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UrduA study led by researchers from The University of Texas MD Anderson Cancer Center showed a significant overall survival benefit with ribociclib plus endocrine therapy for postmenopausal patients with hormone receptor-positive (HR+) human epidermal growth factor receptor 2-negative (HER2-) metastatic breast cancer. This is the first demonstration of a survival advantage with a front-line CDK4/6 inhibitor in postmenopausal patients with
HR+/HER 2- advanced breast cancer.
Author: sarah Jonas
ESMO: HER2-targeting antibody-drug improves progression-free survival for women with deadly form of advanced breast cancer
A study led by researchers at the UCLA Jonsson Comprehensive Cancer Center has found that treating women with HER2 positive metastatic breast cancer with the HER2-targeting antibody-drug conjugate trastuzumab deruxtecan (T-DXd) significantly prolongs the length of time the disease is controlled and cancer growth is halted when compared to the current standard of care, trastuzumab emtansine (T-DM1).
International Clinical Trial Delivers Promising Results of HER2-Targeted Therapy for Non-Small Cell Lung Cancer
New data published in the New England Journal of Medicine (NEJM) and featured at the European Society for Medical Oncology (ESMO) Congress 2021 highlights a promising new treatment for individuals with HER2-mutant non-small cell lung cancer (NSCLC).
Antibody-drug conjugate shows impressive activity in patients with non-small cell lung cancer with mutation in HER2 gene
More than half of patients with non-small cell lung cancer (NSCLC) bearing a mutation in the HER2 gene had their tumors stop growing or shrink for an extended time after treatment with a drug that hitches a chemotherapy agent to a highly targeted antibody, an international clinical trial led by investigators at Dana-Farber Cancer Institute has found.
MD Anderson Research Highlights: ESMO 2021 Special Edition
The University of Texas MD Anderson Cancer Center’s Research Highlights provides a glimpse into recent studies in basic, translational and clinical cancer research from MD Anderson experts. This special edition features oral presentations by MD Anderson researchers at the virtual European Society for Medical Oncology (ESMO) Congress 2021 on novel therapeutic approaches, including cell therapy for solid tumors, antibody drug conjugates targeting TROP2 and neoadjuvant pembrolizumab for advanced solid tumors with mismatch repair deficiencies.
Programmable Off-the-Shelf Dendritic Cells as an Immunotherapy Discovery Platform
A new therapeutic era has been ushered in with Adoptive Cell Immunotherapy, which uses patient-harvested T cells genetically engineered against tumor-specific targets.
Now We’re Cooking with Lasers
Imagine having your own digital personal chef; ready to cook whatever you want, tailoring the shape, texture, and flavor just for you–all at the push of a button. Columbia engineers have been working on doing just that, using lasers for cooking and 3D printing technology for assembling foods. In their new study they discovered that laser-cooked meat shrinks 50% less, retains double the moisture content, and shows similar flavor development to conventionally cooked meat.
Leverage Fact Check to Promote Experts: Newswise Live Webinar on Sept. 29th
Join the Newswise editorial team to learn how our Fact Check submission option can help your experts get placements with their commentary about important topics.
Chemical Biologist Eric Wang joins Sanford Burnham Prebys
Eric Wang, Ph.D., has joined Sanford Burnham Prebys as an assistant professor in the Tumor Initiation and Maintenance Program. Wang comes to Sanford Burnham Prebys from the Dana-Farber Cancer Institute, where he was a postdoctoral research fellow.
When organoids meet coronaviruses
Researchers from the group of Hans Clevers in collaboration with the group of Bart Haagmans (Erasmus MC) established an organoid biobank to search for the genes that are essential for the spreading of a SARS-CoV2 infection.
Most Syrian Refugees Yearn to Return Home—but Those Who Want to Migrate West Are Least Likely to Hold Extremist Views
Research shows Syrian refugees were significantly more motivated to return home than to emigrate to the West. Those who were motivated to emigrate were the least likely to endorse extreme religious and political views.
Faculty Receives National Institutes of Health Sexual and Gender Minority Early-Stage Investigator Award
Rutgers School of Public Health assistant professor, Devin English, has received the 2021 Sexual and Gender Minority Early-Stage Investigator Award from the National Institutes of Health.
A new species of otter discovered in Germany
Researchers from the Universities of Tübingen and Zaragoza have discovered a previously unknown species of otter from 11.4-million-year-old strata at the Hammerschmiede fossil site.
COVID-19, who to vaccinate first among workers?
The COVID-19 epidemic, and the lockdowns enforced in many countries, have imposed high costs on the population: a combined health and socio-economic crisis, with the world economy shrank by 4.3 percent in 2020 and 130 million people who will starve due to the global economic crisis.
Chemical discovery gets reluctant seeds to sprout
Seeds that would otherwise lie dormant will spring to life with the aid of a new chemical discovered by a UC Riverside-led team.
How do higher waves cause more ice clouds? Research expedition into arctic sea explains
Some of the most well-known and feared aspects of climate change are its potential effects on weather patterns and how this could accelerate the melting of natural ice.
Rodney Hanners named CEO of Keck Medicine of USC and President and CEO of USC Health System
Rodney Hanners named CEO of Keck Medicine of USC and President and CEO of USC Health System
Texas A&M project to create a more inclusive scientific community
Engaging underrepresented students to create diversity in agriculture and life science fields represents a pressing challenge for the scientific community.
Biden Submarine Deal with Australia a “Crippling Blow” to France, Says Govt. Contracting Expert
The Biden administration announced a deal to help Australia deploy nuclear-powered submarines in an attempt to “reinforce alliances” and send a message to China. France on Thursday reacted with outrage to the announcements that the United States and Britain would help…
NREF and AANS/CNS Tumor Section Announce StacheStrong and NREF Research Grant Recipients
The Neurosurgery Research and Education Foundation (NREF) and the American Association of Neurological Surgeons (AANS) and Congress of Neurological Surgeons (CNS) Section on Tumors are pleased to announce Jacob Young, MD, and Daniel Green Eichberg, MD, as the recipients of the StacheStrong and NREF Research Grants on behalf of the AANS/CNS Section on Tumors. These grants were funded by the NREF through a partnership with StacheStrong, a 501(c)3 not-for-profit charity focused on raising funds and awareness for brain cancer research.
The microbial molecule that turns plants into zombies
A newly discovered manipulation mechanism used by parasitic bacteria to slow down plant aging, may offer new ways to protect disease-threatened food crops.
Coral reefs are 50% less able to provide food, jobs, and climate protection than in 1950s, putting millions at risk
The capacity of coral reefs to provide ecosystem services relied on by millions of people worldwide has declined by half since the 1950s, according to a new University of British Columbia-led study.
Bowen Law School Receives $1 million from Walmart to Fund Court Observation Project
The UA Little Rock William H. Bowen School of Law has received a $1 million grant from Walmart, Inc. The grant will fund a Court Observation Project through Bowen’s new Center for Racial Justice and Criminal Justice Reform. The project will introduce a state-wide court observation initiative that will create and share a transparent body of reliable data and research about Arkansas’s criminal justice system that is otherwise unavailable in the state.
COVID-19 Pandemic Hastens Cleveland Clinic’s Unified Well-Being Strategy
The COVID-19 pandemic has been a catalyst for shaping a new future in healthcare. At the Cleveland Clinic, top priorities throughout the pandemic have been to support caregivers professionally and personally and to help them be their best for themselves, their fellow caregivers, patients, organizations, and communities.
Time until dementia symptoms appear can be estimated via brain scan
Researchers at Washington University School of Medicine in St. Louis have developed an approach to estimating when a person with no cognitive symptoms will start showing signs of Alzheimer’s dementia based on data from brain scans and the person’s age.
Texas A&M AgriLife turns up heat on U.S. hot pepper market
New hot pepper agronomic practices and technologies could help rejuvenate the U.S. market and help reduce production costs for producers.
Common anti-seizure medication associated with elevated fracture risk in kids with epilepsy
A study found that one of the two most commonly prescribed anti-seizure medications is associated with a higher risk of fracture for children and teens with epilepsy. This is significant for this population as it comes during a critical period of bone development, a time during which several features coalesce to develop bone strength that peaks in adulthood.
5 Henry Ford Hospitals Earn Top Quality Recognition for Stroke Care Excellence
All of Henry Ford Health System’s five hospitals that are equipped to treat stroke earned Gold Plus and Honor Roll status for stroke care excellence from the American Heart Association and American Stroke Association.
Cancer Risk After Radioactive Iodine Treatment for Hyperthyroidism
JAMA Network OpenOriginal Investigation Cancer Risk After Radioactive Iodine Treatment for Hyperthyroidism Article PDF JAMA Network OpenInvited Commentary Radioactive Iodine Treatment in Hyperthyroidism and Cancer Mortality—A Still Controversial Issue Article PDF JAMA Network Open EMBARGOED FOR RELEASE: 11 A.M.…
Gut bacteria might be an indicator of colon cancer risk
Researchers are finding a link between the increased presence of certain bacteria in a gut biome and colon cancer.
University of Kentucky Researcher a Force in the Fight Against Lyme Disease
At a time when incidence of Lyme disease is rising across the U.S., a study led by University of Kentucky College of Medicine researcher Brian Stevenson, Ph.D., may provide a significant impact in the fight against the disease. A new study will build upon Stevenson’s three decades of research aimed at understanding Borrelia burgdorferi, the bacteria that causes Lyme disease.
Endocrine Society celebrates UK Court of Appeal decision to preserve access to gender-affirming care
The Endocrine Society applauded the Court of Appeal’s ruling that transgender and gender diverse teenagers are competent to give consent to treatment to delay puberty.
Young People’s Fluctuating Beliefs on Alcohol’s Effects Influence Their Drinking and Consequences
College students’ beliefs around the likelihood and desirability of alcohol’s effects vary over time, and predict drinking level and consequences, according to a study in Alcoholism: Clinical and Experimental Research.
Sex Ed Curriculum Elevates Pregnancy Prevention Skills Among Native American Teens
A sex education program in Arizona significantly impacted key factors associated with pregnancy prevention among Native American teens.
Pelvic Floor Experts Issue New Recommendations for Magnetic Resonance Defecography
The recommendations were developed by the Pelvic Floor Disorders Consortium, a multidisciplinary organization representing the wide range of professionals involved in diagnosis and treatment of pelvic floor disorders. The new recommendations are now available on the DC&R website and appear in the journal’s October issue. Liliana Bordeianou, MD, MPH, of Massachusetts General Hospital Pelvic Floor Disorders Center and Harvard Medical School was senior author of the consensus statement.
First-of-its-kind study: Use of computer-assisted colonoscopies reduces rate of missed lesions
In the first randomized trial examining the role of a deep-learning based computer-aided detection system during colonoscopy in the U.S., researchers reported a relative reduction of the miss rate by nearly a third when computer-aided detection was used in conjunction with standard-of-care colonoscopy.
Chula Marketing Guru Cautioned Entrepreneurs Against “3Ps of Business Taboos” to Survive the Fourth Wave of COVID-19
Chula marketing professor from the Faculty of Commerce and Accountancy warned entrepreneurs of the “3Ps” of things they should not do, and to hang on to their hope. This fourth wave of COVID-19 too shall soon pass.
Long Island Institutions Model the Future of Diverse STEM Education
In pursuit of diversifying the STEM education system, academic and research institutions on Long Island have come together to support emerging STEM professors from underrepresented minority groups. The newly formed collaboration, called the Alliances for Graduate Education and the Professoriate (AGEP) Predominately Undergraduate Institutions (PUI), includes Stony Brook University, Suffolk County Community College, Farmingdale State College, and Brookhaven National Laboratory.
Climate Change Threatens Base of Polar Oceans’ Bountiful Food Webs
A study recently published in Nature Communications suggests that displacing cold-water communities of algae with warm-adapted ones threatens to destabilize the delicate marine food web. The team was led by University of East Anglia researchers and included DOE Joint Genome Institute researchers.
Control of rhabdomyosarcoma cell identity provides clues to possible treatments
Findings from St. Jude Children’s Research Hospital show how control of transcription factors by a common tumor suppressor gene may provide a therapeutic opportunity in a type of childhood cancer.
How to catch a perfect wave: Scientists take a closer look inside the perfect fluid
Scientists have reported new clues to solving a cosmic conundrum: How the quark-gluon plasma – nature’s perfect fluid – evolved into the building blocks of matter during the birth of the early universe.
Study Finds Surprising Early COPD Risks for U.S. Hispanics/Latinos
A new study published online in the Annals of the American Thoracic Society provides the most exhaustive look to date at the risk factors, prevalence and population attributable risk (PAR) of developing chronic obstructive pulmonary disease (COPD) in U.S. Hispanics/Latinos under age 50. PAR estimates the proportion of disease attributable to exposure to disease-causing agents, such as smoking. The researchers used PAR to calculate the burden of early COPD that would be eliminated if the exposure did not take place.
Living laboratory, biodiversity hub: The Oak Ridge National Environmental Research Park
Nestled at the intersection of eastern Tennessee’s Anderson and Roane Counties, the Oak Ridge National Environmental Research Park is a living laboratory and a major resource for conducting ecological studies.
ORNL expertise supports latest IPCC report and efforts to understand, address climate change
Improved data, models and analyses from Oak Ridge National Laboratory scientists and many other researchers in the latest global climate assessment report provide new levels of certainty about what the future holds for the planet and highlight the urgency of decarbonization to avoid the most severe impacts.
Hackensack Meridian Children’s Health Welcomes Pediatric Nephrologist to Lead Pediatric Kidney Transplant Program at Joseph M. Sanzari Children’s Hospital
As head of the transplant program, Dr. Jain will work with the hospital’s more than 30 pediatric subspecialists.
University of Redlands launches human-animal studies major
Have you ever wondered what your dog is thinking or if cows have feelings? Are you interested in the reasons behind the behavior of animals and wish you could learn more about them? University of Redlands’ new major in human-animal studies might be for you.
Argonne teams up with GEVO to apply lab’s GREET Model to company’s net-zero project
Argonne recently teamed up with a Colorado-based biofuel company to perform a critical lifecycle analysis of its Next Gen technology to produce renewable jet fuel from corn grain in what could be a game-changer in biofuel industry.
Rutgers Toxicologist Available to Discuss Dangers of Taking Iodine to Treat COVID-19
Professor Lewis Nelson, M.D., is available to discuss the dangers of gargling, snorting, or ingesting Betadine, an iodine-based antiseptic to treat COVID-19. “Although many topical disinfectants such as povidone-iodine, which, is also known as Betadine, generally destroy viruses on direct…
Yale Cancer Center Study Shows New Drug Combinations Improve Outcomes for Patients with Advanced Lung Cancer
New findings from a large study led by researchers at Yale Cancer Center shows the addition of the drugs oleclumab or monalizumab to durvalumab improved progression-free survival for patients with locally advanced non-small cell lung cancer.
UC: Pilot study of diet/exercise in young adults with intellectual disabilities is promising
Adhering to a diet and exercise program to manage health can be a challenge for anyone.