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UrduNicholas Sama, MD, director of Orthopedic Trauma at HSS Florida, the West Palm Beach location of Hospital for Special Surgery, offers advice to give patients the best chance for proper treatment, healthy healing and a good medical outcome following a bone fracture.
Tag: Osteoporosis
Icahn School of Medicine at Mount Sinai Awarded $21 Million NIH Grant to Advance Understanding of Aging-Related Hormone
Researchers at the Icahn School of Medicine at Mount Sinai have been awarded a $21 million grant from the National Institute on Aging (NIA) of the National Institutes of Health (NIH), to further advance understanding of an aging-related hormone known as follicle-stimulating hormone (FSH), including its potential role in obesity, osteoporosis, and Alzheimer’s disease.
More women report hip fractures earlier in life
Older women with low bone density are more likely to experience their first hip fracture in their 60s compared to older ages, according to research being presented Sunday at ENDO 2024, the Endocrine Society’s annual meeting in Boston, Mass.
Sinomenine increases osteogenesis in mice with ovariectomy-induced bone loss by modulating autophagy
BACKGROUNDA decreased autophagic capacity of bone marrow mesenchymal stromal cells (BMSCs) has been suggested to be an important cause of decreased osteogenic differentiation. A pharmacological increase in autophagy of BMSCs is a potential
OrthoInfo.org Offers Osteoporosis Awareness and Prevention Resources for Patients
This May, OrthoInfo.org, the authoritative and trusted source on bone and joint health, is joining organizations across the country to raise awareness about prevention strategies that can help reduce one’s risk of developing osteoporosis.
MD Anderson Research Highlights for March 20, 2024
The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention.
Silencing of Jumonji domain-containing 1C inhibits the osteogenic differentiation of bone marrow mesenchymal stem cells via nuclear factor-κB signaling
BACKGROUNDOsteoporosis is a common metabolic bone disorder induced by an imbalance between osteoclastic activity and osteogenic activity. During osteoporosis, bone mesenchymal stem cells (BMSCs) exhibit an increased ability to differentiate
Compounds in female ginseng could lead to new osteoporosis treatments
Drugs for treating osteoporosis can be expensive and have side effects. In the search for alternative drug candidates, researchers reporting in ACS Central Science have discovered and fully replicated a compound from female ginseng that had potent anti-osteoporotic activity in cellular tests.
AI identifies antimalarial drug as possible osteoporosis treatment
Artificial intelligence is being harnessed by some scientists to predict which molecules could treat illnesses. Researchers reporting in ACS Central Science have used one such deep learning algorithm, and found that an antimalarial drug could treat osteoporosis.
Experto de Mayo Clinic explica la importancia de mejorar la salud ósea antes de una cirugía de la columna vertebral
Tener huesos sanos es importante. Contribuyen al movimiento. Proporcionan estructura, sostienen los músculos y protegen el cerebro, el corazón y otros órganos de las lesiones. Los huesos almacenan minerales que se liberan en el organismo para diversos usos.
New Study to Examine Whether Medication and/or Resistance Training Plus Bone-Strengthening Exercises Can Help Older Adults Safely Lose Weight
With $7 million in funding from the National Institutes of Health, researchers from Wake Forest University School of Medicine and Wake Forest University will study whether a combination of resistance training plus bone-strengthening exercises and/or osteoporosis medication use can help older adults safely lose weight without sacrificing bone mass.
Social isolation linked to reduced bone quality in males, mouse study finds
Social isolation may negatively impact bone health, suggests a study conducted in mice being presented Sunday at ENDO 2023, the Endocrine Society’s annual meeting in Chicago, Ill.
Study finds “robotic pill” can safely deliver injectable osteoporosis drug
A proven and effective medication for osteoporosis, which is currently only available as an injection, can be administered orally using a novel “robotic pill,” according to a study presented Saturday at ENDO 2023, the Endocrine Society’s annual meeting in Chicago, Ill.
A commonly used tool is suboptimal in predicting osteoporosis fracture risk in younger post-menopausal women
The commonly used U.S version of the Fracture Risk Assessment Tool (FRAX) should not be routinely used to select younger postmenopausal women for bone mineral density testing. But the Osteoporosis Self-Assessment Tool (OST) is excellent at identifying women with osteoporosis-level bone mineral density, which is the goal of these screenings, while FRAX is not.
How old are your bones?
Researchers from The University of Technology Sydney (UTS) have measured the extent to which a bone fracture can lead to early death, and created a publicly available tool that doctors and patients can use to calculate risk.
News Tip: May Is National Osteoporosis Awareness And Prevention Month — Johns Hopkins Medicine Endocrinologists Are Available for Interviews
Osteoporosis — a condition that causes bones to become weak and more susceptible to fracture — affects more than 10 million Americans. It occurs when a person’s body does not properly replenish the components of their bone tissue.
During Osteoporosis Awareness Month, Those at Risk Urged to Bone Up on Silent Disease
National Osteoporosis Awareness Month in May is an opportune time to discuss ways to promote good bone health and take action if at risk, say experts at Hospital for Special Surgery. They provide helpful advice.
Study provides genetic evidence on new osteoporosis drug heart attack risk
New research highlights potential safety concerns around women taking romosozumab, a new anti-osteoporosis drug available on the NHS. The University of Bristol-led study, published in Arthritis & Rheumatology, analysed genetic data on nearly 34,000 people.
Osteoporosis treatments may benefit from discovery of key driver of low bone density
Scientists have pinpointed a key driver of low bone density, a discovery that may lead to improved treatments with fewer side effects for women with osteoporosis.
Study: Obstructive sleep apnea tied to weaker bones and teeth in adults
Obstructive sleep apnea may be linked to low bone mineral density in adults, according to University at Buffalo-led research. The findings are crucial for individuals with sleep apnea, as low bone mineral density is an indicator of osteoporosis – a condition in which bones become weak and brittle.
Study Explores Effects of Resistance Training in Older Adults at the Cellular Level
Aging and related diseases are associated with alterations in oxidative status and low-grade inflammation, as well as a decreased endoplasmic reticulum (ER) unfolded protein response (UPR). UPR is a functional mechanism by which cells attempt to protect themselves against ER stress. Researchers analyzed these proteins in peripheral blood mononuclear cells of elderly subjects and used computer simulation to predict the key proteins associated with these biomolecules underlying physiological adaptations to exercise. They collected blood samples about five to six days before and after the training period and analyzed various oxidative stress biomarkers in peripheral blood mononuclear cells. The study takes research one step further in helping to elucidate the benefits of exercise in this population.
American College of Physicians recommends bisphosphonates for initial treatment for osteoporosis in males and postmenopausal females diagnosed with primary osteoporosis
The American College of Physicians (ACP) has issued an update of its guideline with clinical recommendations for treatments of primary osteoporosis and low bone mass in adults.
World Osteoporosis Day is next week on October 20; Orthopaedic surgeons can help break down the signs and symptoms of this silent bone disease
ROSEMONT, Ill. (October 11, 2022)—Did you know that osteoporosis can cause bones to become so weak and fragile that they can break with the most minor bump, sudden movement or even sneeze? Often referred to as the “silent disease” because…
Updated Guideline Introduces Recommendations for Prevention and Treatment of Glucocorticoid-Induced Osteoporosis
The American College of Rheumatology (ACR) released a summary of its updated guideline for the Prevention and Treatment of Glucocorticoid-Induced Osteoporosis. New osteoporosis medications and new literature have become available since the last ACR treatment guideline was published in 2017.
New model can predict best drug combinations for osteoporosis
The model, described today in eLife, may help improve outcomes for patients with postmenopausal osteoporosis and reduce the risks of side effects by helping physicians build more personalised treatment regimes.
Vitamin D Supplements May Offset Bone Loss Caused by Diabetes Drug
Vitamin D supplementation may help offset damaging bone loss that occurs in some people who take canagliflozin, a commonly prescribed diabetes drug. Researchers will present their work this week at the American Physiological Society (APS) and American Society for Nephrology Control of Renal Function in Health and Disease conference in Charlottesville, Virginia.
Smoke Break: UNLV Study Strengthens Link Between Smoking and Increased Fracture Risk in Men
It’s no secret that puffing cigarettes is the culprit behind a host of ailments, including respiratory diseases and throat cancer. But a new UNLV study reveals that male smokers — who, demographically, are more likely than women to light up — are also placing themselves at a significantly increased risk of osteoporosis, bone fractures, and early death.
Cedars-Sinai Offers Program to Catch Older Adults Before They Fall
Falls and broken bones are common among older adults, but they’re not a natural part of aging. That’s why Cedars-Sinai geriatricians created a bone health and falls risk consultation program to catch at-risk people before they break a bone or help them avoid another fracture in the future.
A Prune—Or Six—a Day May Keep Inflammation at Bay
A study in postmenopausal people suggests eating nutrient-rich prunes every day may be beneficial to bone health, reducing inflammatory factors that contribute to osteoporosis. The research will be presented this week in Philadelphia at the American Physiological Society’s (APS) annual meeting at Experimental Biology 2022.
Study: Obesity raises the risk of gum disease by inflating growth of bone-destroying cells
Chronic inflammation caused by obesity may trigger the development of cells that break down bone tissue, including the bone that holds teeth in place, according to new University at Buffalo research that sought to improve understanding of the connection between obesity and gum disease.
Caffeine cuts close to the bone when it comes to osteoporosis
University of South Australia researchers have a bone to pick when it comes to drinking too much coffee as new research finds that excess caffeine may be linked to an increased risk of osteoporosis.
UTHealth expert publishes osteoporosis guide to help family medicine/primary care physicians care for their patients
An osteoporosis guide for primary care providers to better treat their patients has been published in the journal of Family Medicine by clinicians and researchers with The University of Texas Health Science Center at Houston (UTHealth).
June 2021 Issue of Neurosurgical Focus: “Biologics and Spinal Fusion”
Announcement of articles in the June 2021 issue of Neurosurgical Focus.
Osteoporosis: What You Need to Know About This “Silent Disease”
Osteoporosis, often synonymous with aging, is a silent disease that targets anyone regardless of age and gender.
Osteoporosis drug prescribing often does not follow guidelines
Less than one in 10 commercially insured patients in the United States who broke a hip, a major complication of osteoporosis, receive any osteoporosis medical treatment within two calendar quarters of their fracture, according to a study whose results will be presented at ENDO 2021, the Endocrine Society’s annual meeting.
Endocrine Society joins ASBMR and other bone health organizations to provide guidance on COVID-19 vaccine and osteoporosis
As COVID-19 vaccines continue to be distributed, the world’s leading bone health research, clinical, and patient advocacy organizations ASBMR, Endocrine Society, AACE, ECTS, NOF, and IOF provide recommendations to assist clinicians in managing osteoporosis treatments for their patients who plan to get vaccinated. The full guidance document with supporting evidence is available at https://www.asbmr.org/about/statement-detail/joint-guidance-on-covid-19-vaccine-osteoporosis
Study Reveals Connection Between Gut Bacteria and Vitamin D Levels
UC San Diego researchers discovered that the makeup of a person’s gut microbiome is linked to their levels of active vitamin D, and revealed a new understanding of vitamin D and how it’s typically measured.
Potential Cellular Target for Eliminating Bone Breakdown in Osteoporosis Found
By disabling a function of a set of cells in mice, researchers appear to have halted the process that breaks down bone, a likely boon for osteoporosis treatment
Romosozumab Substantially Builds Bone Density in Hip and Spine, With Even More Gains When Followed by Antiresorptive Drug
New research presented at ACR Convergence, the American College Rheumatology’s annual meeting, reveals that romosozumab, an osteoporosis drug, produces substantial gains in bone mineral density in the hip and lumbar spine within one year, and that transitioning patients to a potent antiresorptive drug can lead to even more bone density gains.
Osteoporosis Is Underdiagnosed and Undertreated in Older Men
A new study reveals that many older men who experience a fracture are still underdiagnosed with and undertreated for osteoporosis. Details of the study was presented at ACR Convergence, the American College Rheumatology’s annual meeting.
Mount Sinai Researchers Develop a First-in-Class Humanized Antibody Targeting Bone and Fat
Blocking the Follicle-Stimulating Hormone (FSH) whose levels rise at menopause could solve bone loss and weight gain Senior Author: Mone Zaidi, MD, PhD, MACP, Director of the Mount Sinai Bone Program and Professor of Medicine (Endocrinology, Diabetes and Bone Disease) at…
The ‘Goldilocks Day’: the perfect day for kids’ bone health
Not too little, not too much – Goldilocks’ ‘just right’ approach can now assess children’s daily activities as new research from the University of South Australia confirms the best make up of a child’s day to maximise bone health and function in children.
JNCCN: New Research Finds Low Bone Health Testing Rates after Prostate Cancer Treatment
New research in the October 2020 issue of JNCCN—Journal of the National Comprehensive Cancer Network finds the rate of bone mineral density (BMD) testing in people with prostate cancer undergoing androgen deprivation therapy (ADT) has improved in recent years, but remains low.
Research News Tip Sheet: Story Ideas From Johns Hopkins Medicine
During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every other Tuesday.
Ocean acidification causing coral ‘osteoporosis’ on iconic reefs
Scientists have long suspected that ocean acidification is affecting corals’ ability to build their skeletons, but it has been challenging to isolate its effect from that of simultaneous warming ocean temperatures, which also influence coral growth. New research from the Woods Hole Oceanographic Institution (WHOI) reveals the distinct impact that ocean acidification is having on coral growth on some of the world’s iconic reefs.
Breakthrough led by NUS researchers provides new potential therapies for osteoporosis
Researchers from the National University of Singapore have identified a new avenue to maintain bone health, which opens up new and potentially more effective osteoporosis treatments.
The August 2020 Issue of Neurosurgical Focus Examines Osteoporosis in the Lumbar Spine
Announcement of contents of Neurosurgical Focus’s August issue.
Two Widely-Used Drugs for Erectile Dysfunction Could Be Repurposed to Treat Osteoporosis
Why the Research Is Interesting: Osteoporosis is a global public health problem that affects almost 200 million people worldwide. Erectile dysfunction is the most common male sexual dysfunction in the aging population, with more than 70% of men over the…
Coalition of bone health experts issue joint guidance on managing osteoporosis in the COVID-19 era
The Endocrine Society joined a coalition of leading bone health organizations to release guidance for healthcare professionals treating patients with osteoporosis in the era of COVID-19.
Novel Research in AACC’s Clinical Chemistry Journal Shows That Vitamin D Supplements Do Not Prevent Osteoporotic Fractures
A first-of-its-kind study published in AACC’s Clinical Chemistry journal has found that low vitamin D levels alone do not cause osteoporotic fractures. This research could resolve the longstanding debate over whether vitamin D supplements prevent these fractures, and indicates that members of the general population should not rely on vitamin D by itself for this purpose.