkel cell carcinoma, a rare and potentially aggressive form of skin cancer. The study outlining these results appeared in the Journal of Clinical Investigation.
Summer is here, and that means more time soaking up the sun for many of us.
Skin cancer is the most common form of cancer. It is estimated that one in five Americans will develop skin cancer in their lifetime. As Skin Cancer Awareness Month continues, it’s important to check your skin regularly, and if you notice a spot on your skin that is different from others or that changes, itches, or bleeds, make an appointment to see a board-certified dermatologist.
New Brunswick, N.J., May 23, 2022– According to the American Cancer Society, skin cancer is the most common type of cancer. While we all want to enjoy the outdoors this summer, increased fun in the sun means an increased risk…
Reminders from a romantic partner might be an effective way to encourage sunscreen use by people age 50 or older, suggests a study in the May/June issue of The Journal of the Dermatology Nurses’ Association, official publication of the Dermatology Nurses’ Association. The journal is published in the Lippincott portfolio by Wolters Kluwer.
Recent studies finding that there is an overdiagnosis of melanoma are a significant cause for concern. However, while many pathologists agree overdiagnosis of skin cancer happens, they don’t change diagnosis behavior.
Sarah Weiss, MD, medical oncologist at Rutgers Cancer Institute of New Jersey and associate professor of medicine at Rutgers Robert Wood Johnson Medical School, answers questions about skin cancer and sun protection that you may be wondering
In a recent survey of more than 1,000 U.S. adults, the American Academy of Dermatology found that while respondents gave themselves high ratings for sun protection and most reported that sun protection is more important to them now than it was five years ago, there’s still a lot they don’t know about how to protect themselves from the sun and the risks of sun exposure, including skin cancer —the most common cancer in the U.S.
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