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New strategy blocks chronic lung disease in mice

February 23, 2021 sarah Jonas Asthma, Chronic Lung Disease, COPD, Cytokine, Exosomes

A new study from Washington University School of Medicine in St. Louis has uncovered a previously unknown role for exosomes in inflammatory respiratory diseases. The study has implications for finding new therapies. Exosomes are tiny compartments released from cells that carry different types of cargo, including inflammatory chemicals called cytokines that can drive lung disease.

Research Results

Scientists ‘Farm’ Natural Killer Cells in Novel Cancer Fighting Approach

January 28, 2021 sarah Jonas Cancer, Exosomes, Natural Killer Cells

Engineers and oncologists teamed to develop a microfluidic chip capable of capturing the body’s natural killer immune cells to harvest their cancer-killing exosomes.

Research Results

Exosome treatment improves recovery from heart attacks in a preclinical study

September 29, 2020 sarah Jonas Cardiology, Exosomes, heart attacks, Heart Failure, human induced pluripotent stem cells, Regenerative Medicine

Research in pigs shows that using the exosomes naturally produced from a mix of heart muscle, endothelial and smooth muscle cells — all derived from human induced pluripotent stem cells — yields regenerative benefits equivalent to the injected human induced pluripotent stem cell-cardiac cells.

Research Results

A new gene therapy strategy, courtesy of Mother Nature

December 16, 2019 sarah Jonas 0 Comments Biomedical Engineering, Exosomes, Gene Therapy, Nanoengineering, Nanoparticles, nanotechnology

Scientists have developed a new gene-therapy technique by transforming human cells into mass producers of tiny nano-sized particles full of genetic material that has the potential to reverse disease processes.