Ribociclib added to endocrine therapy extends survival in postmenopausal patients with metastatic breast cancer

A study led by researchers from The University of Texas MD Anderson Cancer Center showed a significant overall survival benefit with ribociclib plus endocrine therapy for postmenopausal patients with hormone receptor-positive (HR+) human epidermal growth factor receptor 2-negative (HER2-) metastatic breast cancer. This is the first demonstration of a survival advantage with a front-line CDK4/6 inhibitor in postmenopausal patients with
HR+/HER 2- advanced breast cancer.

ESMO: HER2-targeting antibody-drug improves progression-free survival for women with deadly form of advanced breast cancer

A study led by researchers at the UCLA Jonsson Comprehensive Cancer Center has found that treating women with HER2 positive metastatic breast cancer with the HER2-targeting antibody-drug conjugate trastuzumab deruxtecan (T-DXd) significantly prolongs the length of time the disease is controlled and cancer growth is halted when compared to the current standard of care, trastuzumab emtansine (T-DM1).

Antibody-drug conjugate shows impressive activity in patients with non-small cell lung cancer with mutation in HER2 gene

More than half of patients with non-small cell lung cancer (NSCLC) bearing a mutation in the HER2 gene had their tumors stop growing or shrink for an extended time after treatment with a drug that hitches a chemotherapy agent to a highly targeted antibody, an international clinical trial led by investigators at Dana-Farber Cancer Institute has found.

MD Anderson Research Highlights: ESMO 2021 Special Edition

The University of Texas MD Anderson Cancer Center’s Research Highlights provides a glimpse into recent studies in basic, translational and clinical cancer research from MD Anderson experts. This special edition features oral presentations by MD Anderson researchers at the virtual European Society for Medical Oncology (ESMO) Congress 2021 on novel therapeutic approaches, including cell therapy for solid tumors, antibody drug conjugates targeting TROP2 and neoadjuvant pembrolizumab for advanced solid tumors with mismatch repair deficiencies.

Now We’re Cooking with Lasers

Imagine having your own digital personal chef; ready to cook whatever you want, tailoring the shape, texture, and flavor just for you–all at the push of a button. Columbia engineers have been working on doing just that, using lasers for cooking and 3D printing technology for assembling foods. In their new study they discovered that laser-cooked meat shrinks 50% less, retains double the moisture content, and shows similar flavor development to conventionally cooked meat.

NREF and AANS/CNS Tumor Section Announce StacheStrong and NREF Research Grant Recipients

The Neurosurgery Research and Education Foundation (NREF) and the American Association of Neurological Surgeons (AANS) and Congress of Neurological Surgeons (CNS) Section on Tumors are pleased to announce Jacob Young, MD, and Daniel Green Eichberg, MD, as the recipients of the StacheStrong and NREF Research Grants on behalf of the AANS/CNS Section on Tumors. These grants were funded by the NREF through a partnership with StacheStrong, a 501(c)3 not-for-profit charity focused on raising funds and awareness for brain cancer research.

Bowen Law School Receives $1 million from Walmart to Fund Court Observation Project

The UA Little Rock William H. Bowen School of Law has received a $1 million grant from Walmart, Inc. The grant will fund a Court Observation Project through Bowen’s new Center for Racial Justice and Criminal Justice Reform. The project will introduce a state-wide court observation initiative that will create and share a transparent body of reliable data and research about Arkansas’s criminal justice system that is otherwise unavailable in the state.

COVID-19 Pandemic Hastens Cleveland Clinic’s Unified Well-Being Strategy

The COVID-19 pandemic has been a catalyst for shaping a new future in healthcare. At the Cleveland Clinic, top priorities throughout the pandemic have been to support caregivers professionally and personally and to help them be their best for themselves, their fellow caregivers, patients, organizations, and communities.

Common anti-seizure medication associated with elevated fracture risk in kids with epilepsy

A study found that one of the two most commonly prescribed anti-seizure medications is associated with a higher risk of fracture for children and teens with epilepsy. This is significant for this population as it comes during a critical period of bone development, a time during which several features coalesce to develop bone strength that peaks in adulthood.

5 Henry Ford Hospitals Earn Top Quality Recognition for Stroke Care Excellence

All of Henry Ford Health System’s five hospitals that are equipped to treat stroke earned Gold Plus and Honor Roll status for stroke care excellence from the American Heart Association and American Stroke Association.

University of Kentucky Researcher a Force in the Fight Against Lyme Disease

At a time when incidence of Lyme disease is rising across the U.S., a study led by University of Kentucky College of Medicine researcher Brian Stevenson, Ph.D., may provide a significant impact in the fight against the disease. A new study will build upon Stevenson’s three decades of research aimed at understanding Borrelia burgdorferi, the bacteria that causes Lyme disease.

Pelvic Floor Experts Issue New Recommendations for Magnetic Resonance Defecography

The recommendations were developed by the Pelvic Floor Disorders Consortium, a multidisciplinary organization representing the wide range of professionals involved in diagnosis and treatment of pelvic floor disorders. The new recommendations are now available on the DC&R website and appear in the journal’s October issue. Liliana Bordeianou, MD, MPH, of Massachusetts General Hospital Pelvic Floor Disorders Center and Harvard Medical School was senior author of the consensus statement.

Chula Marketing Guru Cautioned Entrepreneurs Against “3Ps of Business Taboos” to Survive the Fourth Wave of COVID-19

Chula marketing professor from the Faculty of Commerce and Accountancy warned entrepreneurs of the “3Ps” of things they should not do, and to hang on to their hope. This fourth wave of COVID-19 too shall soon pass.

Long Island Institutions Model the Future of Diverse STEM Education

In pursuit of diversifying the STEM education system, academic and research institutions on Long Island have come together to support emerging STEM professors from underrepresented minority groups. The newly formed collaboration, called the Alliances for Graduate Education and the Professoriate (AGEP) Predominately Undergraduate Institutions (PUI), includes Stony Brook University, Suffolk County Community College, Farmingdale State College, and Brookhaven National Laboratory.

Climate Change Threatens Base of Polar Oceans’ Bountiful Food Webs

A study recently published in Nature Communications suggests that displacing cold-water communities of algae with warm-adapted ones threatens to destabilize the delicate marine food web. The team was led by University of East Anglia researchers and included DOE Joint Genome Institute researchers.

How to catch a perfect wave: Scientists take a closer look inside the perfect fluid

Scientists have reported new clues to solving a cosmic conundrum: How the quark-gluon plasma – nature’s perfect fluid – evolved into the building blocks of matter during the birth of the early universe.

Study Finds Surprising Early COPD Risks for U.S. Hispanics/Latinos

A new study published online in the Annals of the American Thoracic Society provides the most exhaustive look to date at the risk factors, prevalence and population attributable risk (PAR) of developing chronic obstructive pulmonary disease (COPD) in U.S. Hispanics/Latinos under age 50. PAR estimates the proportion of disease attributable to exposure to disease-causing agents, such as smoking. The researchers used PAR to calculate the burden of early COPD that would be eliminated if the exposure did not take place.

ORNL expertise supports latest IPCC report and efforts to understand, address climate change

Improved data, models and analyses from Oak Ridge National Laboratory scientists and many other researchers in the latest global climate assessment report provide new levels of certainty about what the future holds for the planet and highlight the urgency of decarbonization to avoid the most severe impacts.

Rutgers Toxicologist Available to Discuss Dangers of Taking Iodine to Treat COVID-19

Professor Lewis Nelson, M.D., is available to discuss the dangers of gargling, snorting, or ingesting Betadine, an iodine-based antiseptic to treat COVID-19. “Although many topical disinfectants such as povidone-iodine, which, is also known as Betadine, generally destroy viruses on direct…

Yale Cancer Center Study Shows New Drug Combinations Improve Outcomes for Patients with Advanced Lung Cancer

New findings from a large study led by researchers at Yale Cancer Center shows the addition of the drugs oleclumab or monalizumab to durvalumab improved progression-free survival for patients with locally advanced non-small cell lung cancer.