Combination of dual-targeted therapies and chemotherapy shows high response rates in BRAF-mutated metastatic colorectal cancer

Patients with metastatic colorectal cancer (mCRC) harboring BRAF V600E mutations benefitted from first-line treatment with the targeted therapies encorafenib and cetuximab plus a mFOLFOX6 chemotherapy regimen, according to results from the Phase III BREAKWATER trial led by researchers at The University of Texas MD Anderson Cancer Center.

Blood test could guide use of anti-inflammatory drug celecoxib to reduce risk of colon cancer recurrence

A data analysis from a randomized clinical trial for stage 3 colon cancer patients by investigators at Dana-Farber Brigham Cancer Center found that patients with evidence of residual cancer in their blood after surgery to remove the cancer, may benefit from adding of celecoxib, to post surgery treatment.

National CRNA Week: The House of Representatives Recognizes the Contributions of CRNAs

In honor of National CRNA Week (Jan. 19-25, 2025), U.S. House Representatives Jan Schakowsky (D-IL) Dave Joyce (R-OH) Suzanne Bonamici (D-OR), Brian Fitzpatrick (R-PA), Eleanor Holmes Norton (D-DC) and Paul Tonko (D-NY) again introduced a bipartisan House Resolution on the House floor, “Recognizing the roles and the contributions of America’s Certified Registered Nurse Anesthetists (CRNAs) and their critical role in providing quality healthcare for the public and the nation’s armed forces for more than 150 years and through multiple public health emergencies and beyond.”

University Hospitals Now Offering Ultra-Minimally Invasive Endoscopic Spine Surgery for Patients Experiencing Back Pain

University Hospitals is now offering endoscopic spine surgery for patients needing treatment for back pain due to herniated discs in their spine. Xiaofei (Sophie) Zhou, MD, completed Arthrex’s Endoscopic Spine Training course to bring this advanced procedure to the health system and recently completed the first endoscopic discectomy utilizing Arthrex technology at UH.

New York Valves: The Structural Heart Summit is Back!

The Cardiovascular Research Foundation (CRF) is pleased to announce that registration for the second New York Valves: The Structural Heart Summit is now open. Following the outstanding success of last year’s inaugural conference, New York Valves 2025 is the world’s premier structural heart meeting and continues its mission to shape the future of structural heart care through collaboration, education, and innovation. The summit will take place June 25-27, 2025, at the Jacob K. Javits Convention Center, North in New York City.

AI Predicts COVID-19 Risks, Severity, and Treatment in Hospitalized Patients

Using an AI-driven decision support system to predict the severity of COVID-19 and identify best interventions, researchers analyzed electronic health record data from 5,371 patients admitted to a South Florida hospital. The study specifically aimed to forecast the likelihood of patients requiring admission to an ICU, with or without mechanical ventilation, or an intermediate care unit (IMCU). The goal was to leverage these features to enable faster and more accurate forecasting of treatment plans, potentially preventing critical conditions from worsening.

Long Covid, Italian scientists discovered the molecular ‘fingerprint’ of the condition in children’s blood

A study by the Università Cattolica, Rome campus – Fondazione Policlinico Universitario A. Gemelli IRCCS and the Ospedale Pediatrico Bambino Gesù IRCCS, published in the Nature Group journal ‘Pediatric Research’, identifies the ‘protein signature’ of the condition in plasma, a group of pro-inflammatory molecules present at high concentrations in young patients with the condition.

NUS researchers pioneer DNA-tagged gold nanoparticles for targeted cancer treatment

A team of researchers from NUS has developed a novel method to enhance the precision of cancer treatment using gold nanoparticles tagged with DNA barcodes.Led by Assistant Professor Andy Tay from the Department of Biomedical Engineering in the College of Design and Engineering and Institute of Health Innovation & Technology at NUS, the study demonstrates how gold nanoparticles of specific shapes, such as triangles, excel in delivering therapeutic nucleic acids and heating tumour cells during photothermal therapy.

Development of Next-Generation One-Component Epoxy with High-Temperature Stability and Flame Retardancy

Dr. Jaewoo Kim’s research team at the KIST, has developed a groundbreaking solution to overcome these limitations: the “Epoxy/MXene One-Component Solution.” This innovative material consists of epoxy resin, polymeric imidazole-based latent curing agent particles, and a two-dimensional nanomaterial called MXene.

Scaling up Neuromorphic Computing for More Efficient and Effective AI Everywhere and Anytime

Neuromorphic computing—a field that applies principles of neuroscience to computing systems to mimic the brain’s function and structure—needs to scale up if it is to effectively compete with current computing methods. In a review published Jan. 22 in the journal Nature, 23 researchers, including two from the University of California San Diego, present a detailed roadmap of what needs to happen to reach that goal.

DePaul University experts available to discuss President Trump’s first 100 days

Just days into his second term, President Donald Trump is working quickly to implement his agenda. DePaul University experts are available to discuss key topics surrounding Trump’s first 100 days, including foreign policy, immigration, climate policy and health care.

Why Incarcerated Firefighters Are a Major Part of Wildfire Response

When the fires engulfed Los Angeles and the Pacific Palisades this month, more than 1,000 incarcerated individuals volunteered to battle the fires. Up tp 30 percent of California’s active firefighting workforce can be incarcerated people, making them a considerable factor in the state’s firefighting strategies, according to Alexandra Nur, a criminal justice professor in the UNLV Greenspun College of Urban Affairs.

NYU Tandon research to improve emergency responses in urban areas with support from NVIDIA

A team of researchers from NYU Tandon’s C2SMARTER — a U.S. Department of Transportation-funded Tier 1 University Transportation Center — has received an NVIDIA Academic Grant Program award to develop an advanced simulation system aimed at improving emergency response in urban areas.

Exercise Improves Brain Function, Possibly Reducing Dementia Risk

A study led by scientists at Rutgers University-New Brunswick has shown that specialized cells involved in how the body responds to insulin are activated in the brain after exercise, suggesting that physical activity may directly improve brain function. A recent study, published in Aging Cell, a journal focused on the biology of aging, indicates that therapies targeting this insulin action may be developed to offset or even prevent dementia progression.

Two New Artificial Intelligence Models Seek to Make MRI More Accurate, Reliable

Two new models, developed by researchers in the lab of Li Wang, PhD, associate professor of radiology in the UNC School of Medicine, can produce more accurate and reliable analysis of brain structures, which is critical for early detection, medical diagnosis, and neurological research.

TikTok Ban is Still ‘Fair Game,’ Says Expert on Chinese Business and Government

After TikTok briefly barred U.S. users from its platform on Jan. 19—only to restore access 12 hours later—questions have surfaced about the app’s future. In this Q&A, Victor Shih, director of the School of Global Policy and Strategy’s 21st Century China Center, explores the reasons behind the scrutiny of the app and the potential consequences of a permanent ban.

Cedars-Sinai High-Risk Pregnancy Experts at Society for Maternal-Fetal Medicine Meeting

High-risk pregnancy specialists from Cedars-Sinai will share research and patient care insights during the Society for Maternal and Fetal Medicine (SMFM) Pregnancy Meeting Jan. 27 through Feb. 1 in Denver.

Mood disorders drive feelings of cognitive decline in former college athletes

Former college athletes with a history of concussions were more likely to perceive themselves as cognitively impaired later in life if they had mood disorders such as depression and anxiety – even when testing showed no such decline in mental acuity, a study by UT Southwestern Medical Center researchers has found.

Press registration open for ACS Spring 2025

Press registration is now open for the spring meeting of the American Chemical Society (ACS). ACS Spring 2025 will be held in San Diego, in addition to the ACS Spring 2025 Digital Meeting, on March 23-27. Cutting-edge developments on a range of scientific topics will be featured, and embargoed press releases will be available in advance.