Chronic inflammation caused by obesity may trigger the development of cells that break down bone tissue, including the bone that holds teeth in place, according to new University at Buffalo research that sought to improve understanding of the connection between obesity and gum disease.
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Scientists at the Children’s Medical Center Research Institute at UT Southwestern (CRI) have identified the specialized environment, known as a niche, in the bone marrow where new bone and immune cells are produced. The study, published in Nature, also shows that movement-induced stimulation is required for the maintenance of this niche, as well as the bone and immune-forming cells that it contains. Together, these findings identify a new way that exercise strengthens bones and immune function.
A groundbreaking new type of cancer immunotherapy developed at the Icahn School of Medicine at Mount Sinai trains the innate immune system to help it eliminate tumor cells through the use of nanobiologics, tiny materials bioengineered from natural molecules that are paired with a therapeutic component, according to a study published in Cell in October.
Researchers at The Ohio State University Wexner Medical Center and College of Medicine found that spinal cord injuries in mice cause an acquired bone marrow failure syndrome that may contribute to chronic immune dysfunction.
The CDI team’s findings could ultimately improve cancer treatments for people of advanced age, like that of adult acute myeloid leukemia (AML)
Jada Lucas, a 22-year-old bone marrow recipient from Birmingham, met the bone marrow donor who helped save her life — Jerome Lewis of Philadelphia, Penn. — at donor registry event at Children’s of Alabama.